SE7710873L - Nya 1h-pyrazolo(3,4-b)pyridiner - Google Patents
Nya 1h-pyrazolo(3,4-b)pyridinerInfo
- Publication number
- SE7710873L SE7710873L SE7710873A SE7710873A SE7710873L SE 7710873 L SE7710873 L SE 7710873L SE 7710873 A SE7710873 A SE 7710873A SE 7710873 A SE7710873 A SE 7710873A SE 7710873 L SE7710873 L SE 7710873L
- Authority
- SE
- Sweden
- Prior art keywords
- pyrazolo
- pyridines
- new
- benzyl
- methyl
- Prior art date
Links
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000001741 anti-phlogistic effect Effects 0.000 abstract 1
- 230000002785 anti-thrombosis Effects 0.000 abstract 1
- 229960004676 antithrombotic agent Drugs 0.000 abstract 1
- -1 di-substituted piperidino Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000004029 hydroxymethyl group Chemical group [H]OC([H])([H])* 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/84—Nitriles
- C07D213/85—Nitriles in position 3
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19762643753 DE2643753A1 (de) | 1976-09-29 | 1976-09-29 | Neue 1h-pyrazolo eckige klammer auf 3,4-b eckige klammer zu pyridine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE7710873L true SE7710873L (sv) | 1978-03-30 |
Family
ID=5989097
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7710873A SE7710873L (sv) | 1976-09-29 | 1977-09-28 | Nya 1h-pyrazolo(3,4-b)pyridiner |
Country Status (21)
| Country | Link |
|---|---|
| US (3) | US4182887A (cs) |
| JP (1) | JPS5344588A (cs) |
| AT (1) | AT359064B (cs) |
| AU (1) | AU513406B2 (cs) |
| BE (1) | BE859152A (cs) |
| DE (1) | DE2643753A1 (cs) |
| DK (1) | DK143183C (cs) |
| ES (1) | ES462700A1 (cs) |
| FI (1) | FI61899C (cs) |
| FR (1) | FR2366290A1 (cs) |
| GB (1) | GB1552730A (cs) |
| GR (1) | GR64049B (cs) |
| IE (1) | IE45700B1 (cs) |
| IL (1) | IL52997A (cs) |
| LU (1) | LU78179A1 (cs) |
| NL (1) | NL7710573A (cs) |
| NO (1) | NO147913C (cs) |
| NZ (1) | NZ185292A (cs) |
| PT (1) | PT67091B (cs) |
| SE (1) | SE7710873L (cs) |
| ZA (1) | ZA775784B (cs) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2643753A1 (de) * | 1976-09-29 | 1978-04-06 | Thomae Gmbh Dr K | Neue 1h-pyrazolo eckige klammer auf 3,4-b eckige klammer zu pyridine |
| AR037233A1 (es) | 2001-09-07 | 2004-11-03 | Euro Celtique Sa | Piridinas aril sustituidas, composiciones farmaceuticas y el uso de dichos compuestos para la elaboracion de un medicamento |
| AR036873A1 (es) * | 2001-09-07 | 2004-10-13 | Euro Celtique Sa | Piridinas aril sustituidas a, composiciones farmaceuticas y el uso de las mismas para la preparacion de un medicamento |
| WO2005007648A2 (en) * | 2003-07-16 | 2005-01-27 | Neurogen Corporation | Biaryl piperazinyl-pyridine analogues |
| EP1687004A4 (en) * | 2003-11-10 | 2009-04-08 | Synta Pharmaceuticals Corp | PYRIDINE COMPOUNDS |
| KR100881240B1 (ko) | 2004-07-06 | 2009-02-05 | 에프. 호프만-라 로슈 아게 | Nk-1 수용체 길항제의 합성에 있어서 중간체로서사용되는 카르복스아미드 피리딘 유도체의 제조 방법 |
| CA2572645C (en) * | 2004-07-06 | 2011-01-18 | F. Hoffmann-La Roche Ag | Process for preparing carboxamide derivatives used as intermediates in the synthesis of nk-1 receptor antagonists |
| MY145822A (en) * | 2004-08-13 | 2012-04-30 | Neurogen Corp | Substituted biaryl piperazinyl-pyridine analogues |
| CA2585934C (en) * | 2004-10-29 | 2013-09-10 | Abbott Laboratories | Novel pyrazolopyridine urea kinase inhibitors |
| DE102004061288A1 (de) * | 2004-12-14 | 2006-06-29 | Schering Ag | 3-Amino-Pyrazolo[3,4b]pyridine als Inhibitoren von Proteintyrosinkinasen, deren Herstellung und Verwendung als Arzneimittel |
| US7725056B2 (en) * | 2006-01-10 | 2010-05-25 | Ricoh Co., Ltd. | Triboelectric charging device and field assisted toner transporter |
| UA100684C2 (uk) | 2007-03-15 | 2013-01-25 | Новартіс Аг | Похідні бензилу та піридинілу як модулятори сигнального шляху hedgehog |
