SE391718B - Ny optiskt aktiv lakton till anvendning vid syntes av (+)-biotin jemte forfarande for framstellning av laktonen - Google Patents

Ny optiskt aktiv lakton till anvendning vid syntes av (+)-biotin jemte forfarande for framstellning av laktonen

Info

Publication number
SE391718B
SE391718B SE1613270A SE1613270A SE391718B SE 391718 B SE391718 B SE 391718B SE 1613270 A SE1613270 A SE 1613270A SE 1613270 A SE1613270 A SE 1613270A SE 391718 B SE391718 B SE 391718B
Authority
SE
Sweden
Prior art keywords
lacton
biotine
synthesis
accordance
production
Prior art date
Application number
SE1613270A
Other languages
English (en)
Swedish (sv)
Inventor
M Gerecke
J P Zimmermann
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of SE391718B publication Critical patent/SE391718B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/32—One oxygen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SE1613270A 1969-11-29 1970-11-27 Ny optiskt aktiv lakton till anvendning vid syntes av (+)-biotin jemte forfarande for framstellning av laktonen SE391718B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1777269A CH565798A5 (es) 1969-11-29 1969-11-29

Publications (1)

Publication Number Publication Date
SE391718B true SE391718B (sv) 1977-02-28

Family

ID=4427992

Family Applications (1)

Application Number Title Priority Date Filing Date
SE1613270A SE391718B (sv) 1969-11-29 1970-11-27 Ny optiskt aktiv lakton till anvendning vid syntes av (+)-biotin jemte forfarande for framstellning av laktonen

Country Status (10)

Country Link
JP (1) JPS4932551B1 (es)
BE (1) BE759512A (es)
CA (1) CA983938A (es)
CH (1) CH565798A5 (es)
DE (1) DE2058248C3 (es)
DK (1) DK143109C (es)
FR (1) FR2077539B1 (es)
GB (1) GB1287839A (es)
NL (1) NL159385B (es)
SE (1) SE391718B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3268046D1 (en) * 1981-12-07 1986-01-30 Hoffmann La Roche Process for the preparation of an optically active lactone, and starting products for the process
DE3150723A1 (de) * 1981-12-22 1983-06-30 Basf Ag, 6700 Ludwigshafen Verbessertes verfahren zur herstellung von 1,3-disubstituierten 4,5-cis-dicarboxy-2-imidazolidonen
CH670644A5 (es) * 1986-12-18 1989-06-30 Lonza Ag
CH671227A5 (es) * 1986-12-02 1989-08-15 Lonza Ag
US5162540A (en) * 1986-12-18 1992-11-10 Lonza Ltd. Process for the production of (+) biotin
FI95034C (fi) * 1989-03-15 1995-12-11 Lonza Ag Menetelmä 1,3-substituoidun tetrahydro-1H-tieno/3,4-d/-imidatsol-2(3H)-on-4-ylideenipentaanihappoesterin valmistamiseksi
FI935609A (fi) * 1992-12-18 1994-06-19 Lonza Ag Dihydrofuroimidatsolijohdannaisten asymmetrinen hydraus
ES2088703T3 (es) * 1993-04-20 1996-08-16 Lonza Ag Hidrogenacion asimetrica de derivados del furoimidazol.
CA2122511A1 (en) * 1993-05-14 1994-11-15 John Mcgarrity Asymmetric hydrogenation of furoimidazole derivatives
DE10033284A1 (de) * 2000-07-07 2002-01-17 Merck Patent Gmbh Verfahren zur Herstellung von (+)-Biotin
TW200300676A (en) 2001-12-04 2003-06-16 Tanabe Seiyaku Co Biotin intermediate and its production
CN113121549B (zh) * 2019-12-31 2022-08-26 江西天新药业股份有限公司 立体选择性合成手性内酯的方法和手性化合物及其应用

Also Published As

Publication number Publication date
NL159385B (nl) 1979-02-15
JPS4932551B1 (es) 1974-08-31
BE759512A (fr) 1971-05-27
CH565798A5 (es) 1975-08-29
NL7015355A (es) 1971-06-02
FR2077539A1 (es) 1971-10-29
CA983938A (en) 1976-02-17
DE2058248B2 (de) 1980-04-10
DK143109B (da) 1981-03-30
FR2077539B1 (es) 1973-02-02
DK143109C (da) 1981-09-21
DE2058248C3 (de) 1980-12-18
DE2058248A1 (de) 1971-06-09
GB1287839A (es) 1972-09-06

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