ATE85367T1 - Hybridisierungs-test und vorrichtungen zur durchfuehrung dieses tests. - Google Patents

Hybridisierungs-test und vorrichtungen zur durchfuehrung dieses tests.

Info

Publication number
ATE85367T1
ATE85367T1 AT87907035T AT87907035T ATE85367T1 AT E85367 T1 ATE85367 T1 AT E85367T1 AT 87907035 T AT87907035 T AT 87907035T AT 87907035 T AT87907035 T AT 87907035T AT E85367 T1 ATE85367 T1 AT E85367T1
Authority
AT
Austria
Prior art keywords
pct
nucleic acid
nucleotide sequence
rare earth
earth metal
Prior art date
Application number
AT87907035T
Other languages
English (en)
Inventor
Jyrki Ylikoski
Pertti Hurskainen
Patrik Dahlen
Christian Sund
Timo Loevgren
Marek Kwiatkowski
Original Assignee
Wallac Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wallac Oy filed Critical Wallac Oy
Application granted granted Critical
Publication of ATE85367T1 publication Critical patent/ATE85367T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT87907035T 1986-10-17 1987-10-16 Hybridisierungs-test und vorrichtungen zur durchfuehrung dieses tests. ATE85367T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE8604436A SE454781B (sv) 1986-10-17 1986-10-17 Hybridiseringsforfarande for detektion av polynukleotidsekvens
EP87907035A EP0288513B1 (de) 1986-10-17 1987-10-16 Hybridisierungs-test und vorrichtungen zur durchführung dieses tests
PCT/SE1987/000474 WO1988002784A1 (en) 1986-10-17 1987-10-16 Hybridization assay and means to be used in the assay

Publications (1)

Publication Number Publication Date
ATE85367T1 true ATE85367T1 (de) 1993-02-15

Family

ID=20365979

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87907035T ATE85367T1 (de) 1986-10-17 1987-10-16 Hybridisierungs-test und vorrichtungen zur durchfuehrung dieses tests.

Country Status (7)

