SE9602280D0 - Immunstimulerande lipidformulering - Google Patents
Immunstimulerande lipidformuleringInfo
- Publication number
- SE9602280D0 SE9602280D0 SE9602280A SE9602280A SE9602280D0 SE 9602280 D0 SE9602280 D0 SE 9602280D0 SE 9602280 A SE9602280 A SE 9602280A SE 9602280 A SE9602280 A SE 9602280A SE 9602280 D0 SE9602280 D0 SE 9602280D0
- Authority
- SE
- Sweden
- Prior art keywords
- immune
- lipid formulation
- stimulating lipid
- carbon atoms
- stimulating
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/05—Actinobacteria, e.g. Actinomyces, Streptomyces, Nocardia, Bifidobacterium, Gardnerella, Corynebacterium; Propionibacterium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/145—Orthomyxoviridae, e.g. influenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/15—Reoviridae, e.g. calf diarrhea virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1274—Non-vesicle bilayer structures, e.g. liquid crystals, tubules, cubic phases, cochleates; Sponge phases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5252—Virus inactivated (killed)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/543—Mucosal route intranasal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
- C12N2720/00011—Details
- C12N2720/12011—Reoviridae
- C12N2720/12311—Rotavirus, e.g. rotavirus A
- C12N2720/12334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16151—Methods of production or purification of viral material
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Virology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Priority Applications (12)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9602280A SE9602280D0 (sv) | 1996-06-10 | 1996-06-10 | Immunstimulerande lipidformulering |
EP97927561A EP0918541B9 (en) | 1996-06-10 | 1997-06-09 | Immunstimulating lipid formulation |
NZ333226A NZ333226A (en) | 1996-06-10 | 1997-06-09 | Immunstimulating lipid formulation |
AU31998/97A AU724655B2 (en) | 1996-06-10 | 1997-06-09 | Immunstimulating lipid formulation |
ES97927561T ES2227698T3 (es) | 1996-06-10 | 1997-06-09 | Formulacion de lipidos inmunoestimuladores. |
JP50151498A JP4147328B2 (ja) | 1996-06-10 | 1997-06-09 | 免疫刺激するリピド製剤 |
DE69730434T DE69730434T2 (de) | 1996-06-10 | 1997-06-09 | Immunstimulierende lipidformulierung |
CA2258017A CA2258017C (en) | 1996-06-10 | 1997-06-09 | Immunstimulating lipid formulation |
PCT/SE1997/001003 WO1997047320A1 (en) | 1996-06-10 | 1997-06-09 | Immunstimulating lipid formulation |
US09/147,367 US7128909B2 (en) | 1996-06-10 | 1997-06-09 | Immunstimulating lipid formulation |
US11/524,192 US20070020282A1 (en) | 1996-06-10 | 2006-09-21 | Immunstimulating lipid formulation |
US12/076,981 US20080187553A1 (en) | 1996-06-10 | 2008-03-26 | Immunstimulating lipid formulation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9602280A SE9602280D0 (sv) | 1996-06-10 | 1996-06-10 | Immunstimulerande lipidformulering |
Publications (1)
Publication Number | Publication Date |
---|---|
SE9602280D0 true SE9602280D0 (sv) | 1996-06-10 |
Family
ID=20402941
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE9602280A SE9602280D0 (sv) | 1996-06-10 | 1996-06-10 | Immunstimulerande lipidformulering |
