SE8306351L - SET TO MAKE L-SERIN - Google Patents

SET TO MAKE L-SERIN

Info

Publication number
SE8306351L
SE8306351L SE8306351A SE8306351A SE8306351L SE 8306351 L SE8306351 L SE 8306351L SE 8306351 A SE8306351 A SE 8306351A SE 8306351 A SE8306351 A SE 8306351A SE 8306351 L SE8306351 L SE 8306351L
Authority
SE
Sweden
Prior art keywords
serine
serin
make
biocatalytic
tetrahydrofolate
Prior art date
Application number
SE8306351A
Other languages
Unknown language ( )
Swedish (sv)
Other versions
SE8306351D0 (en
Inventor
D M Anderson
H-Y Hsiao
R Lamont
K M Herrmann
Original Assignee
Genex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genex Corp filed Critical Genex Corp
Publication of SE8306351D0 publication Critical patent/SE8306351D0/en
Publication of SE8306351L publication Critical patent/SE8306351L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1003—Transferases (2.) transferring one-carbon groups (2.1)
    • C12N9/1014—Hydroxymethyl-, formyl-transferases (2.1.2)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

A method of synthesizing L-serine from glycine and formaldehyde in the presence of biocatalytic amounts of serine hydroxymethyltransferase and tetrahydrofolate is disclosed. The serine hydroxymethyl- transferase may be amplified by cloning the gene therefor into a plasmid, and transforming a host cell, preferably Escherichia coli, Salmonella tymphimurium or Klebsiella aerogenes therewith.
SE8306351A 1982-11-19 1983-11-17 SET TO MAKE L-SERIN SE8306351L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US44296282A 1982-11-19 1982-11-19

Publications (2)

Publication Number Publication Date
SE8306351D0 SE8306351D0 (en) 1983-11-17
SE8306351L true SE8306351L (en) 1984-05-20

Family

ID=23758887

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8306351A SE8306351L (en) 1982-11-19 1983-11-17 SET TO MAKE L-SERIN

Country Status (20)

Country Link
JP (1) JPS59109187A (en)
AU (1) AU2149383A (en)
BE (1) BE898261A (en)
BR (1) BR8306301A (en)
CA (1) CA1217158A (en)
CH (1) CH657373A5 (en)
DE (1) DE3341763A1 (en)
DK (1) DK529583A (en)
ES (1) ES8602128A1 (en)
FI (1) FI834231A (en)
FR (1) FR2536415B1 (en)
GB (1) GB2130216B (en)
GR (1) GR79037B (en)
IL (1) IL70271A0 (en)
IT (1) IT8368213A0 (en)
LU (1) LU85096A1 (en)
NL (1) NL8303978A (en)
PL (1) PL244608A1 (en)
SE (1) SE8306351L (en)
ZA (1) ZA838642B (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4782021A (en) * 1984-02-17 1988-11-01 Mitsui Toatsu Chemicals, Inc. Method of producing L-serine
JPS60172293A (en) * 1984-02-17 1985-09-05 Mitsui Toatsu Chem Inc Preparation of l-serine
EP0165044A3 (en) * 1984-06-11 1987-09-30 Genex Corporation Method of reacting an aldehyde- containing compound with a nucleophilic compound
JPS6181775A (en) * 1984-08-30 1986-04-25 Rikagaku Kenkyusho Cultivation of microorganism
EP0185824A1 (en) * 1984-12-28 1986-07-02 Genex Corporation Stabilization of tetrahydrofolic acid and serine hydroxymethyltransferase in reaction mixtures for the enzymatic cynthesis of L-serine
JPS62502934A (en) * 1985-03-18 1987-11-26 ジエネツクス　コ−ポレ−シヨン Synthesis of L-tryptophan from glycine, formaldehyde and indole in the presence of serine hydroxymethyltransferase, tetrahydrofolate and tryptophan synthetase or tryptophanase
US4810817A (en) * 1985-10-21 1989-03-07 W. R. Grace & Co. Aspartyl-beta substituted phenylalanine dipeptides
US4873359A (en) * 1985-10-21 1989-10-10 W. R. Grace & Co. - Conn. Process for preparing as partyl-phenylalanine dipeptides
US5102792A (en) * 1987-08-13 1992-04-07 W. R. Grace & Co.-Conn. Selective production of L-serine derivative isomers
IL98312A0 (en) * 1990-06-04 1992-06-21 Univ Notre Dame Du Lac Process for preparation of beta-hydroxy-alpha-amino acids
US5266468A (en) * 1990-06-04 1993-11-30 University Of Notre Dame Du Lac Process for preparing β-hydroxy-α amino acids
IL109729A0 (en) * 1993-05-25 1994-08-26 Lilly Co Eli Process for preparing serine hydroxymethyl-transferase
DE10106461A1 (en) 2001-02-13 2002-08-14 Degussa Process for the fermentative production of D-pantothenic acid and / or its salts
CN104946695B (en) * 2015-06-03 2018-07-24 武汉轻工大学 A kind of preparation method of Serine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS582677B2 (en) * 1976-02-12 1983-01-18 田辺製薬株式会社 Production method of L-serine
GB2084155B (en) * 1980-09-17 1984-01-11 Grace W R & Co Process for production of l-amino acids using immobilized microorganisms

Also Published As

Publication number Publication date
FR2536415B1 (en) 1987-06-26
FI834231A (en) 1984-05-20
SE8306351D0 (en) 1983-11-17
IT8368213A0 (en) 1983-11-18
AU2149383A (en) 1984-05-24
IL70271A0 (en) 1984-02-29
GR79037B (en) 1984-10-02
DK529583A (en) 1984-05-20
BE898261A (en) 1984-03-16
NL8303978A (en) 1984-06-18
ES527388A0 (en) 1985-04-16
CA1217158A (en) 1987-01-27
FI834231A0 (en) 1983-11-18
GB8330859D0 (en) 1983-12-29
CH657373A5 (en) 1986-08-29
PL244608A1 (en) 1984-09-24
BR8306301A (en) 1984-07-03
DK529583D0 (en) 1983-11-18
ES8602128A1 (en) 1985-04-16
LU85096A1 (en) 1984-04-02
DE3341763A1 (en) 1984-10-04
ZA838642B (en) 1984-07-25
GB2130216B (en) 1986-04-16
FR2536415A1 (en) 1984-05-25
JPS59109187A (en) 1984-06-23
GB2130216A (en) 1984-05-31

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Effective date: 19851004