SE446740B - Forfarande for framstellning av muramyldipeptidderivat - Google Patents
Forfarande for framstellning av muramyldipeptidderivatInfo
- Publication number
- SE446740B SE446740B SE7707276A SE7707276A SE446740B SE 446740 B SE446740 B SE 446740B SE 7707276 A SE7707276 A SE 7707276A SE 7707276 A SE7707276 A SE 7707276A SE 446740 B SE446740 B SE 446740B
- Authority
- SE
- Sweden
- Prior art keywords
- preparing
- procedure
- muramyldipeptide derivatives
- muramyldipeptide
- derivatives
- Prior art date
Links
- BSOQXXWZTUDTEL-ZUYCGGNHSA-N muramyl dipeptide Chemical class OC(=O)CC[C@H](C(N)=O)NC(=O)[C@H](C)NC(=O)[C@@H](C)O[C@H]1[C@H](O)[C@@H](CO)O[C@@H](O)[C@@H]1NC(C)=O BSOQXXWZTUDTEL-ZUYCGGNHSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
- C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
- C07K9/005—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Crystallography & Structural Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP7407276A JPS5914038B2 (ja) | 1976-06-23 | 1976-06-23 | 新規ムラミルジペプチド誘導体 |
| JP51150328A JPS6033119B2 (ja) | 1976-12-16 | 1976-12-16 | 新規ムラミルジペプチド誘導体 |
| JP1112277A JPS5398922A (en) | 1977-02-03 | 1977-02-03 | Novel melamyldipeptide derivative |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE7707276L SE7707276L (sv) | 1978-02-10 |
| SE446740B true SE446740B (sv) | 1986-10-06 |
Family
ID=27279285
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7707276A SE446740B (sv) | 1976-06-23 | 1977-06-22 | Forfarande for framstellning av muramyldipeptidderivat |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4101536A (en:Method) |
| CA (1) | CA1105005A (en:Method) |
| CH (1) | CH624124A5 (en:Method) |
| DE (1) | DE2728324A1 (en:Method) |
| FR (1) | FR2375249A1 (en:Method) |
| GB (1) | GB1563561A (en:Method) |
| NL (1) | NL171063C (en:Method) |
| SE (1) | SE446740B (en:Method) |
| SU (1) | SU793384A3 (en:Method) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU727647A1 (ru) * | 1977-11-02 | 1980-04-15 | Институт биоорганической химии им.М.М.Шемякина | Гликопептиды,обладающие противоопухолевой активностью и способ их получени |
| US4397844A (en) * | 1978-02-24 | 1983-08-09 | Ciba-Geigy Corporation | Antigen derivatives and processes for their preparation |
| JPS5543030A (en) * | 1978-09-21 | 1980-03-26 | Dai Ichi Seiyaku Co Ltd | Prophylactic and remedy for microbial infection disease |
| DE2965017D1 (en) * | 1978-12-22 | 1983-04-14 | Anvar | New compounds associating peptidyl or aminoacyl residues to lipophilic groups and pharmaceutical compositions containing said new compounds |
| FR2449697A1 (fr) | 1979-02-20 | 1980-09-19 | Anvar | Nouveaux muramyl-peptides substitues sur un azote peptidique et medicaments les contenant |
| JPS55111499A (en) * | 1979-02-21 | 1980-08-28 | Takeda Chem Ind Ltd | Glucosamine derivative and its preparation |
| US4391800A (en) * | 1979-04-27 | 1983-07-05 | Merck & Co., Inc. | Immunologically active peptidyl disaccharides and methods of preparation |
| FI75578C (fi) * | 1979-07-25 | 1988-07-11 | Ciba Geigy Ag | Analogifoerfarande foer framstaellning av farmakologiskt verkande lipofila fosfatidylmuramylpeptider. |
| US4406889A (en) * | 1980-02-15 | 1983-09-27 | Ciba-Geigy Corporation | Derivatives of aldohexoses, intermediates, processes for their manufacture, preparations containing such compounds, and their use |
