SE329398B - - Google Patents
Info
- Publication number
- SE329398B SE329398B SE07693/68A SE769368A SE329398B SE 329398 B SE329398 B SE 329398B SE 07693/68 A SE07693/68 A SE 07693/68A SE 769368 A SE769368 A SE 769368A SE 329398 B SE329398 B SE 329398B
- Authority
- SE
- Sweden
- Prior art keywords
- july
- alpha
- hydroxy
- butyl
- pharmaceutically acceptable
- Prior art date
Links
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 2
- DNZPLHRZXUJATK-UHFFFAOYSA-N 2-sulfanylidene-5-[[5-[2-(trifluoromethyl)phenyl]furan-2-yl]methyl]-1,3-diazinane-4,6-dione Chemical class FC(F)(F)C1=CC=CC=C1C(O1)=CC=C1CC1C(=O)NC(=S)NC1=O DNZPLHRZXUJATK-UHFFFAOYSA-N 0.000 abstract 1
- RMMXTBMQSGEXHJ-UHFFFAOYSA-N Aminophenazone Chemical compound O=C1C(N(C)C)=C(C)N(C)N1C1=CC=CC=C1 RMMXTBMQSGEXHJ-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 229960000212 aminophenazone Drugs 0.000 abstract 1
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000002294 steroidal antiinflammatory agent Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 230000003424 uricosuric effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/60—Three or more oxygen or sulfur atoms
- C07D239/62—Barbituric acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1,159,271. Anti-inflammatory &c., medicines. TAKEDA CHEMICAL INDUSTRIES Ltd. 20 July, 1966 [21 July, 1965; 7 May, 1966], No. 32641/66. Heading A5B [Also in Division C2] Pharmaceutical compositions having antiinflammatory and uricosuric activity comprise, as active ingredient, at least one 1,5-disubstituted barbituric acid derivative of the general formula wherein R 1 is a S - hydroxy - n - butyl, α - hydroxy - n - butyl or α - carboxypropyl group and R 2 is a cyclohexyl or phenyl group, or pharmaceutically acceptable base addition salt thereof, optionally together with aminopyrine or a steroidal anti-inflammatory agent and optionally together with a pharmaceutically acceptable carrier therefor. The compositions may be administered orally, rectally or parenterally.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4438765 | 1965-07-21 | ||
| JP2904466 | 1966-05-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE329398B true SE329398B (en) | 1970-10-12 |
Family
ID=26367190
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE07693/68A SE329398B (en) | 1965-07-21 | 1966-07-20 | |
| SE07692/68A SE347973B (en) | 1965-07-21 | 1966-07-20 | |
| SE9942/66A SE320076B (en) | 1965-07-21 | 1966-07-20 | |
| SE03339/71A SE357200B (en) | 1965-07-21 | 1966-07-20 | |
| SE03338/71A SE357747B (en) | 1965-07-21 | 1966-07-20 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE07692/68A SE347973B (en) | 1965-07-21 | 1966-07-20 | |
| SE9942/66A SE320076B (en) | 1965-07-21 | 1966-07-20 | |
| SE03339/71A SE357200B (en) | 1965-07-21 | 1966-07-20 | |
| SE03338/71A SE357747B (en) | 1965-07-21 | 1966-07-20 |
Country Status (7)
| Country | Link |
|---|---|
| BE (1) | BE684410A (en) |
| DK (1) | DK117230B (en) |
| ES (1) | ES329306A1 (en) |
| FR (1) | FR6406M (en) |
| GB (1) | GB1159271A (en) |
| NL (1) | NL6610290A (en) |
| SE (5) | SE329398B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1599518A (en) * | 1977-02-21 | 1981-10-07 | Ici Ltd | 1,3,5-triazine-2,6-diones and pharmaceutical compositions thereof |
-
1966
- 1966-07-20 DK DK377066AA patent/DK117230B/en unknown
- 1966-07-20 SE SE07693/68A patent/SE329398B/xx unknown
- 1966-07-20 SE SE07692/68A patent/SE347973B/xx unknown
- 1966-07-20 BE BE684410D patent/BE684410A/xx unknown
- 1966-07-20 ES ES0329306A patent/ES329306A1/en not_active Expired
- 1966-07-20 GB GB32641/66A patent/GB1159271A/en not_active Expired
- 1966-07-20 SE SE9942/66A patent/SE320076B/xx unknown
- 1966-07-20 SE SE03339/71A patent/SE357200B/xx unknown
- 1966-07-20 SE SE03338/71A patent/SE357747B/xx unknown
- 1966-07-21 NL NL6610290A patent/NL6610290A/xx unknown
- 1966-10-19 FR FR70168A patent/FR6406M/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| NL6610290A (en) | 1967-01-23 |
| ES329306A1 (en) | 1967-05-01 |
| GB1159271A (en) | 1969-07-23 |
| DK117230B (en) | 1970-03-31 |
| SE357747B (en) | 1973-07-09 |
| SE347973B (en) | 1972-08-21 |
| SE357200B (en) | 1973-06-18 |
| BE684410A (en) | 1967-01-03 |
| DE1620556A1 (en) | 1970-04-16 |
| SE320076B (en) | 1970-02-02 |
| FR6406M (en) | 1968-10-28 |
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