Country Link
US (1) US5256535A (de)
EP (1) EP0288513B1 (de)
JP (1) JPH01501681A (de)
AT (1) ATE85367T1 (de)
DE (1) DE3784058T2 (de)
SE (1) SE454781B (de)
WO (1) WO1988002784A1 (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6127529A (en) * 1988-06-29 2000-10-03 Wallac Oy Metal-chelating 2,6-disubstituted pyridine compounds and their use
SE8802574D0 (sv) * 1988-07-08 1988-07-08 Wallac Oy Oligonucleotide hybridization probes and means for the synthesis of the most preferred probes
FR2638462B1 (fr) * 1988-10-28 1992-05-22 Oris Ind Complexes tridimensionnels a base de streptavidine (ou avidine) et de composes luminescents polybiotinyles
GB8927503D0 (en) * 1989-12-04 1990-02-07 Kronem Systems Inc Enzyme-amplified lanthanide chelate luminescence
WO1991010908A1 (en) * 1990-01-17 1991-07-25 Wallac Oy Oligosaccharide derivates linked to lanthanide chelates and to a reactive group
DE69221404T2 (de) * 1991-02-14 1998-02-05 Dade Microscan Inc., Sacramento, Calif. Neue oligonukleotide konjugiert zu lanthanide-chelaten
FI96143C (fi) * 1993-03-16 1996-05-10 Wallac Oy Biospesifinen määritysmenetelmä
FI93781C (fi) * 1993-03-18 1995-05-26 Wallac Oy Biospesifinen multiparametrinen määritysmenetelmä
FR2710075B1 (fr) * 1993-09-15 1995-10-27 Bio Merieux Réactif et procédé pour la détection d'une séquence nucléotidique avec amplification de signal.
FR2746413B1 (fr) * 1996-03-19 1998-04-24 Bio Merieux Detection d'une sequence nucleotidique avec amplification de signal
AU739391B2 (en) * 1996-07-03 2001-10-11 President And Fellows Of Harvard College Oligonucleotide linker and techniques involving immobilized and linked oligonucleotides
US7745142B2 (en) 1997-09-15 2010-06-29 Molecular Devices Corporation Molecular modification assays
US6297018B1 (en) 1998-04-17 2001-10-02 Ljl Biosystems, Inc. Methods and apparatus for detecting nucleic acid polymorphisms
US6289229B1 (en) 1998-01-20 2001-09-11 Scimed Life Systems, Inc. Readable probe array for in vivo use
US6030840A (en) * 1998-06-15 2000-02-29 Nen Life Sciences, Inc. Neutral enhancement of lanthanides for time resolved fluorescence
US20010055763A1 (en) * 1998-12-24 2001-12-27 Sharat Singh Individually addressable solid surfaces for multiplexed operations
US6309836B1 (en) 1999-10-05 2001-10-30 Marek Kwiatkowski Compounds for protecting hydroxyls and methods for their use
US6406851B1 (en) * 2000-01-28 2002-06-18 Agilent Technologies, Inc. Method for coating a substrate quickly and uniformly with a small volume of fluid
US6458526B1 (en) 2000-01-28 2002-10-01 Agilent Technologies, Inc. Method and apparatus to inhibit bubble formation in a fluid
FI20000333A0 (fi) * 2000-02-16 2000-02-16 Jussi Nurmi Homogeeninen menetelmä polynukleotidin havaitsemiseksi
US20040115692A1 (en) * 2000-04-03 2004-06-17 Cytyc Corporation Methods, compositions and apparatuses for detecting a target in a preservative solution
EP1557422B1 (de) * 2000-08-04 2013-12-25 Senseonics, Incorporated Nachweis von Analyten in wässrigen Medien
US6806051B2 (en) * 2000-09-25 2004-10-19 Picoliter Inc. Arrays of partially nonhybridizing oligonucleotides and preparation thereof using focused acoustic energy
US6927029B2 (en) 2001-12-03 2005-08-09 Agilent Technologies, Inc. Surface with tethered polymeric species for binding biomolecules
US8394944B2 (en) * 2002-09-20 2013-03-12 Siemens Healthcare Diagnostics Inc. Dual-purpose primers and probes for providing enhanced hybridization assays by disruption of secondary structure formation
US8637650B2 (en) 2003-11-05 2014-01-28 Genovoxx Gmbh Macromolecular nucleotide compounds and methods for using the same
CA2581639C (en) * 2004-09-30 2016-07-26 Molecular Devices Corporation Luminescent lanthanide complexes
WO2006097320A2 (de) 2005-03-17 2006-09-21 Genovoxx Gmbh Makromolekulare nukleotidverbindungen und methoden zu deren anwendung
WO2007137418A1 (en) 2006-05-27 2007-12-06 Winnik Mitchell A Polymer backbone element tags
WO2008043426A2 (de) * 2006-09-20 2008-04-17 Genovoxx Gmbh Komponenten und verfahren zur enzymatischen synthese von nukleinsäuren
RU2652441C2 (ru) 2012-03-16 2018-04-26 Стат-Диагностика Энд Инновэйшн, С.Л. Кассета для тестирования со встроенным передаточным модулем
CN111562244B (zh) * 2020-05-25 2023-02-07 赣南师范大学 一种检测柔红霉素的稀土时间分辨荧光探针和试剂盒
CN114062328B (zh) * 2020-08-10 2024-08-27 深圳先进技术研究院 一种基于核酸杂交增强稀土配合物荧光的检测方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1111762A (en) * 1977-12-28 1981-11-03 David S. Frank Fluorescent rare earth chelate in polymeric latex particles
US4283382A (en) * 1977-12-28 1981-08-11 Eastman Kodak Company Fluorescent labels comprising rare earth chelates
US4259313A (en) * 1978-10-18 1981-03-31 Eastman Kodak Company Fluorescent labels
AT357247B (de) * 1978-12-27 1980-06-25 Vianova Kunstharz Ag Verfahren zur herstellung von selbstver- netzenden bindemitteln fuer kathodisch abscheid- bare elektrotauchlacke
US4434150A (en) * 1981-10-19 1984-02-28 Ortho Diagnostic Systems, Inc. Immunological reagents employing polymeric backbone possessing reactive functional groups
CA1223831A (en) * 1982-06-23 1987-07-07 Dean Engelhardt Modified nucleotides, methods of preparing and utilizing and compositions containing the same
SE8301395L (sv) * 1983-03-15 1984-09-16 Wallac Oy Kelatiserande foreningar med funktionella grupper vilka tillater kovalent koppling till bio-organiska molekyler
US4707440A (en) * 1984-01-30 1987-11-17 Enzo Biochem, Inc. Nucleic acid hybridization assay and detectable molecules useful in such assay
FR2570703B1 (fr) * 1984-09-26 1988-07-08 Commissariat Energie Atomique Complexes macropolycycliques de terres rares et application a titre de marqueurs fluorescents
US4670379A (en) * 1984-12-19 1987-06-02 E. I. Du Pont De Nemours And Company Polynucleotide hydridization assays employing catalyzed luminescence
ATE40572T1 (de) * 1985-01-10 1989-02-15 Molecular Diagnostics Inc Photochemisches verfahren zum markieren von nucleinsaeuren zum nachweis in hybridisationsproben.
US4795700A (en) * 1985-01-25 1989-01-03 California Institute Of Technology Nucleic acid probes and methods of using same
US4719182A (en) * 1985-03-18 1988-01-12 Eastman Kodak Company Fluorescent labels and labeled species and their use in analytical elements and determinations
JP2509574B2 (ja) * 1985-08-15 1996-06-19 アモコ・コーポレーション 標識付けした核酸
WO1987002708A1 (en) * 1985-10-24 1987-05-07 Siska Diagnostics, Inc. Lanthanide chelate-tagged nucleic acid probes
GB8621337D0 (en) * 1986-09-04 1986-10-15 Agricultural Genetics Co Non-radioactive nucleic acid hybridization probes
EP0297373A3 (de) * 1987-06-25 1990-11-07 Colgate-Palmolive Company Mit Fettsäuren überzogenes granuliertes Magnesiummonoperoxyphthalat zur Verhinderung von Farbschäden an gegen Bleichmittel empfindlichen Geweben

