SE393374B - Forfarande for framstellning av 2-alkyl-2-dialkylamino-2, '6'-acetoxylidider med lokalestetisk effekt - Google Patents

Forfarande for framstellning av 2-alkyl-2-dialkylamino-2, '6'-acetoxylidider med lokalestetisk effekt

Info

Publication number
SE393374B
SE393374B SE7115656A SE1565671A SE393374B SE 393374 B SE393374 B SE 393374B SE 7115656 A SE7115656 A SE 7115656A SE 1565671 A SE1565671 A SE 1565671A SE 393374 B SE393374 B SE 393374B
Authority
SE
Sweden
Prior art keywords
acetoxylidides
dialkylamino
alkyl
procedure
preparation
Prior art date
Application number
SE7115656A
Other languages
English (en)
Swedish (sv)
Inventor
H J F Adams
G H Kronberg
B H Takman
Original Assignee
Astra Pharma Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Pharma Prod filed Critical Astra Pharma Prod
Publication of SE393374B publication Critical patent/SE393374B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C53/00Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
    • C07C53/38Acyl halides
    • C07C53/46Acyl halides containing halogen outside the carbonyl halide group
    • C07C53/50Acyl halides containing halogen outside the carbonyl halide group of acids containing three or more carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SE7115656A 1970-12-22 1971-12-07 Forfarande for framstellning av 2-alkyl-2-dialkylamino-2, '6'-acetoxylidider med lokalestetisk effekt SE393374B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10077770A 1970-12-22 1970-12-22
US00164022A US3812147A (en) 1970-12-22 1971-07-19 Acylxylidide local anaesthetics

Publications (1)

Publication Number Publication Date
SE393374B true SE393374B (sv) 1977-05-09

Family

ID=26797539

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7115656A SE393374B (sv) 1970-12-22 1971-12-07 Forfarande for framstellning av 2-alkyl-2-dialkylamino-2, '6'-acetoxylidider med lokalestetisk effekt

Country Status (23)

Country Link
US (1) US3812147A (cs)
JP (1) JPS5644063B1 (cs)
AR (1) AR193840A1 (cs)
AT (1) AT319205B (cs)
AU (1) AU468489B2 (cs)
BE (1) BE776656A (cs)
BR (1) BR7108466D0 (cs)
CA (1) CA943966A (cs)
DD (1) DD99779A5 (cs)
DE (1) DE2162744C3 (cs)
DK (1) DK139814B (cs)
ES (2) ES398210A1 (cs)
FI (1) FI55027C (cs)
FR (1) FR2118985B1 (cs)
GB (1) GB1369259A (cs)
HU (1) HU163373B (cs)
IE (1) IE35909B1 (cs)
IT (1) IT1066334B (cs)
NL (2) NL172149C (cs)
NO (1) NO135934C (cs)
PL (1) PL83097B1 (cs)
SE (1) SE393374B (cs)
SU (1) SU419023A3 (cs)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4237068A (en) * 1971-07-28 1980-12-02 Astra Pharmaceutical Products, Inc. Primary aminoacylanilides
US3966934A (en) * 1971-12-08 1976-06-29 Astra Pharmaceutical Products, Inc. Synergistic local anesthetic compositions
US3957996A (en) * 1971-12-08 1976-05-18 Astra Pharmaceutical Products, Inc. Pharmaceutical local anesthetic compositions
US3975443A (en) * 1972-06-06 1976-08-17 Allen & Hanburys Limited 1-(3,4-dichlorobenzamidomethyl)-cyclohexyldimethylamine
JPS598269B2 (ja) * 1975-08-22 1984-02-23 萬有製薬株式会社 オメガ − アミノアルカンサンアリ−ルアミドノ セイホウ
EP0062322A1 (en) * 1981-04-03 1982-10-13 The B.F. GOODRICH Company Improved process for synthesis of hindered amine stabilizers for polymeric materials
US4891058A (en) * 1988-07-18 1990-01-02 Ici Americas Inc. 1-alkyl-3-aryl imidazolidine-2,4-diones and herbicidal use
SE8900685D0 (sv) * 1989-02-28 1989-02-28 Astra Ab New compounds
US5153226A (en) * 1989-08-31 1992-10-06 Warner-Lambert Company Acat inhibitors for treating hypocholesterolemia
KR20140097446A (ko) 2006-11-20 2014-08-06 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 통증 및 소양증 치료용 방법, 조성물 및 키트
CA3027255C (en) 2009-07-10 2022-06-21 The General Hospital Corporation Permanently charged sodium and calcium channel blockers as anti-inflammatory agents
CN108348774A (zh) 2015-08-03 2018-07-31 哈佛大学校长及研究员协会 带电离子通道阻断剂及其应用
MX2021010869A (es) 2019-03-11 2022-01-19 Nocion Therapeutics Inc Bloqueadores de canales iónicos sustituidos por éster y métodos para su uso.
US10780083B1 (en) 2019-03-11 2020-09-22 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
US10828287B2 (en) 2019-03-11 2020-11-10 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
EP3938345A4 (en) 2019-03-11 2023-01-18 Nocion Therapeutics, Inc. CHARGED ION CHANNEL BLOCKERS AND METHODS OF USE
KR20210143791A (ko) 2019-03-11 2021-11-29 녹시온 테라퓨틱스 인코포레이티드 하전된 이온 채널 차단제 및 사용 방법
EP4054586A4 (en) 2019-11-06 2023-11-22 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
CN114828845A (zh) 2019-11-06 2022-07-29 诺西恩医疗公司 带电的离子通道阻滞剂及其使用方法
IL295950A (en) 2020-03-11 2022-10-01 Nocion Therapeutics Inc Charged ion channel blockers and methods of use
US12162851B2 (en) 2020-03-11 2024-12-10 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1124837A (en) * 1966-06-03 1968-08-21 Wyeth John & Brother Ltd Substituted anilides

Also Published As

Publication number Publication date
IE35909L (en) 1972-06-22
AU468489B2 (en) 1976-01-15
NL172149C (nl) 1983-07-18
ES425626A1 (es) 1976-06-16
FR2118985A1 (cs) 1972-08-04
NL8204126A (nl) 1983-02-01
ES398210A1 (es) 1975-03-16
PL83097B1 (cs) 1975-12-31
NL172149B (nl) 1983-02-16
DK139814C (cs) 1979-10-01
NO135934B (cs) 1977-03-21
JPS5644063B1 (cs) 1981-10-16
BE776656A (fr) 1972-06-14
IE35909B1 (en) 1976-06-23
FR2118985B1 (cs) 1975-12-26
DD99779A5 (cs) 1973-08-20
NO135934C (cs) 1977-06-29
AU3709971A (en) 1973-06-28
DK139814B (da) 1979-04-23
FI55027C (fi) 1979-05-10
SU419023A3 (ru) 1974-03-05
AT319205B (de) 1974-12-10
FI55027B (fi) 1979-01-31
AR193840A1 (es) 1973-05-31
GB1369259A (en) 1974-10-23
BR7108466D0 (pt) 1973-06-14
CA943966A (en) 1974-03-19
NL7117644A (cs) 1972-06-26
DE2162744B2 (de) 1981-07-02
DE2162744A1 (de) 1972-07-06
DE2162744C3 (de) 1982-04-15
HU163373B (cs) 1973-08-28
IT1066334B (it) 1985-03-04
US3812147A (en) 1974-05-21

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