GB1305488A - - Google Patents
Info
- Publication number
- GB1305488A GB1305488A GB4489570A GB4489570A GB1305488A GB 1305488 A GB1305488 A GB 1305488A GB 4489570 A GB4489570 A GB 4489570A GB 4489570 A GB4489570 A GB 4489570A GB 1305488 A GB1305488 A GB 1305488A
- Authority
- GB
- United Kingdom
- Prior art keywords
- iii
- sept
- halogen
- alkyl
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1305488 Phenylthioaralkylamines and phenylthioaralkanamides MERCK & CO inc 21 Sept 1970 [22 Sept 1969] 44895/70 Heading C2C Novel compounds (II) and (III) (including salts of III) where m is 0 to 4, R 2 and R 3 are H, alkyl, aralkyl, alkenyl or alkynyl or R 2 and R 3 are joined together directly or are linked through N, O or S to form together with the N to which they are both attached, a heterocyclic ring of 5 or 6 atoms and X and X<SP>1</SP> are H, halogen, alkyl, alkoxy, perfluoroalkyl, alkylthio, alkylsulphonyl or dialkylsulphamoyl (more than one substituent can be present in each benzene ring), provided that when m is 1 and X<SP>1</SP>, R 2 and R 3 are all H, X is not halogen, are made from compounds (I) utilizing NHR 2 R 3 and reduction. Pharmaceutical preparations possessing antiarrhythmic activity contain (III) as active ingredient; administration may be orally or parenterally.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86007669A | 1969-09-22 | 1969-09-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1305488A true GB1305488A (en) | 1973-01-31 |
Family
ID=25332438
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4489570A Expired GB1305488A (en) | 1969-09-22 | 1970-09-21 |
Country Status (10)
| Country | Link |
|---|---|
| JP (1) | JPS501260B1 (en) |
| CA (1) | CA977372A (en) |
| CH (1) | CH547784A (en) |
| DE (1) | DE2046512A1 (en) |
| DK (1) | DK129037B (en) |
| FR (1) | FR2070081B1 (en) |
| GB (1) | GB1305488A (en) |
| NL (1) | NL7013205A (en) |
| NO (1) | NO126857B (en) |
| SE (1) | SE366737B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4091100A (en) | 1975-07-21 | 1978-05-23 | Burroughs Wellcome Co. | Sulfide compounds |
-
1970
- 1970-09-07 NL NL7013205A patent/NL7013205A/xx unknown
- 1970-09-17 CA CA093,433A patent/CA977372A/en not_active Expired
- 1970-09-18 SE SE1271970A patent/SE366737B/xx unknown
- 1970-09-21 JP JP8288470A patent/JPS501260B1/ja active Pending
- 1970-09-21 NO NO357270A patent/NO126857B/no unknown
- 1970-09-21 DK DK482270A patent/DK129037B/en unknown
- 1970-09-21 GB GB4489570A patent/GB1305488A/en not_active Expired
- 1970-09-21 FR FR7034147A patent/FR2070081B1/fr not_active Expired
- 1970-09-21 DE DE19702046512 patent/DE2046512A1/en not_active Withdrawn
- 1970-09-22 CH CH1402170A patent/CH547784A/en not_active IP Right Cessation
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4091100A (en) | 1975-07-21 | 1978-05-23 | Burroughs Wellcome Co. | Sulfide compounds |
| US4095027A (en) | 1975-07-21 | 1978-06-13 | Burroughs Wellcome Co. | 2-Carbalkoxy-2'-aminocarbonyldiphenyl sulfides |
| US4103020A (en) | 1975-07-21 | 1978-07-25 | Burroughs Wellcome Co. | Sulfide compounds as antidepressants |
| US4123555A (en) | 1975-07-21 | 1978-10-31 | Burroughs Wellcome Co. | Sulfide compounds and methods and compositions for treating depression |
Also Published As
| Publication number | Publication date |
|---|---|
| NO126857B (en) | 1973-04-02 |
| CH547784A (en) | 1974-04-11 |
| CA977372A (en) | 1975-11-04 |
| JPS501260B1 (en) | 1975-01-16 |
| DE2046512A1 (en) | 1971-04-01 |
| FR2070081B1 (en) | 1975-06-06 |
| SE366737B (en) | 1974-05-06 |
| NL7013205A (en) | 1971-03-24 |
| FR2070081A1 (en) | 1971-09-10 |
| DK129037B (en) | 1974-08-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |