ES484115A1 - Aurone derivatives - Google Patents
Aurone derivativesInfo
- Publication number
- ES484115A1 ES484115A1 ES484115A ES484115A ES484115A1 ES 484115 A1 ES484115 A1 ES 484115A1 ES 484115 A ES484115 A ES 484115A ES 484115 A ES484115 A ES 484115A ES 484115 A1 ES484115 A1 ES 484115A1
- Authority
- ES
- Spain
- Prior art keywords
- chcooh
- tetrazol
- carboxyl
- formula
- aurone derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/32—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups
- C07C65/40—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups containing singly bound oxygen-containing groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/83—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/92—Naphthofurans; Hydrogenated naphthofurans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/30—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Pulmonology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Furan Compounds (AREA)
Abstract
Process for preparing aurone derivatives of formula I in which R1, R2, R3, R4, R5 and R6 are the same or different and can each represent hydrogen, halogen, C1-6 alkyl, C1-6 alkoxy, C3-cycloalkyl 8, optionally substituted phenyl, C1-6 haloalkyl, amido, amino, cyano, hydroxy, nitro, C2-4 alkenyl, carboxyl, tetrazol-5-yl or -CH = CHCOOH; or where R1 and R2 taken together represent a group of the formula -CH = CH-CH = CH-; provided that at least one of R1, R2, R3, R4, R5 and R6 is carboxyl, tetrazol-5-yl or -CH = CHCOOH; or a pharmaceutically acceptable salt or ester thereof. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB7836705 | 1978-09-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES484115A1 true ES484115A1 (en) | 1980-04-16 |
Family
ID=10499649
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES484115A Expired ES484115A1 (en) | 1978-09-13 | 1979-09-12 | Aurone derivatives |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | USRE32196E (en) |
| JP (1) | JPS5540692A (en) |
| KR (1) | KR830001919B1 (en) |
| AR (2) | AR228020A1 (en) |
| AT (1) | AT376968B (en) |
| AU (1) | AU535369B2 (en) |
| BG (2) | BG40315A3 (en) |
| CA (1) | CA1202309A (en) |
| CH (1) | CH644603A5 (en) |
| CS (1) | CS214806B2 (en) |
| DD (1) | DD146046A5 (en) |
| DK (1) | DK382579A (en) |
| EG (1) | EG14105A (en) |
| ES (1) | ES484115A1 (en) |
| FI (1) | FI792850A (en) |
| GR (1) | GR71200B (en) |
| HU (1) | HU181450B (en) |
| IE (1) | IE48824B1 (en) |
| IL (1) | IL58229A (en) |
| IT (1) | IT1162395B (en) |
| MX (1) | MX6232E (en) |
| NZ (1) | NZ191556A (en) |
| PH (1) | PH15712A (en) |
| PL (1) | PL124296B1 (en) |
| PT (1) | PT70170A (en) |
| SE (1) | SE447382B (en) |
| SU (1) | SU1138027A3 (en) |
| YU (1) | YU222079A (en) |
| ZA (1) | ZA794836B (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6307070B1 (en) | 1996-01-26 | 2001-10-23 | Phytera, Inc. | Substituted aurone derivatives |
| AU1709897A (en) * | 1996-01-26 | 1997-08-20 | Phytera, Inc. | Antimicrobial aurone derivatives |
| AU751213B2 (en) * | 1997-07-25 | 2002-08-08 | Phytera, Inc. | Substituted aurone derivatives |
| AU9001698A (en) * | 1997-09-11 | 1999-03-29 | Snow Brand Milk Products Co., Ltd. | Remedies for hormone-dependent diseases |
| EP1250331B1 (en) * | 2000-01-28 | 2004-11-03 | MERCK PATENT GmbH | Formulation for protection against oxidative stress containing benzofuranone derivatives |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT277985B (en) * | 1967-11-14 | 1970-01-12 | Schering Ag | Process for the preparation of new nitro-furan, -thiophene or -pyrrole derivatives |
| US4115567A (en) * | 1973-12-27 | 1978-09-19 | Carlo Erba S. P. A. | 6-Carboxy-2-(2'-pyrazinyl)-chromones and esters thereof |
| US3975380A (en) * | 1974-06-03 | 1976-08-17 | Smithkline Corporation | Substituted aurones |
| US4067993A (en) * | 1975-09-24 | 1978-01-10 | Riker Laboratories, Inc. | Antimicrobial 2-nitro-3-phenylbenzofurancarboxylic acids |
| US4143145A (en) * | 1977-01-12 | 1979-03-06 | Carlo Erba S. P. A. | Substituted 2-vinyl-chromones and process for their preparation |
| FR2396756A1 (en) * | 1977-07-06 | 1979-02-02 | Inst Nat Sante Rech Med | NEW BENZYLIDENE-2-BENZOFURANNONES-3, THEIR OBTAINING AND THEIR APPLICATION AS MEDICINAL PRODUCTS |
| IT1093805B (en) * | 1978-01-31 | 1985-07-26 | Erba Carlo Spa | DERIVATIVES OF 2H-BENZOFURAN-3-ONE AND PROCEDURE FOR THEIR PREPARATION |
| US4143055A (en) * | 1978-03-27 | 1979-03-06 | Gruppo Lepetit S.P.A. | 2,4,6-trisubstituted-2,3-dihydro-benzofuran derivatives |
-
1979
- 1979-09-11 GR GR60011A patent/GR71200B/el unknown
- 1979-09-11 IL IL58229A patent/IL58229A/en unknown
- 1979-09-11 AR AR278010A patent/AR228020A1/en active
- 1979-09-11 CH CH820379A patent/CH644603A5/en not_active IP Right Cessation
- 1979-09-11 AT AT0598079A patent/AT376968B/en not_active IP Right Cessation
- 1979-09-11 EG EG544/79A patent/EG14105A/en active
- 1979-09-11 SE SE7907532A patent/SE447382B/en not_active IP Right Cessation
- 1979-09-12 ES ES484115A patent/ES484115A1/en not_active Expired
- 1979-09-12 BG BG8046265A patent/BG40315A3/en unknown
- 1979-09-12 MX MX798376U patent/MX6232E/en unknown
- 1979-09-12 IE IE1729/79A patent/IE48824B1/en unknown
- 1979-09-12 YU YU02220/79A patent/YU222079A/en unknown
- 1979-09-12 BG BG7944838A patent/BG43187A3/en unknown
- 1979-09-12 DD DD79215501A patent/DD146046A5/en unknown
- 1979-09-12 CA CA000335522A patent/CA1202309A/en not_active Expired
- 1979-09-12 DK DK382579A patent/DK382579A/en not_active Application Discontinuation
- 1979-09-12 SU SU792816201A patent/SU1138027A3/en active
- 1979-09-12 IT IT50245/79A patent/IT1162395B/en active
- 1979-09-12 PH PH23026A patent/PH15712A/en unknown
- 1979-09-12 NZ NZ191556A patent/NZ191556A/en unknown
- 1979-09-12 HU HU79LI349A patent/HU181450B/en unknown
- 1979-09-12 AU AU50780/79A patent/AU535369B2/en not_active Ceased
- 1979-09-12 ZA ZA00794836A patent/ZA794836B/en unknown
- 1979-09-12 PT PT70170A patent/PT70170A/en unknown
- 1979-09-13 FI FI792850A patent/FI792850A/en not_active Application Discontinuation
- 1979-09-13 KR KR1019790003145A patent/KR830001919B1/en active
- 1979-09-13 JP JP11781279A patent/JPS5540692A/en active Pending
- 1979-09-13 PL PL1979218277A patent/PL124296B1/en unknown
- 1979-09-13 CS CS796201A patent/CS214806B2/en unknown
-
1981
- 1981-05-06 AR AR285217A patent/AR226210A1/en active
-
1982
- 1982-05-19 US US06/379,793 patent/USRE32196E/en not_active Expired - Lifetime
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES232723A1 (en) | Fatty acid amides and derivatives thereof | |
| RO75303A (en) | PROCESS FOR PREPARATION OF N- [P- (2,4-DIAMINO-6-PERIDINYL) -METHYL] -N-METHYLAMINO-BENZOYLGLUTAMIDE | |
| ES484115A1 (en) | Aurone derivatives | |
| JPS51118772A (en) | Method for preparing carbostyryl derivatives | |
| SE425395B (en) | PROCEDURE FOR THE PREPARATION OF PHENYL OR BENZYL PHOSPHONATE ESTERS | |
| JPS5297934A (en) | N#-arylsulfonyl-l-argininamides and their salts acceptable as medicine s | |
| ES475120A1 (en) | Imidazopyridazines and their use as therapeutic agents | |
| JPS5325533A (en) | Novel phenylacetic acid derivatives | |
| JPS5214773A (en) | Process for preparing novel benzylpyridine derivatives | |
| JPS5283565A (en) | Novel benzylpyridine derivatives | |
| JPS51113846A (en) | New herbicides | |
| JPS51118799A (en) | Method for preparing pyridindole derivatives | |
| JPS5359656A (en) | Silacyclopropene derivatives and process for preparation of the same | |
| JPS51136693A (en) | Process for preparing cephalosporins. | |
| JPS53108923A (en) | Epoxysuccinylamino acid derivative | |
| JPS51136653A (en) | Process for preparing novel organophosphorous compounds | |
| JPS51146474A (en) | Process for preparing piperidylbenzimidazole derivatives | |
| JPS5283722A (en) | Dipeptide derivatives | |
| JPS52113952A (en) | Aminobenzophenone derivatives | |
| JPS5711975A (en) | Aminophenyltetrazole derivative and salt thereof | |
| JPS5210219A (en) | Preparation of beta-sulfonylacrylic beta-sulfonylacrylic their esters and acids their esters and amides | |
| JPS5227757A (en) | Preparation of 6-aminomethylnaphthalene derivatives | |
| JPS51125281A (en) | A process for preparing indazole derivatives | |
| ES458021A1 (en) | Prostenoic acid derivatives | |
| JPS527935A (en) | Preparation of substituted phenylacetic acid derivatives |