SE409855B - Forfarande for framstellning av hydroxisubstituerade bifenylylpropionsyror och derivat derav - Google Patents

Forfarande for framstellning av hydroxisubstituerade bifenylylpropionsyror och derivat derav

Info

Publication number
SE409855B
SE409855B SE7308350A SE7308350A SE409855B SE 409855 B SE409855 B SE 409855B SE 7308350 A SE7308350 A SE 7308350A SE 7308350 A SE7308350 A SE 7308350A SE 409855 B SE409855 B SE 409855B
Authority
SE
Sweden
Prior art keywords
hydroxis
biphenylylpropionic
derivatives
acids
substituted
Prior art date
Application number
SE7308350A
Other languages
English (en)
Swedish (sv)
Inventor
S S Adams
B J Armitage
J S Nicholson
Original Assignee
Boots Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boots Co Ltd filed Critical Boots Co Ltd
Publication of SE409855B publication Critical patent/SE409855B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/10—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D263/14—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/001—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by modification in a side chain
    • C07C37/002—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by modification in a side chain by transformation of a functional group, e.g. oxo, carboxyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/24—Halogenated derivatives
    • C07C39/367—Halogenated derivatives polycyclic non-condensed, containing only six-membered aromatic rings as cyclic parts, e.g. halogenated poly-hydroxyphenylalkanes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/64—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of functional groups containing oxygen only in singly bound form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/65—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/277—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/82—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
    • C07C49/83—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/52—Unsaturated compounds containing hydroxy or O-metal groups a hydroxy or O-metal group being bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/56—Unsaturated compounds containing hydroxy or O-metal groups containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE7308350A 1972-06-15 1973-06-13 Forfarande for framstellning av hydroxisubstituerade bifenylylpropionsyror och derivat derav SE409855B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2810472A GB1396726A (en) 1972-06-15 1972-06-15 Phenylalkanoic acids

Publications (1)

Publication Number Publication Date
SE409855B true SE409855B (sv) 1979-09-10

Family

ID=10270338

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7308350A SE409855B (sv) 1972-06-15 1973-06-13 Forfarande for framstellning av hydroxisubstituerade bifenylylpropionsyror och derivat derav

Country Status (26)

Country Link
US (1) US3969402A (ja)
JP (1) JPS4961144A (ja)
AR (1) AR211760A1 (ja)
AT (1) AT329036B (ja)
BE (1) BE800951A (ja)
CA (1) CA1012151A (ja)
CH (1) CH584180A5 (ja)
CS (1) CS176239B2 (ja)
DD (1) DD108977A5 (ja)
DE (1) DE2329125A1 (ja)
ES (1) ES415919A1 (ja)
FI (1) FI57929C (ja)
FR (1) FR2189036B1 (ja)
GB (1) GB1396726A (ja)
HU (1) HU167229B (ja)
IE (1) IE38031B1 (ja)
IL (1) IL42447A (ja)
LU (1) LU67781A1 (ja)
NL (1) NL7308349A (ja)
NO (1) NO138061C (ja)
PL (1) PL102580B1 (ja)
RO (1) RO62810A (ja)
SE (1) SE409855B (ja)
SU (1) SU578854A3 (ja)
YU (1) YU155673A (ja)
ZA (1) ZA734053B (ja)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4205176A (en) * 1978-10-18 1980-05-27 Cincinnati Milacron Chemicals Inc. Ester substituted oxazolines
US4247466A (en) * 1979-07-05 1981-01-27 American Cyanamid Company Lactone metabolites of 3-(4-biphenylylcarbonyl)propionic acid
JPS5735543A (en) * 1980-08-13 1982-02-26 Hisamitsu Pharmaceut Co Inc Novel phenylacetic acid derivative
JPS5762239A (en) * 1980-08-26 1982-04-15 Hisamitsu Pharmaceut Co Inc Novel phenylacetic acid derivative
DE3049405A1 (de) * 1980-12-23 1982-07-15 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue derivate von antiphlogistisch wirksamen carbonsaeuren, ihre herstellung und medizinische anwendung
US4792560A (en) * 1985-04-03 1988-12-20 Rorer Pharmaceutical Corporation Quinoline hydroxamates and their use as modulators of arachidonic acid metabolic pathways
US5071988A (en) * 1989-10-27 1991-12-10 American Home Products Corporation Substituted benzoylbenzene-, biphenyl- and 2-oxazole-alkanoic acid derivatives
US5218124A (en) * 1989-10-27 1993-06-08 American Home Products Corporation Substituted benzoylbenzene-, biphenyl- and 2-oxazole-alkanoic acid derivatives as inhibitors of pla2 and lipoxygenase
PH30449A (en) * 1991-11-25 1997-05-28 Lilly Co Eli Substituted phenyl phenol leukotriene antagonists
CN1100768C (zh) * 1994-10-06 2003-02-05 拜尔公司 取代的联苯基噁唑啉类化合物
FR2744445B1 (fr) * 1996-02-01 1998-10-02 Roussel Uclaf Composes biphenyles nouveaux et/ou a titre de medicament, compositions pharmaceutiques les contenant, leur procede de preparation et les intermediaires de ce procede
FR2880885B1 (fr) * 2005-01-14 2009-01-30 Merck Sante Soc Par Actions Si Derives d'acide phenylbenzoique, procedes pour leur preparation, compositions pharmaceutiques les contenant et applications en therapeutique
CA2643670A1 (en) * 2006-02-27 2007-08-30 Sterix Limited Diaryl compounds as non-steroidal inhibitors of 17-beta hydroxysteroid dehydrogenase and/or steroid sulphatase for the treatment of oestrogen-related diseases such as hormone dependent breast cancer

