SE454781B - Hybridiseringsforfarande for detektion av polynukleotidsekvens - Google Patents

Hybridiseringsforfarande for detektion av polynukleotidsekvens

Info

Publication number
SE454781B
SE454781B SE8604436A SE8604436A SE454781B SE 454781 B SE454781 B SE 454781B SE 8604436 A SE8604436 A SE 8604436A SE 8604436 A SE8604436 A SE 8604436A SE 454781 B SE454781 B SE 454781B
Authority
SE
Sweden
Prior art keywords
dna
nucleic acid
sequence
water
probe
Prior art date
Application number
SE8604436A
Other languages
English (en)
Swedish (sv)
Other versions
SE8604436D0 (sv
SE8604436L (sv
Inventor
J Ylikoski
P Hurskainen
P Dahlen
C Sund
T Lovgren
M Kwiatkowski
Original Assignee
Wallac Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wallac Oy filed Critical Wallac Oy
Priority to SE8604436A priority Critical patent/SE454781B/sv
Publication of SE8604436D0 publication Critical patent/SE8604436D0/xx
Priority to DE8787907035T priority patent/DE3784058T2/de
Priority to AT87907035T priority patent/ATE85367T1/de
Priority to US07/207,159 priority patent/US5256535A/en
Priority to EP87907035A priority patent/EP0288513B1/fr
Priority to JP62506689A priority patent/JPH01501681A/ja
Priority to PCT/SE1987/000474 priority patent/WO1988002784A1/fr
Publication of SE8604436L publication Critical patent/SE8604436L/xx
Publication of SE454781B publication Critical patent/SE454781B/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
SE8604436A 1986-10-17 1986-10-17 Hybridiseringsforfarande for detektion av polynukleotidsekvens SE454781B (sv)

Priority Applications (7)

Application Number Priority Date Filing Date Title
SE8604436A SE454781B (sv) 1986-10-17 1986-10-17 Hybridiseringsforfarande for detektion av polynukleotidsekvens
DE8787907035T DE3784058T2 (de) 1986-10-17 1987-10-16 Hybridisierungs-test und vorrichtungen zur durchfuehrung dieses tests.
AT87907035T ATE85367T1 (de) 1986-10-17 1987-10-16 Hybridisierungs-test und vorrichtungen zur durchfuehrung dieses tests.
US07/207,159 US5256535A (en) 1986-10-17 1987-10-16 Hybridization assay and means to be used in the assay
EP87907035A EP0288513B1 (fr) 1986-10-17 1987-10-16 Test d'hybridation et moyens utilises pour le test
JP62506689A JPH01501681A (ja) 1986-10-17 1987-10-16 ハイブリダイゼーションアッセイ及び該アッセイに使用されるベき手段
PCT/SE1987/000474 WO1988002784A1 (fr) 1986-10-17 1987-10-16 Test d'hybridation et moyens utilises pour le test

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8604436A SE454781B (sv) 1986-10-17 1986-10-17 Hybridiseringsforfarande for detektion av polynukleotidsekvens

Publications (3)

Publication Number Publication Date
SE8604436D0 SE8604436D0 (sv) 1986-10-17
SE8604436L SE8604436L (sv) 1988-04-18
SE454781B true SE454781B (sv) 1988-05-30

Family

ID=20365979

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8604436A SE454781B (sv) 1986-10-17 1986-10-17 Hybridiseringsforfarande for detektion av polynukleotidsekvens

Country Status (7)

