JPS53108923A - Epoxysuccinylamino acid derivative - Google Patents
Epoxysuccinylamino acid derivativeInfo
- Publication number
- JPS53108923A JPS53108923A JP2309277A JP2309277A JPS53108923A JP S53108923 A JPS53108923 A JP S53108923A JP 2309277 A JP2309277 A JP 2309277A JP 2309277 A JP2309277 A JP 2309277A JP S53108923 A JPS53108923 A JP S53108923A
- Authority
- JP
- Japan
- Prior art keywords
- epoxysuccinylamino
- acid derivative
- alkali metal
- lower alkyl
- ethoxycarbonyloxyrane
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000002253 acid Substances 0.000 title 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 2
- 150000001340 alkali metals Chemical class 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 229940024606 amino acid Drugs 0.000 abstract 1
- 235000001014 amino acid Nutrition 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epoxy Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
PURPOSE: Title compound of formula I (R1 is H, alkali metal, lower alkyl, alkenyl, aryl; R2 is H, alkali metal, lower alkyl, aralkyl; A exibits skelton of aminoacid excluded amino and carboxyl groups; n is 1, 2), for example, N-(dl3-trans-ethoxycarbonyloxyrane-2-carbonyl)-L-phenylalanine ethyl ester.
COPYRIGHT: (C)1978,JPO&Japio
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP52023092A JPS6059232B2 (en) | 1977-03-03 | 1977-03-03 | Epoxysuccinyl amino acid derivatives |
GB4717/78A GB1595168A (en) | 1977-03-03 | 1978-02-06 | Expoxysuccinic acid derivatives |
FR7804933A FR2382447A1 (en) | 1977-03-03 | 1978-02-21 | PROCESS FOR PREPARATION OF EPOXYSUCCINIC ACID DERIVATIVES, NEW PRODUCTS THUS OBTAINED AND THEIR USE IN PARTICULAR FOR THEIR ANTI-INFLAMMATORY ACTIVITY |
US05/880,180 US4393228A (en) | 1977-03-03 | 1978-02-22 | Epoxysuccinic acid derivatives |
DE2809036A DE2809036C2 (en) | 1977-03-03 | 1978-03-02 | Trans-epoxysuccinic acid derivatives |
CA298,083A CA1110632A (en) | 1977-03-03 | 1978-03-02 | Epoxysuccinic acid derivatives |
BE185628A BE864505A (en) | 1977-03-03 | 1978-03-02 | PROCESS FOR PREPARATION OF EPOXYSUCCINIC ACID DERIVATIVES, NEW PRODUCTS THUS OBTAINED AND THEIR USE IN PARTICULAR FOR THEIR ANTI-INFLAMMATORY ACTIVITY |
CH229778A CH629492A5 (en) | 1977-03-03 | 1978-03-03 | EPOXYSUCCINIC ACID DERIVATIVES AND THEIR USE IN PARTICULAR FOR THEIR ANTI-INFLAMMATORY ACTIVITY. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP52023092A JPS6059232B2 (en) | 1977-03-03 | 1977-03-03 | Epoxysuccinyl amino acid derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS53108923A true JPS53108923A (en) | 1978-09-22 |
JPS6059232B2 JPS6059232B2 (en) | 1985-12-24 |
Family
ID=12100780
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP52023092A Expired JPS6059232B2 (en) | 1977-03-03 | 1977-03-03 | Epoxysuccinyl amino acid derivatives |
Country Status (2)
Country | Link |
---|---|
JP (1) | JPS6059232B2 (en) |
BE (1) | BE864505A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS56104880A (en) * | 1980-01-25 | 1981-08-20 | Nippon Chemiphar Co Ltd | Novel epoxysuccinic derivative and its preparation |
WO1999011640A1 (en) * | 1997-09-04 | 1999-03-11 | Nippon Chemiphar Co., Ltd. | Epoxysuccinamide derivatives |
-
1977
- 1977-03-03 JP JP52023092A patent/JPS6059232B2/en not_active Expired
-
1978
- 1978-03-02 BE BE185628A patent/BE864505A/en not_active IP Right Cessation
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS56104880A (en) * | 1980-01-25 | 1981-08-20 | Nippon Chemiphar Co Ltd | Novel epoxysuccinic derivative and its preparation |
JPH0149707B2 (en) * | 1980-01-25 | 1989-10-25 | Nippon Chemiphar Co | |
WO1999011640A1 (en) * | 1997-09-04 | 1999-03-11 | Nippon Chemiphar Co., Ltd. | Epoxysuccinamide derivatives |
Also Published As
Publication number | Publication date |
---|---|
JPS6059232B2 (en) | 1985-12-24 |
BE864505A (en) | 1978-09-04 |
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