JPS53108923A - Epoxysuccinylamino acid derivative - Google Patents

Epoxysuccinylamino acid derivative

Info

Publication number
JPS53108923A
JPS53108923A JP2309277A JP2309277A JPS53108923A JP S53108923 A JPS53108923 A JP S53108923A JP 2309277 A JP2309277 A JP 2309277A JP 2309277 A JP2309277 A JP 2309277A JP S53108923 A JPS53108923 A JP S53108923A
Authority
JP
Japan
Prior art keywords
epoxysuccinylamino
acid derivative
alkali metal
lower alkyl
ethoxycarbonyloxyrane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2309277A
Other languages
Japanese (ja)
Other versions
JPS6059232B2 (en
Inventor
Jiro Sawada
Kazunori Hanada
Masaharu Tamai
Shigeo Morimoto
Sadafumi Omura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Taisho Pharmaceutical Co Ltd
Original Assignee
Taisho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taisho Pharmaceutical Co Ltd filed Critical Taisho Pharmaceutical Co Ltd
Priority to JP52023092A priority Critical patent/JPS6059232B2/en
Priority to GB4717/78A priority patent/GB1595168A/en
Priority to FR7804933A priority patent/FR2382447A1/en
Priority to US05/880,180 priority patent/US4393228A/en
Priority to DE2809036A priority patent/DE2809036C2/en
Priority to CA298,083A priority patent/CA1110632A/en
Priority to BE185628A priority patent/BE864505A/en
Priority to CH229778A priority patent/CH629492A5/en
Publication of JPS53108923A publication Critical patent/JPS53108923A/en
Publication of JPS6059232B2 publication Critical patent/JPS6059232B2/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/48Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epoxy Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PURPOSE: Title compound of formula I (R1 is H, alkali metal, lower alkyl, alkenyl, aryl; R2 is H, alkali metal, lower alkyl, aralkyl; A exibits skelton of aminoacid excluded amino and carboxyl groups; n is 1, 2), for example, N-(dl3-trans-ethoxycarbonyloxyrane-2-carbonyl)-L-phenylalanine ethyl ester.
COPYRIGHT: (C)1978,JPO&Japio
JP52023092A 1977-03-03 1977-03-03 Epoxysuccinyl amino acid derivatives Expired JPS6059232B2 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
JP52023092A JPS6059232B2 (en) 1977-03-03 1977-03-03 Epoxysuccinyl amino acid derivatives
GB4717/78A GB1595168A (en) 1977-03-03 1978-02-06 Expoxysuccinic acid derivatives
FR7804933A FR2382447A1 (en) 1977-03-03 1978-02-21 PROCESS FOR PREPARATION OF EPOXYSUCCINIC ACID DERIVATIVES, NEW PRODUCTS THUS OBTAINED AND THEIR USE IN PARTICULAR FOR THEIR ANTI-INFLAMMATORY ACTIVITY
US05/880,180 US4393228A (en) 1977-03-03 1978-02-22 Epoxysuccinic acid derivatives
DE2809036A DE2809036C2 (en) 1977-03-03 1978-03-02 Trans-epoxysuccinic acid derivatives
CA298,083A CA1110632A (en) 1977-03-03 1978-03-02 Epoxysuccinic acid derivatives
BE185628A BE864505A (en) 1977-03-03 1978-03-02 PROCESS FOR PREPARATION OF EPOXYSUCCINIC ACID DERIVATIVES, NEW PRODUCTS THUS OBTAINED AND THEIR USE IN PARTICULAR FOR THEIR ANTI-INFLAMMATORY ACTIVITY
CH229778A CH629492A5 (en) 1977-03-03 1978-03-03 EPOXYSUCCINIC ACID DERIVATIVES AND THEIR USE IN PARTICULAR FOR THEIR ANTI-INFLAMMATORY ACTIVITY.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP52023092A JPS6059232B2 (en) 1977-03-03 1977-03-03 Epoxysuccinyl amino acid derivatives

Publications (2)

Publication Number Publication Date
JPS53108923A true JPS53108923A (en) 1978-09-22
JPS6059232B2 JPS6059232B2 (en) 1985-12-24

Family

ID=12100780

Family Applications (1)

Application Number Title Priority Date Filing Date
JP52023092A Expired JPS6059232B2 (en) 1977-03-03 1977-03-03 Epoxysuccinyl amino acid derivatives

Country Status (2)

Country Link
JP (1) JPS6059232B2 (en)
BE (1) BE864505A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56104880A (en) * 1980-01-25 1981-08-20 Nippon Chemiphar Co Ltd Novel epoxysuccinic derivative and its preparation
WO1999011640A1 (en) * 1997-09-04 1999-03-11 Nippon Chemiphar Co., Ltd. Epoxysuccinamide derivatives

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56104880A (en) * 1980-01-25 1981-08-20 Nippon Chemiphar Co Ltd Novel epoxysuccinic derivative and its preparation
JPH0149707B2 (en) * 1980-01-25 1989-10-25 Nippon Chemiphar Co
WO1999011640A1 (en) * 1997-09-04 1999-03-11 Nippon Chemiphar Co., Ltd. Epoxysuccinamide derivatives

Also Published As

Publication number Publication date
JPS6059232B2 (en) 1985-12-24
BE864505A (en) 1978-09-04

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