RU2683781C2 - Диагностика и лечение синдрома раздраженного кишечника и воспалительного заболевания кишечника - Google Patents

Диагностика и лечение синдрома раздраженного кишечника и воспалительного заболевания кишечника Download PDF

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RU2683781C2
RU2683781C2 RU2016116766A RU2016116766A RU2683781C2 RU 2683781 C2 RU2683781 C2 RU 2683781C2 RU 2016116766 A RU2016116766 A RU 2016116766A RU 2016116766 A RU2016116766 A RU 2016116766A RU 2683781 C2 RU2683781 C2 RU 2683781C2
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antibodies
vinculin
ibs
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cdt
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Марк ПИМЕНТЕЛЬ
Кристофер Чан
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Седарс-Синаи Медикал Сентер
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/205Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Campylobacter (G)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/06Gastro-intestinal diseases
    • G01N2800/065Bowel diseases, e.g. Crohn, ulcerative colitis, IBS

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  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
RU2016116766A 2013-10-09 2014-10-09 Диагностика и лечение синдрома раздраженного кишечника и воспалительного заболевания кишечника RU2683781C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361888658P 2013-10-09 2013-10-09
US61/888,658 2013-10-09
PCT/US2014/059957 WO2015054529A1 (en) 2013-10-09 2014-10-09 Diagnosis and treatment of irritable bowel syndrome and inflammatory bowel disease

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RU2016116766A RU2016116766A (ru) 2017-11-15
RU2683781C2 true RU2683781C2 (ru) 2019-04-02

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US (2) US9851361B2 (OSRAM)
EP (1) EP3054977B1 (OSRAM)
JP (1) JP6567509B2 (OSRAM)
KR (1) KR102259588B1 (OSRAM)
CN (1) CN105744956B (OSRAM)
AU (2) AU2014331841B2 (OSRAM)
BR (1) BR112016007474A2 (OSRAM)
CA (1) CA2923651C (OSRAM)
CL (1) CL2016000820A1 (OSRAM)
ES (1) ES2892905T3 (OSRAM)
IL (1) IL244971B2 (OSRAM)
MX (1) MX383423B (OSRAM)
NZ (1) NZ717633A (OSRAM)
PE (1) PE20160882A1 (OSRAM)
PL (1) PL3054977T3 (OSRAM)
PT (1) PT3054977T (OSRAM)
RU (1) RU2683781C2 (OSRAM)
SG (1) SG11201601733VA (OSRAM)
WO (1) WO2015054529A1 (OSRAM)

Cited By (2)

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US10527621B2 (en) 2009-02-11 2020-01-07 Cedars-Sinai Medical Center Antibody to cytolethal distending toxin of Campylobacter jejuni
US12222352B2 (en) 2017-01-30 2025-02-11 Cedars-Sinai Medical Center Diagnosis of scleroderma

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MX383428B (es) 2012-09-17 2025-03-13 Cedars Sinai Medical Center Determinaciòn de trastornos de la motilidad de los intestinos y la vejiga, y de la fibromialgia.
US9851361B2 (en) 2013-10-09 2017-12-26 Cedars-Sinai Medical Center Methods of comparing anti-vinculin and anti-cytolethal distending toxin antibodies as they relate to irritable bowel syndrome
RU2706361C2 (ru) 2014-10-09 2019-11-18 Седарс-Синаи Медикал Сентер Способы и системы для отличия синдрома раздраженного кишечника от воспалительного заболевания кишечника и глютеновой болезни
CN106053827A (zh) * 2016-05-17 2016-10-26 上海凯璟生物科技有限公司 一种肠易激综合症标志物Vinculin抗体检测试剂盒及其制备方法
CN105784989A (zh) * 2016-05-17 2016-07-20 上海凯璟生物科技有限公司 一种肠易激综合症标志物CdtB抗体检测试剂盒及其制备方法
KR20230003433A (ko) * 2016-05-20 2023-01-05 세다르스-신나이 메디칼 센터 유전자에 기반한 염증성 장 질환의 진단
RU2763258C1 (ru) * 2020-07-13 2021-12-28 Евгения Николаевна Воронина Способ дифференциальной диагностики воспалительных заболеваний кишечника у детей по комплексу клинико-анамнестических, лабораторных и инструментальных критериев

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RU2706361C2 (ru) 2014-10-09 2019-11-18 Седарс-Синаи Медикал Сентер Способы и системы для отличия синдрома раздраженного кишечника от воспалительного заболевания кишечника и глютеновой болезни
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WO2005029091A2 (en) * 2003-09-15 2005-03-31 Oklahoma Medical Research Foundation Method of using cytokine assays to diagnose, treat, and evaluate inflammatory and autoimmune diseases
RU2397178C1 (ru) * 2009-02-27 2010-08-20 Федеральное государственное учреждение науки "Центральный научно-исследовательский институт эпидемиологии" Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека Диагностическая тест-система в формате иммуночипа и способ серологической дифференциальной диагностики сифилиса

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10527621B2 (en) 2009-02-11 2020-01-07 Cedars-Sinai Medical Center Antibody to cytolethal distending toxin of Campylobacter jejuni
US12222352B2 (en) 2017-01-30 2025-02-11 Cedars-Sinai Medical Center Diagnosis of scleroderma

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CN105744956B (zh) 2021-07-20
NZ717633A (en) 2021-07-30
US20180196063A1 (en) 2018-07-12
ES2892905T3 (es) 2022-02-07
JP2017502253A (ja) 2017-01-19
IL244971A0 (en) 2016-05-31
MX2016004167A (es) 2016-06-24
IL244971B2 (en) 2023-12-01
CA2923651C (en) 2023-03-14
US9851361B2 (en) 2017-12-26
US20170038393A1 (en) 2017-02-09
US10352944B2 (en) 2019-07-16
KR20160062161A (ko) 2016-06-01
CN105744956A (zh) 2016-07-06
WO2015054529A1 (en) 2015-04-16
AU2020203468A1 (en) 2020-06-18
AU2014331841B2 (en) 2020-03-12
CL2016000820A1 (es) 2016-09-23
PT3054977T (pt) 2021-10-14
BR112016007474A2 (pt) 2017-09-12
RU2016116766A (ru) 2017-11-15
KR102259588B1 (ko) 2021-06-02
PE20160882A1 (es) 2016-09-14
CA2923651A1 (en) 2015-04-16
HK1221898A1 (zh) 2017-06-16
MX383423B (es) 2025-03-14
EP3054977B1 (en) 2021-07-21
JP6567509B2 (ja) 2019-08-28
AU2014331841A1 (en) 2016-03-24
EP3054977A4 (en) 2017-04-12
EP3054977A1 (en) 2016-08-17
PL3054977T3 (pl) 2021-12-20
IL244971B1 (en) 2023-08-01
SG11201601733VA (en) 2016-04-28

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