Country Link
US (1) US5256535A (fr)
EP (1) EP0288513B1 (fr)
JP (1) JPH01501681A (fr)
AT (1) ATE85367T1 (fr)
DE (1) DE3784058T2 (fr)
SE (1) SE454781B (fr)
WO (1) WO1988002784A1 (fr)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6127529A (en) * 1988-06-29 2000-10-03 Wallac Oy Metal-chelating 2,6-disubstituted pyridine compounds and their use
SE8802574D0 (sv) * 1988-07-08 1988-07-08 Wallac Oy Oligonucleotide hybridization probes and means for the synthesis of the most preferred probes
FR2638462B1 (fr) * 1988-10-28 1992-05-22 Oris Ind Complexes tridimensionnels a base de streptavidine (ou avidine) et de composes luminescents polybiotinyles
GB8927503D0 (en) * 1989-12-04 1990-02-07 Kronem Systems Inc Enzyme-amplified lanthanide chelate luminescence
WO1991010908A1 (fr) * 1990-01-17 1991-07-25 Wallac Oy Derives d'oligosaccharide relies a des chelates de lanthanides et a un groupe reactif
AU653012B2 (en) * 1991-02-14 1994-09-15 Microscan, Inc. Novel lanthanide chelate-conjugated oligonucleotides
FI96143C (fi) * 1993-03-16 1996-05-10 Wallac Oy Biospesifinen määritysmenetelmä
FI93781C (fi) * 1993-03-18 1995-05-26 Wallac Oy Biospesifinen multiparametrinen määritysmenetelmä
FR2710075B1 (fr) * 1993-09-15 1995-10-27 Bio Merieux Réactif et procédé pour la détection d'une séquence nucléotidique avec amplification de signal.
FR2746413B1 (fr) * 1996-03-19 1998-04-24 Bio Merieux Detection d'une sequence nucleotidique avec amplification de signal
EP0917533A2 (fr) * 1996-07-03 1999-05-26 President And Fellows Of Harvard College Segment de liaison pour oligonucleotide et techniques comprenant des oligonucleotides immobilises et lies
US7745142B2 (en) 1997-09-15 2010-06-29 Molecular Devices Corporation Molecular modification assays
US6297018B1 (en) 1998-04-17 2001-10-02 Ljl Biosystems, Inc. Methods and apparatus for detecting nucleic acid polymorphisms
US6289229B1 (en) 1998-01-20 2001-09-11 Scimed Life Systems, Inc. Readable probe array for in vivo use
US6030840A (en) * 1998-06-15 2000-02-29 Nen Life Sciences, Inc. Neutral enhancement of lanthanides for time resolved fluorescence
US20010055763A1 (en) * 1998-12-24 2001-12-27 Sharat Singh Individually addressable solid surfaces for multiplexed operations
US6309836B1 (en) 1999-10-05 2001-10-30 Marek Kwiatkowski Compounds for protecting hydroxyls and methods for their use
US6406851B1 (en) 2000-01-28 2002-06-18 Agilent Technologies, Inc. Method for coating a substrate quickly and uniformly with a small volume of fluid
US6458526B1 (en) 2000-01-28 2002-10-01 Agilent Technologies, Inc. Method and apparatus to inhibit bubble formation in a fluid
FI20000333A0 (fi) * 2000-02-16 2000-02-16 Jussi Nurmi Homogeeninen menetelmä polynukleotidin havaitsemiseksi
US20040115692A1 (en) * 2000-04-03 2004-06-17 Cytyc Corporation Methods, compositions and apparatuses for detecting a target in a preservative solution
BR0112871A (pt) * 2000-08-04 2003-04-22 Sensors For Med & Science Inc Detecção de analitos para ambientes aquosos
US6806051B2 (en) * 2000-09-25 2004-10-19 Picoliter Inc. Arrays of partially nonhybridizing oligonucleotides and preparation thereof using focused acoustic energy
US6927029B2 (en) 2001-12-03 2005-08-09 Agilent Technologies, Inc. Surface with tethered polymeric species for binding biomolecules
US8394944B2 (en) * 2002-09-20 2013-03-12 Siemens Healthcare Diagnostics Inc. Dual-purpose primers and probes for providing enhanced hybridization assays by disruption of secondary structure formation
EP1725572B1 (fr) * 2003-11-05 2017-05-31 AGCT GmbH Composes nucleotidiques macromoleculaires et leurs procedes d'utilisation
CA2581639C (fr) * 2004-09-30 2016-07-26 Molecular Devices Corporation Complexes de lanthanides luminescents
WO2006097320A2 (fr) 2005-03-17 2006-09-21 Genovoxx Gmbh Liaisons nucleotidiques macromoleculaires et procedes d'utilisation associes
CN107573445B (zh) * 2006-05-27 2021-05-25 富鲁达加拿大公司 聚合物骨架元素标签
WO2008043426A2 (fr) * 2006-09-20 2008-04-17 Genovoxx Gmbh Constituants et procédés de synthèse enzymatique d'acides nucléiques
CN104411406B (zh) 2012-03-16 2017-05-31 统计诊断与创新有限公司 具有集成传送模块的测试盒
CN111562244B (zh) * 2020-05-25 2023-02-07 赣南师范大学 一种检测柔红霉素的稀土时间分辨荧光探针和试剂盒
CN114062328A (zh) * 2020-08-10 2022-02-18 深圳先进技术研究院 一种基于核酸杂交增强稀土配合物荧光的检测方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1111762A (fr) * 1977-12-28 1981-11-03 David S. Frank Chelate de terre rare fluorescent dans des particules de latex polymerique
US4283382A (en) * 1977-12-28 1981-08-11 Eastman Kodak Company Fluorescent labels comprising rare earth chelates
US4259313A (en) * 1978-10-18 1981-03-31 Eastman Kodak Company Fluorescent labels
AT357247B (de) * 1978-12-27 1980-06-25 Vianova Kunstharz Ag Verfahren zur herstellung von selbstver- netzenden bindemitteln fuer kathodisch abscheid- bare elektrotauchlacke
US4434150A (en) * 1981-10-19 1984-02-28 Ortho Diagnostic Systems, Inc. Immunological reagents employing polymeric backbone possessing reactive functional groups
CA1223831A (fr) * 1982-06-23 1987-07-07 Dean Engelhardt Nucleotides modifies, methodes de preparation et d'utilisation et composes les contenant
SE8301395L (sv) * 1983-03-15 1984-09-16 Wallac Oy Kelatiserande foreningar med funktionella grupper vilka tillater kovalent koppling till bio-organiska molekyler
US4707440A (en) * 1984-01-30 1987-11-17 Enzo Biochem, Inc. Nucleic acid hybridization assay and detectable molecules useful in such assay
FR2570703B1 (fr) * 1984-09-26 1988-07-08 Commissariat Energie Atomique Complexes macropolycycliques de terres rares et application a titre de marqueurs fluorescents
US4670379A (en) * 1984-12-19 1987-06-02 E. I. Du Pont De Nemours And Company Polynucleotide hydridization assays employing catalyzed luminescence
ATE40572T1 (de) * 1985-01-10 1989-02-15 Molecular Diagnostics Inc Photochemisches verfahren zum markieren von nucleinsaeuren zum nachweis in hybridisationsproben.
US4795700A (en) * 1985-01-25 1989-01-03 California Institute Of Technology Nucleic acid probes and methods of using same
US4719182A (en) * 1985-03-18 1988-01-12 Eastman Kodak Company Fluorescent labels and labeled species and their use in analytical elements and determinations
JP2509574B2 (ja) * 1985-08-15 1996-06-19 アモコ・コーポレーション 標識付けした核酸
WO1987002708A1 (fr) * 1985-10-24 1987-05-07 Siska Diagnostics, Inc. Sondes d'acide nucleique marquees par des composes chelates de lanthanides
GB8621337D0 (en) * 1986-09-04 1986-10-15 Agricultural Genetics Co Non-radioactive nucleic acid hybridization probes
EP0297373A3 (fr) * 1987-06-25 1990-11-07 Colgate-Palmolive Company Monoperoxyphtalate de magnésium granulaire enduit d'acides gras pour éviter la détérioration de la teinture des tissus sensibles au blanchiment

