RU2722451C1 - Pd-1 антитела и их применение. - Google Patents
Pd-1 антитела и их применение. Download PDFInfo
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- RU2722451C1 RU2722451C1 RU2018115575A RU2018115575A RU2722451C1 RU 2722451 C1 RU2722451 C1 RU 2722451C1 RU 2018115575 A RU2018115575 A RU 2018115575A RU 2018115575 A RU2018115575 A RU 2018115575A RU 2722451 C1 RU2722451 C1 RU 2722451C1
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- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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| US201562234076P | 2015-09-29 | 2015-09-29 | |
| US62/234,076 | 2015-09-29 | ||
| PCT/SG2016/050482 WO2017058115A1 (en) | 2015-09-29 | 2016-09-29 | Pd-1 antibodies and uses thereof |
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| RU (1) | RU2722451C1 (de) |
| WO (1) | WO2017058115A1 (de) |
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| KR20180040138A (ko) | 2015-07-13 | 2018-04-19 | 싸이톰스 테라퓨틱스, 인크. | 항pd-1 항체, 활성화 가능한 항pd-1 항체, 및 이들의 사용 방법 |
| EA201890630A1 (ru) | 2015-09-01 | 2018-10-31 | Эйдженус Инк. | Антитела против pd-1 и способы их применения |
| BR112018006237A2 (pt) | 2015-09-29 | 2018-10-09 | Celgene Corp | proteínas de ligação a pd-1 e métodos de uso das mesmas |
| PL3370768T3 (pl) | 2015-11-03 | 2022-06-13 | Janssen Biotech, Inc. | Przeciwciała specyficznie wiążące pd-1 i ich zastosowania |
| JP7261379B2 (ja) | 2016-06-20 | 2023-04-20 | カイマブ・リミテッド | 抗ｐｄ－ｌ１抗体 |
| US10751414B2 (en) | 2016-09-19 | 2020-08-25 | Celgene Corporation | Methods of treating psoriasis using PD-1 binding antibodies |
| EP3515943A4 (de) | 2016-09-19 | 2020-05-06 | Celgene Corporation | Verfahren zur behandlung von vitiligo mithilfe von pd-1-bindenden proteinen |
| CN110300599A (zh) | 2016-12-07 | 2019-10-01 | 艾吉纳斯公司 | 抗体和其使用方法 |
| TWI771361B (zh) | 2017-01-20 | 2022-07-21 | 大陸商大有華夏生物醫藥集團有限公司 | 人程序性死亡受體pd-1的單株抗體及其片段 |
| CN108341871A (zh) * | 2017-01-24 | 2018-07-31 | 三生国健药业（上海）股份有限公司 | 抗pd-1单克隆抗体及其制备方法和应用 |
| WO2019106592A2 (en) | 2017-11-30 | 2019-06-06 | Grifols Diagnostic Solutions Inc. | Immunoassays and engineered proteins for monitoring antibody treatments to the immune checkpoint inhibitors pd1 and pd-l1 |
| KR102608723B1 (ko) | 2018-02-23 | 2023-12-01 | 유큐(베이징) 바이오파마 코., 엘티디 | 항―ｐｄ－１ 항체 및 그의 용도 |
| CN112074533A (zh) * | 2018-04-15 | 2020-12-11 | 信立泰(成都)生物技术有限公司 | 结合pd-1的抗体及其用途 |
| CN112074297B (zh) * | 2018-04-15 | 2023-11-14 | 深圳市亦诺微医药科技有限公司 | 结合pd-1的抗体及其用途 |
| EA202190181A1 (ru) * | 2018-07-04 | 2021-05-27 | Сайтоиммьюн Терапьютикс, Инк. | Композиции и способы для направленной иммунотерапии flt3, pd-1 и/или pd-l1 |
| JP2021530511A (ja) * | 2018-07-19 | 2021-11-11 | タユー ファシャ バイオテック メディカル グループ カンパニー， リミテッド | 抗ｐｄ−１抗体、投薬量、およびその使用 |
| AU2019382505A1 (en) * | 2018-11-19 | 2021-05-27 | Biocytogen Pharmaceuticals (Beijing) Co., Ltd. | Anti-PD-1 antibodies and uses thereof |
| CN111423510B (zh) * | 2019-01-10 | 2024-02-06 | 迈威(上海)生物科技股份有限公司 | 重组抗人pd-1抗体及其应用 |
| TWI809286B (zh) | 2019-07-05 | 2023-07-21 | 日商小野藥品工業股份有限公司 | 以pd-1/cd3雙特異性蛋白質所進行之血液性癌症治療 |
| JPWO2021025140A1 (de) | 2019-08-08 | 2021-02-11 | ||
| EP4039704A4 (de) * | 2019-09-30 | 2023-09-20 | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. | Anti-pd-1-antikörper und verwendung davon |
| KR20230163503A (ko) * | 2021-03-31 | 2023-11-30 | 메뤼스 엔.페. | 신규한 pd-1 결합 도메인 |
| GB202107994D0 (en) | 2021-06-04 | 2021-07-21 | Kymab Ltd | Treatment of cancer |
