SE397525B - Sett att framstella nya 1-ocyl-3-indolinetanoler att anvendas som mellanprodukter for framstellning av 3-(2-(4-fenyl-1-piperazinyl)-etyl)-indoliner - Google Patents

Sett att framstella nya 1-ocyl-3-indolinetanoler att anvendas som mellanprodukter for framstellning av 3-(2-(4-fenyl-1-piperazinyl)-etyl)-indoliner

Info

Publication number
SE397525B
SE397525B SE7402375A SE237574A SE397525B SE 397525 B SE397525 B SE 397525B SE 7402375 A SE7402375 A SE 7402375A SE 237574 A SE237574 A SE 237574A SE 397525 B SE397525 B SE 397525B
Authority
SE
Sweden
Prior art keywords
indolinetanols
ocyl
indolines
piperazinyl
intermediates
Prior art date
Application number
SE7402375A
Other languages
English (en)
Swedish (sv)
Inventor
Jr G R Allen
F J Mcevoy
V G Devries
D B Moran
R Littell
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of SE397525B publication Critical patent/SE397525B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/26Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32Oxygen atoms
    • C07D209/34Oxygen atoms in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/66Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE7402375A 1971-05-27 1972-05-26 Sett att framstella nya 1-ocyl-3-indolinetanoler att anvendas som mellanprodukter for framstellning av 3-(2-(4-fenyl-1-piperazinyl)-etyl)-indoliner SE397525B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14770071A 1971-05-27 1971-05-27

Publications (1)

Publication Number Publication Date
SE397525B true SE397525B (sv) 1977-11-07

Family

ID=22522572

Family Applications (4)

Application Number Title Priority Date Filing Date
SE7402374A SE397524B (sv) 1971-05-27 1972-05-26 Indolinderivat avsedda att anvendas som mellanprodukter for framstellning av 3-(2-(4-fenyl-1-piperazinyl)-etyl)-indoliner med terapeutisk verkan
SE7402375A SE397525B (sv) 1971-05-27 1972-05-26 Sett att framstella nya 1-ocyl-3-indolinetanoler att anvendas som mellanprodukter for framstellning av 3-(2-(4-fenyl-1-piperazinyl)-etyl)-indoliner
SE7206918A SE395455B (sv) 1971-05-27 1972-05-26 Forfarande for framstellning av 3-(fenyl-piperazinyl) etylindoliner
SE7600531A SE7600531L (sv) 1971-05-27 1976-01-20 Forfarande for framstellning av 3-(2-(4-fenyl-1-piperazinyl)-etyl)-indoliner

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SE7402374A SE397524B (sv) 1971-05-27 1972-05-26 Indolinderivat avsedda att anvendas som mellanprodukter for framstellning av 3-(2-(4-fenyl-1-piperazinyl)-etyl)-indoliner med terapeutisk verkan

Family Applications After (2)

Application Number Title Priority Date Filing Date
SE7206918A SE395455B (sv) 1971-05-27 1972-05-26 Forfarande for framstellning av 3-(fenyl-piperazinyl) etylindoliner
SE7600531A SE7600531L (sv) 1971-05-27 1976-01-20 Forfarande for framstellning av 3-(2-(4-fenyl-1-piperazinyl)-etyl)-indoliner

Country Status (20)

Country Link
US (1) US3751416A (ro)
AR (4) AR194595A1 (ro)
BE (1) BE784012A (ro)
BG (5) BG19151A3 (ro)
CA (1) CA1014154A (ro)
CH (5) CH582142A5 (ro)
CS (3) CS185203B2 (ro)
DD (1) DD100471A5 (ro)
DE (1) DE2225765A1 (ro)
ES (4) ES403245A1 (ro)
FR (1) FR2139158B1 (ro)
GB (2) GB1382916A (ro)
HU (3) HU168720B (ro)
NL (1) NL7207129A (ro)
NO (1) NO136795C (ro)
PL (4) PL92634B1 (ro)
RO (4) RO63715A (ro)
SE (4) SE397524B (ro)
SU (4) SU489321A3 (ro)
ZA (1) ZA722916B (ro)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3888861A (en) * 1974-01-07 1975-06-10 Colgate Palmolive Co 3-(2-(4-substituted-piperazin-1-yl)ethyl)indoles
US4089853A (en) * 1977-02-09 1978-05-16 American Cyanamid Company Process for the preparation of cis-5,6-dimethoxy-2-methyl-3-[2-(4-phenyl-1-piperazinyl)-ethyl]indoline
FR2421900A1 (fr) * 1977-03-17 1979-11-02 Sauba Lab Piperazino-3-indoles, leur procede de preparation et leurs applications therapeutiques
GR65270B (en) 1978-10-10 1980-07-31 Fujisawa Pharmaceutical Co Isatin derivatives and processes for the preparation thereof
US4224330A (en) * 1979-09-13 1980-09-23 Zoecon Corporation Esters and thiolesters of benzothienyl acids
US4411900A (en) * 1980-01-03 1983-10-25 Fujisawa Pharmaceutical Co., Ltd. Benzhydrylpiperozinyl thiazole derivatives and pharmaceutical composition comprising the same
US4302589A (en) * 1980-05-08 1981-11-24 American Cyanamid Company Cis-mono and disubstituted-2-methyl-3-[(piperazinyl) and (piperidino)ethyl]indolines, intermediates for their preparation and methods of preparation
CA1248531A (en) * 1984-04-17 1989-01-10 Jeffrey C. Watkins 4-substituted piperazine-2-carboxylic acids
JPH05255089A (ja) * 1991-12-18 1993-10-05 Sanwa Kagaku Kenkyusho Co Ltd 抗ウイルス剤

Also Published As

Publication number Publication date
US3751416A (en) 1973-08-07
BG19593A3 (ro) 1975-06-25
SE7600531L (sv) 1976-01-20
ZA722916B (en) 1973-02-28
BG20791A3 (ro) 1975-12-20
NO136795B (no) 1977-08-01
ES409282A1 (es) 1976-03-16
ES409281A1 (es) 1976-03-16
ES403245A1 (es) 1975-04-16
CS185203B2 (en) 1978-09-15
CH583701A5 (ro) 1977-01-14
HU168720B (ro) 1976-07-28
SU489321A3 (ru) 1975-10-25
RO60145A (ro) 1976-09-15
CA1014154A (en) 1977-07-19
BE784012A (fr) 1972-11-27
RO64489A (fr) 1979-05-15
RO63715A (fr) 1978-10-15
CS185244B2 (en) 1978-09-15
SE397524B (sv) 1977-11-07
HU167203B (ro) 1975-09-27
BG18866A3 (ro) 1975-03-20
BG19594A3 (ro) 1975-06-25
SU575024A3 (ru) 1977-09-30
DD100471A5 (ro) 1973-09-20
FR2139158A1 (ro) 1973-01-05
ES409284A1 (es) 1976-03-16
PL81987B1 (ro) 1975-10-31
RO63730A (fr) 1978-11-15
SU488408A3 (ru) 1975-10-15
AR194595A1 (es) 1973-07-31
HU166178B (ro) 1975-02-28
SU489322A3 (ru) 1975-10-25
SE395455B (sv) 1977-08-15
CH582172A5 (ro) 1976-11-30
AR208646A1 (es) 1977-02-28
FR2139158B1 (ro) 1975-10-17
PL92634B1 (ro) 1977-04-30
CH579563A5 (ro) 1976-09-15
GB1382917A (en) 1975-02-05
PL92635B1 (ro) 1977-04-30
CH582142A5 (ro) 1976-11-30
PL92627B1 (ro) 1977-04-30
AU4191872A (en) 1973-11-08
CS185245B2 (en) 1978-09-15
AR208647A1 (es) 1977-02-28
NL7207129A (ro) 1972-11-29
AR210562A1 (es) 1977-08-31
DE2225765A1 (de) 1972-12-07
BG19151A3 (ro) 1975-04-30
GB1382916A (en) 1975-02-05
CH583700A5 (ro) 1977-01-14
NO136795C (no) 1977-11-09

Similar Documents

Publication Publication Date Title
SE423631B (sv) Forfarande for framstellning av oxaalhyl-dialkylxantiner
SE374375B (sv) Analogiforfarande for framstellning av nya 4-(3-karboxi-4-hydroxi-fenylazo)-bensensulfonamido-pyridiner
SE7710599L (sv) Forfarande for framstellning av bensisoxazoler
SE385118B (sv) Forfarande for framstellning av 2-(6-metoxi-2-naftyl)-propionsyra
SE424994B (sv) Forfarande for framstellning av nya pseudotrisackarider
SE416731B (sv) Forfarande for framstellning av nya penicilliner
SE411212B (sv) Forfarande for framstellning av 3-halogen-cefalosporiner
SE397525B (sv) Sett att framstella nya 1-ocyl-3-indolinetanoler att anvendas som mellanprodukter for framstellning av 3-(2-(4-fenyl-1-piperazinyl)-etyl)-indoliner
NO146203C (no) Fremgangsmaate til fremstilling av cephalexin eller salter derav
NO146596C (no) Fremgangsmaate for fremstilling av 6-deoksytetracykliner
SE397680B (sv) Forfarande for framstellning av nya heterocykliska estrar av bensopyranopyridiner
NO790627L (no) Fremgangsmaate for fremstilling av hydroksyalkylxantiner
SE417601B (sv) Forfarande for framstellning av amidinokarbamider
SE418085B (sv) Forfarande for framstellning av nya sulfamoylbensoesyraamider
SE7608956L (sv) Forfarande for framstellning av 2-(fenoxialkyltio)-5-nitroimidazoler
NO843825L (no) Fremgangsmaate for fremstilling av 6-deoksytetracyklin
SE417319B (sv) Analogiforfarande for framstellning av ergopeptiner
SE399417B (sv) Forfarande for framstellning av 4-(4-bifenylyl)-1-butanol
SE412756B (sv) Alternativa forfarande for framstellning av 2-(aminofenylimino)-3-aza-1-tia-cykloalkaner
SE404801B (sv) Forfaranden for framstellning av nya tiazolderivat
SE411211B (sv) Forfarande for framstellning av 3-halogencefalosporiner
SE409994B (sv) Forfarande for framstellning av amidinokarbamider
SE386681B (sv) Forfarande for framstellning av nya cefalosporinderivat
SE384210B (sv) Forfarande for framstellning av nya nitrosokarbamidderivat
SE415975B (sv) Forfarande for framstellning av nya bensylpyrimidiner