SE504507C2 - Sätt att bestämma bindningsegenskaper hos ligander med låg molekylvikt - Google Patents

Sätt att bestämma bindningsegenskaper hos ligander med låg molekylvikt

Info

Publication number
SE504507C2
SE504507C2 SE9301755A SE9301755A SE504507C2 SE 504507 C2 SE504507 C2 SE 504507C2 SE 9301755 A SE9301755 A SE 9301755A SE 9301755 A SE9301755 A SE 9301755A SE 504507 C2 SE504507 C2 SE 504507C2
Authority
SE
Sweden
Prior art keywords
molecular weight
response
ligand
low molecular
affinity
Prior art date
Application number
SE9301755A
Other languages
English (en)
Swedish (sv)
Other versions
SE9301755D0 (sv
SE9301755L (sv
Inventor
Robert Karlsson
Original Assignee
Pharmacia Biosensor Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Biosensor Ab filed Critical Pharmacia Biosensor Ab
Priority to SE9301755A priority Critical patent/SE504507C2/sv
Publication of SE9301755D0 publication Critical patent/SE9301755D0/xx
Priority to JP7500537A priority patent/JPH09504859A/ja
Priority to US08/553,413 priority patent/US5753518A/en
Priority to PCT/SE1994/000480 priority patent/WO1994028416A1/en
Priority to DE69426155T priority patent/DE69426155T2/de
Priority to EP94917233A priority patent/EP0700519B1/en
Priority to AT94917233T priority patent/ATE197095T1/de
Publication of SE9301755L publication Critical patent/SE9301755L/xx
Publication of SE504507C2 publication Critical patent/SE504507C2/sv

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/808—Optical sensing apparatus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/805—Optical property
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/806—Electrical property or magnetic property

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SE9301755A 1993-05-24 1993-05-24 Sätt att bestämma bindningsegenskaper hos ligander med låg molekylvikt SE504507C2 (sv)

Priority Applications (7)

Application Number Priority Date Filing Date Title
SE9301755A SE504507C2 (sv) 1993-05-24 1993-05-24 Sätt att bestämma bindningsegenskaper hos ligander med låg molekylvikt
JP7500537A JPH09504859A (ja) 1993-05-24 1994-05-24 親和性及び反応速度特性の決定方法
US08/553,413 US5753518A (en) 1993-05-24 1994-05-24 Method of determining affinity and kinetic properties
PCT/SE1994/000480 WO1994028416A1 (en) 1993-05-24 1994-05-24 A method of determining affinity and kinetic properties
DE69426155T DE69426155T2 (de) 1993-05-24 1994-05-24 Verfahren zur bestimmung der affinität und der kinetischen eigenschaften
EP94917233A EP0700519B1 (en) 1993-05-24 1994-05-24 A method of determining affinity and kinetic properties
AT94917233T ATE197095T1 (de) 1993-05-24 1994-05-24 Verfahren zur bestimmung der affinität und der kinetischen eigenschaften

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9301755A SE504507C2 (sv) 1993-05-24 1993-05-24 Sätt att bestämma bindningsegenskaper hos ligander med låg molekylvikt

Publications (3)

Publication Number Publication Date
SE9301755D0 SE9301755D0 (sv) 1993-05-24
SE9301755L SE9301755L (sv) 1995-01-16
SE504507C2 true SE504507C2 (sv) 1997-02-24

Family

ID=20390025

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9301755A SE504507C2 (sv) 1993-05-24 1993-05-24 Sätt att bestämma bindningsegenskaper hos ligander med låg molekylvikt

Country Status (7)

