RU2763319C2 - Реагенты для лечения окулофарингеальной мышечной дистрофии (офмд) и их применение - Google Patents

Реагенты для лечения окулофарингеальной мышечной дистрофии (офмд) и их применение Download PDF

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RU2763319C2
RU2763319C2 RU2019121950A RU2019121950A RU2763319C2 RU 2763319 C2 RU2763319 C2 RU 2763319C2 RU 2019121950 A RU2019121950 A RU 2019121950A RU 2019121950 A RU2019121950 A RU 2019121950A RU 2763319 C2 RU2763319 C2 RU 2763319C2
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sequence
effector
nucleic acid
lncrnai
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RU2019121950A
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RU2019121950A (ru
RU2019121950A3 (enExample
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Ванесса СТРИНГЗ-УФОМБАХ
Дэвид СЬЮХИ
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Бенитек АйПи Холдингз Инк.
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RU2019121950A 2016-12-14 2017-12-14 Реагенты для лечения окулофарингеальной мышечной дистрофии (офмд) и их применение RU2763319C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662434312P 2016-12-14 2016-12-14
US62/434,312 2016-12-14
PCT/AU2017/051385 WO2018107228A1 (en) 2016-12-14 2017-12-14 Reagents for treatment of oculopharyngeal muscular dystrophy (opmd) and use thereof

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RU2019121950A RU2019121950A (ru) 2021-01-18
RU2019121950A3 RU2019121950A3 (enExample) 2021-01-18
RU2763319C2 true RU2763319C2 (ru) 2021-12-28

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US (2) US11142765B2 (enExample)
EP (1) EP3555294A4 (enExample)
JP (2) JP7233149B2 (enExample)
KR (2) KR102667867B1 (enExample)
CN (2) CN118421624A (enExample)
AU (2) AU2017377661B2 (enExample)
BR (1) BR112019012312A8 (enExample)
CA (1) CA3047154A1 (enExample)
IL (2) IL304674B2 (enExample)
MX (2) MX2019007110A (enExample)
RU (1) RU2763319C2 (enExample)
WO (1) WO2018107228A1 (enExample)
ZA (1) ZA202106827B (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11142765B2 (en) * 2016-12-14 2021-10-12 Benitec Ip Holdings, Inc. Reagents for treatment of oculopharyngeal muscular dystrophy (OPMD) and use thereof
CA3114945A1 (en) * 2018-10-17 2020-04-23 Benitec Biopharma Limited Methods for treating oculopharyngeal muscular dystrophy (opmd)
EP3931317A4 (en) 2019-02-28 2023-01-04 Benitec IP Holdings Inc. COMPOSITIONS AND METHODS FOR TREATMENT OF OCULOPHARYNGEAL MUSCULAR DYSTROPHY (OPMD)
IL294132A (en) * 2019-12-23 2022-08-01 Versameb Ag Compositions and methods for simultaneously modulating expression of genes

Citations (2)

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WO2008150897A2 (en) * 2007-05-31 2008-12-11 University Of Iowa Research Foundation Reduction of off-target rna interference toxicity
RU2659423C2 (ru) * 2012-02-16 2018-07-02 ЭйТИР ФАРМА, ИНК. ГИСТИДИЛ-тРНК-СИНТЕТАЗЫ ДЛЯ ЛЕЧЕНИЯ АУТОИММУННЫХ И ВОСПАЛИТЕЛЬНЫХ ЗАБОЛЕВАНИЙ

