SE409469B - Forfarande for utforande av en enzymkatalyserad transformation av ett substrat - Google Patents
Forfarande for utforande av en enzymkatalyserad transformation av ett substratInfo
- Publication number
- SE409469B SE409469B SE7209058A SE905872A SE409469B SE 409469 B SE409469 B SE 409469B SE 7209058 A SE7209058 A SE 7209058A SE 905872 A SE905872 A SE 905872A SE 409469 B SE409469 B SE 409469B
- Authority
- SE
- Sweden
- Prior art keywords
- cells
- enzyme
- glucose
- substrate
- dried
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims description 31
- 108090000790 Enzymes Proteins 0.000 title claims description 24
- 102000004190 Enzymes Human genes 0.000 title claims description 24
- 239000000758 substrate Substances 0.000 title claims description 12
- 230000009466 transformation Effects 0.000 title claims description 11
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 24
- 238000000855 fermentation Methods 0.000 claims description 22
- 230000004151 fermentation Effects 0.000 claims description 22
- 239000008103 glucose Substances 0.000 claims description 22
- 239000007788 liquid Substances 0.000 claims description 20
- 229920000867 polyelectrolyte Polymers 0.000 claims description 16
- 229930091371 Fructose Natural products 0.000 claims description 10
- 239000005715 Fructose Substances 0.000 claims description 10
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 claims description 10
- 238000001035 drying Methods 0.000 claims description 8
- 125000002091 cationic group Chemical group 0.000 claims description 7
- 230000002255 enzymatic effect Effects 0.000 claims description 7
- 230000000813 microbial effect Effects 0.000 claims description 7
- 244000005700 microbiome Species 0.000 claims description 6
- 241000186063 Arthrobacter Species 0.000 claims description 5
- 125000000129 anionic group Chemical group 0.000 claims description 5
- 239000008394 flocculating agent Substances 0.000 claims description 5
- 241000187747 Streptomyces Species 0.000 claims description 3
- 229920001448 anionic polyelectrolyte Polymers 0.000 claims description 2
- 230000003311 flocculating effect Effects 0.000 claims 1
- 239000000243 solution Substances 0.000 description 34
- 239000000463 material Substances 0.000 description 20
- 230000000694 effects Effects 0.000 description 12
- 238000005189 flocculation Methods 0.000 description 10
- 230000016615 flocculation Effects 0.000 description 10
- 239000002609 medium Substances 0.000 description 9
- 238000003756 stirring Methods 0.000 description 7
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 6
- 238000006243 chemical reaction Methods 0.000 description 6
- 238000006317 isomerization reaction Methods 0.000 description 6
- 238000011282 treatment Methods 0.000 description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 6
- 238000004220 aggregation Methods 0.000 description 5
- 230000002776 aggregation Effects 0.000 description 5
- 238000013019 agitation Methods 0.000 description 5
- 235000015097 nutrients Nutrition 0.000 description 5
- 239000002245 particle Substances 0.000 description 5
- 238000003828 vacuum filtration Methods 0.000 description 5
- 229940041514 candida albicans extract Drugs 0.000 description 4
- 241000894007 species Species 0.000 description 4
- 238000000844 transformation Methods 0.000 description 4
- 239000012138 yeast extract Substances 0.000 description 4
- 102000004195 Isomerases Human genes 0.000 description 3
- 108090000769 Isomerases Proteins 0.000 description 3
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 3
- 239000001888 Peptone Substances 0.000 description 3
- 108010080698 Peptones Proteins 0.000 description 3
- 239000003463 adsorbent Substances 0.000 description 3
- 230000001413 cellular effect Effects 0.000 description 3
- 238000001914 filtration Methods 0.000 description 3
- 230000008014 freezing Effects 0.000 description 3
- 238000007710 freezing Methods 0.000 description 3
- 239000008101 lactose Substances 0.000 description 3
- 235000019319 peptone Nutrition 0.000 description 3
- 230000000737 periodic effect Effects 0.000 description 3
- 229920002401 polyacrylamide Polymers 0.000 description 3
- 238000000746 purification Methods 0.000 description 3
- 239000002002 slurry Substances 0.000 description 3
- 239000000725 suspension Substances 0.000 description 3
- 241000228245 Aspergillus niger Species 0.000 description 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- RGHNJXZEOKUKBD-SQOUGZDYSA-N D-gluconic acid Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O RGHNJXZEOKUKBD-SQOUGZDYSA-N 0.000 description 2
- SRBFZHDQGSBBOR-IOVATXLUSA-N D-xylopyranose Chemical compound O[C@@H]1COC(O)[C@H](O)[C@H]1O SRBFZHDQGSBBOR-IOVATXLUSA-N 0.000 description 2
- 108010093096 Immobilized Enzymes Proteins 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 241000218589 Streptomyces olivaceus Species 0.000 description 2
- 229930006000 Sucrose Natural products 0.000 description 2
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 2
- 150000001720 carbohydrates Chemical class 0.000 description 2
- 235000014633 carbohydrates Nutrition 0.000 description 2
- 239000012876 carrier material Substances 0.000 description 2
- 238000005119 centrifugation Methods 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 238000010924 continuous production Methods 0.000 description 2
- 239000008121 dextrose Substances 0.000 description 2
- 239000007789 gas Substances 0.000 description 2
- 239000011521 glass Substances 0.000 description 2
- 238000000227 grinding Methods 0.000 description 2
- 239000002054 inoculum Substances 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 238000006722 reduction reaction Methods 0.000 description 2
- 238000004062 sedimentation Methods 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- 238000012289 standard assay Methods 0.000 description 2
- 238000003860 storage Methods 0.000 description 2
- 239000005720 sucrose Substances 0.000 description 2
- 239000006188 syrup Substances 0.000 description 2
- 235000020357 syrup Nutrition 0.000 description 2
- PJVXUVWGSCCGHT-ZPYZYFCMSA-N (2r,3s,4r,5r)-2,3,4,5,6-pentahydroxyhexanal;(3s,4r,5r)-1,3,4,5,6-pentahydroxyhexan-2-one Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O.OC[C@@H](O)[C@@H](O)[C@H](O)C(=O)CO PJVXUVWGSCCGHT-ZPYZYFCMSA-N 0.000 description 1
- 240000006439 Aspergillus oryzae Species 0.000 description 1
- 235000002247 Aspergillus oryzae Nutrition 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 101100283604 Caenorhabditis elegans pigk-1 gene Proteins 0.000 description 1
- RGHNJXZEOKUKBD-UHFFFAOYSA-N D-gluconic acid Natural products OCC(O)C(O)C(O)C(O)C(O)=O RGHNJXZEOKUKBD-UHFFFAOYSA-N 0.000 description 1
- 229920002307 Dextran Polymers 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 239000005909 Kieselgur Substances 0.000 description 1
- FFEARJCKVFRZRR-UHFFFAOYSA-N L-Methionine Natural products CSCCC(N)C(O)=O FFEARJCKVFRZRR-UHFFFAOYSA-N 0.000 description 1
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 description 1
- 229930195722 L-methionine Natural products 0.000 description 1
- 241000556720 Manga Species 0.000 description 1
- 108010070551 Meat Proteins Proteins 0.000 description 1
- XUYPXLNMDZIRQH-UHFFFAOYSA-N N-acetylmethionine Chemical compound CSCCC(C(O)=O)NC(C)=O XUYPXLNMDZIRQH-UHFFFAOYSA-N 0.000 description 1
- 239000004952 Polyamide Substances 0.000 description 1
- 229920002873 Polyethylenimine Polymers 0.000 description 1
- 108010039918 Polylysine Proteins 0.000 description 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 1
- 235000014680 Saccharomyces cerevisiae Nutrition 0.000 description 1
- 241000133261 Scabropezia flavovirens Species 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- 241000187759 Streptomyces albus Species 0.000 description 1
- 239000008351 acetate buffer Substances 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 239000003513 alkali Substances 0.000 description 1
- WQZGKKKJIJFFOK-PHYPRBDBSA-N alpha-D-galactose Chemical compound OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@H]1O WQZGKKKJIJFFOK-PHYPRBDBSA-N 0.000 description 1
