SA112330950B1 - تركيبات غير ممرضة ناتجة من عودة الارتباط الجيني لفيروس مرض ماريك - Google Patents

تركيبات غير ممرضة ناتجة من عودة الارتباط الجيني لفيروس مرض ماريك Download PDF

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SA112330950B1
SA112330950B1 SA112330950A SA112330950A SA112330950B1 SA 112330950 B1 SA112330950 B1 SA 112330950B1 SA 112330950 A SA112330950 A SA 112330950A SA 112330950 A SA112330950 A SA 112330950A SA 112330950 B1 SA112330950 B1 SA 112330950B1
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Saudi Arabia
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virus
recombinant
vaccine
marek
iltv
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SA112330950A
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Arabic (ar)
English (en)
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جاكوبوس انتونيوس سونديرميجر باولوس
بيترسن جاري
كوك ستيفاني
مرسي محمد
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انترفيت انترناشونال بي في
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Application filed by انترفيت انترناشونال بي في filed Critical انترفيت انترناشونال بي في
Publication of SA112330950B1 publication Critical patent/SA112330950B1/ar

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/245—Herpetoviridae, e.g. herpes simplex virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5256—Virus expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
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    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16311—Mardivirus, e.g. Gallid herpesvirus 2, Marek-like viruses, turkey HV
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16311—Mardivirus, e.g. Gallid herpesvirus 2, Marek-like viruses, turkey HV
    • C12N2710/16321—Viruses as such, e.g. new isolates, mutants or their genomic sequences
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    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16311—Mardivirus, e.g. Gallid herpesvirus 2, Marek-like viruses, turkey HV
    • C12N2710/16334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16311—Mardivirus, e.g. Gallid herpesvirus 2, Marek-like viruses, turkey HV
    • C12N2710/16341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/16343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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    • C12N2720/10011—Birnaviridae
    • C—CHEMISTRY; METALLURGY
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    • C12N2720/10011—Birnaviridae
    • C12N2720/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
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    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
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    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18111—Avulavirus, e.g. Newcastle disease virus
    • C12N2760/18134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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  • Biochemistry (AREA)
  • Molecular Biology (AREA)
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  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
SA112330950A 2011-10-21 2012-10-21 تركيبات غير ممرضة ناتجة من عودة الارتباط الجيني لفيروس مرض ماريك SA112330950B1 (ar)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161549844P 2011-10-21 2011-10-21

Publications (1)

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SA112330950B1 true SA112330950B1 (ar) 2015-08-10

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SA112330950A SA112330950B1 (ar) 2011-10-21 2012-10-21 تركيبات غير ممرضة ناتجة من عودة الارتباط الجيني لفيروس مرض ماريك

Country Status (19)

Country Link
US (2) US8932604B2 (enExample)
EP (1) EP2768964B1 (enExample)
JP (2) JP6134324B2 (enExample)
CN (2) CN103890183A (enExample)
AR (1) AR088401A1 (enExample)
BR (1) BR112014009565A2 (enExample)
CA (3) CA2851658C (enExample)
ES (1) ES2700243T3 (enExample)
FR (1) FR21C1003I2 (enExample)
HU (2) HUE041723T2 (enExample)
IN (1) IN2014CN02681A (enExample)
MX (1) MX352206B (enExample)
MY (2) MY173856A (enExample)
PH (1) PH12014500793A1 (enExample)
PL (1) PL2768964T3 (enExample)
RU (1) RU2624037C2 (enExample)
SA (1) SA112330950B1 (enExample)
TR (1) TR201818883T4 (enExample)
WO (1) WO2013057236A1 (enExample)

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AR097029A1 (es) 2013-07-26 2016-02-17 Intervet Int Bv Aceleración de la respuesta inmune inducida por virus vectorial en aves, composición, uso, método para la vacunación y método para acelerar la respuesta inmune
EP2845904A1 (en) 2013-09-06 2015-03-11 Ceva Sante Animale Recombinant Marek's disease viruses and uses thereof
AR097762A1 (es) 2013-09-27 2016-04-13 Intervet Int Bv Formulaciones secas de vacunas que son estables a temperatura ambiente
US9950059B2 (en) 2014-02-25 2018-04-24 The United States Of America, As Represented By The Secretary Of Agriculture. Immunogenic composition
AR103245A1 (es) * 2014-12-24 2017-04-26 Intervet Int Bv Vacuna vectorial basada en hvt (herpes virus de los pavos) frente a nd (enfermedad de newcastle) - ibd (enfermedad de gumboro) mejorada
EP3050572A1 (en) * 2015-01-29 2016-08-03 Ceva Sante Animale Recombinant MDV1 and the uses thereof
EP3268034A4 (en) * 2015-03-05 2018-11-14 Northwestern University Non-neuroinvasive viruses and uses thereof
EP3334833A4 (en) 2015-08-10 2019-04-24 The Texas A&M University System RECOMBINANT TURKEY HERPESVIRUS VACCINES AND USES THEREOF
CN109310750B (zh) 2016-06-17 2022-08-12 英特维特国际股份有限公司 编码传染性喉气管炎病毒和传染性法氏囊病病毒抗原的重组非致病性马立克氏病病毒构建体
RU2752836C2 (ru) * 2016-12-14 2021-08-09 БЁРИНГЕР ИНГЕЛЬХАЙМ ЭНИМАЛ ХЕЛТ ЮЭсЭй ИНК. Рекомбинантные hvt-векторы, экспрессирующие множественные антигены патогенов птиц, и содержащие их вакцины
CN111542599A (zh) * 2017-10-12 2020-08-14 英特维特国际股份有限公司 编码多种异源抗原的重组非致病性马尔克氏病病毒构建体
CN107670032A (zh) * 2017-10-27 2018-02-09 贵州福斯特生物科技有限公司 家禽油乳剂灭活疫苗佐剂及其相应疫苗的制备方法
WO2019121888A1 (en) 2017-12-20 2019-06-27 Intervet International B.V. Improved diluent for cell-associated alphaherpesvirus vaccine
BR112021012032A2 (pt) 2018-12-21 2021-11-16 Ceva Sante Animale Herpesvírus aviários recombinantes contendo múltiplos genes estranhos
CN114616325A (zh) 2019-09-11 2022-06-10 硕腾服务有限责任公司 表达禽病原体抗原的重组火鸡疱疹病毒载体和其用途
WO2021123104A1 (en) 2019-12-20 2021-06-24 Intervet International B.V. Multivalent hvt vector vaccine
CN116457461A (zh) 2020-10-15 2023-07-18 法国诗华动物保健公司 重组hvt及其用途
MX2023007634A (es) 2020-12-24 2023-07-14 Intervet Int Bv Vacuna de vector hvt multivalente.
JP2025515050A (ja) 2022-05-05 2025-05-13 インターベット インターナショナル ベー． フェー． 新規多価ｈｖｔベクターワクチン
WO2025048868A1 (en) * 2023-08-30 2025-03-06 Edge Animal Health, Inc. Use of codon deoptimisation and optimisation to produce a laryngotracheitis virus-attenuated vaccine
TW202540431A (zh) * 2024-03-27 2025-10-16 大陸商勃林格殷格翰動物保健（中國）有限公司 重組血清1型馬立克氏病病毒

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