SE519566C2 - Förfarande för behandling av implantat genom beläggning med kalciumfosfat och bentillväxtstimulerande medel - Google Patents
Förfarande för behandling av implantat genom beläggning med kalciumfosfat och bentillväxtstimulerande medelInfo
- Publication number
- SE519566C2 SE519566C2 SE0102389A SE0102389A SE519566C2 SE 519566 C2 SE519566 C2 SE 519566C2 SE 0102389 A SE0102389 A SE 0102389A SE 0102389 A SE0102389 A SE 0102389A SE 519566 C2 SE519566 C2 SE 519566C2
- Authority
- SE
- Sweden
- Prior art keywords
- layer
- cap
- implant
- bone growth
- calcium phosphate
- Prior art date
Links
- 239000007943 implant Substances 0.000 title claims abstract description 56
- 238000000034 method Methods 0.000 title claims abstract description 15
- 230000008468 bone growth Effects 0.000 title claims description 21
- 238000000576 coating method Methods 0.000 title claims description 21
- 229910000389 calcium phosphate Inorganic materials 0.000 title claims description 12
- 239000001506 calcium phosphate Substances 0.000 title claims description 12
- 235000011010 calcium phosphates Nutrition 0.000 title claims description 12
- 239000011248 coating agent Substances 0.000 title claims description 10
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 title claims description 4
- 239000000021 stimulant Substances 0.000 title 1
- 239000011148 porous material Substances 0.000 claims abstract description 25
- 239000002269 analeptic agent Substances 0.000 claims abstract description 13
- 239000010410 layer Substances 0.000 claims description 96
- 239000000126 substance Substances 0.000 claims description 22
- 238000002425 crystallisation Methods 0.000 claims description 13
- 230000008025 crystallization Effects 0.000 claims description 13
- -1 calcium phosphate compound Chemical class 0.000 claims description 12
- 238000011282 treatment Methods 0.000 claims description 10
- 238000010438 heat treatment Methods 0.000 claims description 5
- 239000000463 material Substances 0.000 claims description 5
- 230000004936 stimulating effect Effects 0.000 claims description 5
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 claims description 4
- 239000002344 surface layer Substances 0.000 claims description 4
- 229910052719 titanium Inorganic materials 0.000 claims description 4
- 239000010936 titanium Substances 0.000 claims description 4
- 230000012010 growth Effects 0.000 claims description 3
- 230000003647 oxidation Effects 0.000 claims description 3
- 238000007254 oxidation reaction Methods 0.000 claims description 3
- 238000004873 anchoring Methods 0.000 claims description 2
- 238000010276 construction Methods 0.000 claims description 2
- 230000009977 dual effect Effects 0.000 claims 1
- 230000014759 maintenance of location Effects 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 description 6
- 238000004519 manufacturing process Methods 0.000 description 6
- 238000011161 development Methods 0.000 description 3
- 230000018109 developmental process Effects 0.000 description 3
- 239000003792 electrolyte Substances 0.000 description 2
- 238000001755 magnetron sputter deposition Methods 0.000 description 2
- 238000004544 sputter deposition Methods 0.000 description 2
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 238000009388 chemical precipitation Methods 0.000 description 1
- 238000007598 dipping method Methods 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000002848 electrochemical method Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000005530 etching Methods 0.000 description 1
- 238000005755 formation reaction Methods 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 238000003801 milling Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000005498 polishing Methods 0.000 description 1
- 238000001552 radio frequency sputter deposition Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 230000003746 surface roughness Effects 0.000 description 1
- OGIDPMRJRNCKJF-UHFFFAOYSA-N titanium oxide Inorganic materials [Ti]=O OGIDPMRJRNCKJF-UHFFFAOYSA-N 0.000 description 1
- 238000007514 turning Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical class O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
- A61C8/0012—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the material or composition, e.g. ceramics, surface layer, metal alloy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
- A61C8/0012—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the material or composition, e.g. ceramics, surface layer, metal alloy
- A61C8/0013—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the material or composition, e.g. ceramics, surface layer, metal alloy with a surface layer, coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/30—Inorganic materials
