CS194236B2 - Method of preparing derivatives of 4-oxo-hexahydro-4h-pyrazino-isoquinoline - Google Patents

Method of preparing derivatives of 4-oxo-hexahydro-4h-pyrazino-isoquinoline

Info

Publication number
CS194236B2
CS194236B2 CS761180A CS118076A CS194236B2 CS 194236 B2 CS194236 B2 CS 194236B2 CS 761180 A CS761180 A CS 761180A CS 118076 A CS118076 A CS 118076A CS 194236 B2 CS194236 B2 CS 194236B2
Authority
CS
Czechoslovakia
Prior art keywords
pyrazino
hexahydro
isoquinoline
oxo
preparing derivatives
Prior art date
Application number
CS761180A
Other languages
English (en)
Inventor
Rolf Pohlke
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of CS194236B2 publication Critical patent/CS194236B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/06—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with the ring nitrogen atom acylated by carboxylic or carbonic acids, or with sulfur or nitrogen analogues thereof, e.g. carbamates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CS761180A 1975-03-01 1976-02-23 Method of preparing derivatives of 4-oxo-hexahydro-4h-pyrazino-isoquinoline CS194236B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2508947A DE2508947C3 (de) 1975-03-01 1975-03-01 Verfahren zur Herstellung von 4-Oxo-1,2,3,6,7, 11b-hexahydro-4H-pyrazino [2,1-a] isochinolinen

Publications (1)

Publication Number Publication Date
CS194236B2 true CS194236B2 (en) 1979-11-30

Family

ID=5940184

Family Applications (1)

Application Number Title Priority Date Filing Date
CS761180A CS194236B2 (en) 1975-03-01 1976-02-23 Method of preparing derivatives of 4-oxo-hexahydro-4h-pyrazino-isoquinoline

Country Status (19)

Country Link
US (1) US4049659A (cs)
JP (1) JPS5940155B2 (cs)
AT (1) AT358043B (cs)
BE (1) BE839004A (cs)
CA (1) CA1068701A (cs)
CH (1) CH602727A5 (cs)
CS (1) CS194236B2 (cs)
DE (1) DE2508947C3 (cs)
DK (1) DK137275C (cs)
ES (1) ES445591A1 (cs)
FI (1) FI60866C (cs)
FR (1) FR2303014A1 (cs)
GB (1) GB1495236A (cs)
HU (1) HU175127B (cs)
IE (1) IE42959B1 (cs)
LU (1) LU74448A1 (cs)
NL (1) NL186696C (cs)
SE (1) SE422579B (cs)
YU (1) YU50576A (cs)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4196291A (en) * 1973-12-17 1980-04-01 Merck Patent Gesellschaft Mit Beschraenkter Haftung 2-Acyl-4-oxo-pyrazino-isoquinoline derivatives and process for the preparation thereof
US4141978A (en) * 1973-12-17 1979-02-27 Merck Patent Gesellschaft Mit Beschrankter Haftung 2-Acyl-4-oxo-pyrazino-isoquinoline derivatives and process for the preparation thereof
US4162319A (en) * 1974-08-28 1979-07-24 Merck Patent Gesellschaft Mit Beschrankter Haftung Ring substituted pyrazino-isoquinoline derivatives and their preparation
DE3916549C1 (cs) * 1989-05-20 1990-05-17 Daimler-Benz Aktiengesellschaft, 7000 Stuttgart, De
CN100503582C (zh) * 2005-03-01 2009-06-24 江苏工业学院 吡喹酮合成工艺
CN101691367B (zh) * 2009-08-31 2013-07-24 中国人民解放军第二军医大学 具有抗真菌活性的哌嗪并[2,1-a]异喹啉类化合物或其盐类
EP2651225A4 (en) 2010-12-13 2016-07-06 Sequent Scient Ltd PROCESS FOR PREPARING PRAZIQUANTEL
BR112017017066B1 (pt) 2015-02-12 2022-11-29 Zhejiang Hisun Pharmaceutical Co., Ltd. Processo para preparação para praziquantel, seus intermediários e seus processos de preparação

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2331713A1 (de) * 1973-06-22 1975-01-23 Merck Patent Gmbh Pyrazinoisochinolin-derivat

Also Published As

Publication number Publication date
NL7602101A (nl) 1976-09-03
DK137275B (da) 1978-02-13
YU50576A (en) 1982-05-31
SE422579B (sv) 1982-03-15
BE839004A (fr) 1976-08-27
ATA147576A (de) 1980-01-15
FR2303014B1 (cs) 1978-05-19
DE2508947A1 (de) 1976-09-09
DK79476A (da) 1976-09-02
FR2303014A1 (fr) 1976-10-01
DE2508947C3 (de) 1982-02-25
FI60866B (fi) 1981-12-31
SE7602535L (sv) 1976-09-02
FI760519A (cs) 1976-09-02
CH602727A5 (cs) 1978-07-31
FI60866C (fi) 1982-04-13
CA1068701A (en) 1979-12-25
JPS51110600A (en) 1976-09-30
DE2508947B2 (de) 1981-05-07
IE42959B1 (en) 1980-11-19
AT358043B (de) 1980-08-11
DK137275C (da) 1978-07-17
HU175127B (hu) 1980-05-28
GB1495236A (en) 1977-12-14
LU74448A1 (cs) 1977-09-12
NL186696C (nl) 1991-02-01
US4049659A (en) 1977-09-20
JPS5940155B2 (ja) 1984-09-28
ES445591A1 (es) 1977-06-01
NL186696B (nl) 1990-09-03
IE42959L (en) 1976-09-01

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