SE0951009A1 - Anordning och förfarande för rening och anrikning av biologiskt prov - Google Patents

Anordning och förfarande för rening och anrikning av biologiskt prov Download PDF

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Publication number
SE0951009A1
SE0951009A1 SE0951009A SE0951009A SE0951009A1 SE 0951009 A1 SE0951009 A1 SE 0951009A1 SE 0951009 A SE0951009 A SE 0951009A SE 0951009 A SE0951009 A SE 0951009A SE 0951009 A1 SE0951009 A1 SE 0951009A1
Authority
SE
Sweden
Prior art keywords
filter
sample
filtration unit
suction
fluid communication
Prior art date
Application number
SE0951009A
Other languages
English (en)
Swedish (sv)
Inventor
Christer Ericsson
Juan Castro
Lars Waennmar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to SE0951009A priority Critical patent/SE0951009A1/sv
Priority to CA2783007A priority patent/CA2783007A1/en
Priority to KR1020127019068A priority patent/KR20120121883A/ko
Priority to CN201080058448.9A priority patent/CN102803467B/zh
Priority to BR112012015643A priority patent/BR112012015643A2/pt
Priority to US13/517,086 priority patent/US20120270312A1/en
Priority to EP10839905.6A priority patent/EP2516619B1/en
Priority to JP2012545908A priority patent/JP2013514806A/ja
Priority to RU2012122009/10A priority patent/RU2012122009A/ru
Priority to PCT/SE2010/051473 priority patent/WO2011078784A1/en
Publication of SE0951009A1 publication Critical patent/SE0951009A1/sv

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M3/00Tissue, human, animal or plant cell, or virus culture apparatus
    • C12M3/06Tissue, human, animal or plant cell, or virus culture apparatus with filtration, ultrafiltration, inverse osmosis or dialysis means
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D35/00Filtering devices having features not specifically covered by groups B01D24/00 - B01D33/00, or for applications not specifically covered by groups B01D24/00 - B01D33/00; Auxiliary devices for filtration; Filter housing constructions
    • B01D35/20Vibrating the filters
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/02Separating microorganisms from the culture medium; Concentration of biomass
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D37/00Processes of filtration
    • B01D37/04Controlling the filtration
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00Apparatus for enzymology or microbiology
    • C12M1/02Apparatus for enzymology or microbiology with agitation means; with heat exchange means
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/02Separating microorganisms from their culture media
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0081Purging biological preparations of unwanted cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0693Tumour cells; Cancer cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00Means for mixing, agitating or circulating fluids in the vessel

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Sustainable Development (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Water Supply & Treatment (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Separation Of Solids By Using Liquids Or Pneumatic Power (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
SE0951009A 2009-12-22 2009-12-22 Anordning och förfarande för rening och anrikning av biologiskt prov SE0951009A1 (sv)

Priority Applications (10)

Application Number Priority Date Filing Date Title
SE0951009A SE0951009A1 (sv) 2009-12-22 2009-12-22 Anordning och förfarande för rening och anrikning av biologiskt prov
CA2783007A CA2783007A1 (en) 2009-12-22 2010-12-22 Device and method for biological sample purification and enrichment
KR1020127019068A KR20120121883A (ko) 2009-12-22 2010-12-22 생물학적 샘플 정제 및 농축용 장치 및 방법
CN201080058448.9A CN102803467B (zh) 2009-12-22 2010-12-22 生物样品纯化和富集的装置和方法
BR112012015643A BR112012015643A2 (pt) 2009-12-22 2010-12-22 dispositivo e método para a purificação e enriquecimento de amostras biológicas
US13/517,086 US20120270312A1 (en) 2009-12-22 2010-12-22 Device and method for biological sample purification and enrichment
EP10839905.6A EP2516619B1 (en) 2009-12-22 2010-12-22 Device and method for biological sample purification and enrichment
JP2012545908A JP2013514806A (ja) 2009-12-22 2010-12-22 生体試料の精製及び濃縮のための装置及び方法
RU2012122009/10A RU2012122009A (ru) 2009-12-22 2010-12-22 Устройство для очистки и обогащения биологических образцов и способ очистки и обогащения биологических образцов
PCT/SE2010/051473 WO2011078784A1 (en) 2009-12-22 2010-12-22 Device and method for biological sample purification and enrichment

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0951009A SE0951009A1 (sv) 2009-12-22 2009-12-22 Anordning och förfarande för rening och anrikning av biologiskt prov

Publications (1)

Publication Number Publication Date
SE0951009A1 true SE0951009A1 (sv) 2011-06-23

Family

ID=44196041

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0951009A SE0951009A1 (sv) 2009-12-22 2009-12-22 Anordning och förfarande för rening och anrikning av biologiskt prov

Country Status (10)

