SE420090B - Forfarande forframstellning av 9-hydroxi-19,20-dinorprostansyra samt vissa salter, estrar och amider derav - Google Patents

Forfarande forframstellning av 9-hydroxi-19,20-dinorprostansyra samt vissa salter, estrar och amider derav

Info

Publication number
SE420090B
SE420090B SE7508857A SE7508857A SE420090B SE 420090 B SE420090 B SE 420090B SE 7508857 A SE7508857 A SE 7508857A SE 7508857 A SE7508857 A SE 7508857A SE 420090 B SE420090 B SE 420090B
Authority
SE
Sweden
Prior art keywords
dinorprostanic
amides
hydroxy
esters
acid
Prior art date
Application number
SE7508857A
Other languages
English (en)
Swedish (sv)
Other versions
SE7508857L (sv
Inventor
U Valcavi
Original Assignee
Lorenzini Sas Inst Biochim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lorenzini Sas Inst Biochim filed Critical Lorenzini Sas Inst Biochim
Publication of SE7508857L publication Critical patent/SE7508857L/xx
Publication of SE420090B publication Critical patent/SE420090B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/38—Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0016—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0025—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/01—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups
    • C07C59/10—Polyhydroxy carboxylic acids
    • C07C59/105—Polyhydroxy carboxylic acids having five or more carbon atoms, e.g. aldonic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/185—Saturated compounds having only one carboxyl group and containing keto groups
SE7508857A 1974-08-07 1975-08-06 Forfarande forframstellning av 9-hydroxi-19,20-dinorprostansyra samt vissa salter, estrar och amider derav SE420090B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT26111/74A IT1060366B (it) 1974-08-07 1974-08-07 Acidi 19.20 bis nor prostanoici come composti ipolipemici

Publications (2)

Publication Number Publication Date
SE7508857L SE7508857L (sv) 1976-02-09
SE420090B true SE420090B (sv) 1981-09-14

Family

ID=11218654

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7508857A SE420090B (sv) 1974-08-07 1975-08-06 Forfarande forframstellning av 9-hydroxi-19,20-dinorprostansyra samt vissa salter, estrar och amider derav

Country Status (19)

Country Link
US (1) US4073938A (de)
JP (1) JPS5819675B2 (de)
AT (1) AT359214B (de)
BE (1) BE832229A (de)
CA (1) CA1084917A (de)
CS (1) CS188965B2 (de)
DD (1) DD121103A5 (de)
DE (1) DE2535343C2 (de)
DK (1) DK357975A (de)
ES (1) ES440055A1 (de)
FR (1) FR2283670A1 (de)
GB (1) GB1523355A (de)
IL (1) IL47761A (de)
IT (1) IT1060366B (de)
NL (1) NL178314C (de)
PH (1) PH14954A (de)
SE (1) SE420090B (de)
SU (1) SU794003A1 (de)
ZA (1) ZA754777B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4239778A (en) * 1978-09-12 1980-12-16 The University Of Illinois Foundation Azaprostanoic acid analogs and their use as inhibitors of platelet aggregation
US4374856A (en) * 1980-09-10 1983-02-22 The Upjohn Company Liver cytoprotection using PGE's
IT1190400B (it) * 1985-10-04 1988-02-16 Istituto Biochimico Italiano Derivati dell'acido 19,20-bis,nor-prostanoico ad attivita' antiulcera e anoressivca,procedimento per la loro preparazione e composizioni farmaceutiche
IT1205183B (it) * 1987-06-25 1989-03-15 Istituto Biochimico Italiano Derivati prostaglandinici,procedimenti per prepararli e composizioni farmaceutiche che li contengono
EP1597223B1 (de) * 2003-01-23 2017-02-22 Esperion Therapeutics Inc. Hydroxylverbindungen und zusammensetzungen zur cholesterinkontrolle und damit verwandten verwendungen

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1027118A (en) * 1972-04-03 1978-02-28 Martin J. Weiss 3-alkyl-2-(6-carboxyhexyl) cyclopentanones and esters and salts thereof

