SE454442B - Forfarande for framstellning av 4-metoxi-2'-(2-(1-metyl-2-piperidyl)etyl)-bensamid(enkainid) och 2-(2-pyridylacetyl)-p-anisanilid som mellanprodukt - Google Patents
Forfarande for framstellning av 4-metoxi-2'-(2-(1-metyl-2-piperidyl)etyl)-bensamid(enkainid) och 2-(2-pyridylacetyl)-p-anisanilid som mellanproduktInfo
- Publication number
- SE454442B SE454442B SE8207112A SE8207112A SE454442B SE 454442 B SE454442 B SE 454442B SE 8207112 A SE8207112 A SE 8207112A SE 8207112 A SE8207112 A SE 8207112A SE 454442 B SE454442 B SE 454442B
- Authority
- SE
- Sweden
- Prior art keywords
- hydrogen
- equivalents
- anisanilide
- pyridylacetyl
- methyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/46—Oxygen atoms
- C07D213/50—Ketonic radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/330,298 US4394507A (en) | 1981-12-14 | 1981-12-14 | Process for production of encainide |
Publications (3)
Publication Number | Publication Date |
---|---|
SE8207112D0 SE8207112D0 (sv) | 1982-12-13 |
SE8207112L SE8207112L (sv) | 1983-06-15 |
SE454442B true SE454442B (sv) | 1988-05-02 |
Family
ID=23289147
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE8207112A SE454442B (sv) | 1981-12-14 | 1982-12-13 | Forfarande for framstellning av 4-metoxi-2'-(2-(1-metyl-2-piperidyl)etyl)-bensamid(enkainid) och 2-(2-pyridylacetyl)-p-anisanilid som mellanprodukt |
Country Status (16)
Country | Link |
---|---|
US (1) | US4394507A (ko) |
JP (1) | JPS6058231B2 (ko) |
KR (1) | KR890000419B1 (ko) |
AT (1) | AT378182B (ko) |
CA (1) | CA1213282A (ko) |
CH (1) | CH655101A5 (ko) |
DK (1) | DK156648C (ko) |
ES (2) | ES517996A0 (ko) |
FI (1) | FI76561C (ko) |
GR (1) | GR77107B (ko) |
HU (1) | HU186190B (ko) |
IT (1) | IT1149399B (ko) |
NL (1) | NL8204775A (ko) |
PT (1) | PT75980B (ko) |
SE (1) | SE454442B (ko) |
YU (1) | YU44035B (ko) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4675409A (en) * | 1986-02-25 | 1987-06-23 | Bristol-Myers Company | Process for the preparation of encainide |
US4800226A (en) * | 1986-02-25 | 1989-01-24 | Bristol-Myers Company | Process intermediate for the preparation of encainide |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2317303A (en) * | 1940-12-07 | 1943-04-20 | Merck & Co Inc | Heterocyclic nitrogen containing compounds, and processes for making the same |
US3931195A (en) * | 1971-03-03 | 1976-01-06 | Mead Johnson & Company | Substituted piperidines |
CA961038A (en) * | 1971-03-03 | 1975-01-14 | Joseph L. Minielli | Substituted piperidines |
US4064254A (en) * | 1971-03-03 | 1977-12-20 | Mead Johnson & Company | Substituted piperidines therapeutic process and compositions |
US4000143A (en) * | 1971-03-03 | 1976-12-28 | Mead Johnson & Company | Substituted piperidines |
SE7607114L (sv) * | 1976-06-22 | 1977-12-23 | Bofors Ab | Sett att framstella hydrokloriden av n-metylpiperidin-2-karbonsyra-2,6-xyllidid |
-
1981
- 1981-12-14 US US06/330,298 patent/US4394507A/en not_active Expired - Fee Related
-
1982
- 1982-11-18 GR GR69848A patent/GR77107B/el unknown
- 1982-11-22 CA CA000416079A patent/CA1213282A/en not_active Expired
- 1982-11-25 KR KR8205318A patent/KR890000419B1/ko active
- 1982-12-02 IT IT49608/82A patent/IT1149399B/it active
- 1982-12-07 YU YU2710/82A patent/YU44035B/xx unknown
- 1982-12-07 ES ES517996A patent/ES517996A0/es active Granted
- 1982-12-09 JP JP57214747A patent/JPS6058231B2/ja not_active Expired
- 1982-12-09 NL NL8204775A patent/NL8204775A/nl unknown
- 1982-12-09 FI FI824234A patent/FI76561C/fi not_active IP Right Cessation
- 1982-12-10 DK DK551582A patent/DK156648C/da not_active IP Right Cessation
- 1982-12-13 PT PT75980A patent/PT75980B/pt not_active IP Right Cessation
- 1982-12-13 SE SE8207112A patent/SE454442B/sv not_active IP Right Cessation
- 1982-12-13 HU HU824018A patent/HU186190B/hu not_active IP Right Cessation
- 1982-12-13 CH CH7245/82A patent/CH655101A5/de not_active IP Right Cessation
- 1982-12-14 AT AT0454082A patent/AT378182B/de not_active IP Right Cessation
-
1984
- 1984-03-01 ES ES530218A patent/ES530218A0/es active Granted
Also Published As
Publication number | Publication date |
---|---|
YU271082A (en) | 1985-03-20 |
SE8207112D0 (sv) | 1982-12-13 |
DK156648B (da) | 1989-09-18 |
KR840002355A (ko) | 1984-06-25 |
CA1213282A (en) | 1986-10-28 |
ES8506274A1 (es) | 1985-07-01 |
ATA454082A (de) | 1984-11-15 |
CH655101A5 (de) | 1986-03-27 |
FI824234L (fi) | 1983-06-15 |
US4394507A (en) | 1983-07-19 |
YU44035B (en) | 1990-02-28 |
IT8249608A0 (it) | 1982-12-02 |
ES530218A0 (es) | 1985-07-01 |
FI76561C (fi) | 1988-11-10 |
GR77107B (ko) | 1984-09-06 |
ES8405767A1 (es) | 1984-06-16 |
PT75980A (en) | 1983-01-01 |
JPS58105963A (ja) | 1983-06-24 |
FI76561B (fi) | 1988-07-29 |
SE8207112L (sv) | 1983-06-15 |
AT378182B (de) | 1985-06-25 |
IT1149399B (it) | 1986-12-03 |
PT75980B (en) | 1985-12-20 |
NL8204775A (nl) | 1983-07-01 |
KR890000419B1 (ko) | 1989-03-17 |
FI824234A0 (fi) | 1982-12-09 |
HU186190B (en) | 1985-06-28 |
DK551582A (da) | 1983-06-15 |
ES517996A0 (es) | 1984-06-16 |
DK156648C (da) | 1990-03-05 |
JPS6058231B2 (ja) | 1985-12-19 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2007082131A1 (en) | Process for the preparation of hydroxy substituted heterocycles | |
Bradsher et al. | The reaction of amines with 1-phenacyl-2-bromopyridinium salts. A new route to imidazo [1, 2-. alpha.] pyridinium, oxazolo [3, 2-. alpha.] pyridinium, and dihydropyrido [2, 1-c]-as-triazinium salts | |
HRP20010747A2 (en) | Novel synthesis and crystallization of piperazine ring-containing compounds | |
SE454442B (sv) | Forfarande for framstellning av 4-metoxi-2'-(2-(1-metyl-2-piperidyl)etyl)-bensamid(enkainid) och 2-(2-pyridylacetyl)-p-anisanilid som mellanprodukt | |
DE60211303T2 (de) | Verfahren zur herstellung und zwischenprodukte von pyridin-2-yl-amin | |
JPS59130861A (ja) | アリ−ルスルホニルアゼチジン化合物、それらの製造およびそれらの中間体としての使用 | |
US4031108A (en) | 2-Hydroxymethyl-3-benzyloxypyridine-6-epoxyethane | |
US6545149B2 (en) | Synthesis and crystallization of piperazine ring-containing compounds | |
US3948919A (en) | 2-Hydroxymethyl-3-hydroxy-6-(1-hydroxy-2-t-butylaminoethyl)pyridine preparation and intermediate compounds | |
DD202016A5 (de) | Kondensierte as-triazin-derivate | |
Mazaleyrat | Synthesis and resolution of axially chiral C2-symmetric 1, 1′-binaphthyl-substituted tetramethylethylenediamines | |
HU180514B (hu) | Eljárás apovinkaminsav-észterek, illetve vinkaminsav-észterek és apovinkaminsavészterek egyidejű előállítására | |
Ariga et al. | Ring Transformation of 1-Substituted 3, 5-Dinitro-4-pyridones to 4-Nitro-5 (2 H)-isoxazolone by Hydroxylamine | |
CN110452139B (zh) | 一种2-甲基-3-溴-6-甲砜基苯腈的制备方法 | |
US4454324A (en) | Process for production of encainide | |
CN110483402B (zh) | 一种3-溴-5-苯基-1h-吡唑的合成方法 | |
Nagarajan et al. | Synthesis and reactions of 4, 6, 7, 8-tetrahydro-5 (1H)-cinnolinones | |
CN111302997B (zh) | “一锅法”制备拉罗替尼中间体的方法 | |
JPH04243875A (ja) | 2−フェニル−6−(ピリミジン−2−イル)ピリジン化合物の製造方法、中間体化合物及び中間体化合物の製造方法 | |
DE2722043A1 (de) | Verfahren zur herstellung von 1-phenyl-2,3,4,5-tetrahydro-1h-3-benzazepin-derivaten | |
KR950005737B1 (ko) | 징코라이드 혼합물로부터 단성분의 분리방법 | |
Weis et al. | Dihydropyrimidines. 7. Synthesis and crystal structure of 2, 4-diaza-6, 7-benzo-8-oxabicyclo-[3.3. 1]-nonenes | |
US3994903A (en) | Preparation of 4-(3-nitrophenyl)pyridine | |
CN118206501A (zh) | 一种卢吗哌酮的制备方法 | |
Barbry et al. | Study of the transformation products of the oxime of 2, 7‐dioxo‐3‐methyl‐5‐phenyl‐2, 3, 5, 6‐tetrahydrocyclopenta [f] benzoxazole |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
NUG | Patent has lapsed |
Ref document number: 8207112-7 Effective date: 19940710 Format of ref document f/p: F |