- A61L27/32—Phosphorus-containing materials, e.g. apatite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
- A61L2300/112—Phosphorus-containing compounds, e.g. phosphates, phosphonates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/606—Coatings
- A61L2300/608—Coatings having two or more layers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Transplantation (AREA)
- Dentistry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Ceramic Engineering (AREA)
- Dispersion Chemistry (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Prostheses (AREA)
- Materials For Medical Uses (AREA)
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0102389A SE519566C2 (sv) | 2001-07-04 | 2001-07-04 | Förfarande för behandling av implantat genom beläggning med kalciumfosfat och bentillväxtstimulerande medel |
| US10/482,737 US8100985B2 (en) | 2001-07-04 | 2002-06-26 | Method for treating an implant, and such an implant |
| AT02744042T ATE526898T1 (de) | 2001-07-04 | 2002-06-26 | Verfahren zur behandlung eines implantats und ein solches implantat |
| PCT/SE2002/001255 WO2003003937A1 (en) | 2001-07-04 | 2002-06-26 | Method for treating an implant, and such an implant |
| EP02744042A EP1406552B1 (de) | 2001-07-04 | 2002-06-26 | Verfahren zur behandlung eines implantats und ein solches implantat |
| ES02744042T ES2371337T3 (es) | 2001-07-04 | 2002-06-26 | Método para tratar un implante, y dicho implante. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0102389A SE519566C2 (sv) | 2001-07-04 | 2001-07-04 | Förfarande för behandling av implantat genom beläggning med kalciumfosfat och bentillväxtstimulerande medel |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| SE0102389D0 SE0102389D0 (sv) | 2001-07-04 |
| SE0102389L SE0102389L (sv) | 2003-01-05 |
| SE519566C2 true SE519566C2 (sv) | 2003-03-11 |
Family
ID=20284730
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE0102389A SE519566C2 (sv) | 2001-07-04 | 2001-07-04 | Förfarande för behandling av implantat genom beläggning med kalciumfosfat och bentillväxtstimulerande medel |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US8100985B2 (de) |
| EP (1) | EP1406552B1 (de) |
| AT (1) | ATE526898T1 (de) |
| ES (1) | ES2371337T3 (de) |
| SE (1) | SE519566C2 (de) |
| WO (1) | WO2003003937A1 (de) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003055405A1 (en) | 2001-12-21 | 2003-07-10 | Nobel Biocare Ab (Publ) | Method for producing a surface structure on an implant, and such an implant |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2466947C (en) | 2001-11-19 | 2012-05-22 | Scil Technology Gmbh | A homogeneously coated device having osteoinductive and osteoconductive properties |
| GB0208642D0 (en) * | 2002-04-16 | 2002-05-22 | Accentus Plc | Metal implants |
| ES2260685T3 (es) | 2002-09-10 | 2006-11-01 | Scil Technology Gmbh | Implante metalico recubierto, a una concentracion de oxigeno reducida, con proteina osteoinductora. |
| SE526745C2 (sv) * | 2003-04-17 | 2005-11-01 | Nobel Biocare Ab | Fixtur för förankring i käkben |
| SE526749C2 (sv) * | 2003-12-11 | 2005-11-01 | Nobel Biocare Ab | Anordning vid dentalt implantat samt förfarande för dess framställning |
| GB0405680D0 (en) * | 2004-03-13 | 2004-04-21 | Accentus Plc | Metal implants |
| EP2316499B1 (de) * | 2006-06-12 | 2013-05-01 | Accentus Medical PLC | Metallimplantate |
| JP5535647B2 (ja) * | 2007-01-15 | 2014-07-02 | アクセンタス ピーエルシー | 金属インプラント |
| EP1961433A1 (de) * | 2007-02-20 | 2008-08-27 | National University of Ireland Galway | Poröse Substrate zur Implantation |
| AU2008306596B2 (en) | 2007-10-03 | 2013-04-04 | Accentus Plc | Method of manufacturing metal with biocidal properties |
| US9539097B2 (en) * | 2007-11-08 | 2017-01-10 | Linares Medical Devices, Llc | Hip and knee joint assemblies incorporating debris collection architecture between the ball and seat interface |
| US8828088B2 (en) * | 2007-11-08 | 2014-09-09 | Linares Medical Devices, Llc | Joint assembly incorporating undercut surface design to entrap accumulating wear debris from plastic joint assembly |
| DE102011001401A1 (de) * | 2010-12-20 | 2012-06-21 | Frank-Peter Spahn | Crestales Implantat und Verfahren zu dessen Bearbeitung |
| DE102011001403A1 (de) * | 2011-03-18 | 2012-09-20 | Frank-Peter Spahn | Zahnimplantat und Verfahren zur Herstellung oder zur Bearbeitung eines Zahnimplantats |
| BR112014000245B1 (pt) | 2011-07-06 | 2020-10-13 | Nobel Biocare Services Ag | parafuso e chave de parafuso |
| EA022035B1 (ru) * | 2012-08-21 | 2015-10-30 | Федеральное Государственное Бюджетное Образовательное Учреждение Высшего Профессионального Образования "Национальный Исследовательский Томский Политехнический Университет" (Фгбоу Впо Ни Тпу) | Способ получения гибридного покрытия на металлических имплантатах |