Country Status (10)
Country | Link |
---|---|
US (3) | US7128909B2 (xx) |
EP (1) | EP0918541B9 (xx) |
JP (1) | JP4147328B2 (xx) |
AU (1) | AU724655B2 (xx) |
CA (1) | CA2258017C (xx) |
DE (1) | DE69730434T2 (xx) |
ES (1) | ES2227698T3 (xx) |
NZ (1) | NZ333226A (xx) |
SE (1) | SE9602280D0 (xx) |
WO (1) | WO1997047320A1 (xx) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2001500738A (ja) | 1996-09-17 | 2001-01-23 | カイロン コーポレイション | 細胞内疾患を処置するための組成物および方法 |
IS4518A (is) * | 1997-07-09 | 1999-01-10 | Lyfjathroun Hf, The Icelandic Bio Pharmaceutical Group | Nýtt lyfjaform fyrir bóluefni |
SE9900496D0 (sv) | 1999-02-12 | 1999-02-12 | Pharmatrix Ab | Vaccine formulation |
SE9900495D0 (sv) * | 1999-02-12 | 1999-02-12 | Pharmatrix Ab | Vaccine composition |
SE0100011D0 (sv) * | 2001-01-03 | 2001-01-03 | Eurocine Ab Karolinska Inst Sc | Virus vaccine formulation |
US20030072764A1 (en) * | 2001-04-05 | 2003-04-17 | O'hagan Derek | Mucosal boosting following parenteral priming |
JP2005509598A (ja) * | 2001-08-16 | 2005-04-14 | リュフヤトルン・エイチエフ,バイオファーマシューティカルズ | エクスビボで抗体を産生する方法 |
AU2003215884A1 (en) * | 2002-02-25 | 2003-09-09 | Lyfjathroun Hf | A bioadhesive agent |
US6855332B2 (en) * | 2002-07-03 | 2005-02-15 | Lyfjathroun Hf. | Absorption promoting agent |
ATE480258T1 (de) * | 2002-11-26 | 2010-09-15 | Eurocine Vaccines Ab | Neue adjuvant auf der basis von aminen |
ES2375267T3 (es) | 2005-01-28 | 2012-02-28 | North-West University | Combinación de lípidos y de óxido nitroso como adyuvante para potenciar de la eficacia de vacunas. |
WO2008121926A1 (en) | 2007-03-30 | 2008-10-09 | Particle Sciences, Inc. | Particle formulations and uses thereof |
AU2010275475B2 (en) * | 2009-07-24 | 2013-10-03 | Spinal Usa, Inc. | Bone plate screw-blocking systems and methods |
BR112013007355A2 (pt) * | 2010-09-30 | 2016-07-12 | Eurocine Vaccines Ab | composições de vacina aprimoradas |
RU2483748C2 (ru) * | 2011-04-15 | 2013-06-10 | Леонид Леонидович Клопотенко | Фармацевтическая композиция, содержащая инсулин и липосомы, для местного применения в виде пластыря |
RU2483749C2 (ru) * | 2011-04-15 | 2013-06-10 | Леонид Леонидович Клопотенко | Фармацевтическая композиция, содержащая инсулин и липосомы, для местного применения в виде биопленки |
EP2742952A1 (en) | 2012-12-17 | 2014-06-18 | Eurocine Vaccines AB | Influenza vaccine composition |
TW202200012A (zh) | 2020-03-11 | 2022-01-01 | 美商富曼西公司 | 殺真菌劑混合物 |
TW202342431A (zh) | 2022-02-15 | 2023-11-01 | 美商富曼西公司 | 殺真菌的鹵代甲基酮、水合物和烯醇醚 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3531565A (en) * | 1969-09-25 | 1970-09-29 | American Cyanamid Co | Stable adjuvant emulsion compositions comprising hydrated salts of a polyvalent metallic cation and a higher fatty acid |
GB1374325A (en) * | 1972-10-05 | 1974-11-20 | Merck & Co Inc | Isomannide monooleate |
US4073743A (en) * | 1975-04-17 | 1978-02-14 | Merck & Co., Inc. | Process for preparing an emulsion |
US4446165A (en) * | 1979-06-08 | 1984-05-01 | The Procter & Gamble Company | Oleaginous compositions |
US5837249A (en) * | 1985-04-19 | 1998-11-17 | The Wistar Institute | Method for generating an immunogenic T cell response protective against a virus |
