SE0002202D0 - New peptides - Google Patents

New peptides

Info

Publication number
SE0002202D0
SE0002202D0 SE0002202A SE0002202A SE0002202D0 SE 0002202 D0 SE0002202 D0 SE 0002202D0 SE 0002202 A SE0002202 A SE 0002202A SE 0002202 A SE0002202 A SE 0002202A SE 0002202 D0 SE0002202 D0 SE 0002202D0
Authority
SE
Sweden
Prior art keywords
new peptides
alkylating
invention refers
peptides
new
Prior art date
Application number
SE0002202A
Other languages
English (en)
Swedish (sv)
Inventor
Rolf Lewensohn
Joakim Gullbo
Rolf Larsson
Hans Ehrsson
Kristina Luthman
Original Assignee
Karolinska Innovations Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Karolinska Innovations Ab filed Critical Karolinska Innovations Ab
Priority to SE0002202A priority Critical patent/SE0002202D0/xx
Publication of SE0002202D0 publication Critical patent/SE0002202D0/xx
Priority to DK01938945.1T priority patent/DK1290011T3/da
Priority to AT01938945T priority patent/ATE458746T1/de
Priority to PT01938945T priority patent/PT1290011E/pt
Priority to DE60141398T priority patent/DE60141398D1/de
Priority to AU2001264515A priority patent/AU2001264515A1/en
Priority to CA2408501A priority patent/CA2408501C/fr
Priority to US10/297,588 priority patent/US6992207B2/en
Priority to JP2002510508A priority patent/JP4798930B2/ja
Priority to ES01938945T priority patent/ES2341702T3/es
Priority to PCT/SE2001/001318 priority patent/WO2001096367A1/fr
Priority to EP01938945A priority patent/EP1290011B1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0827—Tripeptides containing heteroatoms different from O, S, or N
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
SE0002202A 2000-06-13 2000-06-13 New peptides SE0002202D0 (sv)

Priority Applications (12)

Application Number Priority Date Filing Date Title
SE0002202A SE0002202D0 (sv) 2000-06-13 2000-06-13 New peptides
EP01938945A EP1290011B1 (fr) 2000-06-13 2001-06-11 Derives de melphalan et leur utilisation comme produits chimiotherapeutiques contre le cancer
DE60141398T DE60141398D1 (de) 2000-06-13 2001-06-11 Melphalan-derivate und ihre verwendung als chemotherapeutika gegen krebs
AT01938945T ATE458746T1 (de) 2000-06-13 2001-06-11 Melphalan-derivate und ihre verwendung als chemotherapeutika gegen krebs
PT01938945T PT1290011E (pt) 2000-06-13 2001-06-11 Derivados de melfalano e seu uso como drogas quimioterapêuticas de cancro
DK01938945.1T DK1290011T3 (da) 2000-06-13 2001-06-11 Melphalan-derivater og deres anvendelse som cancer-kemoterapeutiske lægemidler
AU2001264515A AU2001264515A1 (en) 2000-06-13 2001-06-11 Melphalan derivatives and their use as cancer chemotherapeutic drugs
CA2408501A CA2408501C (fr) 2000-06-13 2001-06-11 Derives de melphalan et leur utilisation comme produits chimiotherapeutiques contre le cancer
US10/297,588 US6992207B2 (en) 2000-06-13 2001-06-11 Melphalan derivatives and their use as cancer chemotherapeutic drugs
JP2002510508A JP4798930B2 (ja) 2000-06-13 2001-06-11 メルファラン誘導体及び癌の化学療法薬としてのその使用
ES01938945T ES2341702T3 (es) 2000-06-13 2001-06-11 Derivados de melfalan y su uso como farmacos quimioterapeuticos del cancer.
PCT/SE2001/001318 WO2001096367A1 (fr) 2000-06-13 2001-06-11 Derives de melphalan et leur utilisation comme produits chimiotherapeutiques contre le cancer

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0002202A SE0002202D0 (sv) 2000-06-13 2000-06-13 New peptides

Publications (1)

Publication Number Publication Date
SE0002202D0 true SE0002202D0 (sv) 2000-06-13

Family

ID=20280067

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0002202A SE0002202D0 (sv) 2000-06-13 2000-06-13 New peptides

Country Status (10)