Also Published As

Publication number Publication date
WO1988002784A1 (fr) 1988-04-21
DE3784058D1 (de) 1993-03-18
DE3784058T2 (de) 1993-05-19
EP0288513B1 (fr) 1993-02-03
EP0288513A1 (fr) 1988-11-02
SE8604436D0 (sv) 1986-10-17
ATE85367T1 (de) 1993-02-15
US5256535A (en) 1993-10-26
SE8604436L (sv) 1988-04-18
JPH01501681A (ja) 1989-06-15

Similar Documents

Publication Publication Date Title
SE454781B (sv) Hybridiseringsforfarande for detektion av polynukleotidsekvens
EP0360940B1 (fr) Détermination de polynucléotides aux sites de scission sélectables
US6221581B1 (en) Processes for detecting polynucleotides, determining genetic mutations or defects in genetic material, separating or isolating nucleic acid of interest from samples, and useful compositions of matter and multihybrid complex compositions
US9134302B2 (en) Analyte detection utilizing polynucleotide sequences, composition, process and kit
JP2797047B2 (ja) 受身固定により核酸フラグメントを固体支持体上に不動化する方法、そのようにして得られた固体支持体およびその使用
US7279311B2 (en) Use of nucleic acids bound to carrier macromolecules
US5288609A (en) Capture sandwich hybridization method and composition
US5705346A (en) Method for detecting a target nucleic acid by using an interaction of two kinds of reagents
JP2742905B2 (ja) 核酸配列の検出方法
EP0526912B1 (fr) Procédés pour la détection d'un matériau génétique cible monocanténair
US4898951A (en) Compounds used as intermediates in the preparations of non-radioactive biological probes
EP1247815A2 (fr) Oligonucléotides modifiés et leurs utilisations
EP0703296A1 (fr) Détermination de polynucléotides par substitution de brin avec une sonde de capture
EP1831400A2 (fr) Complexes, reseaux d'etiquettes d'identite et procedes d'utilisation afferents
EP0155854B1 (fr) Matériel de test biologique non-radioactif
EP0610215A1 (fr) Dosage de polynucleotides a l'aide de sites de clivage pouvant etre selectionnes
WO1996027679A1 (fr) Modulation des proprietes de liaison de partenaires de liaison de l'acide nucleique
JP2003194824A (ja) 蛍光性物質および蛍光標識方法

Legal Events

Date Code Title Description
NAL Patent in force

Ref document number: 8604436-9

Format of ref document f/p: F

NUG Patent has lapsed