SE460564B - Testsats och foerfarande foer immunanalys med prefabricerade komplex av maerkt antikropp och analytspecifik antikropp - Google Patents
Testsats och foerfarande foer immunanalys med prefabricerade komplex av maerkt antikropp och analytspecifik antikroppInfo
- Publication number
- SE460564B SE460564B SE8501441A SE8501441A SE460564B SE 460564 B SE460564 B SE 460564B SE 8501441 A SE8501441 A SE 8501441A SE 8501441 A SE8501441 A SE 8501441A SE 460564 B SE460564 B SE 460564B
- Authority
- SE
- Sweden
- Prior art keywords
- antibodies
- specific
- enzyme
- analyte
- antigens
- Prior art date
Links
- 239000000427 antigen Substances 0.000 title claims abstract description 33
- 108091007433 antigens Proteins 0.000 title claims abstract description 33
- 102000036639 antigens Human genes 0.000 title claims abstract description 33
- 238000004445 quantitative analysis Methods 0.000 title claims description 11
- 238000004451 qualitative analysis Methods 0.000 title claims description 8
- 108090000790 Enzymes Proteins 0.000 claims abstract description 44
- 102000004190 Enzymes Human genes 0.000 claims abstract description 44
- 239000002245 particle Substances 0.000 claims abstract description 32
- 239000000758 substrate Substances 0.000 claims abstract description 17
- 244000005700 microbiome Species 0.000 claims abstract description 13
- 238000000034 method Methods 0.000 claims description 40
- 239000012491 analyte Substances 0.000 claims description 25
- 241000700605 Viruses Species 0.000 claims description 16
- 108060003951 Immunoglobulin Proteins 0.000 claims description 9
- 102000018358 immunoglobulin Human genes 0.000 claims description 9
- 229940072221 immunoglobulins Drugs 0.000 claims description 8
- 230000009870 specific binding Effects 0.000 claims description 6
- 239000007788 liquid Substances 0.000 claims description 4
- 239000000126 substance Substances 0.000 abstract description 9
- 239000012528 membrane Substances 0.000 abstract description 5
- 238000001514 detection method Methods 0.000 abstract description 4
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 230000000007 visual effect Effects 0.000 abstract 1
- 238000012360 testing method Methods 0.000 description 31
- 239000000523 sample Substances 0.000 description 20
- 210000004027 cell Anatomy 0.000 description 11
- 230000008859 change Effects 0.000 description 10
- 238000006243 chemical reaction Methods 0.000 description 10
- 239000000243 solution Substances 0.000 description 9
- 238000002965 ELISA Methods 0.000 description 8
- 210000002966 serum Anatomy 0.000 description 7
- 241000894006 Bacteria Species 0.000 description 6
- 230000035945 sensitivity Effects 0.000 description 6
- 241000233866 Fungi Species 0.000 description 5
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 5
- 230000004520 agglutination Effects 0.000 description 4
- 230000008901 benefit Effects 0.000 description 4
- 238000003127 radioimmunoassay Methods 0.000 description 4
- 230000000717 retained effect Effects 0.000 description 4
- 238000005406 washing Methods 0.000 description 4
- 241001465754 Metazoa Species 0.000 description 3
- 238000004458 analytical method Methods 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 239000000047 product Substances 0.000 description 3
- 239000011780 sodium chloride Substances 0.000 description 3
- 101100298295 Drosophila melanogaster flfl gene Proteins 0.000 description 2
- 238000001042 affinity chromatography Methods 0.000 description 2
- 238000003149 assay kit Methods 0.000 description 2
- 239000000872 buffer Substances 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000001914 filtration Methods 0.000 description 2
- 238000011534 incubation Methods 0.000 description 2
- 230000007935 neutral effect Effects 0.000 description 2
- 239000008363 phosphate buffer Substances 0.000 description 2
- 239000011148 porous material Substances 0.000 description 2
- 239000002244 precipitate Substances 0.000 description 2
- 238000001556 precipitation Methods 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 238000003825 pressing Methods 0.000 description 2
- 238000007789 sealing Methods 0.000 description 2
- 208000030507 AIDS Diseases 0.000 description 1
- 108010001336 Horseradish Peroxidase Proteins 0.000 description 1
- 206010029719 Nonspecific reaction Diseases 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 230000002776 aggregation Effects 0.000 description 1
- 238000004220 aggregation Methods 0.000 description 1
- 230000000840 anti-viral effect Effects 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 238000003776 cleavage reaction Methods 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 230000008021 deposition Effects 0.000 description 1
- 239000000645 desinfectant Substances 0.000 description 1
- 239000012470 diluted sample Substances 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 208000006454 hepatitis Diseases 0.000 description 1
- 231100000283 hepatitis Toxicity 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 239000000644 isotonic solution Substances 0.000 description 1
- 238000009533 lab test Methods 0.000 description 1
- 238000002372 labelling Methods 0.000 description 1
- 239000004816 latex Substances 0.000 description 1
- 229920000126 latex Polymers 0.000 description 1
- 210000004698 lymphocyte Anatomy 0.000 description 1
