SA06260487B1 - تثبيط لأهداف فرط ضغط العين يتوسطه حمض ريبي نووي متداخل - Google Patents
تثبيط لأهداف فرط ضغط العين يتوسطه حمض ريبي نووي متداخل Download PDFInfo
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- SA06260487B1 SA06260487B1 SA6260487A SA06260487A SA06260487B1 SA 06260487 B1 SA06260487 B1 SA 06260487B1 SA 6260487 A SA6260487 A SA 6260487A SA 06260487 A SA06260487 A SA 06260487A SA 06260487 B1 SA06260487 B1 SA 06260487B1
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EP1856259A1 (de) | 2005-03-11 | 2007-11-21 | Alcon Inc. | Rnai-vermittelte hemmung von frizzled-verwandtem protein-1 zur behandlung von glaukomen |
GB0505081D0 (en) * | 2005-03-14 | 2005-04-20 | Genomica Sau | Downregulation of interleukin-12 expression by means of rnai technology |
GB0521351D0 (en) | 2005-10-20 | 2005-11-30 | Genomica Sau | Modulation of TRPV expression levels |
GB0521716D0 (en) | 2005-10-25 | 2005-11-30 | Genomica Sau | Modulation of 11beta-hydroxysteriod dehydrogenase 1 expression for the treatment of ocular diseases |
CA2634896C (en) * | 2005-12-30 | 2018-08-07 | Ventana Medical Systems, Inc. | Na+, k+-atpase expression in cervical dysplasia and cancer |
CN102743767A (zh) * | 2006-08-24 | 2012-10-24 | 爱尔康研究有限公司 | RNAi介导的Gremlin抑制用于治疗眼内压相关的状况 |
US20090054365A1 (en) * | 2007-01-26 | 2009-02-26 | Alcon Research, Ltd. | RNAi-MEDIATED INHIBITION OF AQUAPORIN 1 FOR TREATMENT OF OCULAR NEOVASCULARIZATION |
US20100292301A1 (en) * | 2007-02-28 | 2010-11-18 | Elena Feinstein | Novel sirna structures |
RU2010117178A (ru) * | 2007-10-01 | 2011-11-10 | Алькон Рисерч, Лтд. (Us) | Опосредованная самокомплементарными aav доставка молекул, интерферирующих рнк для лечения или профилактики глазных заболеваний |
US7973019B1 (en) | 2007-10-03 | 2011-07-05 | Alcon Research, Ltd. | Transferrin/transferrin receptor-mediated siRNA delivery |
EP2231168A4 (de) * | 2007-10-03 | 2012-01-04 | Quark Pharmaceuticals Inc | Neuartige sirna strukturen |
TW200930405A (en) * | 2007-11-15 | 2009-07-16 | Alcon Res Ltd | Low density lipoprotein receptor-mediated siRNA delivery |
AR069704A1 (es) | 2007-12-18 | 2010-02-10 | Alcon Res Ltd | Sistema de administracion de rnai de interferencia y usos del mismo |
EP2242854A4 (de) * | 2008-01-15 | 2012-08-15 | Quark Pharmaceuticals Inc | Sirna-verbindungen und verfahren zur verwendung davon |
NZ591391A (en) * | 2008-10-22 | 2012-10-26 | Quark Pharmaceuticals Inc | Non-invasive methods for treating eye disorders using a topical oligonucleotide composition |
WO2012161677A1 (en) | 2011-05-20 | 2012-11-29 | Alcon Research, Ltd. | TRANSFERRIN/TRANSFERRIN RECEPTOR-MEDIATED siRNA DELIVERY |
WO2013103467A1 (en) | 2012-01-06 | 2013-07-11 | Alcon Research, Ltd. | Interfering rna delivery system and uses thereof |
IN2015DN02699A (de) | 2012-09-05 | 2015-09-04 | Sylentis Sau | |
GB201215857D0 (en) | 2012-09-05 | 2012-10-24 | Sylentis Sau | siRNA and their use in methods and compositions for the treatment and/or prevention of eye conditions |
US10011837B2 (en) | 2014-03-04 | 2018-07-03 | Sylentis Sau | SiRNAs and their use in methods and compositions for the treatment and/or prevention of eye conditions |
EP3429567B1 (de) | 2016-03-16 | 2024-01-10 | The J. David Gladstone Institutes | Verfahren und zusammensetzungen zur behandlung von fettleibigkeit und/oder diabetes und zur identifizierung von behandlungskandidaten |
EP3388520A1 (de) * | 2017-04-11 | 2018-10-17 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Verfahren und pharmazeutische zusammensetzung zur reduzierung der expression von nkcc1 in einer darauf angewiesenen person |
CN109557309B (zh) * | 2018-12-04 | 2021-09-10 | 九江学院附属医院 | 碳酸酐酶-2作为检测标记物在肾结石诊断方面的应用 |
KR102414025B1 (ko) * | 2019-06-27 | 2022-06-29 | 전북대학교 산학협력단 | 신규한 에이디피-라이보실 사이클라아제 및 이의 저해제 |
KR20240014109A (ko) * | 2021-05-27 | 2024-01-31 | 알닐람 파마슈티칼스 인코포레이티드 | 탄산 무수화효소 2 발현을 침묵화하기 위한 조성물 및 방법 |
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US6506559B1 (en) * | 1997-12-23 | 2003-01-14 | Carnegie Institute Of Washington | Genetic inhibition by double-stranded RNA |
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2006
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- 2006-01-09 TW TW095100740A patent/TW200639253A/zh unknown
- 2006-01-20 AR ARP060100333A patent/AR052103A1/es not_active Application Discontinuation
- 2006-01-26 UY UY29349A patent/UY29349A1/es not_active Application Discontinuation
- 2006-01-26 UY UY29348A patent/UY29348A1/es not_active Application Discontinuation
- 2006-01-30 AR ARP060100332A patent/AR052102A1/es unknown
- 2006-01-30 SA SA6260487A patent/SA06260487B1/ar unknown
- 2006-02-01 KR KR1020077019714A patent/KR20070099048A/ko not_active Application Discontinuation
- 2006-02-01 EP EP06720051A patent/EP1846557A2/de not_active Withdrawn
- 2006-02-01 CA CA002595790A patent/CA2595790A1/en not_active Abandoned
- 2006-02-01 WO PCT/US2006/004018 patent/WO2006084217A2/en active Application Filing
- 2006-02-01 JP JP2007553390A patent/JP2008528637A/ja not_active Withdrawn
- 2006-02-01 KR KR1020077019895A patent/KR20070099673A/ko not_active Application Discontinuation
- 2006-02-01 EP EP06734380A patent/EP1848803A2/de not_active Ceased
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