CN107223055A - 具有增强的促凋亡特性的基因修饰的传染性麻疹病毒(mv-deltac病毒)在癌症治疗中的用途 - Google Patents

具有增强的促凋亡特性的基因修饰的传染性麻疹病毒(mv-deltac病毒)在癌症治疗中的用途 Download PDF

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Publication number
CN107223055A
CN107223055A CN201480017539.6A CN201480017539A CN107223055A CN 107223055 A CN107223055 A CN 107223055A CN 201480017539 A CN201480017539 A CN 201480017539A CN 107223055 A CN107223055 A CN 107223055A
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deltac
cells
cancer
measles virus
pdc
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CN201480017539.6A
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Chinese (zh)
Inventor
F·坦吉
M·格雷瓜尔
J-F·丰特诺
J-B·吉耶尔姆
C·孔布勒代
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Centre National de la Recherche Scientifique CNRS
Universite de Nantes
Institut National de la Sante et de la Recherche Medicale INSERM
Institut Pasteur
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Centre National de la Recherche Scientifique CNRS
Universite de Nantes
Institut National de la Sante et de la Recherche Medicale INSERM
Institut Pasteur
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Publication of CN107223055A publication Critical patent/CN107223055A/zh
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CN201480017539.6A 2013-01-24 2014-01-20 具有增强的促凋亡特性的基因修饰的传染性麻疹病毒(mv-deltac病毒)在癌症治疗中的用途 Pending CN107223055A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP13305086.4A EP2759301A1 (en) 2013-01-24 2013-01-24 Use of a genetically modified infectious measles virus with enhanced pro-apoptotic properties (MV-DeltaC virus)
EP13305086.4 2013-01-24
PCT/EP2014/051063 WO2014114605A1 (en) 2013-01-24 2014-01-20 Use of a genetically modified infectious measles virus with enhanced pro-apoptotic properties (mv-deltac virus) in cancer therapy

Publications (1)

Publication Number Publication Date
CN107223055A true CN107223055A (zh) 2017-09-29

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CN201480017539.6A Pending CN107223055A (zh) 2013-01-24 2014-01-20 具有增强的促凋亡特性的基因修饰的传染性麻疹病毒(mv-deltac病毒)在癌症治疗中的用途

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US (3) US9889193B2 (enExample)
EP (2) EP2759301A1 (enExample)
JP (1) JP6382223B2 (enExample)
CN (1) CN107223055A (enExample)
BR (1) BR112015017692B1 (enExample)
CA (1) CA2898370C (enExample)
DK (1) DK2948157T3 (enExample)
ES (1) ES2700749T3 (enExample)
PL (1) PL2948157T3 (enExample)
RU (1) RU2700083C2 (enExample)
WO (1) WO2014114605A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2759301A1 (en) * 2013-01-24 2014-07-30 Institut Pasteur Use of a genetically modified infectious measles virus with enhanced pro-apoptotic properties (MV-DeltaC virus)
CN107085095A (zh) * 2017-03-02 2017-08-22 江苏华冠生物技术股份有限公司 用作酶联试剂盒包被抗原的麻疹病毒裂解液的制备方法
CA3082961A1 (en) * 2017-12-01 2019-06-06 Gerd Sutter Immuno-modulated replication-efficient vaccinia virus strain

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101868249A (zh) * 2007-10-10 2010-10-20 巴斯德研究所 治疗间皮瘤的药物和方法
WO2012022495A1 (en) * 2010-08-20 2012-02-23 Lauer Ulrich M Oncolytic measles virus

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Publication number Priority date Publication date Assignee Title
US7118740B1 (en) 2000-09-22 2006-10-10 Mayo Foundation For Medical Education And Research Method for limiting the growth of cancer cells using an attenuated measles virus
PT1375512E (pt) 2002-06-20 2009-09-23 Pasteur Institut Adnc infeccioso de uma estirpe de vacina aprovada do vírus do sarampo. utilização de composições imunogénicas
CA2432738A1 (en) 2003-02-26 2004-08-26 Philippe Despres New dengue and west nile viruses proteins and genes coding the foregoing, and their use in vaccinal, therapeutic and diagnostic applications
CA2508266A1 (fr) 2005-06-20 2006-12-20 Institut Pasteur Polypeptides chimeriques et leurs applications therapeutiques contre une infection a flaviviridae
ES2423518T3 (es) 2006-12-22 2013-09-20 Institut Pasteur Células y metodología para generar virus de ARN de cadena de sentido negativo no segmentada
US9399062B2 (en) * 2011-01-18 2016-07-26 Christopher D. Richardson PVRL4 (Nectin4) is a receptor for measles virus
EP2759301A1 (en) * 2013-01-24 2014-07-30 Institut Pasteur Use of a genetically modified infectious measles virus with enhanced pro-apoptotic properties (MV-DeltaC virus)

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101868249A (zh) * 2007-10-10 2010-10-20 巴斯德研究所 治疗间皮瘤的药物和方法
WO2012022495A1 (en) * 2010-08-20 2012-02-23 Lauer Ulrich M Oncolytic measles virus

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
ALEXANDRA VALSAMAKIS等: "Recombinant Measles Viruses with Mutations in the C, V, or F Gene Have Altered Growth Phenotypes In Vivo", 《JOURNAL OF VIROLOGY》 *
ANN M. TOTH等: "Protein Kinase PKR Mediates the Apoptosis Induction and Growth Restriction Phenotypes of C Protein-Deficient Measles Virus", 《JOURNAL OF VIROLOGY》 *
JEAN-BAPTISTE GUILLERME等: "Measles Virus Vaccine–Infected Tumor Cells Induce Tumor Antigen Cross-Presentation by Human Plasmacytoid Dendritic Cells", 《AMERICAN ASSOCIATION FOR CANCER RESEARCH》 *
JURJEN TEL等: "Natural Human Plasmacytoid Dendritic Cells Induce Antigen-Specific T-Cell Responses in Melanoma Patients", 《CANCER RESEARCH》 *
PATRICIA DEVAUX等: "Attenuation of V- or C-Defective Measles Viruses: Infection Control by the Inflammatory and Interferon Responses of Rhesus Monkeys", 《JOURNAL OF VIROLOGY》 *

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PL2948157T3 (pl) 2019-03-29
DK2948157T3 (en) 2019-01-07
US9889193B2 (en) 2018-02-13
BR112015017692A2 (pt) 2019-11-19
US10314905B2 (en) 2019-06-11
ES2700749T3 (es) 2019-02-19
BR112015017692B1 (pt) 2021-11-03
US20180221469A1 (en) 2018-08-09
US10980873B2 (en) 2021-04-20
US20200016260A1 (en) 2020-01-16
CA2898370C (en) 2020-01-14
EP2948157B1 (en) 2018-10-10
CA2898370A1 (en) 2014-07-31
EP2948157A1 (en) 2015-12-02
WO2014114605A1 (en) 2014-07-31
JP6382223B2 (ja) 2018-08-29
RU2700083C2 (ru) 2019-09-12
EP2759301A1 (en) 2014-07-30
JP2016506722A (ja) 2016-03-07
RU2015128913A (ru) 2017-03-02
US20150359873A1 (en) 2015-12-17

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