SE446338B - 2-hydroximetyl-pyrazin-4-oxid-derivat, forfarande for framstellning derav samt farmaceutisk komposition innehallande dessa derivat - Google Patents
2-hydroximetyl-pyrazin-4-oxid-derivat, forfarande for framstellning derav samt farmaceutisk komposition innehallande dessa derivatInfo
- Publication number
- SE446338B SE446338B SE7902661A SE7902661A SE446338B SE 446338 B SE446338 B SE 446338B SE 7902661 A SE7902661 A SE 7902661A SE 7902661 A SE7902661 A SE 7902661A SE 446338 B SE446338 B SE 446338B
- Authority
- SE
- Sweden
- Prior art keywords
- pyrazinylmethyl
- compound
- formula
- pyrazine
- methyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/12—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/16—Halogen atoms; Nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/18—Oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/20—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT21520/78A IT1094287B (it) | 1978-03-23 | 1978-03-23 | Derivati della 2-idrossimetil-pirazina aventi attivita' ipolipemizzante |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE7902661L SE7902661L (sv) | 1979-09-24 |
| SE446338B true SE446338B (sv) | 1986-09-01 |
Family
ID=11183025
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7902661A SE446338B (sv) | 1978-03-23 | 1979-03-23 | 2-hydroximetyl-pyrazin-4-oxid-derivat, forfarande for framstellning derav samt farmaceutisk komposition innehallande dessa derivat |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US4267327A (fi) |
| JP (1) | JPS5531063A (fi) |
| BE (1) | BE875013A (fi) |
| CA (1) | CA1146171A (fi) |
| CH (1) | CH642639A5 (fi) |
| DE (1) | DE2910824A1 (fi) |
| DK (1) | DK151254C (fi) |
| FR (2) | FR2448536A1 (fi) |
| GB (1) | GB2017691B (fi) |
| IT (1) | IT1094287B (fi) |
| NL (1) | NL7902268A (fi) |
| SE (1) | SE446338B (fi) |
| ZA (1) | ZA791047B (fi) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4406901A (en) * | 1980-02-06 | 1983-09-27 | Farmitalia Carlo Erba S.P.A. | Ethers of substituted hydroxymethylpyrazines |
| IL64267A (en) * | 1980-12-09 | 1985-08-30 | Erba Farmitalia | Ethers of hydroxymethylpyrazin-n-oxides,their preparation and pharmaceutical compositions containing them |
| JPS59219269A (ja) * | 1983-05-30 | 1984-12-10 | Terumo Corp | ピラジン誘導体を有効成分とする血小板凝集抑制剤 |
| DE3433960A1 (de) * | 1984-09-15 | 1986-03-27 | Basf Ag, 6700 Ludwigshafen | Verfahren zur herstellung von 2-amino-3-cyano-5-dialkoxymehtyl-pyrazinen und zwischenprodukte fuer diese verfahren |
| JPS63135216U (fi) * | 1987-02-27 | 1988-09-05 | ||
| CN101684102B (zh) * | 2008-09-28 | 2013-06-05 | 安徽省新星药物开发有限责任公司 | 苯氧乙酸吡嗪酯类衍生物及其制法和用途 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU470007B2 (en) * | 1972-04-28 | 1976-02-26 | Farmitalia Carlo Erba S.R.L. | Pyrazine 4-oxide derivatives and process for their preparation |
| US4002750A (en) * | 1972-04-28 | 1977-01-11 | Carlo Erba S.P.A. | Pyrazine 4-oxide derivatives and process for their preparation |
| US4051245A (en) * | 1972-04-28 | 1977-09-27 | Carlo Erba, S.P.A. | Pyrazine 4-oxide derivatives and process for their preparation |
-
1978
- 1978-03-23 IT IT21520/78A patent/IT1094287B/it active
-
1979
- 1979-02-26 US US06/015,223 patent/US4267327A/en not_active Expired - Lifetime
- 1979-03-06 ZA ZA791047A patent/ZA791047B/xx unknown
- 1979-03-20 DE DE19792910824 patent/DE2910824A1/de active Granted
- 1979-03-20 CH CH261779A patent/CH642639A5/de not_active IP Right Cessation
- 1979-03-21 GB GB7909897A patent/GB2017691B/en not_active Expired
- 1979-03-22 NL NL7902268A patent/NL7902268A/xx not_active Application Discontinuation
- 1979-03-22 DK DK118879A patent/DK151254C/da not_active IP Right Cessation
- 1979-03-22 BE BE0/194146A patent/BE875013A/xx not_active IP Right Cessation
- 1979-03-22 CA CA000323983A patent/CA1146171A/en not_active Expired
- 1979-03-23 JP JP3340479A patent/JPS5531063A/ja active Granted
- 1979-03-23 FR FR7907433A patent/FR2448536A1/fr active Granted
- 1979-03-23 SE SE7902661A patent/SE446338B/sv not_active IP Right Cessation
-
1980
- 1980-02-27 FR FR8004355A patent/FR2445144A1/fr active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| FR2448536A1 (fr) | 1980-09-05 |
| FR2448536B1 (fi) | 1983-01-28 |
| FR2445144B1 (fi) | 1983-03-25 |
| BE875013A (fr) | 1979-09-24 |
| FR2445144A1 (fr) | 1980-07-25 |
| DK118879A (da) | 1979-09-24 |
| DK151254B (da) | 1987-11-16 |
| DK151254C (da) | 1988-07-04 |
| ZA791047B (en) | 1980-03-26 |
| CH642639A5 (de) | 1984-04-30 |
| NL7902268A (nl) | 1979-09-25 |
| JPS6310697B2 (fi) | 1988-03-08 |
| GB2017691A (en) | 1979-10-10 |
| GB2017691B (en) | 1982-06-16 |
| DE2910824C2 (fi) | 1989-06-22 |
| US4267327A (en) | 1981-05-12 |
| CA1146171A (en) | 1983-05-10 |
| DE2910824A1 (de) | 1979-09-27 |
| SE7902661L (sv) | 1979-09-24 |
| IT7821520A0 (it) | 1978-03-23 |
| IT1094287B (it) | 1985-07-26 |
| JPS5531063A (en) | 1980-03-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NUG | Patent has lapsed |
Ref document number: 7902661-3 Effective date: 19921005 Format of ref document f/p: F |