US4997851A (en) * | 1987-12-31 | 1991-03-05 | Isaacs Charles E | Antiviral and antibacterial activity of fatty acids and monoglycerides |
US5055446A (en) * | 1988-10-21 | 1991-10-08 | University Of Cincinnati | Method to improve survival of patients during sepsis by diet composition |
AU626049B2 (en) * | 1989-05-29 | 1992-07-23 | Lion Corporation | Method for preparing vaccine for dental caries and vaccinal compositions for dental caries used as nasal drop |
US5256641A (en) * | 1990-11-01 | 1993-10-26 | State Of Oregon | Covalent polar lipid-peptide conjugates for immunological targeting |
CA2114125A1 (en) * | 1991-07-26 | 1993-02-18 | Wayne G. Reilly | Self-adjuvanting peptide vaccine delivery system and production thereof |
WO1993006921A1 (en) * | 1991-10-04 | 1993-04-15 | Gs Biochem Ab | Particles, method of preparing said particles and uses thereof |
CA2083553A1 (en) | 1991-11-25 | 1993-05-26 | Kuniharu Seki | Immunogen composition |
US5576016A (en) * | 1993-05-18 | 1996-11-19 | Pharmos Corporation | Solid fat nanoemulsions as drug delivery vehicles |
BR9506885A (pt) | 1994-02-24 | 1997-08-19 | Micro Pak Inc | Vacinas contendo vesículas de lipidio paucilamelares como adjuvantes imunológicos |
US5739118A (en) * | 1994-04-01 | 1998-04-14 | Apollon, Inc. | Compositions and methods for delivery of genetic material |
JP3770628B2 (ja) * | 1994-08-09 | 2006-04-26 | サントリー株式会社 | 遅延型アレルギー反応を介する医学的症状の予防及び改善剤 |
US5730989A (en) * | 1995-02-16 | 1998-03-24 | Novavax, Inc. | Oral vaccine against gram negative bacterial infection |
-
1996
- 1996-06-10 SE SE9602280A patent/SE9602280D0/xx unknown
-
1997
- 1997-06-09 EP EP97927561A patent/EP0918541B9/en not_active Expired - Lifetime
- 1997-06-09 AU AU31998/97A patent/AU724655B2/en not_active Ceased
- 1997-06-09 ES ES97927561T patent/ES2227698T3/es not_active Expired - Lifetime
- 1997-06-09 WO PCT/SE1997/001003 patent/WO1997047320A1/en active IP Right Grant
- 1997-06-09 US US09/147,367 patent/US7128909B2/en not_active Expired - Fee Related
- 1997-06-09 NZ NZ333226A patent/NZ333226A/xx not_active IP Right Cessation
- 1997-06-09 DE DE69730434T patent/DE69730434T2/de not_active Expired - Lifetime
- 1997-06-09 CA CA2258017A patent/CA2258017C/en not_active Expired - Fee Related
- 1997-06-09 JP JP50151498A patent/JP4147328B2/ja not_active Expired - Lifetime
-
2006
- 2006-09-21 US US11/524,192 patent/US20070020282A1/en not_active Abandoned
-
2008
- 2008-03-26 US US12/076,981 patent/US20080187553A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA2258017C (en) | 2011-05-24 |
AU3199897A (en) | 1998-01-07 |
US20020012673A1 (en) | 2002-01-31 |
JP2000512292A (ja) | 2000-09-19 |
JP4147328B2 (ja) | 2008-09-10 |
US20080187553A1 (en) | 2008-08-07 |
EP0918541B1 (en) | 2004-08-25 |
AU724655B2 (en) | 2000-09-28 |
DE69730434D1 (de) | 2004-09-30 |
EP0918541A1 (en) | 1999-06-02 |
DE69730434T2 (de) | 2005-09-15 |
WO1997047320A1 (en) | 1997-12-18 |
CA2258017A1 (en) | 1997-12-18 |
EP0918541B9 (en) | 2008-06-18 |
ES2227698T3 (es) | 2005-04-01 |
US20070020282A1 (en) | 2007-01-25 |
NZ333226A (en) | 2000-05-26 |
US7128909B2 (en) | 2006-10-31 |
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