RU2700083C2 - Применение генетически модифицированного патогенного вируса кори с улучшенными проапоптотическими свойствами (вирус mv-deltac) в терапии рака - Google Patents

Применение генетически модифицированного патогенного вируса кори с улучшенными проапоптотическими свойствами (вирус mv-deltac) в терапии рака Download PDF

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RU2700083C2
RU2700083C2 RU2015128913A RU2015128913A RU2700083C2 RU 2700083 C2 RU2700083 C2 RU 2700083C2 RU 2015128913 A RU2015128913 A RU 2015128913A RU 2015128913 A RU2015128913 A RU 2015128913A RU 2700083 C2 RU2700083 C2 RU 2700083C2
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cells
cancer
deltac
tumor
measles virus
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RU2015128913A
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RU2015128913A (ru
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Фредерик ТАНЖИ
Марк ГРЕГОРИ
Жан-Франсуа ФОНТЕНЮ
Жан-Баптист ЖУЛЛЕРМЕ
Шанталь КОМБРЕДЕ
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Институт Пастер
Сентре Натионал Де Ла Решерше Сиентифик
Энститю Насьональ Де Ля Сантэ Э Де Ля Решерш Медикаль
Университе Де Нант
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    • C12N2760/18011Paramyxoviridae
    • C12N2760/18411Morbillivirus, e.g. Measles virus, canine distemper
    • C12N2760/18461Methods of inactivation or attenuation
    • C12N2760/18462Methods of inactivation or attenuation by genetic engineering

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RU2015128913A 2013-01-24 2014-01-20 Применение генетически модифицированного патогенного вируса кори с улучшенными проапоптотическими свойствами (вирус mv-deltac) в терапии рака RU2700083C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP13305086.4A EP2759301A1 (en) 2013-01-24 2013-01-24 Use of a genetically modified infectious measles virus with enhanced pro-apoptotic properties (MV-DeltaC virus)
EP13305086.4 2013-01-24
PCT/EP2014/051063 WO2014114605A1 (en) 2013-01-24 2014-01-20 Use of a genetically modified infectious measles virus with enhanced pro-apoptotic properties (mv-deltac virus) in cancer therapy

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RU2015128913A RU2015128913A (ru) 2017-03-02
RU2700083C2 true RU2700083C2 (ru) 2019-09-12

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RU2015128913A RU2700083C2 (ru) 2013-01-24 2014-01-20 Применение генетически модифицированного патогенного вируса кори с улучшенными проапоптотическими свойствами (вирус mv-deltac) в терапии рака

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US (3) US9889193B2 (enExample)
EP (2) EP2759301A1 (enExample)
JP (1) JP6382223B2 (enExample)
CN (1) CN107223055A (enExample)
BR (1) BR112015017692B1 (enExample)
CA (1) CA2898370C (enExample)
DK (1) DK2948157T3 (enExample)
ES (1) ES2700749T3 (enExample)
PL (1) PL2948157T3 (enExample)
RU (1) RU2700083C2 (enExample)
WO (1) WO2014114605A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2759301A1 (en) * 2013-01-24 2014-07-30 Institut Pasteur Use of a genetically modified infectious measles virus with enhanced pro-apoptotic properties (MV-DeltaC virus)
CN107085095A (zh) * 2017-03-02 2017-08-22 江苏华冠生物技术股份有限公司 用作酶联试剂盒包被抗原的麻疹病毒裂解液的制备方法
CA3082961A1 (en) * 2017-12-01 2019-06-06 Gerd Sutter Immuno-modulated replication-efficient vaccinia virus strain

Citations (1)

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Publication number Priority date Publication date Assignee Title
WO2012022495A1 (en) * 2010-08-20 2012-02-23 Lauer Ulrich M Oncolytic measles virus

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US7118740B1 (en) 2000-09-22 2006-10-10 Mayo Foundation For Medical Education And Research Method for limiting the growth of cancer cells using an attenuated measles virus
PT1375512E (pt) 2002-06-20 2009-09-23 Pasteur Institut Adnc infeccioso de uma estirpe de vacina aprovada do vírus do sarampo. utilização de composições imunogénicas
CA2432738A1 (en) 2003-02-26 2004-08-26 Philippe Despres New dengue and west nile viruses proteins and genes coding the foregoing, and their use in vaccinal, therapeutic and diagnostic applications
CA2508266A1 (fr) 2005-06-20 2006-12-20 Institut Pasteur Polypeptides chimeriques et leurs applications therapeutiques contre une infection a flaviviridae
ES2423518T3 (es) 2006-12-22 2013-09-20 Institut Pasteur Células y metodología para generar virus de ARN de cadena de sentido negativo no segmentada
EP2058003A1 (en) 2007-10-10 2009-05-13 Institut National De La Sante Et De La Recherche Medicale (Inserm) Medicaments and methods for treating mesothelioma
US9399062B2 (en) * 2011-01-18 2016-07-26 Christopher D. Richardson PVRL4 (Nectin4) is a receptor for measles virus
EP2759301A1 (en) * 2013-01-24 2014-07-30 Institut Pasteur Use of a genetically modified infectious measles virus with enhanced pro-apoptotic properties (MV-DeltaC virus)

Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
WO2012022495A1 (en) * 2010-08-20 2012-02-23 Lauer Ulrich M Oncolytic measles virus

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
FRANK RADECKE et al., The Nonstructural C Protein Is Not Essential for Multiplication of Edmonston B Strain Measles Virus in Cultured Cells, VIROLOGY 1996, Vol.217, pp. 418-421. *
FRANK RADECKE et al., The Nonstructural C Protein Is Not Essential for Multiplication of Edmonston B Strain Measles Virus in Cultured Cells, VIROLOGY 1996, Vol.217, pp. 418-421. KAORU TAKEUCHI et al., Stringent Requirement for the C Protein of Wild-Type Measles Virus for Growth both In Vitro and in Macaques, JOURNAL OF VIROLOGY, June 2005, Vol. 79, No. 12, pp.7838-7844. JEAN-BAPTISTE GUILLERME et al., Measles Virus Vaccine-Infected Tumor Cells Induce Tumor Antigen Cross-Presentation by Human Plasmacytoid Dendritic Cells, Clin Cancer Res January 21, 2013, Vol.19, No.5, pp.1147-1159. *
GUY UNGERECHTS et al., Mantle cell lymphoma salvage regimen: synergy between a reprogrammed oncolytic virus and two chemotherapeutics, Gene Ther. 2010 December ; 17(12): 1506-1516. *
GUY UNGERECHTS et al., Mantle cell lymphoma salvage regimen: synergy between a reprogrammed oncolytic virus and two chemotherapeutics, Gene Ther. 2010 December ; 17(12): 1506-1516. Ю.И. АММУР и др., ВИРУС КОРИ КАК ОНКОЛИТИЧЕСКИЙ АГЕНТ, Вопросы вирусологии, 2013, S1, стр.116-131. *
JEAN-BAPTISTE GUILLERME et al., Measles Virus Vaccine-Infected Tumor Cells Induce Tumor Antigen Cross-Presentation by Human Plasmacytoid Dendritic Cells, Clin Cancer Res January 21, 2013, Vol.19, No.5, pp.1147-1159. *
KAORU TAKEUCHI et al., Stringent Requirement for the C Protein of Wild-Type Measles Virus for Growth both In Vitro and in Macaques, JOURNAL OF VIROLOGY, June 2005, Vol. 79, No. 12, pp.7838-7844. *
Ю.И. АММУР и др., ВИРУС КОРИ КАК ОНКОЛИТИЧЕСКИЙ АГЕНТ, Вопросы вирусологии, 2013, S1, стр.116-131. *

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PL2948157T3 (pl) 2019-03-29
DK2948157T3 (en) 2019-01-07
US9889193B2 (en) 2018-02-13
BR112015017692A2 (pt) 2019-11-19
US10314905B2 (en) 2019-06-11
ES2700749T3 (es) 2019-02-19
BR112015017692B1 (pt) 2021-11-03
US20180221469A1 (en) 2018-08-09
US10980873B2 (en) 2021-04-20
US20200016260A1 (en) 2020-01-16
CN107223055A (zh) 2017-09-29
CA2898370C (en) 2020-01-14
EP2948157B1 (en) 2018-10-10
CA2898370A1 (en) 2014-07-31
EP2948157A1 (en) 2015-12-02
WO2014114605A1 (en) 2014-07-31
JP6382223B2 (ja) 2018-08-29
EP2759301A1 (en) 2014-07-30
JP2016506722A (ja) 2016-03-07
RU2015128913A (ru) 2017-03-02
US20150359873A1 (en) 2015-12-17

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