SE7510595L - WAY TO PRODUCE IMIDAZOL DERIVATIVES - Google Patents

WAY TO PRODUCE IMIDAZOL DERIVATIVES

Info

Publication number
SE7510595L
SE7510595L SE7510595A SE7510595A SE7510595L SE 7510595 L SE7510595 L SE 7510595L SE 7510595 A SE7510595 A SE 7510595A SE 7510595 A SE7510595 A SE 7510595A SE 7510595 L SE7510595 L SE 7510595L
Authority
SE
Sweden
Prior art keywords
formula
compound
compounds
reacted
image
Prior art date
Application number
SE7510595A
Other languages
Swedish (sv)
Other versions
SE428471B (en
Inventor
K A M Walker
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of SE7510595L publication Critical patent/SE7510595L/en
Publication of SE428471B publication Critical patent/SE428471B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Abstract

The novel imidazole derivatives correspond to the formula <IMAGE> in which R, R<1> and p have the meanings given in Patent Claim 1, and m is 0, 1 or 2. To prepare the compounds of formula I, wherein m is 0, a compound of formula: <IMAGE> is reacted with a compound of formula RSH. X denotes a group which can be split off. To prepare compounds of formula I, wherein m represents 1 or 2, a) a compound of formula II is reacted with a compound of formula RSH and b) the resulting compound of formula I, wherein m represents O, is oxidised. m conforms to the conditions specified for q in Patent Claim 7. The compounds of formula I are obtained in the form of their free base or of its acid addition salts. These can be converted into one another. An agent for inhibiting the growth of fungi or bacteria in plants or in agricultural or industrial products contains a compound of formula I as active ingredient, mixed with a carrier. The compounds of formula I possess, quite generally, an antifungal and antibacterial action and can also be used for pharmaceutical purposes.
SE7510595A 1974-09-23 1975-09-22 SET TO MAKE IMIDAZOLD DERIVATIVES SE428471B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50838474A 1974-09-23 1974-09-23
US59362075A 1975-07-07 1975-07-07

Publications (2)

Publication Number Publication Date
SE7510595L true SE7510595L (en) 1976-03-24
SE428471B SE428471B (en) 1983-07-04

Family

ID=27056177

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7510595A SE428471B (en) 1974-09-23 1975-09-22 SET TO MAKE IMIDAZOLD DERIVATIVES

Country Status (19)

Country Link
JP (1) JPS5910344B2 (en)
AR (1) AR224222A1 (en)
AU (1) AU496881B2 (en)
CA (1) CA1064040A (en)
CH (1) CH623813A5 (en)
DE (1) DE2541833A1 (en)
DK (1) DK155283C (en)
FI (1) FI64583C (en)
FR (1) FR2285126A1 (en)
GB (1) GB1485719A (en)
HK (1) HK8380A (en)
IE (1) IE43267B1 (en)
IL (1) IL47885A (en)
MX (1) MX4832E (en)
MY (1) MY8000270A (en)
NL (1) NL174462C (en)
NO (1) NO144345C (en)
SE (1) SE428471B (en)
YU (3) YU39746B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA755100B (en) * 1974-09-23 1977-03-30 Syntex Inc 1-(b-(r-thio) phenethyl) imidazoles and derivatives thereof
EP0013786B1 (en) * 1979-01-22 1982-10-06 Syntex (U.S.A.) Inc. Imidazole derivatives, pharmaceutical compositions containing them and their preparation
JPS63156228U (en) * 1987-04-01 1988-10-13
DE3939525A1 (en) * 1989-11-30 1991-06-06 Hoechst Ag ARYL-ALKYL-AZOLES SUBSTITUTED WITH MULTIPLE UNSATURATED REMAINS, METHOD FOR THEIR PRODUCTION AND THEIR USE
IT1303672B1 (en) * 1998-07-28 2001-02-23 Nicox Sa NITRATED SALTS OF DRUGS ACTIVE IN BONE DISORDERS
CN116063234B (en) * 2022-12-29 2023-11-24 山东京卫制药有限公司 Preparation method of sulconazole nitrate

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU557755A3 (en) * 1968-08-19 1977-05-05 Янссен Фармасьютика Н.В. (Фирма) Method for preparing imidazole derivatives
US3658813A (en) * 1970-01-13 1972-04-25 Janssen Pharmaceutica Nv 1-(beta-aryl-beta-(r-oxy)-ethyl)-imidazoles
DE2041771C3 (en) * 1970-08-22 1979-07-26 Bayer Ag, 5090 Leverkusen derivatives
SE364275B (en) * 1971-06-17 1974-02-18 Janssen Pharmaceutica Nv
DE2242454A1 (en) * 1972-08-29 1974-03-07 Bayer Ag 1-AETHYL-IMIDAZOLE, METHOD FOR MANUFACTURING IT AND ITS USE AS A MEDICINAL PRODUCT

Also Published As

Publication number Publication date
AU8408175A (en) 1977-02-24
SE428471B (en) 1983-07-04
YU226981A (en) 1982-02-28
DK155283B (en) 1989-03-20
DE2541833C2 (en) 1989-09-14
CH623813A5 (en) 1981-06-30
YU39746B (en) 1985-04-30
FI64583B (en) 1983-08-31
AU496881B2 (en) 1978-11-09
NL7510224A (en) 1976-03-25
FI64583C (en) 1983-12-12
NO144345B (en) 1981-05-04
DK155283C (en) 1989-07-24
FR2285126B1 (en) 1979-09-14
MX4832E (en) 1982-10-26
FI752614A (en) 1976-03-24
YU224475A (en) 1982-02-28
NO753048L (en) 1976-03-24
IE43267L (en) 1976-03-23
AR224222A1 (en) 1981-11-13
IL47885A0 (en) 1975-11-25
IE43267B1 (en) 1981-01-28
NO144345C (en) 1981-08-12
YU227081A (en) 1982-02-28
DE2541833A1 (en) 1976-04-01
JPS5157828A (en) 1976-05-20
CA1064040A (en) 1979-10-09
JPS5910344B2 (en) 1984-03-08
NL174462B (en) 1984-01-16
MY8000270A (en) 1980-12-31
IL47885A (en) 1979-01-31
FR2285126A1 (en) 1976-04-16
NL174462C (en) 1984-06-18
HK8380A (en) 1980-03-14
DK427075A (en) 1976-03-24
GB1485719A (en) 1977-09-14

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