IT1120561B - Derivati alfa-aril-alfa alfa-bis omega-ammino bisostituiti alchilacetammidici ditati di proprieta' farmacologiche antiaritmia - Google Patents
Derivati alfa-aril-alfa alfa-bis omega-ammino bisostituiti alchilacetammidici ditati di proprieta' farmacologiche antiaritmiaInfo
- Publication number
- IT1120561B IT1120561B IT50202/79A IT5020279A IT1120561B IT 1120561 B IT1120561 B IT 1120561B IT 50202/79 A IT50202/79 A IT 50202/79A IT 5020279 A IT5020279 A IT 5020279A IT 1120561 B IT1120561 B IT 1120561B
- Authority
- IT
- Italy
- Prior art keywords
- alpha
- acetamidic
- arrhythmia
- facts
- omega
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/940,527 US4217306A (en) | 1978-05-01 | 1978-09-08 | α-Aryl-α,α-bis[ω-(disubstituted amino)alkyl]-acetamides |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT7950202A0 IT7950202A0 (it) | 1979-09-07 |
| IT1120561B true IT1120561B (it) | 1986-03-26 |
Family
ID=25474978
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT50202/79A IT1120561B (it) | 1978-09-08 | 1979-09-07 | Derivati alfa-aril-alfa alfa-bis omega-ammino bisostituiti alchilacetammidici ditati di proprieta' farmacologiche antiaritmia |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US4217306A (it) |
| JP (1) | JPS5592350A (it) |
| AT (3) | AT364813B (it) |
| AU (1) | AU5068679A (it) |
| BE (1) | BE878662A (it) |
| CA (1) | CA1136622A (it) |
| DE (1) | DE2936287A1 (it) |
| DK (1) | DK374879A (it) |
| ES (1) | ES483985A1 (it) |
| FI (1) | FI792780A (it) |
| FR (1) | FR2435462A1 (it) |
| GB (1) | GB2030984B (it) |
| GR (1) | GR72494B (it) |
| IL (1) | IL58200A (it) |
| IT (1) | IT1120561B (it) |
| NL (1) | NL7906745A (it) |
| NO (1) | NO792901L (it) |
| NZ (1) | NZ191505A (it) |
| PT (1) | PT70151B (it) |
| SE (1) | SE7907432L (it) |
| ZA (1) | ZA794764B (it) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4639524A (en) * | 1984-07-09 | 1987-01-27 | G. D. Searle & Co. | Monobasic disobutamide derivatives |
| US5097035A (en) * | 1984-07-09 | 1992-03-17 | G. D. Searle & Co. | Monobasic disobutamide derivatives |
| US4791199A (en) * | 1985-09-19 | 1988-12-13 | G. D. Searle & Co. | Process for antiarrhythmic 1,3-diazabicyclo[4.4.0]dec-2-en-4-ones |
| EP0370712A3 (en) * | 1988-11-18 | 1991-10-02 | Ajinomoto Co., Inc. | Ethylamine derivatives and hypotensives containing the same |
| FR2686339B1 (fr) * | 1992-01-22 | 1994-03-11 | Adir Cie | Nouveaux amides et sulfonamides naphtaleniques, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent. |
| US5432284A (en) * | 1993-09-08 | 1995-07-11 | G. D. Searle & Co. | Process for the preparation of heterocyclic alkylamide derivatives |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2884436A (en) * | 1954-08-28 | 1959-04-28 | Nl Combinatie Chem Ind | Parasympathicolytically active alpha, alpha-diphenyl-gamma-dialkylaminobutyramide compounds and manufacture thereof |
| US3022314A (en) * | 1955-06-20 | 1962-02-20 | Upjohn Co | Alpha-phenyl-omega-amino-alkanamides |
| US3022302A (en) * | 1956-03-15 | 1962-02-20 | Pharmacia Ab | Manufacture of nu, nu-disubstituted amides of aryl acetic acids |
| US3078275A (en) * | 1956-05-28 | 1963-02-19 | Upjohn Co | N, n-disubstituted-alpha-(tertiaryaminoalkyl)-alpha, alpha-diphenylacetamides |
| US2894955A (en) * | 1956-11-19 | 1959-07-14 | Upjohn Co | Organic compounds |
| US3225091A (en) * | 1962-02-01 | 1965-12-21 | Lilly Co Eli | Anticholinergic substituted butyramides |
| NL124729C (it) * | 1963-05-14 | |||
| US4107205A (en) * | 1977-03-11 | 1978-08-15 | G. D. Searle & Co. | α-Aryl-α,α-bis[ω-(disubstituted amino)alkyl]acetamides and related compounds |
-
1978
- 1978-09-08 US US05/940,527 patent/US4217306A/en not_active Expired - Lifetime
-
1979
- 1979-09-07 GR GR59993A patent/GR72494B/el unknown
- 1979-09-07 IT IT50202/79A patent/IT1120561B/it active
- 1979-09-07 AT AT0592679A patent/AT364813B/de not_active IP Right Cessation
- 1979-09-07 NO NO792901A patent/NO792901L/no unknown
- 1979-09-07 AU AU50686/79A patent/AU5068679A/en not_active Abandoned
- 1979-09-07 PT PT70151A patent/PT70151B/pt unknown
- 1979-09-07 GB GB7931218A patent/GB2030984B/en not_active Expired
- 1979-09-07 FR FR7922468A patent/FR2435462A1/fr active Pending
