SE8207476D0 - NEW HETEROCYCLIC ACETIC ACID DERIVATIVES AND A PROCESS FOR THE PREPARATION THEREOF - Google Patents

NEW HETEROCYCLIC ACETIC ACID DERIVATIVES AND A PROCESS FOR THE PREPARATION THEREOF

Info

Publication number
SE8207476D0
SE8207476D0 SE8207476A SE8207476A SE8207476D0 SE 8207476 D0 SE8207476 D0 SE 8207476D0 SE 8207476 A SE8207476 A SE 8207476A SE 8207476 A SE8207476 A SE 8207476A SE 8207476 D0 SE8207476 D0 SE 8207476D0
Authority
SE
Sweden
Prior art keywords
general formula
image
new
defined above
preparation
Prior art date
Application number
SE8207476A
Other languages
Swedish (sv)
Other versions
SE8207476L (en
SE453084B (en
Inventor
K Lempert
G Doleschall
J Fetter
G Hornyak
J Nyitrai
G Simig
K Zauer
T Gizur
K Harsanyi
G Fekete
L Szporny
G Hajos
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of SE8207476D0 publication Critical patent/SE8207476D0/en
Publication of SE8207476L publication Critical patent/SE8207476L/en
Publication of SE453084B publication Critical patent/SE453084B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

New compounds of the general formula (I), <IMAGE> wherein Y<1> and Y<2> form together a removable carbonyl protecting group and X is a selectively removable esterifying group, are prepared in the way that a compound of the general formula (IV), <IMAGE> wherein Y<1> and Y<2> are as defined above, is nitrated and then reduced, the resulting new compound of the general formula (III), wherein <IMAGE> Y<1> and Y<2> are as defined above and A stands for nitro group and then for amino group, is converted into a new ester of the general formula (II), wherein Y<1>, Y<2> and X are as defined above, in a manner known per se, <IMAGE> and the aminophenyl protecting group of the resulting compound is split off. The new compounds of the general formula (I) can be applied primarily as intermediates in the synthesis of thienamycin or thienamycin analogues.
SE8207476A 1981-12-30 1982-12-29 AZETIDINON ETHYAC ACID DERIVATIVES AND PROCEDURES FOR PREPARING THEREOF SE453084B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU814013A HU184496B (en) 1981-12-30 1981-12-30 Process for producing new azetidinon-acetic acid derivatives

Publications (3)

Publication Number Publication Date
SE8207476D0 true SE8207476D0 (en) 1982-12-29
SE8207476L SE8207476L (en) 1983-07-01
SE453084B SE453084B (en) 1988-01-11

Family

ID=10966510

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8207476A SE453084B (en) 1981-12-30 1982-12-29 AZETIDINON ETHYAC ACID DERIVATIVES AND PROCEDURES FOR PREPARING THEREOF

Country Status (19)

Country Link
JP (1) JPS58118564A (en)
AT (1) AT378770B (en)
AU (1) AU555597B2 (en)
BE (1) BE895487A (en)
CA (1) CA1189866A (en)
CH (1) CH656123A5 (en)
DE (1) DE3248673A1 (en)
ES (1) ES8405762A1 (en)
FI (1) FI824519L (en)
FR (1) FR2518996B1 (en)
GB (1) GB2114125B (en)
GR (1) GR77071B (en)
HU (1) HU184496B (en)
IT (1) IT1210969B (en)
LU (1) LU84565A1 (en)
NL (1) NL8205068A (en)
PL (1) PL137594B1 (en)
SE (1) SE453084B (en)
ZA (1) ZA829594B (en)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT71553B (en) * 1979-07-23 1981-12-14 Merck & Co Inc Process for the preparation of thienamycin and intermediates
JPS57167964A (en) * 1981-04-09 1982-10-16 Toyama Chem Co Ltd Preparation of (4r)-3-substituted-4-(substituted or unsubstituted carboxymethyl)-2-azetidinone derivative
JPS57176982A (en) * 1981-04-24 1982-10-30 Shionogi & Co Ltd Dioxolanylazetidinone compound, its preparation and use

Also Published As

Publication number Publication date
CH656123A5 (en) 1986-06-13
GR77071B (en) 1984-09-05
AU9196982A (en) 1983-07-07
ZA829594B (en) 1983-10-26
ES518721A0 (en) 1984-06-16
FI824519A0 (en) 1982-12-30
DE3248673A1 (en) 1983-07-07
FR2518996B1 (en) 1986-02-28
SE8207476L (en) 1983-07-01
ES8405762A1 (en) 1984-06-16
GB2114125A (en) 1983-08-17
IT8225061A0 (en) 1982-12-30
LU84565A1 (en) 1984-10-22
NL8205068A (en) 1983-07-18
PL137594B1 (en) 1986-06-30
PL239886A1 (en) 1984-01-02
SE453084B (en) 1988-01-11
CA1189866A (en) 1985-07-02
HU184496B (en) 1984-08-28
ATA453282A (en) 1985-02-15
JPS58118564A (en) 1983-07-14
AU555597B2 (en) 1986-10-02
AT378770B (en) 1985-09-25
BE895487A (en) 1983-06-28
IT1210969B (en) 1989-09-29
FR2518996A1 (en) 1983-07-01
FI824519L (en) 1983-07-01
GB2114125B (en) 1985-09-25

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