RU94022481A - Способ определения иммуногенной активности биоактивных соединений и состав для его осуществления - Google Patents
Способ определения иммуногенной активности биоактивных соединений и состав для его осуществленияInfo
- Publication number
- RU94022481A RU94022481A RU94022481/14A RU94022481A RU94022481A RU 94022481 A RU94022481 A RU 94022481A RU 94022481/14 A RU94022481/14 A RU 94022481/14A RU 94022481 A RU94022481 A RU 94022481A RU 94022481 A RU94022481 A RU 94022481A
- Authority
- RU
- Russia
- Prior art keywords
- estimation
- substance
- immunogenic activity
- realization
- cytokine production
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/02—Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
- A61K35/10—Peat; Amber; Turf; Humus
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
Иммунологическая активность определенных биоактивных веществ определяется обработкой культуры лейкоцитов периферической крови человека (РВL) или суспензии резидентных перитониальных клеток (RРС) мыши типа ВАLВ/с раствором тестируемого вещества для того, чтобы индуцировать продукцию цитокинов, которые определяются по стандартным способам идентификации, улучшение результатов может быть достигнуто при добавлении к тестируемому раствору нестероидного противовоспалительного лекарственного препарата, преимущественно индометацина. Способ также применим для определения иммунологической реакции индивидуумов человека на терапию с использованием веществ, индуцирующих цитокины.
Claims (1)
- Иммунологическая активность определенных биоактивных веществ определяется обработкой культуры лейкоцитов периферической крови человека (РВL) или суспензии резидентных перитониальных клеток (RРС) мыши типа ВАLВ/с раствором тестируемого вещества для того, чтобы индуцировать продукцию цитокинов, которые определяются по стандартным способам идентификации, улучшение результатов может быть достигнуто при добавлении к тестируемому раствору нестероидного противовоспалительного лекарственного препарата, преимущественно индометацина. Способ также применим для определения иммунологической реакции индивидуумов человека на терапию с использованием веществ, индуцирующих цитокины.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP91118269.9 | 1991-10-26 | ||
EP91118269A EP0539610A1 (en) | 1991-10-26 | 1991-10-26 | Method and composition for determining the immunological activity of solutions containing active substances |
Publications (2)
Publication Number | Publication Date |
---|---|
RU94022481A true RU94022481A (ru) | 1996-09-27 |
RU2125727C1 RU2125727C1 (ru) | 1999-01-27 |
Family
ID=8207282
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU94022481A RU2125727C1 (ru) | 1991-10-26 | 1992-09-28 | Способ определения иммуногенной активности биоактивных соединений и состав для его осуществления |
Country Status (23)
Country | Link |
---|---|
US (1) | US5543300A (ru) |
EP (2) | EP0539610A1 (ru) |
JP (1) | JPH07500905A (ru) |
AT (1) | ATE153763T1 (ru) |
AU (1) | AU678343B2 (ru) |
BG (1) | BG61705B1 (ru) |
CA (1) | CA2122131A1 (ru) |
CZ (1) | CZ100494A3 (ru) |
DE (3) | DE539610T1 (ru) |
DK (1) | DK0609255T3 (ru) |
ES (1) | ES2061424T3 (ru) |
FI (1) | FI941920A (ru) |
GR (3) | GR930300100T1 (ru) |
HK (1) | HK1002610A1 (ru) |
HU (1) | HU216863B (ru) |
LV (1) | LV12140B (ru) |
NO (1) | NO941444L (ru) |
PL (1) | PL170592B1 (ru) |
RO (1) | RO114837B1 (ru) |
RU (1) | RU2125727C1 (ru) |
SG (1) | SG72665A1 (ru) |
SK (1) | SK44094A3 (ru) |
WO (1) | WO1993008470A1 (ru) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19615470A1 (de) * | 1996-04-19 | 1997-10-23 | Heinz Beinio | Körperpflegemittel und Verfahren zu seiner Herstellung |
WO2000016785A2 (en) * | 1998-09-23 | 2000-03-30 | Enerkom (Proprietary) Limited | Humic acid and its use in the treatment of various conditions |
GB0101973D0 (en) * | 2001-01-25 | 2001-03-14 | Statens Seruminstitut | Improved in vitro diagnostic method of detecting a cell-mediated immune response |
DK1449535T3 (da) * | 2003-02-18 | 2006-09-11 | Clinique La Prairie Res Sa | Præparater der omfatter fötalt hæmoglobin og bakterieendotoksin samt eventuelt fötale leverbestanddele |
US7497947B2 (en) * | 2004-04-14 | 2009-03-03 | Embro Corporation | Devices for water treatment |
US7614340B2 (en) * | 2007-02-09 | 2009-11-10 | Honeywell International Inc. | Composite piston housing for aircraft brakes |
WO2013036601A1 (en) | 2011-09-07 | 2013-03-14 | Embro Corporation | Use of moss to reduce disinfection by-products in water treated with disinfectants |
US9795809B2 (en) | 2013-12-23 | 2017-10-24 | Embro Corporation | Use of moss to improve dental health |
US10058542B1 (en) | 2014-09-12 | 2018-08-28 | Thioredoxin Systems Ab | Composition comprising selenazol or thiazolone derivatives and silver and method of treatment therewith |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH636448A5 (en) * | 1977-05-06 | 1983-05-31 | Horst Veith | Process for the determination of the effect of substances on constituents of the blood for the detection of infectious and immunological processes and composition for carrying it out |
NZ214400A (en) * | 1985-12-02 | 1989-05-29 | Univ Otago | Detecting infection in ruminant including conducting assay of mononuclear cell function |
EP0238851B1 (en) * | 1986-02-19 | 1992-12-09 | Imreg, Inc. | A method and means of assaying an immune system |
AU595021B2 (en) * | 1986-03-06 | 1990-03-22 | Commonwealth Scientific And Industrial Research Organisation | In vitro assay for detecting cell-mediated immune responses |
US5096708A (en) * | 1988-07-07 | 1992-03-17 | Sven Gohla | Medical preparation containing as active agent a component from thuja plants which comprises polysaccharides |
DK0529032T3 (da) * | 1991-03-16 | 1996-04-09 | Torf Ets | Fremgangsmåde til ekstraktion af tørv og apparat til udførelse af fremgangsmåden |
-
1991
- 1991-10-26 DE DE91118269T patent/DE539610T1/de active Pending
- 1991-10-26 EP EP91118269A patent/EP0539610A1/en not_active Withdrawn
-
1992
- 1992-09-28 RO RO94-00711A patent/RO114837B1/ro unknown
- 1992-09-28 JP JP5507380A patent/JPH07500905A/ja active Pending
- 1992-09-28 DE DE69220078T patent/DE69220078T2/de not_active Expired - Fee Related
- 1992-09-28 AT AT92920622T patent/ATE153763T1/de not_active IP Right Cessation
- 1992-09-28 SG SG1996007958A patent/SG72665A1/en unknown
- 1992-09-28 AU AU26509/92A patent/AU678343B2/en not_active Ceased
- 1992-09-28 DE DE0609255T patent/DE609255T1/de active Pending
- 1992-09-28 WO PCT/EP1992/002228 patent/WO1993008470A1/en not_active Application Discontinuation
- 1992-09-28 HU HU9401185A patent/HU216863B/hu not_active IP Right Cessation
- 1992-09-28 SK SK440-94A patent/SK44094A3/sk unknown
- 1992-09-28 EP EP92920622A patent/EP0609255B1/en not_active Expired - Lifetime
- 1992-09-28 CZ CZ941004A patent/CZ100494A3/cs unknown
- 1992-09-28 CA CA002122131A patent/CA2122131A1/en not_active Abandoned
- 1992-09-28 ES ES92920622T patent/ES2061424T3/es not_active Expired - Lifetime
- 1992-09-28 RU RU94022481A patent/RU2125727C1/ru active
- 1992-09-28 DK DK92920622.5T patent/DK0609255T3/da active
- 1992-09-28 PL PL92303417A patent/PL170592B1/pl unknown
- 1992-09-28 US US08/211,909 patent/US5543300A/en not_active Expired - Fee Related
-
1993
- 1993-10-29 GR GR930300100T patent/GR930300100T1/el unknown
-
1994
- 1994-04-14 BG BG98720A patent/BG61705B1/bg unknown
- 1994-04-21 NO NO941444A patent/NO941444L/no not_active Application Discontinuation
- 1994-04-25 FI FI941920A patent/FI941920A/fi unknown
- 1994-11-30 GR GR940300077T patent/GR940300077T1/el unknown
-
1997
- 1997-08-14 GR GR970402095T patent/GR3024457T3/el unknown
-
1998
- 1998-03-03 HK HK98101626A patent/HK1002610A1/xx not_active IP Right Cessation
- 1998-05-28 LV LVP-98-125A patent/LV12140B/lv unknown
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