| US20100041663A1 (en) | 2008-07-18 | 2010-02-18 | Novartis Ag | Organic Compounds as Smo Inhibitors |
| CN102224152B (zh) | 2008-11-20 | 2014-05-21 | 健泰科生物技术公司 | 吡唑并吡啶pi3k抑制剂化合物及使用方法 |
| US8846673B2 (en) | 2009-08-11 | 2014-09-30 | Bristol-Myers Squibb Company | Azaindazoles as kinase inhibitors and use thereof |
| JP7322140B6 (ja) * | 2018-05-02 | 2024-02-21 | ジェイダブリュ ファーマシューティカル コーポレーション | 新規なヘテロサイクル誘導体 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2232038A1 (de) * | 1972-06-30 | 1974-01-10 | Hoechst Ag | 3-amino-1h-pyrazolo eckige klammer auf 3,4-b eckige klammer zu pyridine, ihre herstellung und verwendung |
| DE2643753A1 (de) * | 1976-09-29 | 1978-04-06 | Thomae Gmbh Dr K | Neue 1h-pyrazolo eckige klammer auf 3,4-b eckige klammer zu pyridine |
| US4048184A (en) * | 1976-11-15 | 1977-09-13 | E. R. Squibb & Sons, Inc. | 6-Phenyl-2H-pyrazolo[3,4-b]pyridines |
-
1976
- 1976-09-29 DE DE19762643753 patent/DE2643753A1/de not_active Withdrawn
-
1977
- 1977-09-07 FI FI772655A patent/FI61899C/fi not_active IP Right Cessation
- 1977-09-19 AT AT670077A patent/AT359064B/de not_active IP Right Cessation
- 1977-09-19 US US05/834,114 patent/US4182887A/en not_active Expired - Lifetime
- 1977-09-22 AU AU29037/77A patent/AU513406B2/en not_active Expired
- 1977-09-26 LU LU78179A patent/LU78179A1/xx unknown
- 1977-09-26 IL IL52997A patent/IL52997A/xx unknown
- 1977-09-27 GR GR54440A patent/GR64049B/el unknown
- 1977-09-28 NL NL7710573A patent/NL7710573A/xx not_active Application Discontinuation
- 1977-09-28 SE SE7710873A patent/SE7710873L/xx not_active Application Discontinuation
- 1977-09-28 ES ES462700A patent/ES462700A1/es not_active Expired
- 1977-09-28 ZA ZA00775784A patent/ZA775784B/xx unknown
- 1977-09-28 DK DK428477A patent/DK143183C/da active
- 1977-09-28 JP JP11657277A patent/JPS5344588A/ja active Pending
- 1977-09-28 NO NO773327A patent/NO147913C/no unknown
- 1977-09-28 PT PT67091A patent/PT67091B/pt unknown
- 1977-09-28 GB GB40364/77A patent/GB1552730A/en not_active Expired
- 1977-09-28 NZ NZ185292A patent/NZ185292A/xx unknown
- 1977-09-28 IE IE1988/77A patent/IE45700B1/en unknown
- 1977-09-28 BE BE181275A patent/BE859152A/xx unknown
- 1977-09-29 FR FR7729322A patent/FR2366290A1/fr active Granted
-
1979
- 1979-09-13 US US06/075,100 patent/US4260621A/en not_active Expired - Lifetime
- 1979-09-13 US US06/075,493 patent/US4224322A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| FI61899B (fi) | 1982-06-30 |
| NO147913C (no) | 1983-07-06 |
| IE45700B1 (en) | 1982-11-03 |
| FI772655A7 (fi) | 1978-03-30 |
| NO773327L (no) | 1978-03-30 |
| NZ185292A (en) | 1980-05-08 |
| PT67091B (de) | 1979-09-12 |
| ES462700A1 (es) | 1978-06-01 |
| LU78179A1 (cs) | 1978-11-03 |
| DK143183C (da) | 1981-11-16 |
| NL7710573A (nl) | 1978-03-31 |
| BE859152A (fr) | 1978-03-28 |
| ATA670077A (de) | 1980-03-15 |
| IL52997A0 (en) | 1977-11-30 |
| AU513406B2 (en) | 1980-11-27 |
| AT359064B (de) | 1980-10-27 |
| FI61899C (fi) | 1982-10-11 |
| FR2366290B1 (cs) | 1982-07-09 |
| GR64049B (en) | 1980-01-19 |
| DE2643753A1 (de) | 1978-04-06 |
| DK143183B (da) | 1981-07-13 |
| AU2903777A (en) | 1979-03-29 |
| IL52997A (en) | 1980-09-16 |
| NO147913B (no) | 1983-03-28 |
| PT67091A (de) | 1977-10-01 |
| IE45700L (en) | 1978-03-29 |
| US4224322A (en) | 1980-09-23 |
| ZA775784B (en) | 1979-06-27 |
| JPS5344588A (en) | 1978-04-21 |
| FR2366290A1 (fr) | 1978-04-28 |
| US4182887A (en) | 1980-01-08 |
| DK428477A (da) | 1978-03-30 |
| GB1552730A (en) | 1979-09-19 |
| US4260621A (en) | 1981-04-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NAV | Patent application has lapsed |
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