- 229940037003 alum Drugs 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- PYMYPHUHKUWMLA-UHFFFAOYSA-N arabinose Natural products OCC(O)C(O)C(O)C=O PYMYPHUHKUWMLA-UHFFFAOYSA-N 0.000 description 1
- 239000010425 asbestos Substances 0.000 description 1
- 230000000712 assembly Effects 0.000 description 1
- 238000000429 assembly Methods 0.000 description 1
- 239000011324 bead Substances 0.000 description 1
- SRBFZHDQGSBBOR-UHFFFAOYSA-N beta-D-Pyranose-Lyxose Natural products OC1COC(O)C(O)C1O SRBFZHDQGSBBOR-UHFFFAOYSA-N 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 239000010796 biological waste Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000006172 buffering agent Substances 0.000 description 1
- 239000004202 carbamide Substances 0.000 description 1
- 150000001768 cations Chemical class 0.000 description 1
- 239000006285 cell suspension Substances 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- RCTYPNKXASFOBE-UHFFFAOYSA-M chloromercury Chemical compound [Hg]Cl RCTYPNKXASFOBE-UHFFFAOYSA-M 0.000 description 1
- 238000005352 clarification Methods 0.000 description 1
- 239000000356 contaminant Substances 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 238000010908 decantation Methods 0.000 description 1
- 230000018044 dehydration Effects 0.000 description 1
- 238000006297 dehydration reaction Methods 0.000 description 1
- 238000006356 dehydrogenation reaction Methods 0.000 description 1
- 238000004925 denaturation Methods 0.000 description 1
- 230000036425 denaturation Effects 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 230000008021 deposition Effects 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 239000000839 emulsion Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 239000010419 fine particle Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 229930182830 galactose Natural products 0.000 description 1
- 239000000174 gluconic acid Substances 0.000 description 1
- 235000012208 gluconic acid Nutrition 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 235000019534 high fructose corn syrup Nutrition 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- 230000003100 immobilizing effect Effects 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 239000002198 insoluble material Substances 0.000 description 1
- 230000003834 intracellular effect Effects 0.000 description 1
- 229960004903 invert sugar Drugs 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 229960004452 methionine Drugs 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 235000013379 molasses Nutrition 0.000 description 1
- 230000017066 negative regulation of growth Effects 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 229920001467 poly(styrenesulfonates) Polymers 0.000 description 1
- 229920002647 polyamide Polymers 0.000 description 1
- 229920000768 polyamine Polymers 0.000 description 1
- 229920000656 polylysine Polymers 0.000 description 1
- 239000011970 polystyrene sulfonate Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 229910052895 riebeckite Inorganic materials 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 238000007873 sieving Methods 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/02—Separating microorganisms from their culture media
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/24—Preparation of compounds containing saccharide radicals produced by the action of an isomerase, e.g. fructose
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/813—Continuous fermentation
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/83—Arthrobacter
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/886—Streptomyces
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/886—Streptomyces
- Y10S435/902—Streptomyces olivaceus
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/911—Microorganisms using fungi
- Y10S435/913—Aspergillus
- Y10S435/917—Aspergillus niger
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/911—Microorganisms using fungi
- Y10S435/913—Aspergillus
- Y10S435/918—Aspergillus oryzae
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/911—Microorganisms using fungi
- Y10S435/94—Saccharomyces
- Y10S435/942—Saccharomyces cerevisiae
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Fertilizers (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US00161337A US3821086A (en) | 1971-07-09 | 1971-07-09 | Enzymatic process using immobilized microbial cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE409469B true SE409469B (sv) | 1979-08-20 |
Family
ID=22580787
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7209058A SE409469B (sv) | 1971-07-09 | 1972-07-07 | Forfarande for utforande av en enzymkatalyserad transformation av ett substrat |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US3821086A (OSRAM) |
| JP (2) | JPS547873B1 (OSRAM) |
| AT (1) | AT314452B (OSRAM) |
| BE (1) | BE785810A (OSRAM) |
| CA (2) | CA978118A (OSRAM) |
| CH (1) | CH554941A (OSRAM) |
| DE (1) | DE2232645C3 (OSRAM) |
| DK (1) | DK136073B (OSRAM) |
| ES (1) | ES404521A1 (OSRAM) |
| FI (1) | FI49319C (OSRAM) |
| FR (1) | FR2145486B1 (OSRAM) |
| GB (1) | GB1368650A (OSRAM) |
| IL (1) | IL39809A (OSRAM) |
| IT (1) | IT988061B (OSRAM) |
| NL (1) | NL158846B (OSRAM) |
| NO (1) | NO140233C (OSRAM) |
| SE (1) | SE409469B (OSRAM) |
| ZA (1) | ZA724544B (OSRAM) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS531832B2 (OSRAM) * | 1972-07-03 | 1978-01-23 | ||
| US3989597A (en) * | 1974-03-28 | 1976-11-02 | R. J. Reynolds Tobacco Company | Aggregate of flocculated cells |
| US3989596A (en) * | 1974-03-28 | 1976-11-02 | R. J. Reynolds Tobacco Company | Aggregate of dried flocculated cells |
| GB1451273A (en) * | 1974-03-29 | 1976-09-29 | Ici Ltd | Glucose isomerase |
| US3939041A (en) * | 1974-05-31 | 1976-02-17 | Corning Glass Works | Method of making fructose |
| US3980521A (en) * | 1974-08-28 | 1976-09-14 | Novo Industri A/S | Immobilization of glucose isomerase |
| US3935069A (en) * | 1974-12-23 | 1976-01-27 | R. J. Reynolds Tobacco Company | Enzymatic process using immobilized microbial cells |
| US4025389A (en) * | 1975-03-13 | 1977-05-24 | Novo Industri A/S | Process and isomerizing glucose |
| JPS5244285A (en) * | 1975-10-02 | 1977-04-07 | Norin Suisansyo Shokuhin Sogo Kenkyusho | Method of treating microbial cells containing glucose isomerase |
| US4138290A (en) * | 1976-04-22 | 1979-02-06 | Novo Laboratories, Incorporated | Glucose isomerization under expanded bed conditions |
| US4173514A (en) * | 1977-06-02 | 1979-11-06 | Ici Americas Inc. | High mannitol process (enzymatic isomerization) |
| US4212943A (en) * | 1978-03-27 | 1980-07-15 | Miles Laboratories, Inc. | Production of bacterial cell aggregate |
| DK146942C (da) * | 1978-04-19 | 1984-07-30 | Novo Industri As | Fremgangsmaade til fremstilling af et immobiliseret enzymprodukt |
| DE3165230D1 (en) * | 1980-08-22 | 1984-09-06 | Wallone Region | Process for the immobilisation of globular microbial cells by means of adhesion to a solid support |
| DE3165062D1 (en) * | 1980-08-22 | 1984-08-30 | Wallone Region | Process for the immobilisation of globular microbial cells by means of adhesion to a solid support |
| CN102018280B (zh) * | 2009-09-10 | 2012-12-05 | 湖北中烟工业有限责任公司 | 烟草薄片原料萃取液除杂专用吸附澄清剂的生产方法 |
| CN102018279B (zh) * | 2009-09-10 | 2013-01-23 | 湖北中烟工业有限责任公司 | 烟草薄片原料萃取液的综合除杂新工艺及除杂系统 |
| CN110678542A (zh) | 2017-05-30 | 2020-01-10 | 花王株式会社 | 丝状菌颗粒的制造方法 |
| USD870826S1 (en) * | 2018-03-30 | 2019-12-24 | Xu Jiajia | Toy |
-
0
- BE BE785810D patent/BE785810A/xx not_active IP Right Cessation
-
1971
- 1971-07-09 US US00161337A patent/US3821086A/en not_active Expired - Lifetime
-
1972
- 1972-07-03 FI FI721886A patent/FI49319C/fi active
- 1972-07-03 IL IL39809A patent/IL39809A/xx unknown
- 1972-07-03 CH CH992872A patent/CH554941A/fr not_active IP Right Cessation
- 1972-07-03 ZA ZA724544A patent/ZA724544B/xx unknown
- 1972-07-03 FR FR7223985A patent/FR2145486B1/fr not_active Expired
- 1972-07-03 DE DE2232645A patent/DE2232645C3/de not_active Expired
- 1972-07-04 CA CA146,266A patent/CA978118A/en not_active Expired
- 1972-07-04 GB GB3118472A patent/GB1368650A/en not_active Expired
- 1972-07-04 ES ES404521A patent/ES404521A1/es not_active Expired
- 1972-07-05 AT AT577372A patent/AT314452B/de not_active IP Right Cessation
- 1972-07-07 JP JP6810872A patent/JPS547873B1/ja active Pending
- 1972-07-07 NL NL7209532.A patent/NL158846B/xx not_active IP Right Cessation
- 1972-07-07 SE SE7209058A patent/SE409469B/sv unknown
- 1972-07-07 DK DK339972AA patent/DK136073B/da not_active IP Right Cessation
- 1972-07-07 NO NO2438/72A patent/NO140233C/no unknown
- 1972-07-08 IT IT51430/72A patent/IT988061B/it active
-
1977
- 1977-03-07 CA CA273,308A patent/CA1030087B/en not_active Expired
- 1977-09-16 JP JP11059277A patent/JPS5344682A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| FR2145486B1 (OSRAM) | 1974-12-27 |
| ZA724544B (en) | 1973-03-28 |
| CH554941A (fr) | 1974-10-15 |
| FI49319C (fi) | 1975-05-12 |
| GB1368650A (en) | 1974-10-02 |
| BE785810A (fr) | 1973-01-04 |
| DE2232645A1 (de) | 1973-02-01 |
| DE2232645C3 (de) | 1979-03-29 |
| AU4420672A (en) | 1973-08-02 |
| JPS5344682A (en) | 1978-04-21 |
| NL7209532A (OSRAM) | 1973-01-11 |
| US3821086A (en) | 1974-06-28 |
| FI49319B (OSRAM) | 1975-01-31 |
| FR2145486A1 (OSRAM) | 1973-02-23 |
| NL158846B (nl) | 1978-12-15 |
| JPS547873B1 (OSRAM) | 1979-04-10 |
| DK136073B (da) | 1977-08-08 |
| CA978118A (en) | 1975-11-18 |
| CA1030087B (en) | 1978-04-25 |
| IT988061B (it) | 1975-04-10 |
| IL39809A0 (en) | 1972-09-28 |
| DE2232645B2 (de) | 1978-07-20 |
| AT314452B (de) | 1974-04-10 |
| NO140233B (no) | 1979-04-17 |
| IL39809A (en) | 1975-06-25 |
| DK136073C (OSRAM) | 1978-01-09 |
| JPS578716B2 (OSRAM) | 1982-02-17 |
| NO140233C (no) | 1979-07-25 |
| ES404521A1 (es) | 1975-11-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SE409469B (sv) | Forfarande for utforande av en enzymkatalyserad transformation av ett substrat | |
| CA1259939A (en) | Production of isomaltulose | |
| US4355105A (en) | Glutaraldehyde/polyethylenimine immobilization of whole microbial cells | |
| CN103266152B (zh) | 一种利用固定化海藻糖合成酶生产海藻糖的方法 | |
| Ramesh et al. | Ability of a solid state fermentation technique to significantly minimize catabolic repression of α-amylase production by Bacillus licheniformis M27 | |
| CA1050454A (en) | Shaped product containing glucose isomerase and method of producing said product | |
| EP2252699A2 (en) | Production of high purity galactooligosaccharides | |
| TW201307565A (zh) | 由樹汁製造異麥芽酮糖的方法 | |
| IL35734A (en) | The preparation of an immobilized glucose isomerase enzyme composition | |
| Park et al. | Effect of dissolved oxygen concentration and impeller tip speed on itaconic acid production by Aspergillus terreus | |
| JP2020505956A (ja) | イソマルツロース結晶とトレハルロースとを含む固体材料の製造方法 | |
| CN113817635A (zh) | 一种利用大豆乳清废水培养芽孢杆菌的方法 | |
| Brady et al. | Ethanol production at 45 C by alginate-immobilized Kluyveromyces marxianus IMB3 during growth on lactose-containing media | |
| US3989597A (en) | Aggregate of flocculated cells | |
| US3989596A (en) | Aggregate of dried flocculated cells | |
| USRE29130E (en) | Enzymatic process using immobilized microbial cells | |
| CN113249372A (zh) | 一种用于甘露糖生产的固定化细胞的制备方法及其应用 | |
| DK153410B (da) | Fremgangsmaade til fremstilling af et alfa-galactosidase-enzympraeparat og fremgangsmaade til hydrolyse af raffinose under anvendelse af dette enzympraeparat | |
| Afschar et al. | Continuous production of acetone and butanol with shear-activated Clostridium acetobutylicum | |
| Su et al. | Enzymatic saccharification of cellulose by thermophilic actinomyces | |
| HÄggström et al. | Continuous production of butanol with immobilized cells of Clostridium acetobutylicum | |
| US20240209404A1 (en) | Preparation method for and application of immobilized cell for tagatose production | |
| RU2253677C2 (ru) | Иммобилизованный биокатализатор, способ его получения и способ получения молочной кислоты с использованием этого биокатализатора | |
| USRE29136E (en) | Enzymatic process using immobilized microbial cells | |
| Jang et al. | Improvement of oxidoreductase stability of cethyltrimethylammoniumbromide permeabilized cells of Zymomonas mobilis through glutaraldehyde crosslinking |