SE424994B - Forfarande for framstellning av nya pseudotrisackarider - Google Patents

Forfarande for framstellning av nya pseudotrisackarider

Info

Publication number
SE424994B
SE424994B SE7409946A SE7409946A SE424994B SE 424994 B SE424994 B SE 424994B SE 7409946 A SE7409946 A SE 7409946A SE 7409946 A SE7409946 A SE 7409946A SE 424994 B SE424994 B SE 424994B
Authority
SE
Sweden
Prior art keywords
pseudotrisaccarides
procedure
preparation
new
new pseudotrisaccarides
Prior art date
Application number
SE7409946A
Other languages
English (en)
Swedish (sv)
Other versions
SE7409946L (xx
Inventor
M J Weinstein
P J L Daniels
G H Wagman
R Testa
A K Mallams
J J Wright
T L Nagabhushan
Original Assignee
Scherico Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/452,586 external-priority patent/US4029882A/en
Application filed by Scherico Ltd filed Critical Scherico Ltd
Publication of SE7409946L publication Critical patent/SE7409946L/xx
Publication of SE424994B publication Critical patent/SE424994B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • C07H15/236—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2 a saccharide radical being substituted by an alkylamino radical in position 3 and by two substituents different from hydrogen in position 4, e.g. gentamicin complex, sisomicin, verdamycin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
SE7409946A 1973-08-06 1974-08-01 Forfarande for framstellning av nya pseudotrisackarider SE424994B (sv)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US38575173A 1973-08-06 1973-08-06
US45260074A 1974-03-19 1974-03-19
US05/452,586 US4029882A (en) 1974-03-19 1974-03-19 Selective acylation of the C-1 amino group of aminoglycoside antibiotics

Publications (2)

Publication Number Publication Date
SE7409946L SE7409946L (xx) 1975-02-07
SE424994B true SE424994B (sv) 1982-08-23

Family

ID=27409729

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7409946A SE424994B (sv) 1973-08-06 1974-08-01 Forfarande for framstellning av nya pseudotrisackarider

Country Status (20)

Country Link
AR (1) AR215834A1 (xx)
BE (1) BE818431A (xx)
BG (1) BG25804A3 (xx)
CH (1) CH606076A5 (xx)
CY (1) CY1018A (xx)
DD (1) DD119037A5 (xx)
DE (2) DE2462485A1 (xx)
DK (1) DK146298C (xx)
FI (1) FI62100C (xx)
FR (1) FR2240015B1 (xx)
GB (1) GB1473733A (xx)
HK (1) HK55179A (xx)
IE (1) IE40437B1 (xx)
IL (1) IL45385A (xx)
KE (1) KE2981A (xx)
LU (1) LU70661A1 (xx)
MY (1) MY8000090A (xx)
NL (1) NL171587C (xx)
NO (1) NO139483C (xx)
SE (1) SE424994B (xx)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4217446A (en) 1974-10-26 1980-08-12 Pfizer Inc. ωAmino-2-hydroxyalkyl derivatives of aminoglycoside antibiotics
GB1464401A (en) * 1974-10-26 1977-02-16 Pfizer Ltd Aminoglycosides
FR2405266A1 (fr) * 1975-09-08 1979-05-04 Scherico Ltd Nouveaux pseudotrisaccharides, et applications pharmaceutiques de ceux-ci
DE2861947D1 (en) * 1977-06-10 1982-09-02 Bayer Ag Selectively protected 4,6-di-o-(aminoglycosyl)-1,3-diamino-cyclitols
US4282350A (en) * 1977-08-05 1981-08-04 Schering Corporation Selective 3"-N-acylation of 1,3"-di-N-unprotected-poly-N-protected-4,6-di-O-(aminoglycosyl)-1,3-diaminocyclitols
JPS5492951A (en) * 1977-12-29 1979-07-23 Shionogi & Co Ltd Novel aminoglycoside derivative
JPS5538345A (en) * 1978-09-11 1980-03-17 Shionogi & Co Ltd Novel aminoglycoside derivative
DE2840907A1 (de) * 1978-09-20 1980-04-03 Bayer Ag Selektiv geschuetzte 4,6-di-o-(aminoglykosyl)-1,3-diaminocyclitole
DE2928183A1 (de) * 1979-07-12 1981-01-29 Bayer Ag 1-n-alkylsisomicin-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
CN1040177C (zh) * 1993-04-23 1998-10-14 江苏省微生物研究所 一种含1-N-乙基庆大霉素C1a或其盐的药用制剂及制备方法
AU2008326297B2 (en) 2007-11-21 2012-11-08 Cipla USA, Inc. Antibacterial aminoglycoside analogs
WO2010132760A1 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial derivatives of tobramycin
WO2010132759A1 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial derivatives of dibekacin
WO2010132765A2 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial aminoglycoside analogs
WO2010132757A2 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial aminoglycoside analogs
WO2010132768A1 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial derivatives of sisomicin
CN101575311B (zh) * 2009-06-19 2011-05-04 无锡好芳德药业有限公司 一种制备褪黑素的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1235311B (de) * 1963-03-25 1967-03-02 Roussel Uclaf Verfahren zur Herstellung von N-Monophenylaethylneomycin B bzw. seinen therapeutisch vertraeglichen Salzen

Also Published As

Publication number Publication date
FI230474A (xx) 1975-02-07
DE2437160B2 (de) 1979-01-04
IL45385A0 (en) 1974-11-29
IE40437L (en) 1975-02-06
DE2437160A1 (de) 1975-02-20
BE818431A (fr) 1975-02-03
SE7409946L (xx) 1975-02-07
DE2462485C2 (xx) 1987-04-09
AR215834A1 (es) 1979-11-15
FI62100C (fi) 1982-11-10
FI62100B (fi) 1982-07-30
NO139483B (no) 1978-12-11
HK55179A (en) 1979-08-17
NO742787L (xx) 1975-03-03
IL45385A (en) 1978-10-31
CH606076A5 (xx) 1978-10-13
NL7410363A (nl) 1975-02-10
GB1473733A (en) 1977-05-18
FR2240015A1 (xx) 1975-03-07
KE2981A (en) 1979-07-20
AU7194274A (en) 1976-02-05
IE40437B1 (en) 1979-06-06
NL171587C (nl) 1983-04-18
LU70661A1 (xx) 1975-05-21
NO139483C (no) 1979-03-21
NL171587B (nl) 1982-11-16
DK146298C (da) 1984-02-06
FR2240015B1 (xx) 1978-08-18
BG25804A3 (en) 1978-12-12
DE2437160C3 (de) 1979-08-30
MY8000090A (en) 1980-12-31
DK146298B (da) 1983-08-29
DK412474A (xx) 1975-04-01
CY1018A (en) 1979-11-23
DD119037A5 (xx) 1976-04-05
DE2462485A1 (de) 1977-04-21

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