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| WO2006121168A1 (en) * | 2005-05-09 | 2006-11-16 | Ono Pharmaceutical Co., Ltd. | Human monoclonal antibodies to programmed death 1(pd-1) and methods for treating cancer using anti-pd-1 antibodies alone or in combination with other immunotherapeutics |
| WO2014008218A1 (en) * | 2012-07-02 | 2014-01-09 | Bristol-Myers Squibb Company | Optimization of antibodies that bind lymphocyte activation gene-3 (lag-3), and uses thereof |
| RU2515904C2 (ru) * | 2006-09-28 | 2014-05-20 | Пьер Фабр Медикамент | Способ генерирования активных антител к антигену устойчивости, антитела, полученные этим способом, и их применения |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| PT2206517T (pt) * | 2002-07-03 | 2023-11-07 | Tasuku Honjo | Composições de imunopotenciação contendo anticorpos anti-pd-l1 |
| RS53072B (en) * | 2007-06-18 | 2014-04-30 | Merck Sharp & Dohme B.V. | HUMAN RECEPTOR ANTIBODIES PROGRAMMED DEATH PD-1 |
| TW201134488A (en) * | 2010-03-11 | 2011-10-16 | Ucb Pharma Sa | PD-1 antibodies |
| CN105339389B (zh) * | 2013-05-02 | 2021-04-27 | 安奈普泰斯生物有限公司 | 针对程序性死亡-1(pd-1)的抗体 |
| CA3175360C (en) * | 2013-05-31 | 2024-05-28 | Sorrento Therapeutics, Inc. | Antigen binding proteins that bind pd-1 |
| CN104250302B (zh) | 2013-06-26 | 2017-11-14 | 上海君实生物医药科技股份有限公司 | 抗pd‑1抗体及其应用 |
| JP6623353B2 (ja) * | 2013-09-13 | 2019-12-25 | ベイジーン スウィッツァーランド ゲーエムベーハー | 抗ｐｄ−１抗体並びにその治療及び診断のための使用 |
| CN105026428B (zh) * | 2013-12-12 | 2018-01-16 | 上海恒瑞医药有限公司 | PD‑l抗体、其抗原结合片段及其医药用途 |
| TWI681969B (zh) * | 2014-01-23 | 2020-01-11 | 美商再生元醫藥公司 | 針對ｐｄ-１的人類抗體 |
| JOP20200094A1 (ar) | 2014-01-24 | 2017-06-16 | Dana Farber Cancer Inst Inc | جزيئات جسم مضاد لـ pd-1 واستخداماتها |
-
2016
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- 2016-09-29 US US15/764,494 patent/US10981991B2/en active Active
- 2016-09-29 CN CN201680069571.8A patent/CN108368175B/zh active Active
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- 2016-09-29 KR KR1020187012011A patent/KR20180083318A/ko not_active Application Discontinuation
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| WO2006121168A1 (en) * | 2005-05-09 | 2006-11-16 | Ono Pharmaceutical Co., Ltd. | Human monoclonal antibodies to programmed death 1(pd-1) and methods for treating cancer using anti-pd-1 antibodies alone or in combination with other immunotherapeutics |
| RU2515904C2 (ru) * | 2006-09-28 | 2014-05-20 | Пьер Фабр Медикамент | Способ генерирования активных антител к антигену устойчивости, антитела, полученные этим способом, и их применения |
| WO2014008218A1 (en) * | 2012-07-02 | 2014-01-09 | Bristol-Myers Squibb Company | Optimization of antibodies that bind lymphocyte activation gene-3 (lag-3), and uses thereof |
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| Publication number | Publication date |
|---|---|
| WO2017058115A1 (en) | 2017-04-06 |
| CA3000638A1 (en) | 2017-04-06 |
| CN108368175B (zh) | 2021-08-06 |
| CA3000638C (en) | 2024-02-27 |
| KR20180083318A (ko) | 2018-07-20 |
| EP3356416A1 (de) | 2018-08-08 |
| EP3356416A4 (de) | 2019-04-10 |
| CN108368175A (zh) | 2018-08-03 |
| BR112018006547A2 (pt) | 2018-12-11 |
| JP6952028B2 (ja) | 2021-10-20 |
| JP2018529368A (ja) | 2018-10-11 |
| US10981991B2 (en) | 2021-04-20 |
| US20180282412A1 (en) | 2018-10-04 |
| EP3356416B1 (de) | 2021-03-24 |
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