| GB2509739A (en) | 2013-01-11 | 2014-07-16 | Nobel Biocare Services Ag | Dental drill bit with spherical head and helical fluting |
| FR3010302B1 (fr) * | 2013-09-06 | 2020-10-23 | Robert Fromental | Procede de fabrication d'un implant dentaire comportant une couche de materiau amorphe et implant dentaire obtenu selon ledit procede |
| GB2523828A (en) | 2014-03-07 | 2015-09-09 | Nobel Biocare Services Ag | Dental implant |
| GB2523827A (en) | 2014-03-07 | 2015-09-09 | Nobel Biocare Services Ag | Dental implant |
| EP3034033A1 (de) | 2014-12-16 | 2016-06-22 | Nobel Biocare Services AG | Zahnimplantat |
| US10893944B2 (en) | 2017-03-30 | 2021-01-19 | Biomet Manufacturing, Llc | Methods of modifying the porous surface of implants |
| EP3880116B1 (de) | 2018-11-12 | 2024-01-10 | Nobel Biocare Services AG | Zahnimplantat, komponente für dentale anwendungen, implantatsystem für dentale anwendungen |
| RU2745726C1 (ru) * | 2020-05-29 | 2021-03-31 | Общество с ограниченной ответственностью "Научно-производственная компания "СИНТЕЛ" | Способ получения антибактериального кальцийфосфатного покрытия на ортопедическом имплантате, имеющем форму тела вращения и оснастка для его осуществления (варианты) |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5611347A (en) * | 1989-07-25 | 1997-03-18 | Smith & Nephew, Inc. | Zirconium oxide and zirconium nitride coated percutaneous devices |
| US5947893A (en) * | 1994-04-27 | 1999-09-07 | Board Of Regents, The University Of Texas System | Method of making a porous prothesis with biodegradable coatings |
| ATE462368T1 (de) * | 1994-11-30 | 2010-04-15 | Biomet 3I Llc | Vorbereitung einer implantatoberfläche |
| AU734691B2 (en) * | 1996-10-16 | 2001-06-21 | Life Science Enterprises, Inc. | Bioceramic compositions |
| DK0968011T3 (da) * | 1997-03-27 | 2004-12-20 | Smith & Nephew Inc | Fremgangsmåde til overfladeoxidation af zirkoniumlegeringer og fremstillet produkt |
| SE513481C2 (sv) * | 1997-05-16 | 2000-09-18 | Nobel Biocare Ab | Implantatelement utfört av titan med en titanoxidyta modifierad med eloxidering |
| US6214049B1 (en) * | 1999-01-14 | 2001-04-10 | Comfort Biomedical, Inc. | Method and apparatus for augmentating osteointegration of prosthetic implant devices |
| US5980566A (en) * | 1998-04-11 | 1999-11-09 | Alt; Eckhard | Vascular and endoluminal stents with iridium oxide coating |
| JP2000093503A (ja) * | 1998-09-15 | 2000-04-04 | Isotis Bv | 医療用インプラントをコ―トする方法 |
| SE514323C2 (sv) | 1999-05-31 | 2001-02-12 | Nobel Biocare Ab | Implantat samt förfarande och användning vid implantat |
| SE515695C2 (sv) | 1999-05-31 | 2001-09-24 | Nobel Biocare Ab | Implantat med beläggning av bentillväxtstimulerande substans för applicering i ben och förfarande vid sådant implantat |
| SE514202C2 (sv) | 1999-05-31 | 2001-01-22 | Nobel Biocare Ab | På implantat till ben- eller vävnadsstruktur anordnat skikt samt sådant implantat och förfarande för applicering av skiktet |
| US6517888B1 (en) * | 2000-11-28 | 2003-02-11 | Scimed Life Systems, Inc. | Method for manufacturing a medical device having a coated portion by laser ablation |
| DK1372749T3 (da) | 2001-04-02 | 2004-12-20 | Stratec Medical Ag | Bioaktivt overfladelag, især til medicinske implantater og proteser |
| US6527938B2 (en) * | 2001-06-21 | 2003-03-04 | Syntheon, Llc | Method for microporous surface modification of implantable metallic medical articles |
| US20040002766A1 (en) * | 2002-06-27 | 2004-01-01 | Gordon Hunter | Prosthetic devices having diffusion-hardened surfaces and bioceramic coatings |
-
2001
- 2001-07-04 SE SE0102389A patent/SE519566C2/sv not_active IP Right Cessation
-
2002
- 2002-06-26 ES ES02744042T patent/ES2371337T3/es not_active Expired - Lifetime
- 2002-06-26 AT AT02744042T patent/ATE526898T1/de not_active IP Right Cessation
- 2002-06-26 WO PCT/SE2002/001255 patent/WO2003003937A1/en not_active Ceased
- 2002-06-26 US US10/482,737 patent/US8100985B2/en not_active Expired - Fee Related
- 2002-06-26 EP EP02744042A patent/EP1406552B1/de not_active Expired - Lifetime
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003055405A1 (en) | 2001-12-21 | 2003-07-10 | Nobel Biocare Ab (Publ) | Method for producing a surface structure on an implant, and such an implant |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1406552A1 (de) | 2004-04-14 |
| SE0102389D0 (sv) | 2001-07-04 |
| EP1406552B1 (de) | 2011-10-05 |
| US8100985B2 (en) | 2012-01-24 |
| ATE526898T1 (de) | 2011-10-15 |
| WO2003003937A1 (en) | 2003-01-16 |
| US20050177248A1 (en) | 2005-08-11 |
| SE0102389L (sv) | 2003-01-05 |
| ES2371337T3 (es) | 2011-12-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NUG | Patent has lapsed |