- 1979-09-07 JP JP11508979A patent/JPS5592350A/ja active Pending
- 1979-09-07 NZ NZ191505A patent/NZ191505A/xx unknown
- 1979-09-07 DK DK374879A patent/DK374879A/da not_active Application Discontinuation
- 1979-09-07 ES ES483985A patent/ES483985A1/es not_active Expired
- 1979-09-07 CA CA000335200A patent/CA1136622A/en not_active Expired
- 1979-09-07 BE BE0/197051A patent/BE878662A/fr unknown
- 1979-09-07 ZA ZA00794764A patent/ZA794764B/xx unknown
- 1979-09-07 FI FI792780A patent/FI792780A/fi not_active Application Discontinuation
- 1979-09-07 IL IL58200A patent/IL58200A/xx unknown
- 1979-09-07 SE SE7907432A patent/SE7907432L/xx not_active Application Discontinuation
- 1979-09-07 DE DE19792936287 patent/DE2936287A1/de not_active Withdrawn
- 1979-09-10 NL NL7906745A patent/NL7906745A/nl not_active Application Discontinuation
-
1980
- 1980-12-10 AT AT0600280A patent/AT370088B/de not_active IP Right Cessation
- 1980-12-10 AT AT0600180A patent/AT370087B/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ES483985A1 (es) | 1980-04-16 |
| DE2936287A1 (de) | 1980-03-20 |
| AT370087B (de) | 1983-02-25 |
| FI792780A (fi) | 1980-03-09 |
| SE7907432L (sv) | 1980-03-09 |
| FR2435462A1 (fr) | 1980-04-04 |
| GB2030984B (en) | 1983-07-27 |
| AU5068679A (en) | 1980-03-27 |
| IT7950202A0 (it) | 1979-09-07 |
| PT70151B (pt) | 1981-12-11 |
| NO792901L (no) | 1980-03-11 |
| GR72494B (it) | 1983-11-15 |
| NZ191505A (en) | 1982-03-30 |
| ATA600180A (de) | 1982-07-15 |
| IL58200A0 (en) | 1979-12-30 |
| JPS5592350A (en) | 1980-07-12 |
| PT70151A (en) | 1979-09-01 |
| ZA794764B (en) | 1981-04-29 |
| DK374879A (da) | 1980-03-09 |
| CA1136622A (en) | 1982-11-30 |
| US4217306A (en) | 1980-08-12 |
| IL58200A (en) | 1982-12-31 |
| GB2030984A (en) | 1980-04-16 |
| AT364813B (de) | 1981-11-25 |
| BE878662A (fr) | 1980-03-07 |
| NL7906745A (nl) | 1980-03-11 |
| AT370088B (de) | 1983-02-25 |
| ATA592679A (de) | 1981-04-15 |
| ATA600280A (de) | 1982-07-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IT1116820B (it) | Derivati di moranolina con proprieta'farmacologiche | |
| IT1121238B (it) | Derivati di amminotiazoli ad azione farmaceutica | |
| IT1209143B (it) | Derivati di 7-osso-4-tia-1-aza-biciclo-[3,2,0]eptano | |
| IT8047580A0 (it) | Derivati di 1,2-diidro-2-osso-4-fe nil-3-chinolin-carbonitrile dotati di proprieta' anti-infiammatorie | |
| FR2348926A1 (fr) | Nouveaux derives de l'adenine | |
| FI790922A (fi) | 2,6-dialkoxibenzamider mellanprodukter farmaceutiska kompositioner och foerfarande foer behandling av psykotiska sjukdomar | |
| IT1115217B (it) | Derivati di-o-n-alchilici della glicerina come stimolanti di immunita' | |
| IT1120561B (it) | Derivati alfa-aril-alfa alfa-bis omega-ammino bisostituiti alchilacetammidici ditati di proprieta' farmacologiche antiaritmia | |
| IT7950309A0 (it) | Composti furanici sostituiti dotati di proprieta' farmacologiche | |
| IT1121748B (it) | Composizioni con proprieta'deodoranti costituite prevalentemente da derivati cicloesilici di alcooli alifatici | |
| IT1164906B (it) | Derivati indolici dotati di proprieta' farmacologiche | |
| IT1122180B (it) | Derivati di 1-fenil-1-propanolo | |
| IT7949441A0 (it) | Derivati di arabino-furanosil-cito sina | |
| IT1116482B (it) | Procedimento per la produzione di p-fenilendiammine n-fenil-n'-sostituite asimmetriche | |
| IT7948802A0 (it) | Derivati di n-alchenilmoranolina aventi attivita' farmacologica | |
| TR19935A (tr) | Izotiouronyum fosfit'leri asih fungisid terkipler | |
| IT1162702B (it) | Derivati di 11-alcanoil-4"-isonitril-oleandomicina | |
| IT1094287B (it) | Derivati della 2-idrossimetil-pirazina aventi attivita' ipolipemizzante | |
| IT1085538B (it) | Derivati di i 125 immidazol-steroidi | |
| IT7950523A0 (it) | Derivati carbamoil-piperazinici dotati di attivita' farmacologica | |
| IT1113377B (it) | Derivati di n-ciano-azometini | |
| BE857512A (fr) | Nouveaux derives de l'imidazole | |
| MC1285A1 (fr) | Derives d'isoquinoleine | |
| IT1122310B (it) | Derivati dell'acido tio-propanoilamminico | |
| FI65428B (fi) | Foerfarande foer framstaellning av farmakologiskt vaerdefulla 2-fenylamino-imidazolin-(2) derivat |