SE7907432L - Alfa-aryl-alfa, alfa-bis (omega-(disubstituerad amino)alkyl)- acetamider och beslektade foreningar - Google Patents
Alfa-aryl-alfa, alfa-bis (omega-(disubstituerad amino)alkyl)- acetamider och beslektade foreningarInfo
- Publication number
- SE7907432L SE7907432L SE7907432A SE7907432A SE7907432L SE 7907432 L SE7907432 L SE 7907432L SE 7907432 A SE7907432 A SE 7907432A SE 7907432 A SE7907432 A SE 7907432A SE 7907432 L SE7907432 L SE 7907432L
- Authority
- SE
- Sweden
- Prior art keywords
- alkyl
- alfa
- substituted
- compounds
- acetamides
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- -1 AMINO Chemical class 0.000 title abstract 3
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 4
- 125000006701 (C1-C7) alkyl group Chemical group 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 1
- 125000001637 1-naphthyl group Chemical group [H]C1=C([H])C([H])=C2C(*)=C([H])C([H])=C([H])C2=C1[H] 0.000 abstract 1
- 125000001622 2-naphthyl group Chemical group [H]C1=C([H])C([H])=C2C([H])=C(*)C([H])=C([H])C2=C1[H] 0.000 abstract 1
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 abstract 1
- 150000007960 acetonitrile Chemical class 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 239000003416 antiarrhythmic agent Substances 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 150000002825 nitriles Chemical class 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 235000011149 sulphuric acid Nutrition 0.000 abstract 1
- 239000001117 sulphuric acid Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/940,527 US4217306A (en) | 1978-05-01 | 1978-09-08 | α-Aryl-α,α-bis[ω-(disubstituted amino)alkyl]-acetamides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE7907432L true SE7907432L (sv) | 1980-03-09 |
Family
ID=25474978
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7907432A SE7907432L (sv) | 1978-09-08 | 1979-09-07 | Alfa-aryl-alfa, alfa-bis (omega-(disubstituerad amino)alkyl)- acetamider och beslektade foreningar |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US4217306A (de) |
| JP (1) | JPS5592350A (de) |
| AT (3) | AT364813B (de) |
| AU (1) | AU5068679A (de) |
| BE (1) | BE878662A (de) |
| CA (1) | CA1136622A (de) |
| DE (1) | DE2936287A1 (de) |
| DK (1) | DK374879A (de) |
| ES (1) | ES483985A1 (de) |
| FR (1) | FR2435462A1 (de) |
| GB (1) | GB2030984B (de) |
| GR (1) | GR72494B (de) |
| IL (1) | IL58200A (de) |
| IT (1) | IT1120561B (de) |
| NL (1) | NL7906745A (de) |
| NO (1) | NO792901L (de) |
| NZ (1) | NZ191505A (de) |
| PT (1) | PT70151B (de) |
| SE (1) | SE7907432L (de) |
| ZA (1) | ZA794764B (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4639524A (en) * | 1984-07-09 | 1987-01-27 | G. D. Searle & Co. | Monobasic disobutamide derivatives |
| US5097035A (en) * | 1984-07-09 | 1992-03-17 | G. D. Searle & Co. | Monobasic disobutamide derivatives |
| US4791199A (en) * | 1985-09-19 | 1988-12-13 | G. D. Searle & Co. | Process for antiarrhythmic 1,3-diazabicyclo[4.4.0]dec-2-en-4-ones |
| EP0370712A3 (de) * | 1988-11-18 | 1991-10-02 | Ajinomoto Co., Inc. | Ethylamin-Derivate und kreislaufbeeinflussende Mittel, die sie enthalten |
| FR2686339B1 (fr) * | 1992-01-22 | 1994-03-11 | Adir Cie | Nouveaux amides et sulfonamides naphtaleniques, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent. |
| US5432284A (en) * | 1993-09-08 | 1995-07-11 | G. D. Searle & Co. | Process for the preparation of heterocyclic alkylamide derivatives |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2884436A (en) * | 1954-08-28 | 1959-04-28 | Nl Combinatie Chem Ind | Parasympathicolytically active alpha, alpha-diphenyl-gamma-dialkylaminobutyramide compounds and manufacture thereof |
