FR2405266A1 - Nouveaux pseudotrisaccharides, et applications pharmaceutiques de ceux-ci - Google Patents

Nouveaux pseudotrisaccharides, et applications pharmaceutiques de ceux-ci

Info

Publication number
FR2405266A1
FR2405266A1 FR7900540A FR7900540A FR2405266A1 FR 2405266 A1 FR2405266 A1 FR 2405266A1 FR 7900540 A FR7900540 A FR 7900540A FR 7900540 A FR7900540 A FR 7900540A FR 2405266 A1 FR2405266 A1 FR 2405266A1
Authority
FR
France
Prior art keywords
desoxystreptamines
epi
cpds
aminoglycosyl
desoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7900540A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scherico Ltd
Original Assignee
Scherico Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/611,290 external-priority patent/US4000262A/en
Priority claimed from US05/611,289 external-priority patent/US4000261A/en
Application filed by Scherico Ltd filed Critical Scherico Ltd
Publication of FR2405266A1 publication Critical patent/FR2405266A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • C07H15/236—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2 a saccharide radical being substituted by an alkylamino radical in position 3 and by two substituents different from hydrogen in position 4, e.g. gentamicin complex, sisomicin, verdamycin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

La présente invention concerne le domaine dés dérivés des (4,6)di-0-(aminoglycosyl)-2-désoxystreptamines. Ce sont les dérivés dans lesquels le groupement 2-désoxystreptamine est de formule :
FR7900540A 1975-09-08 1979-01-10 Nouveaux pseudotrisaccharides, et applications pharmaceutiques de ceux-ci Withdrawn FR2405266A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/611,290 US4000262A (en) 1974-11-29 1975-09-08 5-epi-amino and 5-epi-azido-4,6-di-o-(aminoglycosyl)-2,5-dideoxystreptamines 1-n-alkyl-5-epi-amino and 1-n-alkyl-5-epi-azido-4,6-di-o-(aminoglycosyl)-2,5-dideoxystreptamines
US05/611,289 US4000261A (en) 1974-11-29 1975-09-08 5-epi-4,6-di-o-(aminoglycosyl)-2-deoxystreptamines, methods for their manufacture and intermediates useful therein, methods for their use as antibacterial agents and compositions useful therefor

Publications (1)

Publication Number Publication Date
FR2405266A1 true FR2405266A1 (fr) 1979-05-04

Family

ID=27086483

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7900540A Withdrawn FR2405266A1 (fr) 1975-09-08 1979-01-10 Nouveaux pseudotrisaccharides, et applications pharmaceutiques de ceux-ci

Country Status (2)

Country Link
FR (1) FR2405266A1 (fr)
IL (1) IL56450A0 (fr)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2240015A1 (fr) * 1973-08-06 1975-03-07 Scherico Ltd

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2240015A1 (fr) * 1973-08-06 1975-03-07 Scherico Ltd

Also Published As

Publication number Publication date
IL56450A0 (en) 1979-03-12

Similar Documents

Publication Publication Date Title
ES468475A1 (es) Procedimiento para la preparacion de derivados de cefem
ES467964A1 (es) Procedimiento para la obtencion de derivados de los pseudo- trisacaridos.
BR9813319A (pt) Composto, composição farmacêutica para tratamento de infecções bacterianas, e, processos para tratar infecções bacterianas e para preparar um composto
BR9912375A (pt) Sais de nitrato, composições farmacêuticas, uso de sais e composições, e, processo para preparação de sais de nitrato.
GB1494129A (en) Derivatives of diaminocyclitols and methods for their preparation
FR2405266A1 (fr) Nouveaux pseudotrisaccharides, et applications pharmaceutiques de ceux-ci
CH608022A5 (en) Process for the preparation of halogenated aminoglycoside antibiotics and the use thereof
GB1506664A (en) Antiviral compositions
GB1444733A (en) Gentlamicin derivatives and process for their production
JPS5540621A (en) Novel aminoglycoside derivative
IL84861A (en) Nasal pharmaceutical composition comprising human calcitonin and viscosity-increasing swelling agent
FR2305190A1 (fr) Nouveaux medicaments anti-bacteriens a base de pseudotrisaccharides et leur procede d'obtention
GB1426910A (en) 3-deoxy derivatives of neamine and its related aminoglycosidic antibiotics and the production thereof
ES2194899T3 (es) Composicion farmaceutica para administracion transdermica sistemica del principio activo morfina-6-glucuronido.
IE810453L (en) Pharmaceutical adjuvant
ES8202561A1 (es) Un procedimiento para la produccion de 11,12-carbonato de eritromicilamina
IE43125L (en) Aminoglycoside derivative
FR2264558A1 (en) Polymixin-methyl tetracycline salt antibiotics - active against Gram positive and negative bacteria, viruses and protozoa
SE7513330L (sv) Pseudotrisackarider och forfarande for framstellning derav
HUP0102412A2 (hu) 2"-Dezoxi-higromicin-származékok
Sato Histopathological Study on the Vestibular Toxicity of Six Aminoglycoside Antibiotics.
ES8205809A1 (es) Un procedimiento para la preparacion de derivados de metoxi-cefalosporinas
JPS55329A (en) Novel xk-62-4 derivative
GB1499041A (en) Derivatives of kanamycin
JPS5681598A (en) Gentamicin derivative

Legal Events

Date Code Title Description
ST Notification of lapse