SE342043B - - Google Patents

Info

Publication number
SE342043B
SE342043B SE2047/68A SE204768A SE342043B SE 342043 B SE342043 B SE 342043B SE 2047/68 A SE2047/68 A SE 2047/68A SE 204768 A SE204768 A SE 204768A SE 342043 B SE342043 B SE 342043B
Authority
SE
Sweden
Application number
SE2047/68A
Inventor
K Hoegerle
E Habicht
Original Assignee
Geigy Ag J R
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Geigy Ag J R filed Critical Geigy Ag J R
Publication of SE342043B publication Critical patent/SE342043B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D203/00Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D203/04Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D203/06Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D203/08Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16Benzazepines; Hydrogenated benzazepines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Drawers Of Furniture (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
SE2047/68A 1967-02-17 1968-02-16 SE342043B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH238667A CH481110A (de) 1967-02-17 1967-02-17 Verfahren zur Herstellung von 1,2,4,5-Tetrahydro-3-azepinen
CH1167167A CH488705A (de) 1967-02-17 1967-08-18 Verfahren zur Herstellung eines neuen Tetrahydroazepinderivates

Publications (1)

Publication Number Publication Date
SE342043B true SE342043B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1972-01-24

Family

ID=25690322

Family Applications (1)

Application Number Title Priority Date Filing Date
SE2047/68A SE342043B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1967-02-17 1968-02-16

Country Status (13)

Country Link
US (1) US3652543A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) AT275533B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE (1) BE710872A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (2) CH481110A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (2) DE1668915A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK115473B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES350574A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (2) FR1561479A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (2) GB1222397A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL29485A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NL (1) NL6802257A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO124369B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SE (1) SE342043B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT289812B (de) * 1968-08-09 1971-05-10 Geigy Ag J R Verfahren zur Herstellung des neuen 2-Methyl-7-chlor-2,3,4,5-tetrahydro-1H-3-benzazepins sowie seiner Säureadditionssalze
DE2016136A1 (de) * 1970-04-04 1971-10-14 C H Boehnnger Sohn, 6507 Ingel heim Neue 7 Acyl 1,2,4,5 tetrahydro (3H) 3 benzazepine
DE2143204C3 (de) * 1971-08-28 1979-09-27 Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler, 6000 Frankfurt N-Fluoralkyl-phenylisopropylamin-Derivate und deren Salze, Verfahren zu deren Herstellung und Arzneimittel auf deren Basis
FR2171879A1 (en) * 1972-02-14 1973-09-28 Pennwalt Corp 1,2,4,5-tetrahydro-3h-3-benzazepines - analgesics narcotic antagonists, antihistamines etc
DE3272044D1 (de) * 1981-11-27 1986-08-21 Smithkline Beckman Corp 3-benzazepines as alpha-2 antagonists
US4541954A (en) * 1984-09-05 1985-09-17 Smithkline Beckman Corporation Method for preparing 6-chloro-N-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine
US4973586A (en) * 1986-01-16 1990-11-27 Schering Corporation Fused benzazepines, compositions of, and medical use thereof
HU199805B (en) * 1986-01-16 1990-03-28 Schering Corp Process for producing condensed benzazepine derivatives and pharmaceutical compositions comprising such compounds
US5302716A (en) * 1986-01-16 1994-04-12 Schering Corporation Fused benzazepines
US5015639A (en) * 1987-03-27 1991-05-14 Schering Corporation Substituted benzazepines, their preparation and pharmaceutical compositions containing them
AU617651B2 (en) * 1987-07-15 1991-12-05 Schering Corporation Fused benzazepines
WO1991011437A1 (en) * 1990-02-02 1991-08-08 Schering Corporation 4,5-cycloalkano-3-benzazepin-7-ol-derivatives and their use
US6953787B2 (en) * 2002-04-12 2005-10-11 Arena Pharmaceuticals, Inc. 5HT2C receptor modulators
US20030220661A1 (en) * 2002-05-21 2003-11-27 Heartstent Corporation Transmyocardial implant delivery system
US7704993B2 (en) * 2003-06-17 2010-04-27 Arena Pharmaceuticals, Inc. Benzazepine derivatives and methods of prophylaxis or treatment of 5ht2c receptor associated diseases
EA016485B1 (ru) * 2003-06-17 2012-05-30 Арена Фармасьютикалз, Инк. Способы получения 3-бензазепинов
US20080009478A1 (en) * 2003-10-22 2008-01-10 Arena Pharmaceuticals, Inc. Benzazepine Derivatives and Methods of Prophylaxis or Treatment of 5Ht2c Receptor Associated Diseases
US20070275949A1 (en) * 2003-10-22 2007-11-29 Arena Pharmaceuticals, Inc. Benzazepine Derivatives and Methods of Prophylaxis or Treatment of 5Ht2C Receptor Associated Diseases
WO2006069363A2 (en) 2004-12-21 2006-06-29 Arena Pharmaceuticals, Inc. Crystalline forms of (r)-8-chloro-1-methyl- 2,3,4,5-tetrahydro-1h-3-benzazepine hydrochloride
JP4886700B2 (ja) 2004-12-23 2012-02-29 アリーナ ファーマシューティカルズ, インコーポレイテッド 5ht2cレセプターモジュレーターの組成物およびその使用方法
EP2471779A1 (en) 2006-04-03 2012-07-04 Arena Pharmaceuticals, Inc. Process for the resolution of a mixture of (R)- and (S)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine
JP5404414B2 (ja) * 2006-12-05 2014-01-29 アリーナ ファーマシューティカルズ, インコーポレイテッド (r)−8−クロロ−1−メチル−2,3,4,5−テトラヒドロ−1h−3−ベンゾアゼピンおよびその中間体を調製するための方法
JP5491421B2 (ja) * 2008-03-04 2014-05-14 アリーナ ファーマシューティカルズ, インコーポレイテッド 5−ht2cアゴニストである(r)−8−クロロ−1−メチル−2,3,4,5−テトラヒドロ−1h−3−ベンゾアゼピンに関連する中間体の調製のためのプロセス
EP2443080A2 (en) 2009-06-18 2012-04-25 Arena Pharmaceuticals, Inc. Process for the preparation of 5-ht2c receptor agonists
US20120253036A1 (en) 2009-12-11 2012-10-04 Yukinori Nagakura Agent for treating fibromyalgia
KR20130112848A (ko) 2010-06-02 2013-10-14 아레나 파마슈티칼스, 인크. 5-ht2c 수용체 아고니스트의 제조 방법
SG10201506865WA (en) 2010-09-01 2015-10-29 Arena Pharm Inc Non-hygroscopic salts of 5-ht2c agonists
WO2012030938A1 (en) 2010-09-01 2012-03-08 Arena Pharmaceuticals, Inc. Salts of lorcaserin with optically active acids
MX2013002418A (es) 2010-09-01 2013-08-01 Arena Pharm Inc Administracion de lorcaserina a individuos con daño renal.
CA2808912C (en) 2010-09-01 2019-09-17 Zezhi Jesse Shao Modified-release dosage forms of 5-ht2c agonists useful for weight management
AR088670A1 (es) 2012-10-09 2014-06-25 Arena Pharm Inc Metodo de control del peso

Also Published As

Publication number Publication date
FR1560654A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1969-03-21
DE1695124A1 (de) 1970-08-20
GB1222397A (en) 1971-02-10
NL6802257A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1968-08-19
BE710872A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1968-08-16
CH481110A (de) 1969-11-15
DK115473B (da) 1969-10-13
AT275533B (de) 1969-10-27
NO124369B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1972-04-10
FR1561479A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1969-03-28
GB1221324A (en) 1971-02-03
ES350574A1 (es) 1969-11-16
IL29485A (en) 1971-07-28
US3652543A (en) 1972-03-28
DE1668915A1 (de) 1972-03-09
CH488705A (de) 1970-04-15

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