DE60141398D1 - Melphalan-derivate und ihre verwendung als chemotherapeutika gegen krebs - Google Patents

Melphalan-derivate und ihre verwendung als chemotherapeutika gegen krebs

Info

Publication number
DE60141398D1
DE60141398D1 DE60141398T DE60141398T DE60141398D1 DE 60141398 D1 DE60141398 D1 DE 60141398D1 DE 60141398 T DE60141398 T DE 60141398T DE 60141398 T DE60141398 T DE 60141398T DE 60141398 D1 DE60141398 D1 DE 60141398D1
Authority
DE
Germany
Prior art keywords
against cancer
chemotherapeutics against
melphalan derivatives
melphalan
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60141398T
Other languages
English (en)
Inventor
Rolf Lewensohn
Joakim Gullbo
Rolf Larsson
Hans Ehrsson
Kristina Luthman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oncopeptides AB
Original Assignee
Oncopeptides AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE0002202A external-priority patent/SE0002202D0/xx
Application filed by Oncopeptides AB filed Critical Oncopeptides AB
Application granted granted Critical
Publication of DE60141398D1 publication Critical patent/DE60141398D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0827—Tripeptides containing heteroatoms different from O, S, or N
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DE60141398T 2000-06-13 2001-06-11 Melphalan-derivate und ihre verwendung als chemotherapeutika gegen krebs Expired - Lifetime DE60141398D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US21122700P 2000-06-13 2000-06-13
SE0002202A SE0002202D0 (sv) 2000-06-13 2000-06-13 New peptides
PCT/SE2001/001318 WO2001096367A1 (en) 2000-06-13 2001-06-11 Melphalan derivatives and their use as cancer chemotherapeutic drugs

Publications (1)

Publication Number Publication Date
DE60141398D1 true DE60141398D1 (de) 2010-04-08

Family

ID=26655146

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60141398T Expired - Lifetime DE60141398D1 (de) 2000-06-13 2001-06-11 Melphalan-derivate und ihre verwendung als chemotherapeutika gegen krebs

Country Status (2)

Country Link
US (1) US6992207B2 (de)
DE (1) DE60141398D1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008039525A2 (en) * 2006-09-27 2008-04-03 Adherex Technologies, Inc. Cadherin antagonists in combination with anticancer agents for use in cancer treatment
WO2008060535A2 (en) * 2006-11-10 2008-05-22 Dana-Farber Cancer Institute, Inc. Use of reversine and analogs for treatment of cancer
PL3656393T3 (pl) 2011-04-28 2023-01-16 Oncopeptides Ab Liofilizowany preparat cytotoksycznych dipeptydów
KR102122429B1 (ko) * 2011-04-28 2020-06-12 온코펩타이드즈 아베 세포독성 디펩티드의 동결건조 제제
SI2928463T1 (sl) * 2012-10-26 2020-03-31 Oncopeptides Ab Liofilizirani pripravki melfalan flufenamida
GB201507903D0 (en) * 2015-05-08 2015-06-24 Oncopeptides Ab Process for preparation of nitrogen mustard derivatives

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB750155A (en) * 1953-03-17 1956-06-13 Nat Res Dev Substituted alanines
IT1134503B (it) * 1980-11-28 1986-08-13 Proter Spa Composti della diclorodietilaminofenilalanina ad azione antitumorale
US4314999A (en) * 1978-07-31 1982-02-09 Proter S.P.A. N-Acyl derivatives of glucosamine having antitumor chemotherapeutic acitivity
US4540683A (en) * 1978-07-31 1985-09-10 Proter S.P.A. In vitro and in vivo treatment of cancer cells and treatment of viruses with a tripeptide compound
US4740501A (en) * 1978-07-31 1988-04-26 Debarbieri Augusto Interference of b-type retrovirus replication with a tripeptide compound
US4216208A (en) * 1978-07-31 1980-08-05 Proter S.P.A. N-Acyl derivatives of glucosamines having antitumor chemotherapeutic activity

Also Published As

Publication number Publication date
US20040097421A1 (en) 2004-05-20
US6992207B2 (en) 2006-01-31

Similar Documents

Publication Publication Date Title
DE60139477D1 (de) 2-cyanopyrrolidin-derivate und ihre verwendung als arzneimittel
ATE394102T1 (de) Substituierte chinazolin-derivate und deren verwendung als aurora-2-kinase inhibitoren
ATE376357T1 (de) Chinolin-; isochinolin- und chinazolinoxyalkylamide und ihre verwendung als fungizide
DE60208661D1 (de) Diaminothiazole und ihre verwendung als cyclinabhängige kinase inhibitoren
ATE340160T1 (de) Picolinsäure-derivate und ihre verwendung als fungizide
DE60321558D1 (de) Chinolinderivate und deren verwendung als 5-ht6 liganden
DE60113719D1 (de) Chinuclidincarbamat derivate und deren verwendung als m3 antagonisten
ATE269701T1 (de) Gyrase-inhibitoren und ihre verwendung
EE200300071A (et) Kinasoliini derivaadid
ATE522506T1 (de) 4-aminopicolinate und ihre verwendung als herbizide
DE602004004957D1 (de) Härtbare wässrige Zusammensetzung und ihre Verwendung als Vliesstoff-Bindemittel
DE60006580D1 (de) Benzazolderivate und ihre verwendung als jnk modulatoren
ATE375987T1 (de) Arylmethyl-carbonylamino-thiazolderivate und ihre verwendung als antitumormittel
DE60031513D1 (de) Phenyl- und pyridinyl-derivate verwendbar als neurokinin-1-antagonisten
DE50110620D1 (de) Benzoylpyrazole und ihre verwendung als herbizide
DE60134338D1 (de) Piperazin-derivate
DK1847539T3 (da) Quinazolin-derivater
DE50112669D1 (de) Acridin-derivate und deren verwendung als arzneimittel
ATE329906T1 (de) Substituierte 2-anilino-benzimidazole und ihre verwendung als nhe-inhibitoren
DE602004010426D1 (de) Mikrobizide zusammensetzungen und ihre verwendung
DE60230162D1 (de) Polymerisate und ihre verwendung
DE60116732D1 (de) Isothiazol-derivate und ihre verwendung als schädlingsbekämpfungsmittel
DE60102151D1 (de) Neue thiochromanderivate und ihre verwendung als thrombininhibitoren
DE60141398D1 (de) Melphalan-derivate und ihre verwendung als chemotherapeutika gegen krebs
ATE506357T1 (de) Heterocyclische aminoalkylpyridinderivate als psychopharmaka

Legal Events

Date Code Title Description
8364 No opposition during term of opposition