| US3022314A (en) * | 1955-06-20 | 1962-02-20 | Upjohn Co | Alpha-phenyl-omega-amino-alkanamides |
| US3022302A (en) * | 1956-03-15 | 1962-02-20 | Pharmacia Ab | Manufacture of nu, nu-disubstituted amides of aryl acetic acids |
| US3078275A (en) * | 1956-05-28 | 1963-02-19 | Upjohn Co | N, n-disubstituted-alpha-(tertiaryaminoalkyl)-alpha, alpha-diphenylacetamides |
| US2894955A (en) * | 1956-11-19 | 1959-07-14 | Upjohn Co | Organic compounds |
| US3225091A (en) * | 1962-02-01 | 1965-12-21 | Lilly Co Eli | Anticholinergic substituted butyramides |
| NL124729C (de) | 1963-05-14 | |||
| BE689347A (de) | 1965-12-09 | 1967-04-14 | Madan Ag | |
| BE673495A (fr) | 1965-12-09 | 1966-04-01 | Madan Ag | Amides et N-hydroxyamides dérivés d'acides para-alkyloxyarylacétiques substitués et leur préparation |
| US4107205A (en) * | 1977-03-11 | 1978-08-15 | G. D. Searle & Co. | α-Aryl-α,α-bis[ω-(disubstituted amino)alkyl]acetamides and related compounds |
-
1978
- 1978-09-08 US US05/940,527 patent/US4217306A/en not_active Expired - Lifetime
-
1979
- 1979-09-07 ZA ZA00794764A patent/ZA794764B/xx unknown
- 1979-09-07 ES ES483985A patent/ES483985A1/es not_active Expired
- 1979-09-07 CA CA000335200A patent/CA1136622A/en not_active Expired
- 1979-09-07 AT AT0592679A patent/AT364813B/de not_active IP Right Cessation
- 1979-09-07 FR FR7922468A patent/FR2435462A1/fr active Pending
- 1979-09-07 IT IT50202/79A patent/IT1120561B/it active
- 1979-09-07 AU AU50686/79A patent/AU5068679A/en not_active Abandoned
- 1979-09-07 GB GB7931218A patent/GB2030984B/en not_active Expired
- 1979-09-07 DE DE19792936287 patent/DE2936287A1/de not_active Withdrawn
- 1979-09-07 NO NO792901A patent/NO792901L/no unknown
- 1979-09-07 SE SE7907432A patent/SE7907432L/xx not_active Application Discontinuation
- 1979-09-07 PT PT70151A patent/PT70151B/pt unknown
- 1979-09-07 IL IL58200A patent/IL58200A/xx unknown
- 1979-09-07 BE BE0/197051A patent/BE878662A/fr unknown
- 1979-09-07 DK DK374879A patent/DK374879A/da not_active Application Discontinuation
- 1979-09-07 NZ NZ191505A patent/NZ191505A/xx unknown
- 1979-09-07 JP JP11508979A patent/JPS5592350A/ja active Pending
- 1979-09-07 GR GR59993A patent/GR72494B/el unknown
- 1979-09-10 NL NL7906745A patent/NL7906745A/nl not_active Application Discontinuation
-
1980
- 1980-12-10 AT AT0600280A patent/AT370088B/de not_active IP Right Cessation
- 1980-12-10 AT AT0600180A patent/AT370087B/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5592350A (en) | 1980-07-12 |
| BE878662A (fr) | 1980-03-07 |
| AT370087B (de) | 1983-02-25 |
| DK374879A (da) | 1980-03-09 |
| GR72494B (de) | 1983-11-15 |
| GB2030984B (en) | 1983-07-27 |
| ATA600180A (de) | 1982-07-15 |
| FR2435462A1 (fr) | 1980-04-04 |
| CA1136622A (en) | 1982-11-30 |
| PT70151A (en) | 1979-09-01 |
| US4217306A (en) | 1980-08-12 |
| AT370088B (de) | 1983-02-25 |
| GB2030984A (en) | 1980-04-16 |
| NZ191505A (en) | 1982-03-30 |
| AT364813B (de) | 1981-11-25 |
| ES483985A1 (es) | 1980-04-16 |
| NL7906745A (nl) | 1980-03-11 |
| AU5068679A (en) | 1980-03-27 |
| ATA592679A (de) | 1981-04-15 |
| NO792901L (no) | 1980-03-11 |
| IL58200A (en) | 1982-12-31 |
| ATA600280A (de) | 1982-07-15 |
| DE2936287A1 (de) | 1980-03-20 |
| IL58200A0 (en) | 1979-12-30 |
| IT7950202A0 (it) | 1979-09-07 |
| PT70151B (pt) | 1981-12-11 |
| IT1120561B (it) | 1986-03-26 |
| ZA794764B (en) | 1981-04-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NAV | Patent application has lapsed |
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