SE7701213L - WAY TO PRODUCE NEW TRIFENYL ALKENE DERIVATIVES - Google Patents

WAY TO PRODUCE NEW TRIFENYL ALKENE DERIVATIVES

Info

Publication number
SE7701213L
SE7701213L SE7701213A SE7701213A SE7701213L SE 7701213 L SE7701213 L SE 7701213L SE 7701213 A SE7701213 A SE 7701213A SE 7701213 A SE7701213 A SE 7701213A SE 7701213 L SE7701213 L SE 7701213L
Authority
SE
Sweden
Prior art keywords
trifenyl
way
produce new
alkene derivatives
derivatives
Prior art date
Application number
SE7701213A
Other languages
Swedish (sv)
Other versions
SE431324B (en
Inventor
T Horvath
G Abraham
G Schneider
L Toldy
O Feher
Szent H E
E Csanyi
Original Assignee
Egy Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egy Gyogyszervegyeszeti Gyar filed Critical Egy Gyogyszervegyeszeti Gyar
Publication of SE7701213L publication Critical patent/SE7701213L/en
Publication of SE431324B publication Critical patent/SE431324B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
    • C07C49/813—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen polycyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/35—Preparation of halogenated hydrocarbons by reactions not affecting the number of carbon or of halogen atoms in the reaction
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C25/00—Compounds containing at least one halogen atom bound to a six-membered aromatic ring
    • C07C25/24—Halogenated aromatic hydrocarbons with unsaturated side chains

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Novel triphenyl-alkene derivatives and process for preparing same The invention relates to novel triphenylalkene derivatives of the general formula I (I) wherein R denotes a C1-4 alkyl group and X stands for a halogen atom, with the restriction that when R denotes a methyl group, then X may denote only a halogen atom other than chlorine, and their geometrical isomers. Furthermore, the invention relates to a process for the production of these compounds. The compounds according to the invention can be used for the preparation of Tamoxifen, a known agent against ???illary ??ncer, and of related compounds. Furthermore, they possess a valuable biological activity.
SE7701213A 1976-02-05 1977-02-03 SET TO MAKE TRIPHENYL ALKENE DERIVATIVES SE431324B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU76GO00001328A HU171269B (en) 1976-02-05 1976-02-05 Process for preparing new triphenyl-alkene derivatives

Publications (2)

Publication Number Publication Date
SE7701213L true SE7701213L (en) 1977-08-06
SE431324B SE431324B (en) 1984-01-30

Family

ID=10996802

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7701213A SE431324B (en) 1976-02-05 1977-02-03 SET TO MAKE TRIPHENYL ALKENE DERIVATIVES

Country Status (11)

Country Link
JP (1) JPS52122352A (en)
AT (1) AT345804B (en)
CA (1) CA1087212A (en)
CH (1) CH624655A5 (en)
DE (1) DE2704690C2 (en)
HU (1) HU171269B (en)
NL (1) NL7701025A (en)
PL (1) PL105534B1 (en)
SE (1) SE431324B (en)
SU (1) SU856376A3 (en)
YU (1) YU39669B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0011372B1 (en) * 1978-11-07 1983-02-09 Imperial Chemical Industries Plc 1-acyloxyphenyl-1,2-diphenylalkene derivatives, processes for their manufacture and a pharmaceutical composition containing these derivatives
US5030764A (en) * 1986-05-23 1991-07-09 Hoffmann-La Roche Inc. Novel tetrahydronaphthalene and indane derivatives
ZW7487A1 (en) * 1986-05-23 1987-12-16 Hoffmann La Roche Tetrahydronaphthaline and indane derivatives
US5030765A (en) * 1986-05-23 1991-07-09 Hoffmann-La Roche Inc. Novel tetrahydronaphthalene and indane derivatives
AT388728B (en) * 1987-03-17 1989-08-25 Hoffmann La Roche NEW TETRAHYDRONAPHTHALINE AND INDANDERIVATIVES
GB9714310D0 (en) * 1997-07-07 1997-09-10 Smithkline Beecham Plc Process

Also Published As

Publication number Publication date
SU856376A3 (en) 1981-08-15
YU30977A (en) 1982-06-30
CA1087212A (en) 1980-10-07
NL7701025A (en) 1977-08-09
ATA59577A (en) 1978-02-15
PL105534B1 (en) 1979-10-31
JPS6149294B2 (en) 1986-10-29
SE431324B (en) 1984-01-30
DE2704690A1 (en) 1977-08-11
DE2704690C2 (en) 1987-01-29
YU39669B (en) 1985-03-20
CH624655A5 (en) 1981-08-14
HU171269B (en) 1977-12-28
JPS52122352A (en) 1977-10-14
AT345804B (en) 1978-10-10

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