Country Link
EP (1) EP1290011B1 (fr)
JP (1) JP4798930B2 (fr)
AT (1) ATE458746T1 (fr)
AU (1) AU2001264515A1 (fr)
CA (1) CA2408501C (fr)
DK (1) DK1290011T3 (fr)
ES (1) ES2341702T3 (fr)
PT (1) PT1290011E (fr)
SE (1) SE0002202D0 (fr)
WO (1) WO2001096367A1 (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1374907A3 (fr) * 2002-06-24 2004-01-07 Ghanem Elias c/o Institut Jules Bordet Ghanem Système véhiculaire et de délivrance de médicaments
DE10239832A1 (de) * 2002-08-29 2004-03-18 Lipal Biochemicals AG c/o University of Zurich Sarcolysyl-Derivate und Verfahren zu deren Herstellung
WO2011011865A1 (fr) * 2009-07-29 2011-02-03 3R Valo, S.E.C. Agents anticancéreux à base de dérivés d’acides aminés
WO2011078782A1 (fr) * 2009-12-22 2011-06-30 Oncopeptides Ab Composition contenant des dérivés du melphalan et de la gemcitabine ou de l'étoposide utile dans le traitement du cancer
US20140128462A1 (en) * 2011-04-28 2014-05-08 Oncopeptides Ab Lyophilized preparation of cytotoxic dipeptides
KR102122429B1 (ko) * 2011-04-28 2020-06-12 온코펩타이드즈 아베 세포독성 디펩티드의 동결건조 제제
LT2928463T (lt) * 2012-10-26 2020-02-10 Oncopeptides Ab Liofilizuoti melfalano flufenamido preparatai
US10285946B2 (en) * 2012-10-26 2019-05-14 Oncopeptides Ab Lyophilized preparations of melphalan flufenamide
GB201507903D0 (en) * 2015-05-08 2015-06-24 Oncopeptides Ab Process for preparation of nitrogen mustard derivatives
GB201521217D0 (en) 2015-12-01 2016-01-13 Oncopeptides Ab Dosage regimens
CN108864251B (zh) * 2018-06-30 2022-06-14 大连理工大学 一类氨肽酶n激活的药物前体化合物及其制备方法和应用
DK3866931T3 (da) 2018-10-18 2023-04-24 Oncopeptides Ab Forbindelser indeholdende deuterium
US20220193019A1 (en) 2019-04-03 2022-06-23 Oncopeptides Ab Treatment of al amyloidosis with melflufen
GB201905477D0 (en) 2019-04-17 2019-05-29 Oncopeptides Ab Novel formulations
WO2021053185A1 (fr) 2019-09-20 2021-03-25 Oncopeptides Ab Formulations de melflufène et leur utilisation dans le traitement ou la prophylaxie d'un ostéosarcome
WO2022167087A1 (fr) * 2021-02-05 2022-08-11 Oncopeptides Ab Dipeptides cytotoxiques renforcés par une peptidase
EP4083052A1 (fr) 2021-04-29 2022-11-02 BKmdcl AB Conjugués peptidiques de melphalan pour le traitement du cancer
EP4347615A1 (fr) 2021-06-01 2024-04-10 Synthon B.V. Procédé de préparation de melflufène ou d'un sel de celui-ci
WO2023281007A1 (fr) 2021-07-08 2023-01-12 Oncopeptides Ab Melflufène destiné à être utilisé dans le traitement du myélome multiple
GB202109894D0 (en) 2021-07-08 2021-08-25 Oncopeptides Ab Novel treatments
GB202109896D0 (en) 2021-07-08 2021-08-25 Oncopeptides Ab Novel treatments
GB202109895D0 (en) 2021-07-08 2021-08-25 Oncopeptides Ab Novel treatments
GB202204171D0 (en) 2022-03-24 2022-05-11 Oncopeptides Ab Novel formulations

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB750155A (en) 1953-03-17 1956-06-13 Nat Res Dev Substituted alanines

Also Published As

Publication number Publication date
ES2341702T3 (es) 2010-06-25
AU2001264515A1 (en) 2001-12-24
WO2001096367A1 (fr) 2001-12-20
DK1290011T3 (da) 2010-06-07
EP1290011A1 (fr) 2003-03-12
ATE458746T1 (de) 2010-03-15
JP2004503564A (ja) 2004-02-05
CA2408501C (fr) 2011-01-18
EP1290011B1 (fr) 2010-02-24
PT1290011E (pt) 2010-05-11
CA2408501A1 (fr) 2001-12-20
JP4798930B2 (ja) 2011-10-19

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