DK357975A - 19,20-bis-nor-prostansyrer som hypolipemiske forbindelser - Google Patents

19,20-bis-nor-prostansyrer som hypolipemiske forbindelser

Info

Publication number
DK357975A
DK357975A DK357975A DK357975A DK357975A DK 357975 A DK357975 A DK 357975A DK 357975 A DK357975 A DK 357975A DK 357975 A DK357975 A DK 357975A DK 357975 A DK357975 A DK 357975A
Authority
DK
Denmark
Prior art keywords
prostanic
bis
acids
hypolipemic
compounds
Prior art date
Application number
DK357975A
Other languages
English (en)
Inventor
U Valcavi
Original Assignee
Istituto Biochimico Biochimico
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Istituto Biochimico Biochimico filed Critical Istituto Biochimico Biochimico
Publication of DK357975A publication Critical patent/DK357975A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/38—Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0016—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0025—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/01—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups
    • C07C59/10—Polyhydroxy carboxylic acids
    • C07C59/105—Polyhydroxy carboxylic acids having five or more carbon atoms, e.g. aldonic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/185—Saturated compounds having only one carboxyl group and containing keto groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK357975A 1974-08-07 1975-08-06 19,20-bis-nor-prostansyrer som hypolipemiske forbindelser DK357975A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT26111/74A IT1060366B (it) 1974-08-07 1974-08-07 Acidi 19.20 bis nor prostanoici come composti ipolipemici

Publications (1)

Publication Number Publication Date
DK357975A true DK357975A (da) 1976-02-08

Family

ID=11218654

Family Applications (1)

Application Number Title Priority Date Filing Date
DK357975A DK357975A (da) 1974-08-07 1975-08-06 19,20-bis-nor-prostansyrer som hypolipemiske forbindelser

Country Status (19)

Country Link
US (1) US4073938A (da)
JP (1) JPS5819675B2 (da)
AT (1) AT359214B (da)
BE (1) BE832229A (da)
CA (1) CA1084917A (da)
CS (1) CS188965B2 (da)
DD (1) DD121103A5 (da)
DE (1) DE2535343C2 (da)
DK (1) DK357975A (da)
ES (1) ES440055A1 (da)
FR (1) FR2283670A1 (da)
GB (1) GB1523355A (da)
IL (1) IL47761A (da)
IT (1) IT1060366B (da)
NL (1) NL178314C (da)
PH (1) PH14954A (da)
SE (1) SE420090B (da)
SU (1) SU794003A1 (da)
ZA (1) ZA754777B (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4239778A (en) * 1978-09-12 1980-12-16 The University Of Illinois Foundation Azaprostanoic acid analogs and their use as inhibitors of platelet aggregation
US4374856A (en) * 1980-09-10 1983-02-22 The Upjohn Company Liver cytoprotection using PGE's
IT1190400B (it) * 1985-10-04 1988-02-16 Istituto Biochimico Italiano Derivati dell'acido 19,20-bis,nor-prostanoico ad attivita' antiulcera e anoressivca,procedimento per la loro preparazione e composizioni farmaceutiche
IT1205183B (it) * 1987-06-25 1989-03-15 Istituto Biochimico Italiano Derivati prostaglandinici,procedimenti per prepararli e composizioni farmaceutiche che li contengono
MXPA05007674A (es) * 2003-01-23 2005-09-22 Esperion Therapeutics Inc Compuestos de hidroxilo y composiciones para el manejo del colesterol y usos relacionados.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1027118A (en) * 1972-04-03 1978-02-28 Martin J. Weiss 3-alkyl-2-(6-carboxyhexyl) cyclopentanones and esters and salts thereof

Also Published As

Publication number Publication date
PH14954A (en) 1982-02-02
SU794003A1 (ru) 1981-01-07
ATA616275A (de) 1980-03-15
US4073938A (en) 1978-02-14
IT1060366B (it) 1982-07-10
DE2535343A1 (de) 1976-02-19
AT359214B (de) 1980-10-27
BE832229A (fr) 1975-12-01
JPS5819675B2 (ja) 1983-04-19
CS188965B2 (en) 1979-03-30
ZA754777B (en) 1976-07-28
DE2535343C2 (de) 1983-08-04
FR2283670A1 (fr) 1976-04-02
SE7508857L (sv) 1976-02-09
IL47761A0 (en) 1975-10-15
CA1084917A (en) 1980-09-02
NL7509196A (nl) 1976-02-10
ES440055A1 (es) 1977-07-16
SE420090B (sv) 1981-09-14
DD121103A5 (da) 1976-07-12
GB1523355A (en) 1978-08-31
NL178314B (nl) 1985-10-01
NL178314C (nl) 1986-03-03
IL47761A (en) 1979-07-25
FR2283670B1 (da) 1981-01-02
JPS51125043A (en) 1976-11-01

Similar Documents

Publication Publication Date Title
SE419644B (sv) Pyrazolforening tillanvendning som insekticid
NL7503553A (nl) 16-geoxygeneerde prostaanzuurderivaten.
SE413026B (sv) Substituerad pyrazol for anvendning som herbicid
NL7512893A (nl) Regelaarsamenstel.
NO134406C (no) Trinse for skistav.
SE7504326L (sv) Aryl-oxo-heptansyror.
SE426056B (sv) Stabiliserad 1,1,1-trikloretan
NL7510778A (nl) Polyeenverbindingen.
NL7504303A (nl) Prostaglandinepreparaten.
NL7505481A (nl) 13-thiaprostaanzuurderivaten.
OA05040A (fr) Nouvelle composition fongicide.
NL7500921A (nl) Aandrijving.
DK357975A (da) 19,20-bis-nor-prostansyrer som hypolipemiske forbindelser
BR7503239A (pt) Processo para a preparacao de 3-triclorometil-5-etoxi-1,2,4-tiadiazol
SE7506906L (sv) Trijodisoftalamsyror.
BR7501346A (pt) Processo para a preparacao de um composto de s-triazol-(3,4-b)-benzo-tiazol
SE411622B (sv) 2,4,6-trijod-5-metoxiacetamido-n-metylisoftalamsyraforeningar for anvendning sasom rontgenkotrastmedel
DK209275A (da) Fremgangsmade til fremstilling af 2,3-polymethylen-5-sulfamoylbenzoesyreforbindelser
SE7503928L (sv) 3beta-hydroxi-2-(substituerade 1-alkenyl)- 5-oxocyklopentan-1-heptansyror.
SE7505259L (sv) Klarningsforfarande for vetskor.
NL7513873A (nl) Prosteenzuurderivaten.
NL7502658A (nl) Polyeenverbindingen.
FR2296626A1 (fr) 2,6-methano-3-benzazocines
DK138266B (da) Analogifremgangsmåde til fremstilling af basiske derivater af 1-aryl-2-oxo-2,4,5,6,7,7a-hexahydroindoler eller syreadditionssalte deraf.
DK135948C (da) Insecticidt virksom o-alkyl-o-isobutyl-o-(2,2-dichlorvinyl)-thionophosphorsyreester

Legal Events

Date Code Title Description
AHB Application shelved due to non-payment