Country Link
US (1) US20120270312A1 (https=)
EP (1) EP2516619B1 (https=)
JP (1) JP2013514806A (https=)
KR (1) KR20120121883A (https=)
CN (1) CN102803467B (https=)
BR (1) BR112012015643A2 (https=)
CA (1) CA2783007A1 (https=)
RU (1) RU2012122009A (https=)
SE (1) SE0951009A1 (https=)
WO (1) WO2011078784A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2902476B1 (en) * 2012-09-28 2021-01-06 Sysmex Corporation Sample preparation device and cell analysis device
GB2517063B (en) * 2013-06-19 2018-02-28 Brightwake Ltd Cell collection device
CN105062874A (zh) * 2015-07-16 2015-11-18 南京大学医学院附属鼓楼医院 一种基于闭合环路的循环肿瘤细胞分离富集装置
GB2543660B (en) * 2015-10-19 2018-04-25 Cytosystems Ltd Filtration apparatus comprising two movable ports moved from a first to second position thrugh rotation of the membrane housing
CN108126522B (zh) * 2017-12-21 2020-08-18 深圳汇芯生物医疗科技有限公司 分离芯片、分离装置及分离液体样本中目标颗粒的方法
CN108841713B (zh) * 2018-06-12 2020-10-20 深圳韦拓生物科技有限公司 理化处理单个细胞的微流控芯片、微流控装置及使用其理化处理单个细胞的方法
CN111044514A (zh) * 2019-11-27 2020-04-21 爱威科技股份有限公司 一种富集方法、样本制造方法以及样本检测方法
GB202016433D0 (en) * 2020-10-16 2020-12-02 Dnae Diagnostics Ltd Improvements in or relating to fluid sample preparation

Family Cites Families (20)

* Cited by examiner, † Cited by third party
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SE430218B (sv) * 1981-12-30 1983-10-31 Blombaeck E G B Filter och sett att framstella ett sadant
US5189777A (en) * 1990-12-07 1993-03-02 Wisconsin Alumni Research Foundation Method of producing micromachined differential pressure transducers
GB9113150D0 (en) * 1991-06-18 1991-08-07 Endless Energy Ltd Backwash apparatus
FR2704432B1 (fr) * 1993-04-27 1995-06-23 Hospal Ind Dispositif d'injection de liquide dans un circuit extracorporel de sang.
JPH06327769A (ja) * 1993-05-21 1994-11-29 Terumo Corp 血漿処理装置
CA2278208C (en) * 1997-01-24 2011-09-20 Asahi Medical Co., Ltd. Cell separation method
JPH10234361A (ja) * 1997-02-24 1998-09-08 Asahi Medical Co Ltd 造血幹細胞分離・保存システム
US6693579B2 (en) * 2001-08-01 2004-02-17 Lexmark International, Inc. Method to improve sealing of ink jet printhead purge mechanism to printhead
DE60237531D1 (de) * 2001-10-11 2010-10-14 Aviva Biosciences Corp Verfahren zum trennen von seltenen zellen von fluidproben
US7651684B2 (en) * 2001-12-07 2010-01-26 Cytori Therapeutics, Inc. Methods of using adipose tissue-derived cells in augmenting autologous fat transfer
JP4653952B2 (ja) * 2001-12-07 2011-03-16 サイトリ セラピューティクス インコーポレイテッド 処理済み脂肪吸引細胞で患者を治療するためのシステムと方法
TW497494U (en) * 2001-12-28 2002-08-01 Metal Ind Redearch & Amp Dev C Fluid driven stirring device for compressing gas cleaning system
US6905594B2 (en) * 2002-10-11 2005-06-14 G6 Science Corp. Filter apparatus and methods to capture a desired amount of material from a sample suspension for monolayer deposition, analysis or other uses
US7338637B2 (en) * 2003-01-31 2008-03-04 Hewlett-Packard Development Company, L.P. Microfluidic device with thin-film electronic devices
EP1683857B1 (en) * 2003-10-10 2011-02-16 Asahi Kasei Kuraray Medical Co., Ltd. Method of preparing cell concentrate and cell composition
US7494809B2 (en) 2004-11-09 2009-02-24 Visiongate, Inc. Automated cell sample enrichment preparation method
US7846393B2 (en) 2005-04-21 2010-12-07 California Institute Of Technology Membrane filter for capturing circulating tumor cells
RU2480522C2 (ru) * 2007-03-02 2013-04-27 СМИТ ЭНД НЕФЬЮ ПиЭлСи Устройство и способ выделения твердой фракции из образца текучей среды
GB0800311D0 (en) * 2008-01-09 2008-02-20 Cytosystems Ltd Apparatus and method for filtering biological material
JP5336109B2 (ja) 2008-05-30 2013-11-06 旭化成メディカル株式会社 単核細胞と血小板の濃縮方法

Also Published As

Publication number Publication date
KR20120121883A (ko) 2012-11-06
JP2013514806A (ja) 2013-05-02
CN102803467B (zh) 2015-07-22
CA2783007A1 (en) 2011-06-30
EP2516619B1 (en) 2017-01-25
EP2516619A1 (en) 2012-10-31
WO2011078784A1 (en) 2011-06-30
RU2012122009A (ru) 2014-01-27
EP2516619A4 (en) 2014-03-05
BR112012015643A2 (pt) 2017-05-09
US20120270312A1 (en) 2012-10-25
CN102803467A (zh) 2012-11-28

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