SE422579B - Forfarande for framstellning av 4-oxo-hexahydro-pyrazino(2,1-a)isokinolinderivat - Google Patents

Forfarande for framstellning av 4-oxo-hexahydro-pyrazino(2,1-a)isokinolinderivat

Info

Publication number
SE422579B
SE422579B SE7602535A SE7602535A SE422579B SE 422579 B SE422579 B SE 422579B SE 7602535 A SE7602535 A SE 7602535A SE 7602535 A SE7602535 A SE 7602535A SE 422579 B SE422579 B SE 422579B
Authority
SE
Sweden
Prior art keywords
isoqinoline
pyrazino
hexahydro
oxo
derivatives
Prior art date
Application number
SE7602535A
Other languages
English (en)
Swedish (sv)
Other versions
SE7602535L (sv
Inventor
R Pohlke
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of SE7602535L publication Critical patent/SE7602535L/xx
Publication of SE422579B publication Critical patent/SE422579B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/06Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with the ring nitrogen atom acylated by carboxylic or carbonic acids, or with sulfur or nitrogen analogues thereof, e.g. carbamates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE7602535A 1975-03-01 1976-02-26 Forfarande for framstellning av 4-oxo-hexahydro-pyrazino(2,1-a)isokinolinderivat SE422579B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2508947A DE2508947C3 (de) 1975-03-01 1975-03-01 Verfahren zur Herstellung von 4-Oxo-1,2,3,6,7, 11b-hexahydro-4H-pyrazino [2,1-a] isochinolinen

Publications (2)

Publication Number Publication Date
SE7602535L SE7602535L (sv) 1976-09-02
SE422579B true SE422579B (sv) 1982-03-15

Family

ID=5940184

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7602535A SE422579B (sv) 1975-03-01 1976-02-26 Forfarande for framstellning av 4-oxo-hexahydro-pyrazino(2,1-a)isokinolinderivat

Country Status (19)

Country Link
US (1) US4049659A (fi)
JP (1) JPS5940155B2 (fi)
AT (1) AT358043B (fi)
BE (1) BE839004A (fi)
CA (1) CA1068701A (fi)
CH (1) CH602727A5 (fi)
CS (1) CS194236B2 (fi)
DE (1) DE2508947C3 (fi)
DK (1) DK137275C (fi)
ES (1) ES445591A1 (fi)
FI (1) FI60866C (fi)
FR (1) FR2303014A1 (fi)
GB (1) GB1495236A (fi)
HU (1) HU175127B (fi)
IE (1) IE42959B1 (fi)
LU (1) LU74448A1 (fi)
NL (1) NL186696C (fi)
SE (1) SE422579B (fi)
YU (1) YU50576A (fi)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4196291A (en) * 1973-12-17 1980-04-01 Merck Patent Gesellschaft Mit Beschraenkter Haftung 2-Acyl-4-oxo-pyrazino-isoquinoline derivatives and process for the preparation thereof
US4113867A (en) * 1973-12-17 1978-09-12 Merck Patent Gesellschaft Mit Beschrankter Haftung 2-acyl-4-oxo-pyrazino-isoquinoline derivatives and process for the preparation thereof
US4162319A (en) * 1974-08-28 1979-07-24 Merck Patent Gesellschaft Mit Beschrankter Haftung Ring substituted pyrazino-isoquinoline derivatives and their preparation
DE3916549C1 (fi) * 1989-05-20 1990-05-17 Daimler-Benz Aktiengesellschaft, 7000 Stuttgart, De
CN100503582C (zh) * 2005-03-01 2009-06-24 江苏工业学院 吡喹酮合成工艺
CN101691367B (zh) * 2009-08-31 2013-07-24 中国人民解放军第二军医大学 具有抗真菌活性的哌嗪并[2,1-a]异喹啉类化合物或其盐类
WO2012081035A2 (en) * 2010-12-13 2012-06-21 Sequent Scientific Limited A process for preparation of praziquantel
RU2671202C1 (ru) 2015-02-12 2018-10-30 Чжэцзян Хисун Фармасьютикал Ко., Лтд. Способ получения празиквантела и его промежуточных соединений

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2331713A1 (de) * 1973-06-22 1975-01-23 Merck Patent Gmbh Pyrazinoisochinolin-derivat

Also Published As

Publication number Publication date
DE2508947A1 (de) 1976-09-09
JPS51110600A (en) 1976-09-30
FR2303014A1 (fr) 1976-10-01
IE42959B1 (en) 1980-11-19
YU50576A (en) 1982-05-31
FR2303014B1 (fi) 1978-05-19
ATA147576A (de) 1980-01-15
NL186696C (nl) 1991-02-01
DE2508947B2 (de) 1981-05-07
CH602727A5 (fi) 1978-07-31
CA1068701A (en) 1979-12-25
FI60866B (fi) 1981-12-31
US4049659A (en) 1977-09-20
GB1495236A (en) 1977-12-14
IE42959L (en) 1976-09-01
SE7602535L (sv) 1976-09-02
AT358043B (de) 1980-08-11
BE839004A (fr) 1976-08-27
JPS5940155B2 (ja) 1984-09-28
CS194236B2 (en) 1979-11-30
NL186696B (nl) 1990-09-03
ES445591A1 (es) 1977-06-01
FI760519A (fi) 1976-09-02
HU175127B (hu) 1980-05-28
DK79476A (da) 1976-09-02
DK137275C (da) 1978-07-17
DK137275B (da) 1978-02-13
FI60866C (fi) 1982-04-13
DE2508947C3 (de) 1982-02-25
NL7602101A (nl) 1976-09-03
LU74448A1 (fi) 1977-09-12

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