SE381673B - Framstellning av en ny proteasinhiberande substans, kallad pepstatin, med angiven formel, genom odling av streptomyces testaceus eller streptomyces argenteolus var. toyonakensis - Google Patents
Framstellning av en ny proteasinhiberande substans, kallad pepstatin, med angiven formel, genom odling av streptomyces testaceus eller streptomyces argenteolus var. toyonakensisInfo
- Publication number
- SE381673B SE381673B SE7008222A SE822270A SE381673B SE 381673 B SE381673 B SE 381673B SE 7008222 A SE7008222 A SE 7008222A SE 822270 A SE822270 A SE 822270A SE 381673 B SE381673 B SE 381673B
- Authority
- SE
- Sweden
- Prior art keywords
- streptomyces
- toyonakensis
- proteas
- pepstatin
- cultivation
- Prior art date
Links
- 241000208465 Proteaceae Species 0.000 title 1
- 241000187747 Streptomyces Species 0.000 title 1
- 241000958254 Streptomyces argenteolus Species 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 title 1
- 229950000964 pepstatin Drugs 0.000 title 1
- 108010091212 pepstatin Proteins 0.000 title 1
- FAXGPCHRFPCXOO-LXTPJMTPSA-N pepstatin A Chemical compound OC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)NC(=O)CC(C)C FAXGPCHRFPCXOO-LXTPJMTPSA-N 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 239000000126 substance Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/8142—Aspartate protease (E.C. 3.4.23) inhibitors, e.g. HIV protease inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/02—Linear peptides containing at least one abnormal peptide link
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/803—Physical recovery methods, e.g. chromatography, grinding
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/886—Streptomyces
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- AIDS & HIV (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4616669 | 1969-06-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE381673B true SE381673B (sv) | 1975-12-15 |
Family
ID=12739413
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7008222A SE381673B (sv) | 1969-06-13 | 1970-06-12 | Framstellning av en ny proteasinhiberande substans, kallad pepstatin, med angiven formel, genom odling av streptomyces testaceus eller streptomyces argenteolus var. toyonakensis |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US3740319A (pm) |
| AT (1) | AT295454B (pm) |
| AU (1) | AU1584970A (pm) |
| BE (1) | BE751931A (pm) |
| CA (1) | CA928238A (pm) |
| CH (1) | CH550247A (pm) |
| CS (1) | CS171685B2 (pm) |
| DE (1) | DE2028403C3 (pm) |
| DK (1) | DK128124B (pm) |
| ES (1) | ES380545A1 (pm) |
| FI (2) | FI47498B (pm) |
| FR (1) | FR2052964B1 (pm) |
| GB (1) | GB1314231A (pm) |
| IE (1) | IE34196B1 (pm) |
| IL (1) | IL34543A (pm) |
| LU (1) | LU61119A1 (pm) |
| NL (1) | NL166279C (pm) |
| NO (1) | NO129682B (pm) |
| PH (2) | PH9382A (pm) |
| PL (1) | PL81272B1 (pm) |
| RO (1) | RO71556B (pm) |
| SE (1) | SE381673B (pm) |
| YU (1) | YU35272B (pm) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5022116B1 (pm) * | 1970-04-28 | 1975-07-28 | ||
| JPS5434837B2 (pm) * | 1972-02-08 | 1979-10-29 | ||
| DK132899C (da) * | 1972-04-07 | 1976-07-26 | Takeda Chemical Industries Ltd | Fremgangsmade til fremstilling af de proteaseinhiberende stoffer pepsinostreptiner eller salte deraf |
| US3963579A (en) * | 1973-10-17 | 1976-06-15 | Sanraku-Ocean Co., Ltd. | Microbiological process for the production of pepstatins |
| US4206283A (en) * | 1975-09-12 | 1980-06-03 | Sumitomo Chemical Company, Limited | Protease inhibitors |
| US4101650A (en) * | 1977-04-06 | 1978-07-18 | Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai | Pepstatin floating minicapsules |
| US5833946A (en) * | 1995-06-06 | 1998-11-10 | Bayer Corporation | Dissemination of fungal infections: animal model and method of prophylaxis |
| GB0807621D0 (en) * | 2008-04-25 | 2008-06-04 | Ineos Healthcare Ltd | Use |
-
1970
- 1970-05-14 US US00037165A patent/US3740319A/en not_active Expired - Lifetime
- 1970-05-18 IE IE644/70A patent/IE34196B1/xx unknown
- 1970-05-18 IL IL34543A patent/IL34543A/xx unknown
- 1970-05-18 GB GB2392870A patent/GB1314231A/en not_active Expired
- 1970-06-02 PH PH11496*UA patent/PH9382A/en unknown
- 1970-06-03 AU AU15849/70A patent/AU1584970A/en not_active Expired
- 1970-06-04 AT AT500570A patent/AT295454B/de not_active IP Right Cessation
- 1970-06-05 CS CS3969*BA patent/CS171685B2/cs unknown
- 1970-06-08 YU YU1462/70A patent/YU35272B/xx unknown
- 1970-06-08 ES ES380545A patent/ES380545A1/es not_active Expired
- 1970-06-09 DE DE2028403A patent/DE2028403C3/de not_active Expired
- 1970-06-12 CA CA085332A patent/CA928238A/en not_active Expired
- 1970-06-12 FI FI01670/70A patent/FI47498B/fi active
- 1970-06-12 DK DK304570AA patent/DK128124B/da not_active IP Right Cessation
- 1970-06-12 FR FR7021557A patent/FR2052964B1/fr not_active Expired
- 1970-06-12 SE SE7008222A patent/SE381673B/xx unknown
- 1970-06-12 NL NL7008657.A patent/NL166279C/xx not_active IP Right Cessation
- 1970-06-12 NO NO02289/70A patent/NO129682B/no unknown
- 1970-06-12 LU LU61119D patent/LU61119A1/xx unknown
- 1970-06-12 PL PL1970141274A patent/PL81272B1/pl unknown
- 1970-06-12 CH CH894270A patent/CH550247A/xx not_active IP Right Cessation
- 1970-06-12 BE BE751931D patent/BE751931A/xx not_active IP Right Cessation
- 1970-06-12 FI FI701670A patent/FI47498C/fi active
- 1970-06-13 RO RO76141A patent/RO71556B/ro unknown
-
1974
- 1974-07-09 PH PH16026A patent/PH10881A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GB1314231A (en) | 1973-04-18 |
| IL34543A0 (en) | 1970-07-19 |
| YU35272B (en) | 1980-10-31 |
| US3740319A (en) | 1973-06-19 |
| FI47498B (pm) | 1973-08-31 |
| NL166279B (nl) | 1981-02-16 |
| PH9382A (en) | 1975-10-22 |
| LU61119A1 (pm) | 1970-08-12 |
| FI47498C (fi) | 1973-12-10 |
| RO71556B (ro) | 1984-07-30 |
| CS171685B2 (pm) | 1976-10-29 |
| PH10881A (en) | 1977-09-26 |
| FR2052964A1 (pm) | 1971-04-16 |
| DE2028403B2 (de) | 1975-04-24 |
| CH550247A (de) | 1974-06-14 |
| AU1584970A (en) | 1971-12-09 |
| IL34543A (en) | 1974-03-14 |
| CA928238A (en) | 1973-06-12 |
| DK128124B (da) | 1974-03-04 |
| DE2028403C3 (de) | 1975-11-27 |
| FR2052964B1 (pm) | 1974-10-11 |
| YU146270A (en) | 1980-04-30 |
| NL7008657A (pm) | 1970-12-15 |
| ES380545A1 (es) | 1972-10-01 |
| IE34196L (en) | 1970-12-13 |
| BE751931A (fr) | 1970-11-16 |
| PL81272B1 (pm) | 1975-08-30 |
| AT295454B (de) | 1972-01-10 |
| NL166279C (nl) | 1981-07-15 |
| NO129682B (pm) | 1974-05-13 |
| RO71556A (ro) | 1984-05-23 |
| IE34196B1 (en) | 1975-03-05 |
| DE2028403A1 (de) | 1971-01-28 |
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