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1091403A (en) * 1964-01-24 1967-11-15 Boots Pure Drug Co Ltd Therapeutically active phenylalkane derivatives
US3624142A (en) * 1964-09-10 1971-11-30 Merck & Co Inc Substituted biphenyl acetic acid derivatives
US3671580A (en) * 1969-12-22 1972-06-20 Merck & Co Inc Substituted biphenyl acetic acids and ester derivatives thereof

Also Published As

Publication number Publication date
SU578854A3 (ru) 1977-10-30
FR2189036A1 (ja) 1974-01-25
FR2189036B1 (ja) 1980-04-11
IL42447A (en) 1977-05-31
FI57929C (fi) 1980-11-10
NO138061C (no) 1978-06-21
AU5700173A (en) 1974-12-19
ZA734053B (en) 1974-05-29
JPS4961144A (ja) 1974-06-13
CH584180A5 (ja) 1977-01-31
DD108977A5 (ja) 1974-10-12
HU167229B (ja) 1975-09-27
ATA522873A (de) 1975-07-15
PL102580B1 (pl) 1979-04-30
CA1012151A (en) 1977-06-14
YU155673A (en) 1981-04-30
LU67781A1 (ja) 1973-08-16
DE2329125A1 (de) 1974-01-03
RO62810A (fr) 1978-01-15
IE38031B1 (en) 1977-12-07
IE38031L (en) 1973-12-15
CS176239B2 (ja) 1977-06-30
US3969402A (en) 1976-07-13
FI57929B (fi) 1980-07-31
NO138061B (no) 1978-03-13
ES415919A1 (es) 1976-05-16
GB1396726A (en) 1975-06-04
AT329036B (de) 1976-04-26
NL7308349A (ja) 1973-12-18
BE800951A (fr) 1973-12-17
AR211760A1 (es) 1978-03-15
IL42447A0 (en) 1973-08-29

Similar Documents

Publication Publication Date Title
NO140731C (no) Fremgangsmaate for fremstilling av dimetyleter
SE395149B (sv) Forfarande for framstellning av dibenso-tiepinylpiperazinderivat
SE401676B (sv) Forfarande for framstellning av dibensofuranderivat
SE409855B (sv) Forfarande for framstellning av hydroxisubstituerade bifenylylpropionsyror och derivat derav
SE385698B (sv) Forfarande for framstellning av kinolinettiksyraderivat
SE382053B (sv) Forfarande for framstellning av bifenylylalkanoylaminopyridiner
SE383151B (sv) Forfarande for framstellning av 1-hydroxi-2-pyridoner
SE399425B (sv) Forfarande for framstellning av 1-fenoxi-3-aminopropan-2-ol-derivat
SE399708B (sv) Forfarande for framstellning av tioxanton-2-karboxylsyraderivat
SE404525B (sv) Forfarande for framstellning av 4-aminometyl-cyklohexan-karboxylsyra-1
SE396595B (sv) Forfarande for framstellning av difenylamin och derivat derav
SE380272B (sv) Forfarande for framstellning av n-fosfonmetylglycin
SE393111B (sv) Forfarande for framstellning av d-2-halogen-6-metyl-8-substituerad - ergolin
FI56830B (fi) Foerfarande foer framstaellning av asparaginylgrupper innehaollande biologiskt aktiva polypeptider
SE393808B (sv) Forfarande for framstellning av isomaltit
SE400086B (sv) Forfarande for framstellning av acylerade n(6)- aralkyl-adenosin-derivat
SE400287B (sv) Forfarande for framstellning av fluorsubstituerade tiaxantenderivat
SE391717B (sv) Forfarande for framstellning av 4-aryl-5-aminoalkyl-4-oxazolin-2-oner
SE404367B (sv) Forfarande for framstellning av derivat av homofolsyra
SE381456B (sv) Sett att framstella substituerade 5-cyklohexyl-indankarbonsyror och derivat av dessa
NO139086C (no) R fremgangsmaate for fremstilling av benzensulfonylurinstoffe
SE403112B (sv) Analogiforfarande for framstellning av skopolaminderivat
SE389862B (sv) Forfarande for framstellning av alfa-6-deoxitetracykliner
SE398352B (sv) Forfarande for framstellning av x-aminocyklopropylacetamidopenicillansyror och x-aminocyklobutylacetaamidopenicillansyror
SE373363B (sv) Forfarande for framstellning av kromon-2-karbonsyror och derivat derav