AT370088B - Verfahren zur herstellung von neuen alpha-aryl-alpha, alpha-bis-(omega (disubstituiert-amino)-alkyl)acetamiden - Google Patents

Verfahren zur herstellung von neuen alpha-aryl-alpha, alpha-bis-(omega (disubstituiert-amino)-alkyl)acetamiden

Info

Publication number
AT370088B
AT370088B AT0600280A AT600280A AT370088B AT 370088 B AT370088 B AT 370088B AT 0600280 A AT0600280 A AT 0600280A AT 600280 A AT600280 A AT 600280A AT 370088 B AT370088 B AT 370088B
Authority
AT
Austria
Prior art keywords
alpha
disubstituated
acetamides
omega
aryl
Prior art date
Application number
AT0600280A
Other languages
English (en)
Other versions
ATA600280A (de
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Priority to AT0600280A priority Critical patent/AT370088B/de
Publication of ATA600280A publication Critical patent/ATA600280A/de
Application granted granted Critical
Publication of AT370088B publication Critical patent/AT370088B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT0600280A 1978-09-08 1980-12-10 Verfahren zur herstellung von neuen alpha-aryl-alpha, alpha-bis-(omega (disubstituiert-amino)-alkyl)acetamiden AT370088B (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT0600280A AT370088B (de) 1978-09-08 1980-12-10 Verfahren zur herstellung von neuen alpha-aryl-alpha, alpha-bis-(omega (disubstituiert-amino)-alkyl)acetamiden

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US05/940,527 US4217306A (en) 1978-05-01 1978-09-08 α-Aryl-α,α-bis[ω-(disubstituted amino)alkyl]-acetamides
AT0592679A AT364813B (de) 1978-09-08 1979-09-07 Verfahren zur herstellung von alpha-aryl-alpha, alpha-di(omega-aminoalkyl)acetamiden mit disubstituierter aminogruppe
AT0600280A AT370088B (de) 1978-09-08 1980-12-10 Verfahren zur herstellung von neuen alpha-aryl-alpha, alpha-bis-(omega (disubstituiert-amino)-alkyl)acetamiden

Publications (2)

Publication Number Publication Date
ATA600280A ATA600280A (de) 1982-07-15
AT370088B true AT370088B (de) 1983-02-25

Family

ID=25474978

Family Applications (3)

Application Number Title Priority Date Filing Date
AT0592679A AT364813B (de) 1978-09-08 1979-09-07 Verfahren zur herstellung von alpha-aryl-alpha, alpha-di(omega-aminoalkyl)acetamiden mit disubstituierter aminogruppe
AT0600280A AT370088B (de) 1978-09-08 1980-12-10 Verfahren zur herstellung von neuen alpha-aryl-alpha, alpha-bis-(omega (disubstituiert-amino)-alkyl)acetamiden
AT0600180A AT370087B (de) 1978-09-08 1980-12-10 Verfahren zur herstellung neuer symmetrischer alpha-aryl-alpha, alpha-di(omega(diisopropylamino)alkyl)acetamide

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT0592679A AT364813B (de) 1978-09-08 1979-09-07 Verfahren zur herstellung von alpha-aryl-alpha, alpha-di(omega-aminoalkyl)acetamiden mit disubstituierter aminogruppe

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT0600180A AT370087B (de) 1978-09-08 1980-12-10 Verfahren zur herstellung neuer symmetrischer alpha-aryl-alpha, alpha-di(omega(diisopropylamino)alkyl)acetamide

Country Status (21)

Country Link
US (1) US4217306A (de)
JP (1) JPS5592350A (de)
AT (3) AT364813B (de)
AU (1) AU5068679A (de)
BE (1) BE878662A (de)
CA (1) CA1136622A (de)
DE (1) DE2936287A1 (de)
DK (1) DK374879A (de)
ES (1) ES483985A1 (de)
FI (1) FI792780A (de)
FR (1) FR2435462A1 (de)
GB (1) GB2030984B (de)
GR (1) GR72494B (de)
IL (1) IL58200A (de)
IT (1) IT1120561B (de)
NL (1) NL7906745A (de)
NO (1) NO792901L (de)
NZ (1) NZ191505A (de)
PT (1) PT70151B (de)
SE (1) SE7907432L (de)
ZA (1) ZA794764B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5097035A (en) * 1984-07-09 1992-03-17 G. D. Searle & Co. Monobasic disobutamide derivatives
US4639524A (en) * 1984-07-09 1987-01-27 G. D. Searle & Co. Monobasic disobutamide derivatives
US4791199A (en) * 1985-09-19 1988-12-13 G. D. Searle & Co. Process for antiarrhythmic 1,3-diazabicyclo[4.4.0]dec-2-en-4-ones
EP0370712A3 (de) * 1988-11-18 1991-10-02 Ajinomoto Co., Inc. Ethylamin-Derivate und kreislaufbeeinflussende Mittel, die sie enthalten
FR2686339B1 (fr) * 1992-01-22 1994-03-11 Adir Cie Nouveaux amides et sulfonamides naphtaleniques, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
US5432284A (en) * 1993-09-08 1995-07-11 G. D. Searle & Co. Process for the preparation of heterocyclic alkylamide derivatives

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2884436A (en) * 1954-08-28 1959-04-28 Nl Combinatie Chem Ind Parasympathicolytically active alpha, alpha-diphenyl-gamma-dialkylaminobutyramide compounds and manufacture thereof
US3022314A (en) * 1955-06-20 1962-02-20 Upjohn Co Alpha-phenyl-omega-amino-alkanamides
US3022302A (en) * 1956-03-15 1962-02-20 Pharmacia Ab Manufacture of nu, nu-disubstituted amides of aryl acetic acids
US3078275A (en) * 1956-05-28 1963-02-19 Upjohn Co N, n-disubstituted-alpha-(tertiaryaminoalkyl)-alpha, alpha-diphenylacetamides
US2894955A (en) * 1956-11-19 1959-07-14 Upjohn Co Organic compounds
US3225091A (en) * 1962-02-01 1965-12-21 Lilly Co Eli Anticholinergic substituted butyramides
NL124729C (de) * 1963-05-14
US4107205A (en) * 1977-03-11 1978-08-15 G. D. Searle & Co. α-Aryl-α,α-bis[ω-(disubstituted amino)alkyl]acetamides and related compounds

Also Published As

Publication number Publication date
ATA600180A (de) 1982-07-15
CA1136622A (en) 1982-11-30
IL58200A0 (en) 1979-12-30
DE2936287A1 (de) 1980-03-20
ES483985A1 (es) 1980-04-16
GB2030984A (en) 1980-04-16
ZA794764B (en) 1981-04-29
FR2435462A1 (fr) 1980-04-04
NZ191505A (en) 1982-03-30
FI792780A (fi) 1980-03-09
GB2030984B (en) 1983-07-27
AT370087B (de) 1983-02-25
JPS5592350A (en) 1980-07-12
IT7950202A0 (it) 1979-09-07
NL7906745A (nl) 1980-03-11
ATA600280A (de) 1982-07-15
NO792901L (no) 1980-03-11
PT70151B (pt) 1981-12-11
US4217306A (en) 1980-08-12
AU5068679A (en) 1980-03-27
IL58200A (en) 1982-12-31
IT1120561B (it) 1986-03-26
DK374879A (da) 1980-03-09
BE878662A (fr) 1980-03-07
SE7907432L (sv) 1980-03-09
AT364813B (de) 1981-11-25
PT70151A (en) 1979-09-01
ATA592679A (de) 1981-04-15
GR72494B (de) 1983-11-15

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee