IL304674B2 - Reagents for treating Oculopharyngeal Muscular Dystrophy (OPMD) and their uses - Google Patents
Reagents for treating Oculopharyngeal Muscular Dystrophy (OPMD) and their usesInfo
- Publication number
- IL304674B2 IL304674B2 IL304674A IL30467423A IL304674B2 IL 304674 B2 IL304674 B2 IL 304674B2 IL 304674 A IL304674 A IL 304674A IL 30467423 A IL30467423 A IL 30467423A IL 304674 B2 IL304674 B2 IL 304674B2
- Authority
- IL
- Israel
- Prior art keywords
- seq
- set forth
- nucleic acid
- shmir
- effector
- Prior art date
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- C12N2740/10043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
- C12N2740/15041—Use of virus, viral particle or viral elements as a vector
- C12N2740/15043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14141—Use of virus, viral particle or viral elements as a vector
- C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2800/00—Nucleic acids vectors
- C12N2800/22—Vectors comprising a coding region that has been codon optimised for expression in a respective host
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/008—Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662434312P | 2016-12-14 | 2016-12-14 | |
| PCT/AU2017/051385 WO2018107228A1 (en) | 2016-12-14 | 2017-12-14 | Reagents for treatment of oculopharyngeal muscular dystrophy (opmd) and use thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| IL304674A IL304674A (en) | 2023-09-01 |
| IL304674B1 IL304674B1 (en) | 2024-07-01 |
| IL304674B2 true IL304674B2 (en) | 2024-11-01 |
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL304674A IL304674B2 (en) | 2016-12-14 | 2017-12-14 | Reagents for treating Oculopharyngeal Muscular Dystrophy (OPMD) and their uses |
| IL267353A IL267353B2 (en) | 2016-12-14 | 2017-12-14 | Reagents for the treatment of (OCULOPHARYNGEAL MUSCULAR DYSTROPHY (OPMD) and their uses |
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| Application Number | Title | Priority Date | Filing Date |
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| IL267353A IL267353B2 (en) | 2016-12-14 | 2017-12-14 | Reagents for the treatment of (OCULOPHARYNGEAL MUSCULAR DYSTROPHY (OPMD) and their uses |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US11142765B2 (enExample) |
| EP (1) | EP3555294A4 (enExample) |
| JP (2) | JP7233149B2 (enExample) |
| KR (2) | KR102667867B1 (enExample) |
| CN (2) | CN118421624A (enExample) |
| AU (2) | AU2017377661B2 (enExample) |
| BR (1) | BR112019012312A8 (enExample) |
| CA (1) | CA3047154A1 (enExample) |
| IL (2) | IL304674B2 (enExample) |
| MX (2) | MX2019007110A (enExample) |
| RU (1) | RU2763319C2 (enExample) |
| WO (1) | WO2018107228A1 (enExample) |
| ZA (1) | ZA202106827B (enExample) |
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| US11142765B2 (en) * | 2016-12-14 | 2021-10-12 | Benitec Ip Holdings, Inc. | Reagents for treatment of oculopharyngeal muscular dystrophy (OPMD) and use thereof |
| CA3114945A1 (en) * | 2018-10-17 | 2020-04-23 | Benitec Biopharma Limited | Methods for treating oculopharyngeal muscular dystrophy (opmd) |
| EP3931317A4 (en) | 2019-02-28 | 2023-01-04 | Benitec IP Holdings Inc. | COMPOSITIONS AND METHODS FOR TREATMENT OF OCULOPHARYNGEAL MUSCULAR DYSTROPHY (OPMD) |
| IL294132A (en) * | 2019-12-23 | 2022-08-01 | Versameb Ag | Compositions and methods for simultaneously modulating expression of genes |
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| ES2566561T3 (es) * | 2001-07-12 | 2016-04-13 | University Of Massachusetts | Producción in vivo de ARN pequeños de interferencia que median el silenciamiento génico |
| EP1783645A1 (en) * | 2005-11-08 | 2007-05-09 | Actigenics | Methods for the identification of microRNA and their applications in research and human health |
| BRPI0807047A2 (pt) * | 2007-01-31 | 2014-04-22 | Basf Plant Science Gmbh | Método para o aumento da resistência ao estresse abiótico em plantas relativa as plantas de controle, e, usos de uma construção, e de um ácido nucleico que codifica um polipeptídeo semelhante a nap1. |
| PT2164967E (pt) * | 2007-05-31 | 2015-10-27 | Univ Iowa Res Found | Redução da toxicidade não dirigida do arn de interferência |
| WO2010105372A1 (en) * | 2009-03-20 | 2010-09-23 | Protiva Biotherapeutics, Inc. | Compositions and methods for silencing hepatitis c virus expression |
| JP6170077B2 (ja) * | 2012-02-16 | 2017-07-26 | エータイアー ファーマ， インコーポレイテッド | 自己免疫および炎症疾患を処置するためのヒスチジルｔＲＮＡ合成酵素 |
| WO2014077693A1 (en) * | 2012-11-16 | 2014-05-22 | Academisch Ziekenhuis Leiden H.O.D.N. Lumc | Means and methods for reducing an effect of aging in a mammalian cell |
| AU2014205036A1 (en) * | 2013-01-08 | 2015-07-30 | Benitec Biopharma Limited | Age-related macular degeneration treatment |
| KR102353847B1 (ko) | 2016-04-14 | 2022-01-21 | 베니텍 바이오파마 리미티드 | 안구인두 근이영양증(opmd)의 치료용 시약 및 이의 용도 |
| US11142765B2 (en) | 2016-12-14 | 2021-10-12 | Benitec Ip Holdings, Inc. | Reagents for treatment of oculopharyngeal muscular dystrophy (OPMD) and use thereof |
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2017
- 2017-12-14 US US16/469,992 patent/US11142765B2/en active Active
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- 2017-12-14 IL IL267353A patent/IL267353B2/en unknown
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- 2017-12-14 WO PCT/AU2017/051385 patent/WO2018107228A1/en not_active Ceased
- 2017-12-14 KR KR1020237003441A patent/KR102667867B1/ko active Active
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- 2017-12-14 MX MX2019007110A patent/MX2019007110A/es unknown
- 2017-12-14 AU AU2017377661A patent/AU2017377661B2/en active Active
- 2017-12-14 CN CN202410482087.4A patent/CN118421624A/zh active Pending
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- 2017-12-14 BR BR112019012312A patent/BR112019012312A8/pt active Search and Examination
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2019
- 2019-06-14 MX MX2024003643A patent/MX2024003643A/es unknown
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2021
- 2021-09-01 US US17/463,923 patent/US11932852B2/en active Active
- 2021-09-17 ZA ZA2021/06827A patent/ZA202106827B/en unknown
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2023
- 2023-02-17 JP JP2023023159A patent/JP7431359B2/ja active Active
- 2023-08-28 AU AU2023222827A patent/AU2023222827B2/en active Active
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