ES445591A1 - Procedimiento para la obtencion de derivados de 4-oxo-hexa- hidro-pirazi-noisoquinolina. - Google Patents

Procedimiento para la obtencion de derivados de 4-oxo-hexa- hidro-pirazi-noisoquinolina.

Info

Publication number
ES445591A1
ES445591A1 ES445591A ES445591A ES445591A1 ES 445591 A1 ES445591 A1 ES 445591A1 ES 445591 A ES445591 A ES 445591A ES 445591 A ES445591 A ES 445591A ES 445591 A1 ES445591 A1 ES 445591A1
Authority
ES
Spain
Prior art keywords
hexahydro
oxo
preparation
pyrazinoisoquinoline
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES445591A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Publication of ES445591A1 publication Critical patent/ES445591A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/06Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with the ring nitrogen atom acylated by carboxylic or carbonic acids, or with sulfur or nitrogen analogues thereof, e.g. carbamates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES445591A 1975-03-01 1976-02-27 Procedimiento para la obtencion de derivados de 4-oxo-hexa- hidro-pirazi-noisoquinolina. Expired ES445591A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2508947A DE2508947C3 (de) 1975-03-01 1975-03-01 Verfahren zur Herstellung von 4-Oxo-1,2,3,6,7, 11b-hexahydro-4H-pyrazino [2,1-a] isochinolinen

Publications (1)

Publication Number Publication Date
ES445591A1 true ES445591A1 (es) 1977-06-01

Family

ID=5940184

Family Applications (1)

Application Number Title Priority Date Filing Date
ES445591A Expired ES445591A1 (es) 1975-03-01 1976-02-27 Procedimiento para la obtencion de derivados de 4-oxo-hexa- hidro-pirazi-noisoquinolina.

Country Status (19)

Country Link
US (1) US4049659A (es)
JP (1) JPS5940155B2 (es)
AT (1) AT358043B (es)
BE (1) BE839004A (es)
CA (1) CA1068701A (es)
CH (1) CH602727A5 (es)
CS (1) CS194236B2 (es)
DE (1) DE2508947C3 (es)
DK (1) DK137275C (es)
ES (1) ES445591A1 (es)
FI (1) FI60866C (es)
FR (1) FR2303014A1 (es)
GB (1) GB1495236A (es)
HU (1) HU175127B (es)
IE (1) IE42959B1 (es)
LU (1) LU74448A1 (es)
NL (1) NL186696C (es)
SE (1) SE422579B (es)
YU (1) YU50576A (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4196291A (en) * 1973-12-17 1980-04-01 Merck Patent Gesellschaft Mit Beschraenkter Haftung 2-Acyl-4-oxo-pyrazino-isoquinoline derivatives and process for the preparation thereof
US4113867A (en) * 1973-12-17 1978-09-12 Merck Patent Gesellschaft Mit Beschrankter Haftung 2-acyl-4-oxo-pyrazino-isoquinoline derivatives and process for the preparation thereof
US4162319A (en) * 1974-08-28 1979-07-24 Merck Patent Gesellschaft Mit Beschrankter Haftung Ring substituted pyrazino-isoquinoline derivatives and their preparation
DE3916549C1 (es) * 1989-05-20 1990-05-17 Daimler-Benz Aktiengesellschaft, 7000 Stuttgart, De
CN100503582C (zh) * 2005-03-01 2009-06-24 江苏工业学院 吡喹酮合成工艺
CN101691367B (zh) * 2009-08-31 2013-07-24 中国人民解放军第二军医大学 具有抗真菌活性的哌嗪并[2,1-a]异喹啉类化合物或其盐类
WO2012081035A2 (en) * 2010-12-13 2012-06-21 Sequent Scientific Limited A process for preparation of praziquantel
RU2671202C1 (ru) 2015-02-12 2018-10-30 Чжэцзян Хисун Фармасьютикал Ко., Лтд. Способ получения празиквантела и его промежуточных соединений

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2331713A1 (de) * 1973-06-22 1975-01-23 Merck Patent Gmbh Pyrazinoisochinolin-derivat

Also Published As

Publication number Publication date
DE2508947A1 (de) 1976-09-09
JPS51110600A (en) 1976-09-30
FR2303014A1 (fr) 1976-10-01
IE42959B1 (en) 1980-11-19
YU50576A (en) 1982-05-31
FR2303014B1 (es) 1978-05-19
ATA147576A (de) 1980-01-15
NL186696C (nl) 1991-02-01
DE2508947B2 (de) 1981-05-07
CH602727A5 (es) 1978-07-31
CA1068701A (en) 1979-12-25
SE422579B (sv) 1982-03-15
FI60866B (fi) 1981-12-31
US4049659A (en) 1977-09-20
GB1495236A (en) 1977-12-14
IE42959L (en) 1976-09-01
SE7602535L (sv) 1976-09-02
AT358043B (de) 1980-08-11
BE839004A (fr) 1976-08-27
JPS5940155B2 (ja) 1984-09-28
CS194236B2 (en) 1979-11-30
NL186696B (nl) 1990-09-03
FI760519A (es) 1976-09-02
HU175127B (hu) 1980-05-28
DK79476A (da) 1976-09-02
DK137275C (da) 1978-07-17
DK137275B (da) 1978-02-13
FI60866C (fi) 1982-04-13
DE2508947C3 (de) 1982-02-25
NL7602101A (nl) 1976-09-03
LU74448A1 (es) 1977-09-12

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970226