Also Published As

Publication number Publication date
NL178314C (nl) 1986-03-03
NL7509196A (nl) 1976-02-10
IT1060366B (it) 1982-07-10
BE832229A (fr) 1975-12-01
DD121103A5 (de) 1976-07-12
ES440055A1 (es) 1977-07-16
ZA754777B (en) 1976-07-28
JPS51125043A (en) 1976-11-01
FR2283670B1 (de) 1981-01-02
FR2283670A1 (fr) 1976-04-02
CS188965B2 (en) 1979-03-30
SU794003A1 (ru) 1981-01-07
DE2535343A1 (de) 1976-02-19
SE7508857L (sv) 1976-02-09
GB1523355A (en) 1978-08-31
DE2535343C2 (de) 1983-08-04
IL47761A (en) 1979-07-25
NL178314B (nl) 1985-10-01
ATA616275A (de) 1980-03-15
AT359214B (de) 1980-10-27
IL47761A0 (en) 1975-10-15
PH14954A (en) 1982-02-02
DK357975A (da) 1976-02-08
CA1084917A (en) 1980-09-02
JPS5819675B2 (ja) 1983-04-19
US4073938A (en) 1978-02-14

Similar Documents

Publication Publication Date Title
SE7612202L (sv) Nya aminobensoesyraamider och forfarande for framstellning av dessa.
SE409856B (sv) Cyklopropankarboxylsyraestrar med insekticid och akaricid verkan
IL39171A (en) Asymmetrical esters of 1,4-dihydropyridine 3,5-dicarboxylic acid derivatives,their production and their medicinal use
BE827794A (fr) Derives d'acides phenoxy-alcanoiques
FR2336126A1 (fr) Derives d'esters d'acide phenylacetique
IT1066768B (it) Preparazione di anidridi di acido carbossilico
SE417512B (sv) Forfarande for framstellning av substituerade furankarboxylsyror samt estrar och salter derav
TR18425A (tr) Amido karboniltiobarbitrueik asit tuerevleri ve bunlarin tuzlari bunlarin hazirlanmasina mahsus usul ve bunlarin insektisid akarisid ve fungisid olarak kullanilmalari
SE436353B (sv) Forfarande for framstellning av aminosyraestrar
SE7608861L (sv) Substituerade alfa-aryloxikarbonsyraestrar
TR18127A (tr) Pirimidin-tionotiifosforik asit esterler, bunlarin hazirlanmasina mahsus usul ve bunlarin ensektisitler ve akarisitler olarak kullanilmalari
SE420090B (sv) Forfarande forframstellning av 9-hydroxi-19,20-dinorprostansyra samt vissa salter, estrar och amider derav
SE7510329L (sv) Framstellning av 5-fluoro-2-metyl-1-(p-metylsultinylbensyliden)-indenyl-3-ettiksyra
SE431204B (sv) Forfarande for framstellning av n?722-naftalensulfonyl-l-argininestrar och -amider eller farmaceutiskt accepterbara syraadditionssalter derav
HU171662B (hu) Sposob poluchenija novykh, opticheski aktivnykh proizvodnykh apovinkaminola i ikh kislotnykh adduktov
GB1521903A (en) 2-hydroxy-3-(substituted aryl)-3-butenoic acid esters and their production
GB1521905A (en) 2-hydroxy-3-(substituted aryl)-3-butenoic acid esters and their production
IL47606A (en) 5-(2-hydroxypropoxy)-4-oxo-8-propyl-4h-1-benzopyran-2-carboxylic acid and salts, esters or amides thereof, their preparation and pharmaceutical compositons containing them
SE416728B (sv) Nya acylfenoxipropansulfosyror och salter derav
CS177530B1 (en) New nbeta-substituted derivatives of b-beta-aminoethyl-ergoline-i their salts and methods for the production thereof
TR18404A (tr) N-ditio -2- osforil-karbomik asit esterleri,bunlarin hazirlanisi icin usul ve bunlarin ensektisidler ve akarisidler olarak kuilanilmalari
SE7509897L (sv) Basiskt substituerade 3-sulfamoylbensoesyraderivat och forfarande for deras framstellning
AR211381Q (es) Procedimiento para la produccion de sericosido (d-glocupiranosido de acido sericico), acido sericico y esteres, sales y derivados etilasino-dialquilico
SE398882B (sv) Forfarande for framstellning av salter av aminosyror och polysvavelsyraestrar av naturliga glykopeptider
NO149661C (no) Fremgangsmaate for fremstilling av salter av n-substituerte karbaminsyrer

Legal Events

Date Code Title Description
NUG Patent has lapsed

Ref document number: 7508857-5

Effective date: 19900703

Format of ref document f/p: F