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ES2566561T3 (es) * 2001-07-12 2016-04-13 University Of Massachusetts Producción in vivo de ARN pequeños de interferencia que median el silenciamiento génico
EP1783645A1 (en) * 2005-11-08 2007-05-09 Actigenics Methods for the identification of microRNA and their applications in research and human health
BRPI0807047A2 (pt) * 2007-01-31 2014-04-22 Basf Plant Science Gmbh Método para o aumento da resistência ao estresse abiótico em plantas relativa as plantas de controle, e, usos de uma construção, e de um ácido nucleico que codifica um polipeptídeo semelhante a nap1.
WO2010105372A1 (en) * 2009-03-20 2010-09-23 Protiva Biotherapeutics, Inc. Compositions and methods for silencing hepatitis c virus expression
WO2014077693A1 (en) * 2012-11-16 2014-05-22 Academisch Ziekenhuis Leiden H.O.D.N. Lumc Means and methods for reducing an effect of aging in a mammalian cell
AU2014205036A1 (en) * 2013-01-08 2015-07-30 Benitec Biopharma Limited Age-related macular degeneration treatment
KR102353847B1 (ko) 2016-04-14 2022-01-21 베니텍 바이오파마 리미티드 안구인두 근이영양증(opmd)의 치료용 시약 및 이의 용도
US11142765B2 (en) 2016-12-14 2021-10-12 Benitec Ip Holdings, Inc. Reagents for treatment of oculopharyngeal muscular dystrophy (OPMD) and use thereof

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WO2008150897A2 (en) * 2007-05-31 2008-12-11 University Of Iowa Research Foundation Reduction of off-target rna interference toxicity
RU2659423C2 (ru) * 2012-02-16 2018-07-02 ЭйТИР ФАРМА, ИНК. ГИСТИДИЛ-тРНК-СИНТЕТАЗЫ ДЛЯ ЛЕЧЕНИЯ АУТОИММУННЫХ И ВОСПАЛИТЕЛЬНЫХ ЗАБОЛЕВАНИЙ

Non-Patent Citations (3)

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Title
ANVAR, S.Y. et al., "A decline in PABPN1 induces progressive muscle weakness in Oculopharyngeal muscle dystrophy and in muscle again", Aging, vol. 5, no. 6, (20130601), pages 412 - 426. *
M. RIAZ et al. "PABPN1-Dependent mRNA Processing Induces Muscle Wasting". PLoS Genet 12(5): e1006031. *
M. RIAZ et al. "PABPN1-Dependent mRNA Processing Induces Muscle Wasting". PLoS Genet 12(5): e1006031. ANVAR, S.Y. et al., "A decline in PABPN1 induces progressive muscle weakness in Oculopharyngeal muscle dystrophy and in muscle again", Aging, vol. 5, no. 6, (20130601), pages 412 - 426. *

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BR112019012312A2 (pt) 2020-02-11
AU2017377661A1 (en) 2019-07-18
KR20190104151A (ko) 2019-09-06
JP7233149B2 (ja) 2023-03-06
MX2019007110A (es) 2019-12-05
MX2024003643A (es) 2024-04-15
KR102495222B1 (ko) 2023-02-09
CN118421624A (zh) 2024-08-02
US11142765B2 (en) 2021-10-12
IL304674B2 (en) 2024-11-01
IL267353A (en) 2019-08-29
US11932852B2 (en) 2024-03-19
WO2018107228A1 (en) 2018-06-21
CN110382698B (zh) 2024-05-10
AU2023222827A1 (en) 2023-09-14
JP2020503014A (ja) 2020-01-30
IL304674A (en) 2023-09-01
CN110382698A (zh) 2019-10-25
JP2023062092A (ja) 2023-05-02
IL304674B1 (en) 2024-07-01
EP3555294A4 (en) 2020-08-26
CA3047154A1 (en) 2018-06-21
RU2019121950A (ru) 2021-01-18
EP3555294A1 (en) 2019-10-23
AU2023222827B2 (en) 2025-02-27
IL267353B2 (en) 2023-12-01
KR20230020586A (ko) 2023-02-10
AU2017377661B2 (en) 2023-07-27
IL267353B1 (en) 2023-08-01
ZA202106827B (en) 2022-07-27
KR102667867B1 (ko) 2024-05-29
RU2019121950A3 (enExample) 2021-01-18
JP7431359B2 (ja) 2024-02-14
BR112019012312A8 (pt) 2023-02-28
US20220056446A1 (en) 2022-02-24
US20190330629A1 (en) 2019-10-31

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