RU2746413C1 - Антитело, специфически связывающееся с muc1, и его применение - Google Patents

Антитело, специфически связывающееся с muc1, и его применение Download PDF

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RU2746413C1
RU2746413C1 RU2019132900A RU2019132900A RU2746413C1 RU 2746413 C1 RU2746413 C1 RU 2746413C1 RU 2019132900 A RU2019132900 A RU 2019132900A RU 2019132900 A RU2019132900 A RU 2019132900A RU 2746413 C1 RU2746413 C1 RU 2746413C1
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antibody
muc1
cancer
antigen
cells
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RU2019132900A
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English (en)
Russian (ru)
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Кюн Тюк МУН
Хо Ил ЦОЙ
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Пептрон, Инк.
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Priority claimed from PCT/KR2018/003267 external-priority patent/WO2018174544A2/ko
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07K16/3076—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties
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    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
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    • G—PHYSICS
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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RU2019132900A 2017-03-21 2018-03-21 Антитело, специфически связывающееся с muc1, и его применение RU2746413C1 (ru)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
KR10-2017-0035622 2017-03-21
KR20170035622 2017-03-21
KR10-2018-0032592 2018-03-21
PCT/KR2018/003267 WO2018174544A2 (ko) 2017-03-21 2018-03-21 Muc1에 특이적으로 결합하는 항체 및 그의 용도
KR1020180032592A KR102127421B1 (ko) 2017-03-21 2018-03-21 Muc1에 특이적으로 결합하는 항체 및 그의 용도

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RU2746413C1 true RU2746413C1 (ru) 2021-04-13

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US (4) US11472887B2 (enExample)
EP (2) EP3825328A1 (enExample)
JP (3) JP7032425B2 (enExample)
KR (2) KR102127421B1 (enExample)
CN (1) CN111201240B (enExample)
AU (3) AU2018238165C1 (enExample)
BR (1) BR112019019650A2 (enExample)
CA (1) CA3056582C (enExample)
IL (1) IL269488B2 (enExample)
MX (1) MX2019011101A (enExample)
RU (1) RU2746413C1 (enExample)
ZA (1) ZA201906813B (enExample)

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* Cited by examiner, † Cited by third party
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CA3056582C (en) 2017-03-21 2022-05-31 Peptron, Inc. Antibody binding specifically to muc1 and use thereof
EP3983447A4 (en) 2019-06-14 2023-06-28 Dana-Farber Cancer Institute, Inc. Antibodies against muc1 and methods of use thereof
IL296572A (en) * 2020-03-18 2022-11-01 Biomodifying Llc Anti- muc1-sea antibodies
KR102811084B1 (ko) * 2020-12-24 2025-05-23 주식회사 엘지화학 뮤신 1에 특이적인 폴리펩티드 및 이의 이용
KR20240040098A (ko) * 2021-07-30 2024-03-27 알.피.쉐러 테크놀러지즈 엘엘씨 넥틴-4에 특이적인 항체 및 항체 접합체 및 이의 사용방법
AU2022333837A1 (en) 2021-08-27 2024-03-14 Peptron, Inc. Novel anti-muc1 antibody and use thereof
CN114028539B (zh) * 2021-09-13 2024-04-26 北京大学 粘蛋白1在抑制冠状病毒中的应用
CN114106110B (zh) * 2021-11-25 2025-04-18 国家纳米科学中心 一种特异性结合muc1蛋白的多肽、靶向载药共递送系统及其制备方法与应用
EP4471066A4 (en) * 2022-01-24 2025-10-01 Cyron Therapeutics Co Ltd ANTIBODIES SPECIFICALLY BINDING TO MUC-1 AND USES THEREOF
CN116554317B (zh) * 2022-01-29 2025-02-28 浙江纳米抗体技术中心有限公司 Muc1结合分子及其应用
WO2023201234A2 (en) 2022-04-12 2023-10-19 Minerva Biotechnologies Corporation Anti-variable muc1* antibodies and uses thereof
AU2024207058A1 (en) * 2023-01-09 2025-06-26 Biocytogen Pharmaceuticals (Beijing) Co., Ltd. Anti-egfr/muc1 antibodies and uses thereof
TW202436357A (zh) * 2023-03-03 2024-09-16 瑞士商百濟神州瑞士有限責任公司 Ｍｕｃ１抗體及使用方法
CN120813609A (zh) * 2023-03-03 2025-10-17 广州百济神州生物制药有限公司 Muc1和cd16a抗体及使用方法
WO2024213106A1 (zh) * 2023-04-13 2024-10-17 江苏恒瑞医药股份有限公司 特异性结合egfr和muc1的抗原结合分子、其药物偶联物及其医药用途
WO2025026358A1 (zh) * 2023-08-01 2025-02-06 浙江纳米抗体技术中心有限公司 Muc1结合分子和包含其的嵌合抗原受体
US20250121088A1 (en) * 2023-10-11 2025-04-17 Minerva Biotechnologies Corporation Anti-muc1* antibody drug complexes and uses thereof
WO2025218621A1 (zh) * 2024-04-15 2025-10-23 原启生物科技(上海)有限责任公司 靶向muc1的抗原结合蛋白

Citations (4)

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