Country Link
US (1) US5753518A (ja)
EP (1) EP0700519B1 (ja)
JP (1) JPH09504859A (ja)
AT (1) ATE197095T1 (ja)
DE (1) DE69426155T2 (ja)
SE (1) SE504507C2 (ja)
WO (1) WO1994028416A1 (ja)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9609653D0 (en) * 1996-05-09 1996-07-10 Applied Research Ars Holding N Method of assay
SE9604575D0 (sv) * 1996-12-12 1996-12-12 Biacore Ab Method and system for analyte determination
EP1204842A4 (en) * 1999-08-19 2003-04-02 Univ California APPARATUS AND METHOD FOR THE VISUAL IDENTIFICATION OF MICROFORCES BY MEANS OF A RANGE OF BOOM BLOCKS
EP1296140A4 (en) * 2000-06-27 2005-06-29 Chugai Pharmaceutical Co Ltd METHOD OF MEASURING THE BINDING ACTIVITY OF LIGANDS WITH LIGANDING BINDING PROTEINS
US6833920B2 (en) 2000-07-11 2004-12-21 Maven Technologies Llc Apparatus and method for imaging
US20020093654A1 (en) * 2000-07-11 2002-07-18 Lieberman Robert A. Apparatus and method for imaging
US6594011B1 (en) 2000-07-11 2003-07-15 Maven Technologies, Llc Imaging apparatus and method
US7193711B2 (en) * 2000-07-11 2007-03-20 Maven Technologies, Llc Imaging method and apparatus
US7518724B2 (en) * 2000-07-11 2009-04-14 Maven Technologies Image acquisition, processing, and display
US7023547B2 (en) * 2000-07-11 2006-04-04 Maven Technologies, Llc Apparatus including a biochip for imaging of biological samples and method
US7126688B2 (en) * 2000-07-11 2006-10-24 Maven Technologies, Llc Microarray scanning
US6887667B2 (en) * 2000-12-28 2005-05-03 Alfred E. Mann Institute For Biomedical Engineering At The University Of Southern California Method and apparatus to identify small variations of biomolecules
US20030154149A1 (en) * 2002-02-13 2003-08-14 Dilip Gajendragadkar System and method of creating and executing a restricted stock sale plan
DE60323150D1 (de) * 2002-12-02 2008-10-02 Ge Healthcare Bio Sciences Ab Verfahren zur bestimmung von ortsspezifizität und kit dafür
SE0203548D0 (sv) 2002-12-02 2002-12-02 Biacore Ab Method of determining site-specificity and kit therefor
US7373255B2 (en) * 2003-06-06 2008-05-13 Biacore Ab Method and system for determination of molecular interaction parameters
AU2004274843A1 (en) * 2003-09-24 2005-03-31 Ge Healthcare Bio-Sciences Ab Method and system for molecular interaction analysis
WO2005036174A1 (ja) * 2003-10-15 2005-04-21 Reverse Proteomics Research Institute Co., Ltd. リガンド特異性の検定方法
EP1584914A1 (en) * 2004-04-08 2005-10-12 Sony Deutschland GmbH A method of detecting a hybrid, formed of at least two species, on a substrate using ellipsometry
SE0401633D0 (sv) * 2004-06-24 2004-06-24 Biacore Ab Method for detecting molecular surface interactions
EP1766398B1 (en) * 2004-06-24 2011-01-05 GE Healthcare Bio-Sciences AB Method for detecting molecular surface interactions
JP4332478B2 (ja) * 2004-08-17 2009-09-16 富士フイルム株式会社 表面プラズモン共鳴分析における反応速度係数の測定方法
JP4053526B2 (ja) * 2004-08-17 2008-02-27 富士フイルム株式会社 表面プラズモン共鳴分析における離脱速度係数の測定方法
US7300631B2 (en) 2005-05-02 2007-11-27 Bioscale, Inc. Method and apparatus for detection of analyte using a flexural plate wave device and magnetic particles
US7648844B2 (en) * 2005-05-02 2010-01-19 Bioscale, Inc. Method and apparatus for detection of analyte using an acoustic device
US7611908B2 (en) * 2005-05-02 2009-11-03 Bioscale, Inc. Method and apparatus for therapeutic drug monitoring using an acoustic device
US7749445B2 (en) * 2005-05-02 2010-07-06 Bioscale, Inc. Method and apparatus for analyzing bioprocess fluids
EP1893978A4 (en) * 2005-06-13 2020-06-17 GE Healthcare Bio-Sciences AB AFFINITY ANALYSIS METHOD AND SYSTEM
US20100261288A1 (en) 2005-06-13 2010-10-14 Fortebio, Inc. Tip tray assembly for optical sensors
US8227261B2 (en) * 2005-11-23 2012-07-24 Bioscale, Inc. Methods and apparatus for assay measurements
EP1790984B1 (en) 2005-11-25 2013-08-28 FUJIFILM Corporation A method for producing a biosensor having a covalently bound thin polymeric coat
JP2007163284A (ja) * 2005-12-13 2007-06-28 Fujifilm Corp スクリーニング方法、スクリーニングプログラム及びスクリーニング装置
US20070161042A1 (en) * 2006-01-11 2007-07-12 Fortebio, Inc. Methods for characterizing molecular interactions
WO2008033535A2 (en) * 2006-09-14 2008-03-20 Fortebio, Inc. Amine-reactive biosensor
US7867783B2 (en) 2007-02-22 2011-01-11 Maven Technologies, Llc Apparatus and method for performing ligand binding assays on microarrays in multiwell plates
US7863037B1 (en) 2007-04-04 2011-01-04 Maven Technologies, Llc Ligand binding assays on microarrays in closed multiwell plates
US20090041633A1 (en) * 2007-05-14 2009-02-12 Dultz Shane C Apparatus and method for performing ligand binding assays on microarrays in multiwell plates
US7799558B1 (en) 2007-05-22 2010-09-21 Dultz Shane C Ligand binding assays on microarrays in closed multiwell plates
US8354280B2 (en) 2007-09-06 2013-01-15 Bioscale, Inc. Reusable detection surfaces and methods of using same
US7981664B1 (en) 2008-05-22 2011-07-19 Maven Technologies, Llc Apparatus and method for performing ligand binding assays on microarrays in multiwell plates
US8039270B2 (en) * 2008-05-22 2011-10-18 Maven Technologies, Llc Apparatus and method for performing ligand binding assays on microarrays in multiwell plates
US8355133B2 (en) * 2009-12-30 2013-01-15 Maven Technologies, Llc Biological testing with sawtooth-shaped prisms
US9990464B1 (en) 2012-10-09 2018-06-05 Pall Corporation Label-free biomolecular interaction analysis using a rapid analyte dispersion injection method