Also Published As

Publication number Publication date
DE3784058D1 (de) 1993-03-18
SE8604436D0 (sv) 1986-10-17
US5256535A (en) 1993-10-26
WO1988002784A1 (en) 1988-04-21
EP0288513A1 (de) 1988-11-02
SE8604436L (sv) 1988-04-18
DE3784058T2 (de) 1993-05-19
JPH01501681A (ja) 1989-06-15
SE454781B (sv) 1988-05-30
EP0288513B1 (de) 1993-02-03

Similar Documents

Publication Publication Date Title
ATE85367T1 (de) Hybridisierungs-test und vorrichtungen zur durchfuehrung dieses tests.
ATE127530T1 (de) Universelle nukleinsäuresonden für eubakterien sowie methoden.
WO2000055368A3 (en) Probe/mobility modifier complexes for multiplex nucleic acid detection
BR9507960A (pt) Sondas processos e kits para detenção de acidos nucleicos mycobacteriais em amostras biologicas
DE502589T1 (de) Kit zur verwendung bei der amplifizierung und beim nachweis von nukleinsaeuresequenzen.
ES8707343A1 (es) Un metodo para aislar una secuencia de acido nucleico objetivo seleccionada
ES8800349A1 (es) Un metodo de caracterizacion de una muestra a ensayar de dnagenomico.
ES2039294T3 (es) Metodo para detectar secuencias de nucleotidos.
WO2001061033A3 (en) Multiplex ligatable probe amplification
FI900602A0 (fi) Bestaemning.
ATE351923T1 (de) Diagnostische methode zur identifizierung von fötaler dna in einer maternalen probe
KR880700811A (ko) 잡종형성에 의하여 세균 및 기타 살아있는 유기체를 검출하기 위한 올리고 핵삼염 소식자 및 검출 방법
DE3856224D1 (de) Nachweis eines Polynukleotids durch Ersätzung einer Kette an einer Fangsonde
EP0305145A3 (de) Verfahren und Sonden zur Bestimmung von Nukleinsäuren
DE69018961D1 (de) Detektion von pneumocystis carinii durch die verwendung von nukleinsäuresonden.
WO1993020230A1 (en) Electrochemical detection of dna hybridisation
DE3485811D1 (de) Molekulare genetische sonde und verfahren zu ihrer herstellung, testmethode und satz in denen diese molekulare genetische sonde gebraucht wird.
ATE67790T1 (de) Hybridisierungsverfahren und proben dafuer.
KR970704891A (ko) Hla-dr 타입 결정용 프로브 시스템 및 이를 이용한 타입 결정 방법
ATE127856T1 (de) Nukleinsäuresonden für die detektion von neisseria gonorrhoeae.
WO1998024928A3 (en) Detection of chromosomal abnormalities
WO1997046709A3 (en) NUCLEIC ACID PRIMERS AND PROBES FOR DETECTING $i(CHLAMYDIA PNEUMONIAE)
ATE191512T1 (de) Nukleinsäure sonden welche bei nachweis von shigellabakterien verwendbar sind
WO1998000565A3 (en) NUCLEIC ACID PRIMERS AND PROBES FOR DETECTING $i(MYCOPLASMA PNEUMONIAE)
RU98100753A (ru) Способ выявления анализируемой последовательности нуклеиновых кислот

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties