ES471125A1 - 1-Substituted aminoindolines, process for their production and pharmaceutical compositions containing them. - Google Patents

1-Substituted aminoindolines, process for their production and pharmaceutical compositions containing them.

Info

Publication number
ES471125A1
ES471125A1 ES471125A ES471125A ES471125A1 ES 471125 A1 ES471125 A1 ES 471125A1 ES 471125 A ES471125 A ES 471125A ES 471125 A ES471125 A ES 471125A ES 471125 A1 ES471125 A1 ES 471125A1
Authority
ES
Spain
Prior art keywords
aminoindolines
substituted
production
pharmaceutical compositions
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES471125A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES471125A1 publication Critical patent/ES471125A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/08Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

The compounds of formula I, < CHEM > wherein R1 to R5 and n have various significances, are useful as vasoconstricting agents.
ES471125A 1977-06-28 1978-06-26 1-Substituted aminoindolines, process for their production and pharmaceutical compositions containing them. Expired ES471125A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH791577 1977-06-28

Publications (1)

Publication Number Publication Date
ES471125A1 true ES471125A1 (en) 1979-09-16

Family

ID=4332315

Family Applications (1)

Application Number Title Priority Date Filing Date
ES471125A Expired ES471125A1 (en) 1977-06-28 1978-06-26 1-Substituted aminoindolines, process for their production and pharmaceutical compositions containing them.

Country Status (13)

Country Link
EP (1) EP0000151B1 (en)
JP (1) JPS5412373A (en)
AU (1) AU3746878A (en)
CA (1) CA1094553A (en)
DE (1) DE2860709D1 (en)
DK (1) DK275278A (en)
ES (1) ES471125A1 (en)
FI (1) FI781947A (en)
IL (1) IL55005A (en)
IT (1) IT7850073A0 (en)
NZ (1) NZ187675A (en)
PT (1) PT68217A (en)
ZA (1) ZA783708B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT7950924A0 (en) * 1978-12-13 1979-11-28 Sandoz Ag DERIVATIVES OF 1-AMINOINDOLIN THEIR PREPARATION AND APPLICATION AS MEDICINAL PRODUCTS
DE3133302A1 (en) * 1981-08-22 1983-03-03 Beiersdorf Ag, 2000 Hamburg ISOINDOLIN-2-YL-AMINO-IMIDAZOLINE AND ISOINDOLIN-2-YL-GUANIDINE, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS A MEDICINAL PRODUCT
DE3343801A1 (en) * 1983-12-03 1985-06-13 Dr. Karl Thomae Gmbh, 7950 Biberach NEW INDOLDER DERIVATIVES, MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS AND METHOD FOR THE PRODUCTION THEREOF
CA3214757A1 (en) 2021-04-08 2022-10-13 Andreas Loew Multifuntional molecules binding to tcr and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH529702A (en) * 1970-07-06 1972-10-31 Sandoz Ag Optically active benz(c,d)indole derivs - with vasoconstrictive and cns - smoothing activity
GB1408362A (en) * 1973-05-25 1975-10-01 Lepetit Spa 2-pyrrol-1-yl amino 4,5-dihydro-1-h-imidazole derivatives

Also Published As

Publication number Publication date
IL55005A0 (en) 1978-08-31
EP0000151B1 (en) 1981-05-20
ZA783708B (en) 1980-02-27
DK275278A (en) 1978-12-29
PT68217A (en) 1978-07-01
EP0000151A1 (en) 1979-01-10
NZ187675A (en) 1981-02-11
JPS5412373A (en) 1979-01-30
IL55005A (en) 1981-12-31
FI781947A (en) 1978-12-29
AU3746878A (en) 1980-01-03
CA1094553A (en) 1981-01-27
IT7850073A0 (en) 1978-06-28
DE2860709D1 (en) 1981-08-27

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