- 229920002521 macromolecule Polymers 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- ZNNZYHKDIALBAK-UHFFFAOYSA-M potassium thiocyanate Chemical compound [K+].[S-]C#N ZNNZYHKDIALBAK-UHFFFAOYSA-M 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000009257 reactivity Effects 0.000 description 1
- 230000007017 scission Effects 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/535—Production of labelled immunochemicals with enzyme label or co-enzymes, co-factors, enzyme inhibitors or enzyme substrates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8501441A SE460564B (sv) | 1985-03-25 | 1985-03-25 | Testsats och foerfarande foer immunanalys med prefabricerade komplex av maerkt antikropp och analytspecifik antikropp |
| PCT/SE1986/000309 WO1988000345A1 (en) | 1985-03-25 | 1986-06-26 | Method and apparatus for qualitative and/or quantitative analysis of antigens, antibodies, mircroorganisms or other cells |
| DE86904435T DE3684607D1 (no) | 1985-03-25 | 1986-06-26 | |
| EP86904435A EP0311604B1 (en) | 1985-03-25 | 1986-06-26 | Method and apparatus for qualitative and/or quantitative analysis of antigens, antibodies, mircroorganisms or other cells |
| NO88880835A NO880835L (no) | 1985-03-25 | 1988-02-25 | Fremgangsmaate og anordning for kvalitativ og/eller kvantitativ analyse av antigener, antistoffer, mikroorganismer eller andre celler. |
| DK104988A DK104988A (da) | 1985-03-25 | 1988-02-26 | Fremgangsmaade og apparat til kvalitativ og/eller kvantitativ analyse af antigener, antistoffer, mikroorganismer eller andre celler |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8501441A SE460564B (sv) | 1985-03-25 | 1985-03-25 | Testsats och foerfarande foer immunanalys med prefabricerade komplex av maerkt antikropp och analytspecifik antikropp |
| PCT/SE1986/000309 WO1988000345A1 (en) | 1985-03-25 | 1986-06-26 | Method and apparatus for qualitative and/or quantitative analysis of antigens, antibodies, mircroorganisms or other cells |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| SE8501441D0 SE8501441D0 (sv) | 1985-03-25 |
| SE8501441L SE8501441L (sv) | 1986-09-26 |
| SE460564B true SE460564B (sv) | 1989-10-23 |
Family
ID=26658917
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE8501441A SE460564B (sv) | 1985-03-25 | 1985-03-25 | Testsats och foerfarande foer immunanalys med prefabricerade komplex av maerkt antikropp och analytspecifik antikropp |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0311604B1 (no) |
| DE (1) | DE3684607D1 (no) |
| DK (1) | DK104988A (no) |
| NO (1) | NO880835L (no) |
| SE (1) | SE460564B (no) |
| WO (1) | WO1988000345A1 (no) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5003988A (en) * | 1989-06-21 | 1991-04-02 | La Mina Ltd. | Modular multiple fluid sample preparation assembly |
| US4961432A (en) * | 1989-01-10 | 1990-10-09 | Cancer Diagnostics, Inc. | Modular fluid sample preparation assembly |
| US5358690A (en) * | 1989-01-10 | 1994-10-25 | Lamina, Ltd. | Environmental sample collection and membrane testing device |
| JP3093833B2 (ja) * | 1991-01-22 | 2000-10-03 | 長瀬産業株式会社 | う蝕原性菌の検出定量方法 |
| EP3249404B1 (en) * | 2015-01-22 | 2019-10-02 | NEC Solution Innovators, Ltd. | Target analysis apparatus and target analysis method |
| JP6660630B2 (ja) * | 2016-07-20 | 2020-03-11 | Ｎｅｃソリューションイノベータ株式会社 | ターゲット分析キットおよびターゲット分析方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4407943A (en) * | 1976-12-16 | 1983-10-04 | Millipore Corporation | Immobilized antibody or antigen for immunoassay |
| GB2084317B (en) * | 1980-09-30 | 1984-01-18 | Erba Farmitalia | Antigen-linked competitive enzymeimmunoassay |
| FR2514367A1 (fr) * | 1981-10-08 | 1983-04-15 | Pasteur Institut | Procede pour la detection de germes pathogenes dans des fluides par filtration sur des immunoadsorbants, et application a la determination de la potabilite d'une eau |
| US4459361A (en) * | 1982-06-04 | 1984-07-10 | Angenics, Inc. | Ligand assay with one or two particulate reagents and filter |
| US4786471A (en) * | 1983-10-21 | 1988-11-22 | Baxter Travenol Laboratories, Inc. | Heterogeneous immunoassay method and assembly |
| US4632901A (en) * | 1984-05-11 | 1986-12-30 | Hybritech Incorporated | Method and apparatus for immunoassays |
| EP0227679A1 (en) * | 1984-09-26 | 1987-07-08 | ANDERSSON, Jan Peter | Device and method for trapping and analyzing particles |
-
1985
- 1985-03-25 SE SE8501441A patent/SE460564B/sv not_active IP Right Cessation
-
1986
- 1986-06-26 WO PCT/SE1986/000309 patent/WO1988000345A1/en active IP Right Grant
- 1986-06-26 EP EP86904435A patent/EP0311604B1/en not_active Expired - Lifetime
- 1986-06-26 DE DE86904435T patent/DE3684607D1/de not_active Expired - Fee Related
-
1988
- 1988-02-25 NO NO88880835A patent/NO880835L/no unknown
- 1988-02-26 DK DK104988A patent/DK104988A/da not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| SE8501441L (sv) | 1986-09-26 |
| DK104988D0 (da) | 1988-02-26 |
| NO880835D0 (no) | 1988-02-25 |
| WO1988000345A1 (en) | 1988-01-14 |
| SE8501441D0 (sv) | 1985-03-25 |
| DK104988A (da) | 1988-02-26 |
| EP0311604A1 (en) | 1989-04-19 |
| EP0311604B1 (en) | 1992-03-25 |
| NO880835L (no) | 1988-04-25 |
| DE3684607D1 (no) | 1992-04-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NUG | Patent has lapsed |
Ref document number: 8501441-3 Effective date: 19931008 Format of ref document f/p: F |