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL85137A (en) * 1987-01-21 1992-02-16 Ares Serono Res & Dev Ltd Method of assaying for a ligand using surface plasmon resonance effect
SE8804074D0 (sv) * 1988-11-10 1988-11-10 Pharmacia Ab Sensorenhet och dess anvaendning i biosensorsystem
SE8902043L (sv) * 1988-11-10 1990-05-11 Pharmacia Ab Foerfarande foer karakterisering av makromolekyler

Also Published As

Publication number Publication date
DE69426155D1 (de) 2000-11-23
EP0700519B1 (en) 2000-10-18
EP0700519A1 (en) 1996-03-13
SE9301755D0 (sv) 1993-05-24
ATE197095T1 (de) 2000-11-15
DE69426155T2 (de) 2001-05-17
SE9301755L (sv) 1995-01-16
US5753518A (en) 1998-05-19
JPH09504859A (ja) 1997-05-13
WO1994028416A1 (en) 1994-12-08

Similar Documents

Publication Publication Date Title
SE504507C2 (sv) Sätt att bestämma bindningsegenskaper hos ligander med låg molekylvikt
van der Merwe et al. Analysis of cell-adhesion molecule interactions using surface plasmon resonance
Gopinath Biosensing applications of surface plasmon resonance-based Biacore technology
US5656504A (en) Method of preventing undesired binding in solid phase assays
US20060211137A1 (en) Biosensor
JP2001510563A (ja) 分析物決定のための方法および系
Bennett et al. Kinetic characterization of the interaction of biotinylated human interleukin 5 with an Fc chimera of its receptor α subunit and development of an ELISA screening assay using real‐time interaction biosensor analysis
Adamczyk et al. Surface plasmon resonance (SPR) as a tool for antibody conjugate analysis
Knoll et al. Supramolecular interfacial architectures for optical biosensing with surface plasmons
US7563624B2 (en) Measurement method using biosensor
Bracke et al. Surface acoustic wave biosensor as a functional quality method in pharmaceutics
US20100291700A1 (en) Analysis of membrane component interactions
Liu et al. Sensitivity-enhancement of wavelength-modulation surface plasmon resonance biosensor for human complement factor 4
JP3996605B2 (ja) 固定化方法、バイオセンサー及び試験方法
JPH05500109A (ja) 検定法
US7425454B2 (en) Biosensor
Zhu et al. Quantitation of basic fibroblast growth factor by immunoassay using BIAcore™ 2000
Kuo et al. Label-free detection of transport kinetics and inhibitor binding of membrane transport proteins with a two-mode plasmonic sensor
Gesty‐Palmer et al. Binding of the soluble, truncated form of an Fc receptor (mouse FcγRII) to membrane‐bound IgG as measured by total internal reflection fluorescence microscopy
Sun et al. Sensitivity enhancement of surface plasmon resonance immunosensing by antibody–antigen coupling
RU2327140C2 (ru) Устройство и способ для качественного и количественного определения химических соединений и биологических объектов
US20060068424A1 (en) Biosensor
EP1783493A1 (en) Biosensor for detecting or measuring a substance that interacts with a physiologically active substance comprising a polysaccharide capable of chemically immobilizing physiologically active subtances
EP1579217B1 (en) Method of determining site-specificity and kit therefor
Julenius Surface plasmon resonance of calcium-binding proteins

Legal Events

Date Code Title Description
NUG Patent has lapsed

Ref document number: 9301755-6

Format of ref document f/p: F