RU94033484A - Способ получения производных имидазопиридина - Google Patents
Способ получения производных имидазопиридинаInfo
- Publication number
- RU94033484A RU94033484A RU94033484/04A RU94033484A RU94033484A RU 94033484 A RU94033484 A RU 94033484A RU 94033484/04 A RU94033484/04 A RU 94033484/04A RU 94033484 A RU94033484 A RU 94033484A RU 94033484 A RU94033484 A RU 94033484A
- Authority
- RU
- Russia
- Prior art keywords
- general formula
- aryl
- alkyl
- temperature
- hydrohalide
- Prior art date
Links
- 125000004857 imidazopyridinyl group Chemical class N1C(=NC2=C1C=CC=N2)* 0.000 title claims 2
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 claims abstract 9
- 150000001409 amidines Chemical class 0.000 claims abstract 3
- 125000000217 alkyl group Chemical group 0.000 claims 5
- 125000003710 aryl alkyl group Chemical group 0.000 claims 5
- 125000003118 aryl group Chemical group 0.000 claims 5
- 239000002585 base Substances 0.000 claims 3
- 238000007363 ring formation reaction Methods 0.000 claims 3
- 125000004453 alkoxycarbonyl group Chemical group 0.000 claims 2
- DFNYGALUNNFWKJ-UHFFFAOYSA-N aminoacetonitrile Chemical compound NCC#N DFNYGALUNNFWKJ-UHFFFAOYSA-N 0.000 claims 2
- 238000006243 chemical reaction Methods 0.000 claims 2
- 125000000753 cycloalkyl group Chemical group 0.000 claims 2
- 150000002431 hydrogen Chemical group 0.000 claims 2
- 229910052739 hydrogen Inorganic materials 0.000 claims 2
- 239000001257 hydrogen Substances 0.000 claims 2
- 239000012442 inert solvent Substances 0.000 claims 2
- 238000010992 reflux Methods 0.000 claims 2
- DNIAPMSPPWPWGF-GSVOUGTGSA-N (R)-(-)-Propylene glycol Chemical compound C[C@@H](O)CO DNIAPMSPPWPWGF-GSVOUGTGSA-N 0.000 claims 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims 1
- 229910052783 alkali metal Inorganic materials 0.000 claims 1
- 150000008044 alkali metal hydroxides Chemical class 0.000 claims 1
- 150000001340 alkali metals Chemical class 0.000 claims 1
- 125000003545 alkoxy group Chemical group 0.000 claims 1
- 150000008361 aminoacetonitriles Chemical class 0.000 claims 1
- 125000001589 carboacyl group Chemical group 0.000 claims 1
- 125000004093 cyano group Chemical group *C#N 0.000 claims 1
- 239000012467 final product Substances 0.000 claims 1
- 125000005843 halogen group Chemical group 0.000 claims 1
- 229910000041 hydrogen chloride Inorganic materials 0.000 claims 1
- IXCSERBJSXMMFS-UHFFFAOYSA-N hydrogen chloride Substances Cl.Cl IXCSERBJSXMMFS-UHFFFAOYSA-N 0.000 claims 1
- 229910000039 hydrogen halide Inorganic materials 0.000 claims 1
- 239000012433 hydrogen halide Substances 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- 150000007529 inorganic bases Chemical class 0.000 claims 1
- 150000002825 nitriles Chemical class 0.000 claims 1
- 150000007530 organic bases Chemical class 0.000 claims 1
- 239000002904 solvent Substances 0.000 claims 1
- 150000003573 thiols Chemical class 0.000 claims 1
- 230000009466 transformation Effects 0.000 claims 1
- 150000005232 imidazopyridines Chemical class 0.000 abstract 2
- 238000002360 preparation method Methods 0.000 abstract 2
- 239000005557 antagonist Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000013067 intermediate product Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH281593 | 1993-09-17 | ||
| CH2815/93 | 1993-09-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU94033484A true RU94033484A (ru) | 1996-08-10 |
Family
ID=48449057
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU94033484/04A RU94033484A (ru) | 1993-09-17 | 1994-09-16 | Способ получения производных имидазопиридина |
Country Status (3)
| Country | Link |
|---|---|
| KR (1) | KR950008511A (https=) |
| RU (1) | RU94033484A (https=) |
| TW (1) | TW306923B (https=) |
-
1994
- 1994-09-15 KR KR1019940023448A patent/KR950008511A/ko not_active Withdrawn
- 1994-09-16 RU RU94033484/04A patent/RU94033484A/ru unknown
- 1994-10-08 TW TW083109360A patent/TW306923B/zh active
Also Published As
| Publication number | Publication date |
|---|---|
| TW306923B (https=) | 1997-06-01 |
| KR950008511A (ko) | 1995-04-17 |
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