| US4340588A (en) * | 1980-03-28 | 1982-07-20 | Research Corporation | Brucellosis vaccine for cattle containing mycolate esters of trehalose |
| US4310514A (en) * | 1980-05-05 | 1982-01-12 | Merck & Co., Inc. | Immunologically active dipeptidyl 5-0,6-0-acyl-2-amino-2-deoxy-D-glucofuranose derivatives and methods of preparation |
| US4315913A (en) * | 1980-06-09 | 1982-02-16 | Merck & Co. Inc. | Immunologically active dipeptidyl 2-amino-1,2-dideoxy-D-glucose derivatives and methods of preparation |
| GR78246B (en:Method) * | 1981-01-23 | 1984-09-26 | Ciba Geigy Ag | |
| JPS5920297A (ja) * | 1982-07-27 | 1984-02-01 | Dai Ichi Seiyaku Co Ltd | ムラミルジペプチド誘導体 |
| US4606918A (en) * | 1983-08-22 | 1986-08-19 | Syntex (U.S.A.) Inc. | Polyoxypropylene-polyoxyethylene block polymer based adjuvants |
| US4933179A (en) * | 1983-08-22 | 1990-06-12 | Syntex (U.S.A.) Inc. | Feline leukemia virus antigen vaccines |
| US4770874A (en) * | 1983-08-22 | 1988-09-13 | Syntex (U.S.A.) Inc. | Polyoxypropylene-polyoxyethylene block polymer based adjuvants |
| US4772466A (en) * | 1983-08-22 | 1988-09-20 | Syntex (U.S.A.) Inc. | Vaccines comprising polyoxypropylene-polyoxyethylene block polymer based adjuvants |
| FR2564096B1 (fr) * | 1984-05-11 | 1988-02-19 | Anvar | Derives lipophiles de muramylpeptides ayant des proprietes d'activation des macrophages, compositions les contenant et procede pour les obtenir |
| DK585886A (da) * | 1985-12-24 | 1987-06-25 | Takeda Chemical Industries Ltd | Immunstimulerende middel og anvendelse deraf |
| US5554372A (en) * | 1986-09-22 | 1996-09-10 | Emory University | Methods and vaccines comprising surface-active copolymers |
| US4895835A (en) * | 1987-11-20 | 1990-01-23 | Nisshin Oil Mills, Ltd. | Muramyl peptide derivatives and use thereof |
| US5149529A (en) * | 1988-04-08 | 1992-09-22 | Board Of Trustees Of Leland Chiron Corporation | Compositions and treatment for herpes simplex |
| US5416070A (en) * | 1988-07-08 | 1995-05-16 | Immunotherapeutics, Inc. | Composition for macrophage activation |
| US4950645A (en) * | 1988-07-08 | 1990-08-21 | Immunotherapeutics, Inc. | Composition for macrophage activation |
| DE3840538A1 (de) * | 1988-12-01 | 1990-06-07 | Helopharm Petrik Co Kg | Peptidoglucan-dimere, verfahren zu ihrer herstellung und ihre verwendung als immunmodulatoren |
| GB9320820D0 (en) * | 1993-10-08 | 1993-12-01 | Biokine Tech Ltd | Compounds for medicinal use |
| US6156319A (en) | 1994-07-25 | 2000-12-05 | The Trustees Of The University Of Pennsylvania | Soluble herpesvirus glycoprotein complex vaccine |
| AU4251300A (en) | 1999-05-07 | 2000-11-21 | University Of Virginia Patent Foundation | Biological production of stable glutamine, poly-glutamine derivatives in transgenic organisms and their use for therapeutic purposes |
| EP1670508B1 (en) | 2003-02-28 | 2012-10-24 | Trustees Of The University Of Pennsylvania | Compositions, methods and kits relating to poxvirus subunit vaccines |
| WO2006112869A2 (en) * | 2004-07-19 | 2006-10-26 | Baylor College Of Medicine | Modulation of cytokine signaling regulators and applications for immunotherapy |
| KR101203401B1 (ko) * | 2005-06-08 | 2012-11-22 | 이쉥 바이오파마(싱가포르)피티이 리미티드 | 폴리이노신산-폴리시티딜산-기초 보조제 |
| US7868159B2 (en) * | 2005-06-23 | 2011-01-11 | Baylor College Of Medicine | Modulation of negative immune regulators and applications for immunotherapy |
| US20070166239A1 (en) * | 2006-01-13 | 2007-07-19 | Haixiang Lin | Mucosal immunogenic substances comprising a polyinosinic acid - polycytidilic acid based adjuvant |
| US20070166800A1 (en) * | 2006-01-13 | 2007-07-19 | Haixiang Lin | Immunogenic substances comprising a polyinosinic acid-polycytidilic acid based adjuvant |
| EP2136832B1 (en) | 2007-03-26 | 2015-09-02 | General Regeneratives Limited | Methods for promoting protection and regeneration of bone marrow using cxcl9 and anti-cxcl9 antibodies |
| WO2009082593A2 (en) * | 2007-11-30 | 2009-07-02 | Baylor College Of Medicine | Dendritic cell vaccine compositions and uses of same |
| US9808504B2 (en) | 2009-09-22 | 2017-11-07 | Yale University | Immunogenic epitopes as targets for universal cancer vaccines |
| CA2846486C (en) | 2011-07-12 | 2019-08-20 | Philadelphia Health & Education Corporation | Novel clostridium difficile dna vaccine |
| WO2015116178A1 (en) | 2014-01-31 | 2015-08-06 | Thomas Jefferson University | Fusion proteins for modulating regulatory and effector t cells |
| EP2951199A4 (en) | 2013-01-31 | 2016-07-20 | Univ Jefferson | Fusion proteins for the modulation of regulatory and effector T cells |
| WO2016105274A1 (en) | 2014-12-23 | 2016-06-30 | Yisheng Biopharma (Singapore) Pte Ltd | A rabies composition comprising pika adjuvant |
| WO2016138286A1 (en) | 2015-02-26 | 2016-09-01 | Stc.Unm | Irgm and precision autophagy controls for antimicrobial and inflammatory disease states and methods of detection of autophagy |
| WO2020140007A1 (en) | 2018-12-28 | 2020-07-02 | University Of Rochester | Gene therapy for best1 dominant mutations |
| WO2025096754A1 (en) | 2023-10-31 | 2025-05-08 | Musc Foundation For Research Development | The use of enolase inhibitor pomhex for treatment of fibrosis |
-
1977
- 1977-06-21 GB GB25942/77A patent/GB1563561A/en not_active Expired
- 1977-06-22 SE SE7707276A patent/SE446740B/xx not_active IP Right Cessation
- 1977-06-22 SU SU772497271A patent/SU793384A3/ru active
- 1977-06-23 US US05/809,245 patent/US4101536A/en not_active Expired - Lifetime
- 1977-06-23 FR FR7719306A patent/FR2375249A1/fr active Granted
- 1977-06-23 DE DE19772728324 patent/DE2728324A1/de active Granted
- 1977-06-23 NL NLAANVRAGE7706948,A patent/NL171063C/xx not_active IP Right Cessation
- 1977-06-23 CH CH769177A patent/CH624124A5/fr not_active IP Right Cessation
- 1977-06-23 CA CA000281215A patent/CA1105005A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| CA1105005A (en) | 1981-07-14 |
| CH624124A5 (en:Method) | 1981-07-15 |
| FR2375249B1 (en:Method) | 1980-04-11 |
| NL171063B (nl) | 1982-09-01 |
| DE2728324C2 (en:Method) | 1988-07-07 |
| FR2375249A1 (fr) | 1978-07-21 |
| DE2728324A1 (de) | 1978-01-12 |
| NL7706948A (nl) | 1977-12-28 |
| US4101536A (en) | 1978-07-18 |
| SE7707276L (sv) | 1978-02-10 |
| SU793384A3 (ru) | 1980-12-30 |
| NL171063C (nl) | 1983-02-01 |
| GB1563561A (en) | 1980-03-26 |
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Legal Events
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| NAL | Patent in force |
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